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by Mavaddat, N and Barrowdale, D and Anulis, I.L and Domchek, S.M and Eccles, D and Nevanlinna, H and Ramus, S.J and Spurdle, A and Robson, M and Sherman, M and Mulligan, A.M and Couch, F.J and Engel, C and McGuffog, L and Healey, S and Sinilnikova, O.M and Southey, M.C and Terry, M.B and Goldgar, D and O'Malley, F and John, E.M and Janavicius, R and Tihomirova, L and Hansen, T.V and Nielsen, F.C and Osorio, A and Stavropoulou, A and Benitez, J and Manoukian, S and Peissel, B and Barile, M and Volorio, S and Pasini, B and Dolcetti, R and Putignano, A.L and Ottini, L and Radice, P and Hamann, U and Rashid, M.U and Hogervorst, F.B.L and Kriege, M and Luijt, R.B. van der and Peock, S and Frost, D and Evans, D.G and Brewer, C and Walker, L and Rogers, M.T and Side, L.E and Houghton, C and Weaver, J and Godwin, A.K and Schmutzler, R.K and Wappenschmidt, B and Meindl, A and Kast, K and Arnold, N and Niederacher, D and Sutter, C and Deissler, H and Gadzicki, D and Preisler-Adams, S and Varon-Mateeva, R and Schonbuchner, I and Gevensleben, H and Stoppa-Lyonnet, D and Belotti, M and Barjhoux, L and Isaacs, C and Peshkin, B.N and Caldes, T and Hoya, M. de la and Canadas, C and Heikkinen, T and Heikkila, P and Aittomaki, K and Blanco, I and Lazaro, C and Brunet, J and Agnarsson, B.A and Arason, A and Barkardottir, R.B and Dumont, M and Simard, J and Montagna, M and Agata, S and D'Anea, E and Yan, M and Fox, S and Rebbeck, T.R and Rubinstein, W and Tung, N and Garber, J.E and Wang, X and Fredericksen, Z and Pankratz, V.S and Lindor, N.M and Szabo, C and Offit, K and Sakr, R and ... and kConFab Investigators and HEBON and EMBRACE and GEMO Study Collaborators and SWE-BRCA Collaborators and Consortium Investigators Modifiers and Consortium of Investigators of Modifiers of BRCA1/2 and for EMBRACE and for HEBON and for the Consortium of Investigators of Modifiers of BRCA1/2 and for SWE-BRCA Collaborators and for kConFab Investigators and for GEMO Study Collaborators and Onkologi och Patologi, MV and EpiHealth: Epidemiology for Health and Lund University and Oncology and Pathology, MV and Lunds universitet
Cancer Epidemiology, Biomarkers & Prevention, ISSN 1055-9965, 2012, Volume 21, Issue 1, pp. 134 - 147
Journal Article
by Jakubowska, A and Rozkrut, D and Antoniou, A and Hamann, U and Scott, R. J and McGuffog, L and Healy, S and Sinilnikova, O. M and Rennert, G and Lejbkowicz, F and Flugelman, A and Anulis, I. L and Glendon, G and Ozcelik, H and Thomassen, M and Paligo, M and Aretini, P and Kantala, J and Aroer, B and Von Wachenfeldt, A and Liljegren, A and Loman, N and Herbst, K and Kristoffersson, U and Rosenquist, R and Karlsson, P and Stenmark-Askmalm, M and Melin, B and Nathanson, K. L and Domchek, S. M and Byrski, T and Huzarski, T and Gronwald, J and Menkiszak, J and Cybulski, C and Serrano, P and Osorio, A and Cajal, T. R and Tsitlaidou, M and Benítez, J and Gilbert, M and Rookus, M and Aalfs, C. M and Kluijt, I and Boessenkool-Pape, J. L and Meijers-Heijboer, H. E. J and Oosterwijk, J. C and van Asperen, C. J and Blok, M. J and Nelen, M. R and van den Ouweland, A. M. W and Seynaeve, C and van der Luijt, R. B and Devilee, P and Easton, D. F and Peock, S and Frost, D and Platte, R and Ellis, S. D and Fineberg, E and Evans, D. G and Lalloo, F and Eeles, R and Jacobs, C and Adlard, J and Davidson, R and Eccles, D and Cole, T and Cook, J and Godwin, A and Bove, B and Stoppa-Lyonnet, D and Caux-Moncoutier, V and Belotti, M and Tirapo, C and Mazoyer, S and Barjhoux, L and Boutry-Kryza, N and Pujol, P and Coupier, I and Peyrat, J.-P and Vennin, P and Muller, D and Fricker, J.-P and Venat-Bouvet, L and Johannsson, O. Th and Isaacs, C and Schmutzler, R and Wappenschmidt, B and Meindl, A and Arnold, N and Varon-Mateeva, R and Niederacher, D and Sutter, C and Deissler, H and Preisler-Adams, S and Simard, J and Soucy, P and Durocher, F and Chenevix-Trench, G and ... and KConFab and EMBRACE and GEMO Study Collaborators and CIMBA and SWE BRCA and HEBON and OCGN and CIMBA, the Consortium of Investigators of Modifiers of BRCA1/2-Related Cancer and SWE-BRCA and on behalf of CIMBA, the Consortium of Investigators of Modifiers of BRCA1/2-Related Cancer and Medicinska fakulteten and Institutionen för strålningsvetenskaper and Onkologi and Umeå universitet
British journal of cancer, ISSN 0007-0920, 2012, Volume 106, Issue 12, pp. 2016 - 2024
Journal Article
by Ramus, S.J and Antoniou, A.C and Kuchenbaecker, K.B and Soucy, P and Beesley, J and Chen, X and McGuffog, L and Sinilnikova, O.M and Healey, S and Barrowdale, D and Lee, A and Thomassen, M and Gerdes, A.M and Kruse, T.A and Jensen, U.B and Skytte, A.B and Caligo, M.A and Liljegren, A and Lindblom, A and Olsson, H and Kristoffersson, U and Stenmark-Askmalm, M and Melin, B and Swe, B and Domchek, S.M and Nathanson, K.L and Rebbeck, T.R and Jakubowska, A and Lubinski, J and Jaworska, K and Durda, K and Zlowocka, E and Gronwald, J and Huzarski, T and Byrski, T and Cybulski, C and Toloczko-Grabarek, A and Osorio, A and Benitez, J and Duran, M and Tejada, M.I and Hamann, U and Rookus, M and van Leeuwen, F.E and Aalfs, C.M and Meijers-Heijboer, H.E and Asperen, C.J. van and van Roozendaal, K.E and Hoogerbrugge-van der Linden, N and Collee, J.M and Kriege, M and van der Luijt, R.B and Hebon and Embrace and Peock, S and Frost, D and Ellis, S.D and Platte, R and Fineberg, E and Evans, D.G and Lalloo, F and Jacobs, C and Eeles, R and Adlard, J and Davidson, R and Eccles, D and Cole, T and Cook, J and Paterson, J and Douglas, F and Brewer, C and Hodgson, S and Morrison, P.J and Walker, L and Porteous, M.E and Kennedy, M.J and Pathak, H and Godwin, A.K and Stoppa-Lyonnet, D and Caux-Moncoutier, V and de Pauw, A and Gauthier-Villars, M and Mazoyer, S and Leone, M and Calender, A and Lasset, C and Bonadona, V and Hardouin, A and Berthet, P and Bignon, Y.J and Uhrhammer, N and Faivre, L and Loustalot, C and Gemo and Buys, S and Daly, M and Miron, A and Terry, M.B and Chung, W.K and John, E.M and ... and KConFab and EMBRACE and Consortium Investigators Modifiers and GEMO and HEBON and Ocgn and SWE-BRCA and Medicinska fakulteten and Institutionen för strålningsvetenskaper and Onkologi and Umeå universitet
Human Mutation, ISSN 1059-7794, 2012, Volume 33, Issue 4, pp. 690 - 702
Germline mutations in BRCA1 and BRCA2 are associated with increased risks of breast and ovarian cancer. A genome-wide association study (GWAS) identified six... 
association | BRCA1 | SNP | BRCA2 | ovarian cancer | GENETICS & HEREDITY | Càncer de mama | Càncer d'ovari | Breast cancer | Ovarian cancer | Clinical Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Cancer and Oncology | Klinisk medicin | Cancer och onkologi
Journal Article
by Meeks, H.D and Song, H and Michailidou, K and Bolla, M.K and Dennis, J and Wang, Q and Barrowdale, D and Frost, D and McGuffog, L and Ellis, S and Feng, B and Buys, S.S and Hopper, J.L and Southey, M.C and Tesoriero, A and James, P.A and Bruinsma, F and Campbell, I.G and Broeks, A and Schmidt, M.K and Hogervorst, F.B and Beckman, M.W and Fasching, P.A and Fletcher, O and Johnson, N and Sawyer, E.J and Riboli, E and Banerjee, S and Menon, U and Tomlinson, I and Burwinkel, B and Hamann, U and Marme, F and Rudolph, A and Janavicius, R and Tihomirova, L and Tung, N and Garber, J and Cramer, D and Terry, K.L and Poole, E.M and Tworoger, S.S and Dorfling, C.M and Rensburg, E.J. van and Godwin, A.K and Guenel, P and Truong, T and Stoppa-Lyonnet, D and Damiola, F and Mazoyer, S and Sinilnikova, O.M and Isaacs, C and Maugard, C and Bojesen, S.E and Flyger, H and Gerdes, A.M and Hansen, T.V and Jensen, A and Kjaer, S.K and Hogdall, C and Hogdall, E and Pedersen, I.S and Thomassen, M and Benitez, J and Gonzalez-Neira, A and Osorio, A and Mde, L. Hoya and Segura, P.P and Diez, O and Lazaro, C and Brunet, J and Anton-Culver, H and Eunjung, L and John, E.M and Neuhausen, S.L and Ding, Y.C and Castillo, D. Del and Weitzel, J.N and Ganz, P.A and Nussbaum, R.L and Chan, S.B and Karlan, B.Y and Lester, J and Wu, A and Gayther, S and Ramus, S.J and Sieh, W and Whittermore, A.S and Monteiro, A.N and Phelan, C.M and Terry, M.B and Piedmonte, M and Offit, K and Robson, M and Levine, D and Moysich, K.B and Cannioto, R and Olson, S.H and Daly, M.B and Nathanson, K.L and ...
Journal of the National Cancer Institute, ISSN 0027-8874, 2016, Volume 108, Issue 2
BACKGROUND: The K3326X variant in BRCA2 (BRCA2*c.9976A>T; p.Lys3326*; rs11571833) has been found to be associated with small increased risks of breast cancer.... 
Journal Article
by Rebbeck, T.R and Mitra, N and Wan, F and Sinilnikova, O.M and Healey, S and McGuffog, L and Mazoyer, S and Chenevix-Trench, G and Easton, D.F and Antoniou, A.C and Nathanson, K.L and Laitman, Y and Kushnir, A and Paluch-Shimon, S and Berger, R and Zidan, J and Friedman, E and Ehrencrona, H and Stenmark-Askmalm, M and Einbeigi, Z and Loman, N and Harbst, K and Rantala, J and Melin, B and Huo, D and Olopade, O.I and Seldon, J and Ganz, P.A and Nussbaum, R.L and Chan, S.B and Odunsi, K and Gayther, S.A and Domchek, S.M and Arun, B.K and Lu, K.H and Mitchell, G and Karlan, B.Y and Walsh, C and Lester, J and Godwin, A.K and Pathak, H and Ross, E and Daly, M.B and Whittemore, A.S and John, E.M and Miron, A and Terry, M.B and Chung, W.K and Goldgar, D.E and Buys, S.S and Janavicius, R and Tihomirova, L and Tung, N and Dorfling, C.M and Rensburg, E.J. van and Steele, L and Neuhausen, S.L and Ding, Y.C and Ejlertsen, B and Gerdes, A.M and Hansen, T and Ramon Y Cajal, T and Osorio, A and Benitez, J and Godino, J and Tejada, M.I and Duran, M and Weitzel, J.N and Bobolis, K.A and Sand, S.R and Fontaine, A and Savarese, A and Pasini, B and Peissel, B and Bonanni, B and Zaffaroni, D and Vignolo-Lutati, F and Scuvera, G and Giannini, G and Bernard, L and Genuardi, M and Radice, P and Dolcetti, R and Manoukian, S and Pensotti, V and Gismondi, V and Yannoukakos, D and Fostira, F and Garber, J and Torres, D and Rashid, M.U and Hamann, U and Peock, S and Frost, D and Platte, R and Evans, D.G and Eeles, R and Davidson, R and Eccles, D and Cole, T and ...
JAMA : Journal of the American Medical Association, ISSN 0098-7484, 2015, Volume 313, pp. 1347 - 1361
IMPORTANCE: Limited information about the relationship between specific mutations in BRCA1 or BRCA2 (BRCA1/2) and cancer risk exists. OBJECTIVE: To identify... 
Journal Article
by Martrat, G and Maxwell, C.A and Tominaga, E and Porta-de-la-Riva, M and Bonifaci, N and Gomez-Baldo, L and Bogliolo, M and Lazaro, C and Blanco, I and Brunet, J and Aguilar, H and Fernandez-Roiguez, J and Seal, S and Renwick, A and Rahman, N and Kuehl, J and Neveling, K and Schindler, D and Ramirez, M.J and Castella, M and Hernandez, G and Easton, D.F and Peock, S and Cook, M and Oliver, C.T and Frost, D and Platte, R and Evans, D.G and Lalloo, F and Eeles, R and Izatt, L and Chu, C and Davidson, R and Ong, K.R and Cook, J and Douglas, F and Hodgson, S and Brewer, C and Morrison, P.J and Porteous, M and Peterlongo, P and Manoukian, S and Peissel, B and Zaffaroni, D and Roversi, G and Barile, M and Viel, A and Pasini, B and Ottini, L and Putignano, A.L and Savarese, A and Bernard, L and Radice, P and Healey, S and Spurdle, A and Chen, X and Beesley, J and Rookus, M.A and Verhoef, S and Tilanus-Linthorst, M.A and Vreeswijk, M.P and van Asperen, C.J and Bodmer, D and Ausems, M.G.E.M and van Os, T.A and Blok, M.J and Meijers-Heijboer, H.E.J and Hogervorst, F.B.L and Goldgar, D.E and Buys, S and John, E.M and Miron, A and Southey, M and Daly, M.B and Harbst, K and Borg, A and Rantala, J and Barbany-Bustinza, G and Ehrencrona, H and Stenmark-Askmalm, M and Kaufman, B and Laitman, Y and Milgrom, R and Friedman, E and Domchek, S.M and Nathanson, K.L and Rebbeck, T.R and Johannsson, O.T and Couch, F.J and Wang, X and Fredericksen, Z and Cuaas, D and Moreno, V and Pientka, F.K and Depping, R and Caldes, T and Osorio, A and Benitez, J and Bueren, J and Heikkinen, T and ...
Breast Cancer Research, ISSN 1465-5411, 2011, Volume 13, Issue 2
Introduction: Proteins encoded by Fanconi anemia (FA) and/or breast cancer (BrCa) susceptibility genes cooperate in a common DNA damage repair signaling... 
Journal Article
by Kuchenbaecker, K.B and Ramus, S.J and Tyrer, J and Lee, A and Shen, H.C and Beesley, J and Lawrenson, K and McGuffog, L and Healey, S and Lee, J.M and Spindler, T.J and Lin, Y.G and Pejovic, T and Bean, Y and Li, Q and Coetzee, S and Hazelett, D and Miron, A and Southey, M and Terry, M.B and Goldgar, D.E and Buys, S.S and Janavicius, R and Dorfling, C.M and Rensburg, E.J. van and Neuhausen, S.L and Ding, Y.C and Hansen, T.V and Jonson, L and Gerdes, A.M and Ejlertsen, B and Barrowdale, D and Dennis, J and Benitez, J and Osorio, A and Garcia, M.J and Komenaka, I and Weitzel, J.N and Ganschow, P and Peterlongo, P and Bernard, L and Viel, A and Bonanni, B and Peissel, B and Manoukian, S and Radice, P and Papi, L and Ottini, L and Fostira, F and Konstantopoulou, I and Garber, J and Frost, D and Perkins, J and Platte, R and Ellis, S and Embrace and Godwin, A.K and Schmutzler, R.K and Meindl, A and Engel, C and Sutter, C and Sinilnikova, O.M and Damiola, F and Mazoyer, S and Stoppa-Lyonnet, D and Claes, K and Leeneer, K. De and Kirk, J and Roiguez, G.C and Piedmonte, M and O'Malley, D.M and Hoya, M. de la and Caldes, T and Aittomaki, K and Nevanlinna, H and Collee, J.M and Rookus, M.A and Oosterwijk, J.C and Tihomirova, L and Tung, N and Hamann, U and Isaccs, C and Tischkowitz, M and Imyanitov, E.N and Caligo, M.A and Campbell, I.G and Hogervorst, F.B and Olah, E and Diez, O and Blanco, I and Brunet, J and Lazaro, C and Pujana, M.A and Jakubowska, A and Gronwald, J and Lubinski, J and Sukiennicki, G and Massuger, L.F.A.G and Altena, A.M. van and Aben, K.K.H and ...
Nature Genetics, ISSN 1061-4036, 2015, Volume 47, Issue 2, pp. 164 - 171
Genome-wide association studies (GWAS) have identified 12 epithelial ovarian cancer (EOC) susceptibility alleles. The pattern of association at these loci is... 
Cèl·lules epitelials | Càncer d'ovari | Developmental genetics | Human genome | Epithelial cells | Genètica del desenvolupament | Nucleotides | Genoma humà | Nucleòtids | Ovarian cancer
Journal Article
by Martrat, G and Maxwell, C.M and Tominaga, E and Porta-de-la-Riva, M and Bonifaci, N and Gomez-Baldo, L and Bogliolo, M and Lazaro, C and Blanco, I and Brunet, J and Aguilar, H and Fernandez-Roiguez, J and Seal, S and Renwick, A and Rahman, N and Kuhl, J and Neveling, K and Schindler, D and Ramirez, M.J and Castella, M and Hernandez, G and Easton, D.F and Peock, S and Cook, M and Oliver, C.T and Frost, D and Platte, R and Evans, D.G and Lalloo, F and Eeles, R and Izatt, L and Chu, C and Davidson, R and Ong, K.R and Cook, J and Douglas, F and Hodgson, S and Brewer, C and Morrison, P.J and Porteous, M and Peterlongo, P and Manoukian, S and Peissel, B and Zaffaroni, D and Roversi, G and Barile, M and Viel, A and Pasini, B and Ottini, L and Putignano, A.L and Savarese, A and Bernard, L and Radice, P and Healey, S and Spurdle, A and Chen, X and Beesley, J and Rookus, M.A and Verhoef, S and Tilanus-Linthorst, M.A and Vreeswijk, M.P and Asperen, C.J. van and Bodmer, D and Ausems, M.G and Os, T.A. van and Blok, M.J and Meijers-Heijboer, H.E and Hogervorst, F.B.L and Goldgar, D.E and Buys, S and John, E.M and Miron, A and Southey, M and Daly, M.B and Harbst, K and Borg, A and Rantala, J and Barbany-Bustinza, G and Ehrencrona, H and Stenmark-Askmalm, M and Kaufman, B and Laitman, Y and Milgrom, R and Friedman, E and Domchek, S.M and Nathanson, K.L and Rebbeck, T.R and Johannsson, O.T and Couch, F.J and Wang, X and Fredericksen, Z and Cuaas, D and Moreno, V and Pientka, F.K and Depping, R and Caldes, T and Osorio, A and Benitez, J and Bueren, J and Heikkinen, T and ... and Onkologi och Patologi, MV and Lund University and Oncology and Pathology, MV and Lunds universitet
Breast Cancer Research, ISSN 1465-542X, 2011, Volume 13, Issue 2, pp. R40 - R40
Journal Article
by Blein, S and Bardel, C and Danjean, V and McGuffog, L and Healey, S and Barrowdale, D and Lee, A and Dennis, J and Kuchenbaecker, K.B and Soucy, P and Terry, M.B and Chung, W.K and Goldgar, D.E and Buys, S.S and Janavicius, R and Tihomirova, L and Tung, N and Dorfling, C.M and Rensburg, E.J. van and Neuhausen, S.L and Ding, Y.C and Gerdes, A.M and Ejlertsen, B and Nielsen, F.C and Hansen, T.V and Osorio, A and Benitez, J and Conejero, R.A and Segota, E and Weitzel, J.N and Thelander, M and Peterlongo, P and Radice, P and Pensotti, V and Dolcetti, R and Bonanni, B and Peissel, B and Zaffaroni, D and Scuvera, G and Manoukian, S and Varesco, L and Capone, G.L and Papi, L and Ottini, L and Yannoukakos, D and Konstantopoulou, I and Garber, J and Hamann, U and Donaldson, A and Brady, A and Brewer, C and Foo, C and Evans, D.G and Frost, D and Eccles, D and Douglas, F and Cook, J and Adlard, J and Barwell, J and Walker, L and Izatt, L and Side, L.E and Kennedy, M.J and Tischkowitz, M and Rogers, M.T and Porteous, M.E and Morrison, P.J and Platte, R and Eeles, R and Davidson, R and Hodgson, S and Cole, T and Godwin, A.K and Isaacs, C and Claes, K and Leeneer, K. De and Meindl, A and Gehrig, A and Wappenschmidt, B and Sutter, C and Engel, C and Niederacher, D and Steinemann, D and Plendl, H and Kast, K and Rhiem, K and Ditsch, N and Arnold, N and Varon-Mateeva, R and Schmutzler, R.K and Preisler-Adams, S and Markov, N.B and Wang-Gohrke, S and Pauw, A. de and Lefol, C and Lasset, C and Leroux, D and Rouleau, E and Damiola, F and yfus, H and ... and Oncology and Pathology, Kamprad Lab and Lund University and Lunds universitet and Onkologi och Patologi, Kampradlab
Breast Cancer Research, ISSN 1465-5411, 2015, Volume 17, Issue 1, p. 61
INTRODUCTION: Individuals carrying pathogenic mutations in the BRCA1 and BRCA2 genes have a high lifetime risk of breast cancer. BRCA1 and BRCA2 are involved... 
Clinical Medicine | Medical and Health Sciences | Klinisk medicin | Cancer and Oncology | Medicin och hälsovetenskap | Cancer och onkologi
Journal Article