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Trends in Pharmacological Sciences, ISSN 0165-6147, 2015, Volume 37, Issue 3, pp. 172 - 183
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2017, Volume 12, Issue 6, p. e0180116
Transient receptor potential cation channel subfamily V member 1 (TRPV1) are sensitive to heat, capsaicin, pungent chemicals and other noxious stimuli. They... 
Usage | Human genome | Nucleotide sequencing | Research | DNA sequencing
Journal Article
Molecular Pain, ISSN 1744-8069, 10/2011, Volume 7, Issue 1, pp. 78 - 78
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2013, Volume 8, Issue 12, pp. e81228 - e81228
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2016, Volume 113, Issue 44, pp. 12544 - 12549
Chemotherapy-induced peripheral neuropathic pain (CIPNP) is a severe dose- and therapy-limiting side effect of widely used cytostatics that is particularly... 
Oxidized lipids | Chemotherapy-induced neuropathy | TRPV1 | Neuropathic pain | Telmisartan | chemotherapy-induced neuropathy | ACTIVATION | telmisartan | MULTIDISCIPLINARY SCIENCES | SENSORY NEURONS | CHEMOTHERAPY | SOLUBLE EPOXIDE HYDROLASE | neuropathic pain | POTENTIAL VANILLOID 1 | IN-VITRO | METABOLISM | MECHANICAL HYPERALGESIA | INFLAMMATION | oxidized lipids | Gene Expression Regulation, Enzymologic - drug effects | Paclitaxel - pharmacology | Humans | Cytochrome P-450 Enzyme System - metabolism | Male | Angiotensin II Type 1 Receptor Blockers - pharmacology | Paclitaxel - toxicity | Neuralgia - prevention & control | HEK293 Cells | Neuralgia - chemically induced | Pain Threshold - drug effects | Female | Molecular Targeted Therapy - methods | Mice, Inbred C57BL | Linoleic Acids - metabolism | Antineoplastic Agents, Phytogenic - toxicity | Animals | Benzoates - pharmacology | Cytochrome P-450 Enzyme System - genetics | Benzimidazoles - pharmacology | Linoleic Acids - blood | Antineoplastic Agents, Phytogenic - pharmacology | Ganglia, Spinal - drug effects | Ganglia, Spinal - metabolism | Prevention | Complications and side effects | Paclitaxel | Causes of | Cytochromes | Peripheral nerve diseases | Health aspects | Protein expression | Chemotherapy | Side effects | Pain | Rodents | Index Medicus | Biological Sciences
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2014, Volume 9, Issue 4, pp. e93338 - e93338
Ultraviolet-B (UVB)-induced inflammation produces a dose-dependent mechanical and thermal hyperalgesia in both humans and rats, most likely via inflammatory... 
PERIPHERAL-NERVE INJURY | NEUROPATHIC PAIN | RNA-SEQ | MULTIDISCIPLINARY SCIENCES | IN-VIVO | GENE-EXPRESSION | HYPERALGESIA | CHEMOKINE | MODEL | PHYLOGENETIC TREES | SENSORY NEURONS | Inflammation - pathology | Rats, Wistar | Skin - metabolism | Humans | Up-Regulation - radiation effects | Genome - genetics | Transcription, Genetic - radiation effects | Male | Gene Expression Profiling | Lectins, C-Type - metabolism | Reference Standards | Ultraviolet Rays | Antigens, Neoplasm - metabolism | Biomarkers, Tumor - metabolism | Chemokine CCL2 - metabolism | Skin - pathology | Reproducibility of Results | Ganglia, Spinal - radiation effects | Up-Regulation - genetics | Pancreatitis-Associated Proteins | Animals | Sequence Analysis, RNA | Models, Biological | Skin - radiation effects | Ganglia, Spinal - pathology | Gene Expression Regulation - radiation effects | Inflammation - genetics | Ganglia, Spinal - metabolism | Genetic transcription | Nonsteroidal anti-inflammatory drugs | RNA | Health aspects | Analysis | Neurosciences | Correlation | Profiling | Transcription | Genes | Genomes | Interleukin 24 | Experiments | Interleukin 6 | Proteins | Keratin | Pain | Dorsal root ganglia | Rodents | CCL20 protein | Pain perception | Cytokines | U.V. radiation | Rats | CCL3 protein | Inflammation | Gene expression | Ribonucleic acid--RNA | Ganglia | Ultraviolet radiation | Irradiation | Ligands | Skin | Cyclooxygenase-2 | Molecular biology | Chemokines | Monocyte chemoattractant protein 1 | Index Medicus | Ribonucleic acid
Journal Article
Frontiers in Immunology, ISSN 1664-3224, 10/2018, Volume 9, pp. 2261 - 2261
Macrophages are highly versatile cells, which acquire, depending on their microenvironment, pro- (M1-like), or antiinflammatory (M2-like) phenotypes. Here, we... 
Polarization | Pain | Acute inflammation | Migration | G2A | GPCR | Macrophage | RECRUITMENT | acute inflammation | pain | IMMUNE CELLS | MONOCYTES | SUBSETS | SIGNALS | macrophage | NEUTROPHILS | IMMUNOLOGY | LYSOPHOSPHATIDYLCHOLINE | INFLAMMATION | migration | polarization | ACCUMULATION | Inflammation | Research | G proteins | Macrophages | Tissues | Health aspects | Cell migration
Journal Article
BBA - Molecular and Cell Biology of Lipids, ISSN 1388-1981, 07/2018, Volume 1863, Issue 7, pp. 669 - 678
Eicosanoids play a crucial role in inflammatory pain. However, there is very little knowledge about the contribution of oxidized linoleic acid metabolites in... 
TRPV1 | Oxidized linoleic acid metabolites (OLAMs) | Thermal hyperalgesia | sEH-inhibitor | Inflammatory pain | TPPU | EICOSANOIDS | BIOCHEMISTRY & MOLECULAR BIOLOGY | MECHANISMS | CELL BIOLOGY | SOLUBLE EPOXIDE HYDROLASE | HEAT | INHIBITION | BIOPHYSICS | GENE | NONSTEROIDAL ANTIINFLAMMATORY DRUGS | NSAIDS | FATTY-ACID | EPOXYEICOSATRIENOIC ACIDS | Inflammation - chemically induced | Analgesics - pharmacology | Freund's Adjuvant - toxicity | Linoleic Acid - metabolism | Humans | Male | Hyperalgesia - pathology | Oleic Acids - metabolism | Inflammation - complications | TRPV Cation Channels - metabolism | Piperidines - pharmacology | Pain - drug therapy | Protein Kinase C - metabolism | Oxidation-Reduction - drug effects | Pain - etiology | Behavior, Animal - drug effects | Female | Sensory Receptor Cells - metabolism | Disease Models, Animal | Analgesics - therapeutic use | Hot Temperature - adverse effects | Enzyme Inhibitors - pharmacology | Phenylurea Compounds - therapeutic use | Enzyme Inhibitors - therapeutic use | Pain - pathology | Animals | Hyperalgesia - drug therapy | Piperidines - therapeutic use | Hyperalgesia - etiology | Zymosan - toxicity | Mice | Phenylurea Compounds - pharmacology | Epoxide Hydrolases - metabolism | Epoxide Hydrolases - antagonists & inhibitors | Metabolites | Unsaturated fatty acids | Linoleic acids | Index Medicus
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 04/2017, Volume 292, Issue 15, pp. 6123 - 6134
Journal Article