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European Journal of Pharmacology, ISSN 0014-2999, 06/2012, Volume 684, Issue 1-3, pp. 1 - 7
Nausea and vomiting are among the most common and distressing consequences of cytotoxic chemotherapies. Nausea and vomiting can be acute (0-24 h) or delayed... 
Granisetron | receptor | Netupitant | 5-HT | Ondansetron | Palonosetron
Journal Article
Cancer Treatment Reviews, ISSN 0305-7372, 12/2015, Volume 41, Issue 10, p. 904
* Nausea and delayed emesis in patients undergoing chemotherapy remain a challenge. * Data show that combined 5-HT.sub.3 receptor antagonists (RAs) and... 
Medical research | Chemotherapy | Medicine, Experimental | Clinical trials | Nausea | Cancer
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 01/2014, Volume 722, Issue 1, pp. 26 - 37
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 06/2012, Volume 684, Issue 1-3, p. 1
Journal Article
Experimental neurology, ISSN 0014-4886, 01/2020, p. 113181
The human brain consumes more energy than any other organ in the body and it relies on an uninterrupted supply of energy in the form of adenosine triphosphate... 
Journal Article
Cell Metabolism, ISSN 1550-4131, 01/2012, Volume 15, Issue 1, pp. 110 - 121
Journal Article
Neurochemical Research, ISSN 0364-3190, 11/2019
Journal Article
Molecular cancer therapeutics, ISSN 1535-7163, 9/2018, Volume 17, Issue 9, pp. 1824 - 1832
The broadly active glutamine antagonist 6-diazo-5-oxo-L-norleucine (DON) has been studied for sixty years as a potential anticancer therapeutic. Clinical... 
prodrug | DON | glutaminase | cancer | glutamine
Journal Article
eLife, ISSN 2050-084X, 05/2014, Volume 3, Issue 3, p. e02523
Journal Article
Molecular Cancer Therapeutics, ISSN 1535-7163, 09/2018, Volume 17, Issue 9, pp. 1824 - 1832
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 06/2015, Volume 125, Issue 6, pp. 2293 - 2306
Glutaminase (GLS), which converts glutamine to glutamate, plays a key role in cancer cell metabolism, growth, and proliferation. GLS is being explored as a... 
CANCER-CELLS | MEDICINE, RESEARCH & EXPERIMENTAL | KIDNEY-TYPE GLUTAMINASE | PHOSPHATE-ACTIVATED GLUTAMINASE | MITOCHONDRIAL METABOLISM | AEROBIC GLYCOLYSIS | GROWTH | C-MYC | ACUTE MYELOID-LEUKEMIA | 2-HYDROXYGLUTARATE LEVELS | EXPRESSION | Neoplasm Transplantation | Humans | Gene Expression Regulation, Neoplastic | Mutation, Missense | Carcinoma, Hepatocellular - drug therapy | Heterografts | Cell Transformation, Neoplastic - genetics | Carcinoma, Hepatocellular - genetics | Liver Neoplasms, Experimental - genetics | Liver Neoplasms, Experimental - pathology | Sulfides - pharmacology | Thiadiazoles - pharmacology | Glutaminase - biosynthesis | Mice, Transgenic | Carcinoma, Hepatocellular - enzymology | Cell Transformation, Neoplastic - metabolism | Glutaminase - antagonists & inhibitors | Gene Expression Regulation, Enzymologic | Animals | Liver Neoplasms, Experimental - drug therapy | Carcinoma, Hepatocellular - pathology | Liver Neoplasms, Experimental - enzymology | Mice | Mice, Inbred BALB C | Cell Transformation, Neoplastic - pathology | Glutaminase - genetics | Amino Acid Substitution | Medical research | Enzymes | Colleges & universities | Grants | Glucose | Metabolism | Fatty acids | Proteins | Survival analysis | Cell growth | Software | Lymphomas | Tumorigenesis | Infrared imaging systems | Laboratory animals | Tumors | Cancer | Crystal structure | Index Medicus | Abridged Index Medicus | Oncology | Hepatology
Journal Article
Journal of Alzheimer's Disease, ISSN 1387-2877, 04/2019, Volume 68, Issue 3, pp. 939 - 945
Studies over the past two decades report significant reductions in brain N-acetylaspartyl glutamate (NAAG) levels in neurodegenerative diseases with associated... 
Neurological diseases | Brain | Animal models | Restoration | Neurodegenerative diseases | Cognitive ability | Carboxypeptidase | Inhibition | Glutamate carboxypeptidase | Alzheimer's disease | N-Acetylaspartylglutamic acid
Journal Article