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2012, First edition., Advances in pharmacology ( San Diego, Calif.), ISBN 0123979277, Volume 65
Web Resource
Pharmacological Research, ISSN 1043-6618, 08/2019, Volume 146, pp. 104291 - 104291
Journal Article
Journal of Investigative Dermatology, ISSN 0022-202X, 01/2010, Volume 130, Issue 1, pp. 28 - 37
Journal Article
Pharmacological Research, ISSN 1043-6618, 09/2018, Volume 135, pp. 265 - 267
Journal Article
Melanoma Management, ISSN 2045-0885, 05/2017, Volume 4, Issue 2, pp. 95 - 97
Dr Smalley earned his PhD in Pharmacology from the University of Cambridge, UK, in 2001. He worked as a post-doctoral fellow in the Oncology Department of... 
targeted therapy | immunotherapy | melanoma | BRAF
Journal Article
Cancer Discovery, ISSN 2159-8274, 02/2018, Volume 8, Issue 2, pp. 140 - 142
ERK inhibitors have enormous therapeutic potential against tumors that are BRAF mutant, BRAF-MEK inhibitor resistant, or RAS mutant. In this issue of Cancer... 
RESISTANCE | BRAF | MELANOMA | EVOLUTION | ONCOLOGY | Aminopyridines | Protein Kinase Inhibitors | Proto-Oncogene Proteins B-raf - genetics | Humans | Pyrroles | Cell Line, Tumor | Mutation | MAP Kinase Signaling System | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2008, Volume 105, Issue 8, pp. 3041 - 3046
Journal Article
Journal of Investigative Dermatology, ISSN 0022-202X, 01/2018, Volume 138, Issue 1, pp. 10 - 13
Cancer cells are highly plastic and adopt multiple phenotypic states that contribute to tumor progression. Heppt et al. demonstrate that the homeodomain... 
DRIVES | THERAPY | DERMATOLOGY | Melanoma - genetics | Humans | Gene Expression Regulation, Neoplastic | Transcription Factors | MSX1 Transcription Factor | Disease Progression | Neural Crest | Index Medicus
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 08/2010, Volume 363, Issue 9, pp. 876 - 878
Journal Article
Bioinformatics, ISSN 1367-4803, 2017, Volume 33, Issue 18, pp. 2951 - 2953
aSummary: Single-cell technologies allow characterization of transcriptomes and epigenomes for individual cells under different conditions and provide... 
VISUALIZATION | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | BIOCHEMICAL RESEARCH METHODS | MATHEMATICAL & COMPUTATIONAL BIOLOGY | Index Medicus | Applications Notes
Journal Article
Cancer Research, ISSN 0008-5472, 04/2011, Volume 71, Issue 7, pp. 2750 - 2760
This study addresses the role of PTEN loss in intrinsic resistance to the BRAF inhibitor PLX4720. Immunohistochemical staining of a tissue array covering all... 
METASTATIC MELANOMA | APOPTOSIS | PROTEIN | ONCOLOGY | PHOSPHORYLATION | CUTANEOUS MELANOMA | RAF KINASE | CANCER | MEDIATES RESISTANCE | LINES | ERK | RNA, Small Interfering - genetics | Up-Regulation | Humans | Drug Resistance, Neoplasm | Phosphatidylinositol 3-Kinases - metabolism | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Proto-Oncogene Proteins - biosynthesis | Bcl-2-Like Protein 11 | Melanoma - genetics | Apoptosis Regulatory Proteins - genetics | Indoles - pharmacology | Proto-Oncogene Proteins c-akt - metabolism | Proto-Oncogene Proteins B-raf - metabolism | Apoptosis Regulatory Proteins - biosynthesis | Melanoma - metabolism | Proto-Oncogene Proteins - antagonists & inhibitors | PTEN Phosphohydrolase - deficiency | Membrane Proteins - genetics | PTEN Phosphohydrolase - biosynthesis | Proto-Oncogene Proteins - genetics | Melanoma - pathology | Sulfonamides - pharmacology | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Membrane Proteins - biosynthesis | Membrane Proteins - antagonists & inhibitors | Proto-Oncogene Proteins B-raf - genetics | Melanoma - drug therapy | Apoptosis Regulatory Proteins - antagonists & inhibitors | Cell Line, Tumor | Protein Kinase Inhibitors - pharmacology | Apoptosis - physiology | Mutation | RNA, Small Interfering - administration & dosage | Index Medicus | PTEN | melanoma | BRAF | PLX4032 | therapy | resistance
Journal Article
eLife, ISSN 2050-084X, 01/2018, Volume 7
Harnessing female sex hormones may improve how all patients with melanoma respond to treatment. 
Female | Male | Humans | Melanoma | Skin Neoplasms | Women | Prognosis | Ipilimumab | Hormones, Sex | Skin | Risk factors | Skin cancer | Transcription factors | Research | Hormones | Cancer therapies | Proteins | Sex hormones | Medical prognosis | Immunotherapy | Females | Immune system | Tumors | Index Medicus
Journal Article
Genes and Cancer, ISSN 1947-6019, 2015, Volume 6, Issue 9-10, pp. 367 - 368
Journal Article
Journal Article
Nature Reviews Drug Discovery, ISSN 1474-1776, 06/2011, Volume 10, Issue 6, pp. 411 - 412
Journal Article