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The EMBO Journal, ISSN 0261-4189, 07/2013, Volume 32, Issue 13, pp. 1903 - 1916
The Wnt/β‐catenin signalling and autophagy pathways each play important roles during development, adult tissue homeostasis and tumorigenesis. Here we identify... 
cancer | autophagy | LC3 | p62 | Wnt/β‐catenin | Autophagy | Wnt/β-catenin | Cancer | CELLS | OXIDATIVE STRESS | BIOCHEMISTRY & MOLECULAR BIOLOGY | P62/SQSTM1 | CASPASE CLEAVAGE | SELECTIVE AUTOPHAGY | CELL BIOLOGY | TRANSCRIPTION FACTOR NRF2 | STRUCTURAL BASIS | COLORECTAL-CANCER | Wnt/beta-catenin | RNA, Small Interfering - genetics | Colonic Neoplasms - genetics | Microtubule-Associated Proteins - genetics | Microtubule-Associated Proteins - metabolism | Sequestosome-1 Protein | Humans | Wnt Proteins - metabolism | Antigens, CD - genetics | Colonic Neoplasms - metabolism | Immunoenzyme Techniques | Antigens, CD - metabolism | Lysosomes - metabolism | Wnt Proteins - genetics | Chromatin Immunoprecipitation | Proteolysis | Tumor Cells, Cultured | Real-Time Polymerase Chain Reaction | Recombinant Proteins - metabolism | Transcription Factor 4 | Leukocyte Immunoglobulin-like Receptor B1 | Phagosomes - metabolism | RNA, Messenger - genetics | Recombinant Proteins - genetics | Transcription Factors - genetics | Reverse Transcriptase Polymerase Chain Reaction | beta Catenin - metabolism | Blotting, Western | beta Catenin - genetics | Mice, Knockout | Transcription Factors - metabolism | Animals | beta Catenin - antagonists & inhibitors | Colonic Neoplasms - pathology | Adaptor Proteins, Signal Transducing - genetics | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - genetics | Fluorescent Antibody Technique | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - metabolism | Mice | Proteasome Endopeptidase Complex - metabolism | Adaptor Proteins, Signal Transducing - metabolism | Receptors, Immunologic - genetics | Receptors, Immunologic - metabolism | Index Medicus | β-catenin | Wnt
Journal Article
EMBO Journal, ISSN 0261-4189, 07/2013, Volume 32, Issue 13, p. 1903
  The Wnt/[beta]-catenin signalling and autophagy pathways each play important roles during development, adult tissue homeostasis and tumorigenesis. Here we... 
Signaling | Angiogenesis | Gene expression | Autophagy | Cancer
Journal Article
Journal Article
Gastroenterology, ISSN 0016-5085, 2005, Volume 128, Issue 4, pp. 1081 - 1088
Journal Article
Cancer Research, ISSN 0008-5472, 01/2010, Volume 70, Issue 2, pp. 609 - 620
Journal Article
ONCOGENE, ISSN 0950-9232, 05/2012, Volume 31, Issue 22, pp. 2761 - 2772
Understanding the mechanisms that promote aberrant tumour cell survival is critical for the determination of novel strategies to combat colorectal cancer... 
CANCER-CELLS | DNA-BINDING | TRANSCRIPTIONAL ACTIVATION | colorectal cancer | ONCOPROTEIN BCL-3 | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | RECEPTOR | ALTERNATIVE TRANSLATION INITIATION | BAG-1 | EGFR | CELL BIOLOGY | NF-kappa B | ONCOLOGY | GENETICS & HEREDITY | SQUAMOUS-CELL CARCINOMA | COX2 | EXPRESSION | p50 homodimers | RNA, Small Interfering - genetics | Receptor, Epidermal Growth Factor - genetics | Cell Proliferation | Immunoprecipitation | Luciferases - metabolism | Embryo, Mammalian | Colorectal Neoplasms - genetics | Humans | Protein Multimerization | Gene Expression Regulation, Neoplastic | NF-kappa B p50 Subunit - genetics | Immunoenzyme Techniques | DNA-Binding Proteins - metabolism | Receptor, Epidermal Growth Factor - metabolism | Transfection | Chromatin Immunoprecipitation | Cyclooxygenase 2 - genetics | Fibroblasts | Electrophoretic Mobility Shift Assay | Real-Time Polymerase Chain Reaction | Colorectal Neoplasms - metabolism | Promoter Regions, Genetic | NF-kappa B - antagonists & inhibitors | NF-kappa B p50 Subunit - metabolism | RNA, Messenger - genetics | Cells, Cultured | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Mice, Knockout | Transcription Factors - metabolism | Animals | Cyclooxygenase 2 - metabolism | NF-kappa B - physiology | Mice | Cell Transformation, Neoplastic - pathology | Colorectal Neoplasms - pathology | Apoptosis | Index Medicus | Phosphorylation | Cell survival | Epidermal growth factor receptors | Transcription | Colorectal cancer | Data processing | Embryo fibroblasts | Regulatory sequences | siRNA | Adenoma | Gene expression | Carcinogenesis | Metastases | NF- Kappa B protein | Microenvironments | Cyclooxygenase-2
Journal Article
01/2008, ISBN 0549950419
Pulmonary fibrosis involves the invasion of lung tissue with fibrotic, scar tissue and affects roughly five million people total worldwide. Fibrotic... 
Toxicology | Environmental science
Dissertation
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