Articles

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (45) 45
humans (31) 31
schizophrenia (22) 22
male (21) 21
female (16) 16
adult (14) 14
bipolar disorder (14) 14
genome-wide association (13) 13
genomes (13) 13
hematology (12) 12
middle aged (12) 12
neurosciences (12) 12
oncology (12) 12
mental disorders (11) 11
risk (11) 11
risk factors (11) 11
genetic predisposition to disease (10) 10
pleiotropy (9) 9
psychiatry (9) 9
research (9) 9
schizophrenia - genetics (9) 9
aged (8) 8
article (8) 8
biochemistry & molecular biology (8) 8
genome-wide association study (8) 8
polymorphism, single nucleotide (8) 8
prognosis (8) 8
animals (7) 7
loci (7) 7
medical and health sciences (7) 7
medicin och hälsovetenskap (7) 7
metaanalysis (7) 7
mice (7) 7
adolescent (6) 6
analysis (6) 6
cancer (6) 6
disease (6) 6
gene expression (6) 6
gene loci (6) 6
heritability (6) 6
multidisciplinary sciences (6) 6
psychosis (6) 6
young adult (6) 6
consortia (5) 5
genetic aspects (5) 5
genetic variance (5) 5
genetics (5) 5
genetics & heredity (5) 5
genomics (5) 5
gwas (5) 5
polygenic inheritance (5) 5
rat-brain (5) 5
survival (5) 5
abridged index medicus (4) 4
antineoplastic combined chemotherapy protocols - therapeutic use (4) 4
basic medicine (4) 4
brain (4) 4
chemotherapy (4) 4
cognitive ability (4) 4
common variants (4) 4
conditional survival (4) 4
educational attainment (4) 4
flow cytometry (4) 4
genes (4) 4
genetic factors (4) 4
genetic variation (4) 4
genome-wide association study - methods (4) 4
genotype (4) 4
glucose - metabolism (4) 4
immunology (4) 4
lymphoma survivors (4) 4
magnetic resonance spectroscopy (4) 4
medical genetics (4) 4
medicinsk genetik (4) 4
medicinska och farmaceutiska grundvetenskaper (4) 4
non-hodgkin-lymphoma (4) 4
norway - epidemiology (4) 4
phenotypes (4) 4
risk loci (4) 4
single-nucleotide polymorphism (4) 4
studies (4) 4
5-factor model (3) 3
aged, 80 and over (3) 3
alzheimer's disease (3) 3
anthracyclines (3) 3
association (3) 3
autologous stem cell transplantation (3) 3
brain - metabolism (3) 3
breast-cancer (3) 3
care and treatment (3) 3
chromatography, high pressure liquid (3) 3
clinical medicine (3) 3
clinical neurology (3) 3
epilepsy (3) 3
etiology (3) 3
expression (3) 3
follow-up studies (3) 3
gaba (3) 3
gene (3) 3
genetic analysis (3) 3
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text Genome-wide analyses for personality traits identify six genomic loci and show correlations with psychiatric disorders
by Lo, Min-Tzu and Hinds, David A and Tung, Joyce Y and Franz, Carol and Fan, Chun-Chieh and Wang, Yunpeng and Smeland, Olav B and Schork, Andrew and Holland, Dominic and Kauppi, Karolina and Sanyal, Nilotpal and Escott-Price, Valentina and Smith, Daniel J and O'Donovan, Michael and Stefansson, Hreinn and Bjornsdottir, Gyda and Thorgeirsson, Thorgeir E and Stefansson, Kari and McEvoy, Linda K and Dale, Anders M and Andreassen, Ole A and Chen, Chi-Hua and Medicinska fakulteten and Umeå universitet and Institutionen för strålningsvetenskaper
Nature Genetics, ISSN 1061-4036, 01/2017, Volume 49, Issue 1, pp. 152 - 156
Personality is influenced by genetic and environmental factors(1) and associated with mental health. However, the underlying genetic determinants are largely... 
TEMPERAMENT | METAANALYSIS | PERFORMANCE | GENETICS & HEREDITY | SCHIZOPHRENIA | NEUROTICISM | BIPOLAR DISORDER | 5-FACTOR MODEL | ASSOCIATION | HERITABILITY | Genetic Predisposition to Disease | Genome-Wide Association Study | Meta-Analysis as Topic | Prospective Studies | Humans | Middle Aged | Genetic Loci - genetics | Male | Personality - genetics | Mental Disorders - genetics | Genetic Markers - genetics | Adult | Female | Aged | Polymorphism, Single Nucleotide | Genome-wide association studies | Genetic variation | Mental illness | Analysis | Mental health | Schizophrenia | Bipolar disorder | Principal components analysis | Personality | Genomes | Research | Behavior disorders | Cell adhesion & migration | Meta-analysis | Studies | Consortia | Personality traits | Genetics | Index Medicus | Clinical Medicine | Basic Medicine | Medical Genetics | Medicinsk genetik | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Psykiatri | Klinisk medicin | Psychiatry
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence
by Savage, Jeanne E and Jansen, Philip R and Stringer, Sven and Watanabe, Kyoko and Bryois, Julien and De Leeuw, Christiaan A and Nagel, Mats and Awasthi, Swapnil and Barr, Peter B and Coleman, Jonathan R. I and Grasby, Katrina L and Hammerschlag, Anke R and Kaminski, Jakob A and Karlsson, Robert and Krapohl, Eva and Lam, Max and Nygaard, Marianne and Reynolds, Chandra A and Trampush, Joey W and Young, Hannah and Zabaneh, Delilah and Hägg, Sara and Hansell, Narelle K and Karlsson, Ida K and Linnarsson, Sten and Montgomery, Grant W and Muñoz-Manchado, Ana B and Quinlan, Erin B and Schumann, Gunter and Skene, Nathan G and Webb, Bradley T and White, Tonya and Arking, Dan E and Avramopoulos, Dimitrios and Bilder, Robert M and Bitsios, Panos and Burdick, Katherine E and Cannon, Tyrone D and Chiba-Falek, Ornit and Christoforou, Andrea and Cirulli, Elizabeth T and Congdon, Eliza and Corvin, Aiden and Davies, Gail and Deary, Ian J and Derosse, Pamela and Dickinson, Dwight and Djurovic, Srdjan and Donohoe, Gary and Conley, Emily Drabant and Eriksson, Johan G and Espeseth, Thomas and Freimer, Nelson A and Giakoumaki, Stella and Giegling, Ina and Gill, Michael and Glahn, David C and Hariri, Ahmad R and Hatzimanolis, Alex and Keller, Matthew C and Knowles, Emma and Koltai, Deborah and Konte, Bettina and Lahti, Jari and Le Hellard, Stephanie and Lencz, Todd and Liewald, David C and London, Edythe and Lundervold, Astri J and Malhotra, Anil K and Melle, Ingrid and Morris, Derek and Need, Anna C and Ollier, William and Palotie, Aarno and Payton, Antony and Pendleton, Neil and Poldrack, Russell A and Räikkönen, Katri and Reinvang, Ivar and Roussos, Panos and Rujescu, Dan and Sabb, Fred W and Scult, Matthew A and Smeland, Olav B and Smyrnis, Nikolaos and Starr, John M and Steen, Vidar M and Stefanis, Nikos C and Straub, Richard E and Sundet, Kjetil and Tiemeier, Henning and Voineskos, Aristotle N and Weinberger, Daniel R and Widen, Elisabeth and Yu, Jin and Abecasis, Goncalo and Andreassen, Ole A and Breen, Gerome and Christiansen, Lene and ...
Nature Genetics, ISSN 1061-4036, 07/2018, Volume 50, Issue 7, pp. 912 - 919
Intelligence is highly heritable(1) and a major determinant of human health and well-being(2). Recent genome-wide meta-analyses have identified 24 genomic loci... 
GENERAL COGNITIVE FUNCTION | CONSORTIUM | TEST BATTERIES | GWAS | ANNOTATION | GENETICS & HEREDITY | RISK | LOCI | EDUCATIONAL-ATTAINMENT | TRAITS | HERITABILITY | Brain | Chromatin | Neurosciences | Intelligence | Synaptogenesis | Mental disorders | Genomics | Genes | Cognitive ability | Schizophrenia | Association analysis | Nervous system | Identification | Mapping | Genomes | Genetic effects | Annotations | Coding | Genetic analysis | Neostriatum | Alzheimer's disease | Bioinformatics | Neurodegenerative diseases | Neurons | Attention deficit hyperactivity disorder | Causation | Gene expression | Spiny neurons | Loci | Educational attainment | Meta-analysis | Quantitative trait loci | Neurological diseases | Studies | Pyramidal cells | Gene loci | Gene mapping | Alzheimers disease | Hippocampus | Index Medicus | Medical and Health Sciences | Medicin och hälsovetenskap | Alzheimer disease | Article | nervous system development | genetic association | gene location | schizophrenia | Klinisk medicin | pleiotropy | gene mapping | genetic correlation | priority journal | human | Neurologi | corpus striatum | hippocampus | synapse | chromatin | heredity | genetic variability | intelligence | pyramidal nerve cell | gene locus | Mendelian randomization analysis | Clinical Medicine | Neurology | expression quantitative trait locus | medium spiny neuron | genome-wide association study | attention deficit disorder | exon | conserved sequence | gene expression
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text Bivariate causal mixture model quantifies polygenic overlap between complex traits beyond genetic correlation
by Frei, Oleksandr and Holland, Dominic and Smeland, Olav B and Shadrin, Alexey A and Fan, Chun Chieh and Maeland, Steffen and O’Connell, Kevin S and Wang, Yunpeng and Djurovic, Srdjan and Thompson, Wesley K and Andreassen, Ole A and Dale, Anders M
Nature Communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 2417 - 11
Accumulating evidence from genome wide association studies (GWAS) suggests an abundance of shared genetic influences among complex human traits and disorders,... 
Phenotypes | Bivariate analysis | Statistical analysis | Mental disorders | Schizophrenia | Bipolar disorder | Genomes | Single-nucleotide polymorphism | Educational attainment | Education | Venn diagrams | Influence | Heritability | Polygenic inheritance | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text The emerging pattern of shared polygenic architecture of psychiatric disorders, conceptual and methodological challenges
by Smeland, Olav B and Frei, Oleksandr and Fan, Chun-Chieh and Shadrin, Alexey and Dale, Anders M and Andreassen, Ole A
Psychiatric Genetics, ISSN 0955-8829, 10/2019, Volume 29, Issue 5, pp. 152 - 159
Genome-wide association studies have transformed psychiatric genetics and provided novel insights into the genetic etiology of psychiatric disorders. Two major... 
Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text Triheptanoin partially restores levels of tricarboxylic acid cycle intermediates in the mouse pilocarpine model of epilepsy
by Hadera, Mussie G and Smeland, Olav B and McDonald, Tanya S and Tan, Kah Ni and Sonnewald, Ursula and Borges, Karin
Journal of Neurochemistry, ISSN 0022-3042, 04/2014, Volume 129, Issue 1, pp. 107 - 119
Triheptanoin, the triglyceride of heptanoate, is anticonvulsant in various epilepsy models. It is thought to improve energy metabolism in the epileptic brain... 
status epilepticus | NMR | C isotope | spectroscopy | anaplerosis | medium chain triglyceride | seizures | NMR spectroscopy | Citric Acid Cycle - drug effects | Epilepsy - metabolism | Male | Pilocarpine - toxicity | Hippocampus - drug effects | Random Allocation | Cerebral Cortex - metabolism | Triglycerides - administration & dosage | Hippocampus - metabolism | Animals | Epilepsy - chemically induced | Epilepsy - drug therapy | Citric Acid Cycle - physiology | Mice | Cerebral Cortex - drug effects | Disease Models, Animal | Neurochemistry | Pharmacology | Epilepsy | Rodents | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text Identification of shared genetic variants between schizophrenia and lung cancer
by Zuber, Verena and Jönsson, Erik G and Frei, Oleksandr and Witoelar, Aree and Thompson, Wesley K and Schork, Andrew J and Bettella, Francesco and Wang, Yunpeng and Djurovic, Srdjan and Smeland, Olav B and Dieset, Ingrid and Fanous, Ayman H and Desikan, Rahul S and Küry, Sébastien and Bézieau, Stéphane and Dale, Anders M and Mills, Ian G and Andreassen, Ole A
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 674 - 8
Epidemiology studies suggest associations between schizophrenia and cancer. However, the underlying genetic mechanisms are not well understood, and difficult... 
RISK LOCI | METAANALYSIS | MULTIDISCIPLINARY SCIENCES | DISEASE | SUSCEPTIBILITY LOCI | DISORDERS | PLEIOTROPY | COMPLEX TRAITS | EXPRESSION | INVERSE | GENOME-WIDE ASSOCIATION | Lung Neoplasms - genetics | Genetic Predisposition to Disease | Schizophrenia - genetics | Epigenesis, Genetic | Humans | Female | Male | Polymorphism, Single Nucleotide | Genome-Wide Association Study - methods | Multifactorial Inheritance | Receptors, Nicotinic - genetics | Mental disorders | Lung | Lung cancer | Schizophrenia | Genomes | Gene expression | Epidemiology | Genetic variance | Major histocompatibility complex | Colon cancer | Genetic analysis | Rectum | Epigenetics | Acetylcholine receptors (nicotinic) | Acetylcholine | Gene loci | Genetic factors | Colon | Histocompatibility | Prostate | Prostate cancer | Smoking | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text Genome-wide analysis reveals extensive genetic overlap between schizophrenia, bipolar disorder, and intelligence
by Smeland, Olav B and Bahrami, Shahram and Frei, Oleksandr and Shadrin, Alexey and O’Connell, Kevin and Savage, Jeanne and Watanabe, Kyoko and Krull, Florian and Bettella, Francesco and Steen, Nils Eiel and Ueland, Torill and Posthuma, Danielle and Djurovic, Srdjan and Dale, Anders M and Andreassen, Ole A
Molecular Psychiatry, ISSN 1359-4184, 2019
Schizophrenia (SCZ) and bipolar disorder (BD) are severe mental disorders associated with cognitive impairment, which is considered a major determinant of... 
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text Discovery of shared genomic loci using the conditional false discovery rate approach
by Smeland, Olav B and Frei, Oleksandr and Shadrin, Alexey and O'Connell, Kevin and Fan, Chun-Chieh and Bahrami, Shahram and Holland, Dominic and Djurovic, Srdjan and Thompson, Wesley K and Dale, Anders M and Andreassen, Ole A
Human genetics, ISSN 0340-6717, 09/2019, pp. 1 - 10
In recent years, genome-wide association study (GWAS) sample sizes have become larger, the statistical power has improved and thousands of trait-associated... 
Neurological diseases | Phenotypes | Etiology | Cognitive ability | Single-nucleotide polymorphism | Gene loci | Genomes | Statistics | Bayesian analysis | Polygenic inheritance | Genetic relationship
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text Genome-wide association study identifies 30 loci associated with bipolar disorder
by Stahl, Eli A and Breen, Gerome and Forstner, Andreas J and McQuillin, Andrew and Ripke, Stephan and Trubetskoy, Vassily and Mattheisen, Manuel and Wang, Yunpeng and Coleman, Jonathan R. I and Gaspar, Héléna A and de Leeuw, Christiaan A and Steinberg, Stacy and Pavlides, Jennifer M. Whitehead and Trzaskowski, Maciej and Byrne, Enda M and Pers, Tune H and Holmans, Peter A and Richards, Alexander L and Abbott, Liam and Agerbo, Esben and Akil, Huda and Albani, Diego and Alliey-Rodriguez, Ney and Als, Thomas D and Anjorin, Adebayo and Antilla, Verneri and Awasthi, Swapnil and Badner, Judith A and Bækvad-Hansen, Marie and Barchas, Jack D and Bass, Nicholas and Bauer, Michael and Belliveau, Richard and Bergen, Sarah E and Pedersen, Carsten Bøcker and Bøen, Erlend and Boks, Marco P and Boocock, James and Budde, Monika and Bunney, William and Burmeister, Margit and Bybjerg-Grauholm, Jonas and Byerley, William and Casas, Miquel and Cerrato, Felecia and Cervantes, Pablo and Chambert, Kimberly and Charney, Alexander W and Chen, Danfeng and Churchhouse, Claire and Clarke, Toni-Kim and Coryell, William and Craig, David W and Cruceanu, Cristiana and Curtis, David and Czerski, Piotr M and Dale, Anders M and de Jong, Simone and Degenhardt, Franziska and Del-Favero, Jurgen and DePaulo, J. Raymond and Djurovic, Srdjan and Dobbyn, Amanda L and Dumont, Ashley and Elvsåshagen, Torbjørn and Escott-Price, Valentina and Fan, Chun Chieh and Fischer, Sascha B and Flickinger, Matthew and Foroud, Tatiana M and Forty, Liz and Frank, Josef and Fraser, Christine and Freimer, Nelson B and Frisén, Louise and Gade, Katrin and Gage, Diane and Garnham, Julie and Giambartolomei, Claudia and Pedersen, Marianne Giørtz and Goldstein, Jaqueline and Gordon, Scott D and Gordon-Smith, Katherine and Green, Elaine K and Green, Melissa J and Greenwood, Tiffany A and Grove, Jakob and Guan, Weihua and Guzman-Parra, José and Hamshere, Marian L and Hautzinger, Martin and Heilbronner, Urs and Herms, Stefan and Hipolito, Maria and Hoffmann, Per and Holland, Dominic and Huckins, Laura and Jamain, Stéphane and Johnson, Jessica S and Juréus, Anders and ... and Bipolar Disorder Working Grp Psych and eQTLGen Consortium and BIOS Consortium and Bipolar Disorder Working Group of the Psychiatric Genomics Consortium and the Bipolar Disorder Working Group of the Psychiatric Genomics Consortium
Nature Genetics, ISSN 1061-4036, 05/2019, Volume 51, Issue 5, pp. 793 - 803
Bipolar disorder is a highly heritable psychiatric disorder. We performed a genome-wide association study (GWAS) including 20,352 cases and 31,358 controls of... 
INDIVIDUALS | GWAS | METAANALYSIS | VARIANTS | GENES | GENETICS & HEREDITY | SCHIZOPHRENIA | RISK | LD SCORE REGRESSION | HERITABILITY | POLYGENICITY | Quantitative trait loci | Genome-wide association studies | Usage | Bipolar disorder | Genetic aspects | Identification and classification | Health aspects | Risk factors | Neurosciences | Genealogy | Working groups | Mental disorders | Secretion | Genomics | Neurobiology | Schizophrenia | Genomes | Mental depression | Gene expression | Insulin | Loci | Datasets | Psychosis | Studies | Consortia | Heterogeneity | Liability | Genetic analysis | Ion channels | Alzheimers disease
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
10. Full Text Brain Mitochondrial Metabolic Dysfunction and Glutamate Level Reduction in the Pilocarpine Model of Temporal Lobe Epilepsy in Mice
by Smeland, Olav B and Hadera, Mussie G and McDonald, Tanya S and Sonnewald, Ursula and Borges, Karin
Journal of Cerebral Blood Flow & Metabolism, ISSN 0271-678X, 7/2013, Volume 33, Issue 7, pp. 1090 - 1097
Although certain metabolic characteristics such as interictal glucose hypometabolism are well established for temporal lobe epilepsy (TLE), its pathogenesis... 
13C isotope | temporal lobe epilepsy | NMR spectroscopy | mitochondria | neurometabolism | glutamate | HIPPOCAMPAL EPILEPSY | CHRONIC PHASE | C-13 isotope | MAGNETIC-RESONANCE SPECTROSCOPY | EPILEPTOGENESIS | ASTROCYTES | NEUROSCIENCES | EXTRACELLULAR GLUTAMATE | GLUCOSE-METABOLISM | SEIZURE | ENDOCRINOLOGY & METABOLISM | SYNTHETASE | RAT-BRAIN | HEMATOLOGY | Gas Chromatography-Mass Spectrometry | Magnetic Resonance Spectroscopy | Epilepsy, Temporal Lobe - chemically induced | Neurotransmitter Agents - metabolism | Male | Epilepsy, Temporal Lobe - metabolism | Mitochondria - metabolism | Chromatography, High Pressure Liquid | Mice, Inbred Strains | Brain - metabolism | Amino Acids - metabolism | Animals | Pilocarpine - pharmacology | Glucose - metabolism | Glutamic Acid - metabolism | Mice | Disease Models, Animal | Index Medicus | Original
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
11. Full Text Identification of Genetic Loci Jointly Influencing Schizophrenia Risk and the Cognitive Traits of Verbal-Numerical Reasoning, Reaction Time, and General Cognitive Function
by Smeland, Olav B and Frei, Oleksandr and Kauppi, Karolina and Hill, W. David and Li, Wen and Wang, Yunpeng and Krull, Florian and Bettella, Francesco and Eriksen, Jon A and Witoelar, Aree and Davies, Gail and Fan, Chun C and Thompson, Wesley K and Lam, Max and Lencz, Todd and Chen, Chi-Hua and Ueland, Torill and Jönsson, Erik G and Djurovic, Srdjan and Deary, Ian J and Dale, Anders M and Andreassen, Ole A and NeuroCHARGE Cohorts Heart & Aging and NeuroCHARGE (Cohorts for Heart and Aging Research in Genomic Epidemiology) Cognitive Working Group and for the NeuroCHARGE (Cohorts for Heart and Aging Research in Genomic Epidemiology) Cognitive Working Group and Medicinska fakulteten and Umeå universitet and Institutionen för strålningsvetenskaper
JAMA Psychiatry, ISSN 2168-622X, 10/2017, Volume 74, Issue 10, pp. 1065 - 1075
IMPORTANCE: Schizophrenia is associated with widespread cognitive impairments. Although cognitive deficits are one of the factors most strongly associated with... 
CONSORTIUM | METAANALYSIS | PSYCHIATRY | NEUROCOGNITIVE DEFICITS | PSYCHOSIS | DISEASE | PLEIOTROPY | UK BIOBANK N=112151 | BIPOLAR DISORDER | GENOME-WIDE ASSOCIATION | POLYGENIC RISK | Genome-Wide Association Study | Quantitative Trait, Heritable | Humans | Male | Reaction Time | Schizophrenia - complications | Genetic Loci | Cognitive Dysfunction - etiology | Linkage Disequilibrium | Genetic Variation | Schizophrenia - genetics | Schizophrenia - diagnosis | Cognition - physiology | Adult | Cognitive Dysfunction - genetics | Female | Cognitive Dysfunction - diagnosis | Polymorphism, Single Nucleotide | alpha Catenin - genetics | GTPase-Activating Proteins - genetics | Schizophrenia | Genetic aspects | Research | Gene expression | Risk factors | Index Medicus | Abridged Index Medicus | Online First | Original Investigation | Clinical Medicine | Psykiatri | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap | Psychiatry
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights