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Nature Biotechnology, ISSN 1087-0156, 12/2018, Volume 36, Issue 12, pp. 1197 - 1202
Full-length RNA sequencing (RNA-Seq) has been applied to bulk tissue, cell lines and sorted cells to characterize transcriptomes(1)(-11), but applying this... 
HUMAN GENOME | MESSENGER-RNA | TRANSCRIPTOME | MECHANISM | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | ANNOTATION | DIVERSITY | EXPRESSION | SEQ | RNA sequencing | Genomes | Messenger RNA | Research | Analysis | Brain diseases | Cerebellum | Flow cytometry | Splicing | Astrocytes | Granule cells | Fluorescence | Tissues | Microglia | Gene sequencing | Confidence intervals | Annotations | Ribonucleic acids | Cell lines | Isoforms
Journal Article
The EMBO Journal, ISSN 0261-4189, 09/2019, Volume 38, Issue 17, pp. e101289 - n/a
Synapse development requires spatiotemporally regulated recruitment of synaptic proteins. In this study, we describe a novel presynaptic mechanism of cis... 
SALM | synapse organization | synaptogenesis | PIP | neurexin | BIOCHEMISTRY & MOLECULAR BIOLOGY | ADHESION-LIKE MOLECULES | CASK | DIMERIZATION | CELL-ADHESION | SYNCAM | FAMILY | CELL BIOLOGY | SALM1 | INTERACTS | DIFFERENTIATION | NEUROLIGIN-1 | EXPRESSION | PIP2 | Barrels | Depletion | Oligomerization | Synaptogenesis | Synaptic transmission | Neurons | Actin | Phosphatidylinositol 4,5-diphosphate | Clustering | Adhesion | Hippocampus | Index Medicus
Journal Article
PROTEOMICS, ISSN 1615-9853, 05/2019, Volume 19, Issue 9, pp. e1900027 - n/a
A simple and fast immunoprecipitation (IP) protocol is designed with the sample preparation incorporated, applicable to both low and high throughput. This new... 
magnetic beads | 96‐well plate | proteomics | sample preparation | immunoprecipitation | BIOCHEMISTRY & MOLECULAR BIOLOGY | 96-well plate | BIOCHEMICAL RESEARCH METHODS | ARCHITECTURE | PROTEIN COMPLEX | Proteomics | Proteins | Economic analysis | Immunoprecipitation | Sample preparation | Incubation | Antibodies | Protein A | Beads
Journal Article
The Journal of neuroscience : the official journal of the Society for Neuroscience, ISSN 0270-6474, 09/2017, Volume 37, Issue 39, pp. 9361 - 9379
Journal Article
Molecular Psychiatry, ISSN 1359-4184, 2019
An enigma in studies of neuropsychiatric disorders is how to translate polygenic risk into disease biology. For schizophrenia, where > 145 significant GWAS... 
Journal Article
Proteomics, ISSN 1615-9853, 10/2016, Volume 16, Issue 20, p. NA
DOI: 10.1002/pmic.201500400Type 1‐metabotropic glutamate receptors in the brain control long term synaptic plasticity and are considered important drug targets... 
Glutamate | Brain | Autism | Receptors | Plasticity (synaptic) | Rodents | Proteomics | Glutamic acid receptors | Glutamic acid receptors (metabotropic)
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 06/2012, Volume 109, Issue 23, pp. 9173 - 9178
Journal Article
Behavioural Brain Research, ISSN 0166-4328, 11/2015, Volume 294, p. 123
Behavioral tests of animals in a controlled experimental setting provide a valuable tool to advance understanding of genotype-phenotype relations, and to study... 
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 11/2015, Volume 211, Issue 3, p. 569
  Synaptic plasticity requires remodeling of the actin cytoskeleton. Although two actin isoforms, β- and ...actin, are expressed in dendritic spines, the... 
Neuroplasticity | Cellular proteins | Genetic aspects | Hippocampus (Brain) | Properties | Ligases | Cytoskeleton | Protein expression | Cellular biology | Rodents
Journal Article
Frontiers in Molecular Neuroscience, ISSN 1662-5099, 10/2018, Volume 11, pp. 364 - 364
Key to the human brain's unique capacities are a myriad of neural cell types, specialized molecular expression signatures, and complex patterns of neuronal... 
Neuroplasticity | SWATH-MS | Synapse | Species | Hippocampus | Proteomics | AMPA RECEPTOR COMPLEXES | NEUROTRANSMISSION | ENVIRONMENTS | hippocampus | proteomics | QUANTIFICATION | synapse | CHIMPANZEE BRAINS | NEUROSCIENCES | FAMILY | EVOLUTION | species | GENE-EXPRESSION | POSTSYNAPTIC DENSITY | neuroplasticity | REVEALS | Proteins | Primates | Comparative analysis
Journal Article
Addiction Biology, ISSN 1355-6215, 2018
Major depression and alcohol-related disorders frequently co-occur. Depression severity weighs on the magnitude and persistence of comorbid alcohol use... 
depression susceptibility | depression resilience | comorbidity
Journal Article