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1. Full Text Development and validation of a risk score for chronic kidney disease in HIV infection using prospective cohort data from the D:A:D study
by Mocroft, Amanda and Lundgren, Jens D and Ross, Michael and Law, Matthew and Reiss, Peter and Kirk, Ole and Smith, Colette and Wentworth, Deborah and Neuhaus, Jacqueline and Fux, Christoph A and Moranne, Olivier and Morlat, Phillipe and Johnson, Margaret A and Ryom, Lene and Lundgren, J. D and Powderly, B and Shortman, N and Moecklinghoff, C and Reilly, G and Franquet, X and Sabin, C. A and Phillips, A and Kirk, O and Weber, R and Pradier, C and Law, M and d'Arminio Monforte, A and Dabis, F and El-Sa, W. M and de Wit, S and Ryom, L and Kamara, D and Smith, C and Mocroft, A and Tverland, J and Mansfeld, M and Nielsen, J and Raben, D and Salbøl Brandt, R and Rickenbach, M and Fanti, I and Krum, E and Hillebregt, M and Geffard, S and Sundström, A and Delforge, M and Fontas, E and Torres, F and McManus, H and Wright, S and Kjær, J and Sjøl, A and Meidahl, P and Helweg-Larsen, J and Schmidt Iversen, J and Ross, M and Fux, C. A and Morlat, P and Moranne, O and Kesselring, A. M and Kamara, D. A and Friis-Møller, N and Kowalska, J and Sabin, C and Bruyand, M and Bower, M and Fätkenheuer, G and Donald, A and Grulich, A and Prins, J. M and Kuijpers, T. W and Scherpbier, H. J and van der Meer, J. T. M and Wit, F. W. M. N and Godfried, M. H and van der Poll, T and Nellen, F. J. B and Geerlings, S. E and van Vugt, M and Pajkrt, D and Bos, J. C and Wiersinga, W. J and van der Valk, M and Goorhuis, A and Hovius, J. W and van Eden, J and Henderiks, A and van Hes, A. M. H and Mutschelknauss, M and Nobel, H. E and Pijnappel, F. J. J and Westerman, A. M and Jurriaans, S and Back, N. K. T and Zaaijer, H. L and Berkhout, B and Cornelissen, M. T. E and Schinkel, C. J and Thomas, X. V and de Ruyter Ziekenhuis, Admiraal and ... and Royal Free Hosp Clin Cohort and INSIGHT Study Grp and DAD Study Grp and SMART Study Grp and ESPRIT Study Grp and D:A:D study group and Royal Free Hospital Clinic Cohort and SMART study group and INSIGHT study group and ESPRIT study group and D:A:D study group, the Royal Free Hospital Clinic Cohort, and the INSIGHT, SMART, and ESPRIT study groups
PLoS medicine, ISSN 1549-1277, 2015, Volume 12, Issue 3, pp. e1001809 - e1001809
Chronic kidney disease (CKD) is a major health issue for HIV-positive individuals, associated with increased morbidity and mortality. Development and... 
INDIVIDUALS | GLOMERULAR-FILTRATION-RATE | MEDICINE, GENERAL & INTERNAL | POSITIVE PERSONS | PROTEINURIA | ANTIRETROVIRAL THERAPY | ASSOCIATION | STAGE RENAL-DISEASE | LIFE EXPECTANCY | EXPOSURE | PREDICTION | Kidney - drug effects | Prospective Studies | Age Factors | Kidney - pathology | Renal Insufficiency, Chronic - etiology | Risk Assessment | Comorbidity | HIV Seropositivity - complications | Anti-HIV Agents - adverse effects | Humans | Middle Aged | Male | Risk | CD4 Lymphocyte Count | Incidence | Renal Insufficiency, Chronic - epidemiology | HIV | Clinical Decision-Making | HIV Infections - complications | Sex Factors | Adult | Anti-HIV Agents - therapeutic use | Female | HIV Infections - drug therapy | Index Medicus | Life Sciences | Human health and pathology | Santé publique et épidémiologie | Infectious diseases | Urology and Nephrology | Hypertension | Antiretroviral drugs | Mortality | Cardiovascular disease | Infections | Studies | Hepatitis | Data collection | Human immunodeficiency virus | Diabetes | Kidney diseases | Drug use
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2. Full Text Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma
by Chambers, John C and Zhang, Weihua and Sehmi, Joban and Li, Xinzhong and Wass, Mark N and van der Harst, Pim and Holm, Hilma and Sanna, Serena and Kavousi, Maryam and Baumeister, Sebastian E and Coin, Lachlan J and Deng, Guohong and Gieger, Christian and Heard-Costa, Nancy L and Hottenga, Jouke-Jan and Kühnel, Brigitte and Kumar, Vinod and Lagou, Vasiliki and Liang, Liming and Luan, Jian'an and Vidal, Peo Marques and Mateo Leach, Irene and O'Reilly, Paul F and Peden, John F and Rahmioglu, Nilufer and Soininen, Pasi and Speliotes, Elizabeth K and Yuan, Xin and Thorleifsson, Gudmar and Alizadeh, Behrooz Z and Atwood, Larry D and Borecki, Ingrid B and Brown, Morris J and Charoen, Pimphen and Cucca, Francesco and Das, Debashish and de Geus, Eco J. C and Dixon, Anna L and Döring, Angela and Ehret, Georg and Eyjolfsson, Gudmundur I and Farrall, Martin and Forouhi, Nita G and Frieich, Nele and Goessling, Wolfram and Gudbjartsson, Daniel F and Harris, Tamara B and Hartikainen, Anna-Liisa and Heath, Simon and Hirschfield, Gideon M and Hofman, Albert and Homuth, Georg and Hyppönen, Elina and Janssen, Harry L. A and Johnson, Toby and Kangas, Antti J and Kema, Ido P and Kühn, Jens P and Lai, Sana and Lathrop, Mark and Lerch, Markus M and Li, Yun and Liang, T. Jake and Lin, Jing-Ping and Loos, Ruth J. F and Martin, Nicholas G and Moffatt, Miriam F and Montgomery, Grant W and Munroe, Patricia B and Musunuru, Kiran and Nakamura, Yusuke and O'Donnell, Christopher J and Olafsson, Isleifur and Penninx, Brenda W and Pouta, Anneli and Prins, Bram P and Prokopenko, Inga and Puls, Ralf and Ruokonen, Aimo and Savolainen, Markku J and Schlessinger, David and Schouten, Jeoffrey N. L and Seedorf, Udo and Sen-Chowdhry, Srijita and Siminovitch, Katherine A and Smit, Johannes H and Spector, Timothy D and Tan, Wenting and Teslovich, Tanya M and Tukiainen, Taru and Uitterlinden, Ane G and van der Klauw, Melanie M and Vasan, Ramachanan S and Wallace, Chris and Wallaschofski, Henri and Wichmann, H.-Erich and Willemsen, Gonneke and Würtz, Peter and Xu, Chun and Yerges-Armstrong, Laura M and ... and Meta-Anal Glucose Insulin-Related and Diabet Genetics Replication and Genetic Invest Anthropometric and Genetics Liver Dis GOLD Consortium and Global Lipids Genetics Consortium and Alcohol Genome-wide Assoc AlcGen and Int Consortium Blood Pressure ICBP and Meta-analyses of Glucose and Insulin-Related Traits Consortium (MAGIC) and Alcohol Genome-wide Association (AlcGen) Consortium and Genetic Investigation of Anthropometric Traits (GIANT) Consortium and Diabetes Genetics Replication and Meta-analyses (DIAGRAM+) Study and International Consortium for Blood Pressure (ICBP-GWAS) and Genetics of Liver Disease (GOLD) Consortium
Nature genetics, ISSN 1061-4036, 2011, Volume 43, Issue 11, pp. 1131 - U129
Concentrations of liver enzymes in plasma are widely used as indicators of liver disease. We carried out a genome-wide association study in 61,089 individuals,... 
C-REACTIVE PROTEIN | COMMON VARIANTS | METABOLIC SYNDROME | HEPATOCELLULAR-CARCINOMA | RISK-FACTORS | SALT EXPORT PUMP | GENETICS & HEREDITY | SUSCEPTIBILITY LOCI | GENETIC-VARIANTS | HEREDITARY CHOLESTASIS | CORONARY-HEART-DISEASE | Genome-Wide Association Study | Polymorphism, Single Nucleotide | Liver - enzymology | Enzymes - blood | Enzymes - genetics | Humans | Enzymes | Weight control | Data collection | Genetics | Gene loci | Genomes | Gene expression | Autoimmune diseases | Metabolic disorders | Index Medicus
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