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Nucleosides, Nucleotides & Nucleic Acids, ISSN 1525-7770, 01/2018, Volume 37, Issue 12, p. 709
CD73 inhibitors are considered to be used in the therapies of melanomas, gliomas or breast cancer. However, little is known about their pharmacology and... 
Nucleotidase | Urine | Adenosine | Animal models | Intravenous administration | 5'-Nucleotidase | Body weight | Adenosine diphosphate | Breast cancer | Injection | High-performance liquid chromatography | Blood levels | CD73 antigen
Journal Article
Nucleosides, Nucleotides & Nucleic Acids, ISSN 1525-7770, 01/2018, Volume 37, Issue 11, p. 639
4-pyridone-3-carboxamide-1[beta]-D-ribonucleoside (4PYR) is a derivative of nicotinamide found physiologically in human body fluids that can be metabolized to... 
NADPH | NAD | Energy balance | Body fluids | Nitric oxide | Adenine | Nicotinamide | Microvasculature | Metabolism | High-performance liquid chromatography | Endothelial cells | Endothelium
Journal Article
Talanta, ISSN 0039-9140, 05/2018, Volume 182, pp. 492 - 499
Several proteins such as membrane-associated ectonucleotidases: ecto-5’-nucleotidase (E5NT/CD73) and ectonucleoside triphosphate diphosphohydrolase 1... 
Human aortic valves | Calcific aortic valve stenosis | Targeted proteomics | Ectonucleoside triphosphate diphosphohydrolase 1 | Ecto-5’-nucleotidase | Heme oxygenase-1 | CHEMISTRY, ANALYTICAL | OXIDATIVE STRESS | STENOSIS | HUMAN PLASMA | Ecto-5 '-nucleotidase | DEGENERATIVE PROCESS | OVEREXPRESSION | Ectonucleoside triphosphate diphosphohydrolase | METHOD VALIDATION | ENDOTHELIAL-CELLS | DISEASE | MINERALIZATION | BIOMARKER CANDIDATES | Calcinosis - genetics | 5'-Nucleotidase - genetics | Calcinosis - diagnosis | Heme Oxygenase-1 - metabolism | Aortic Valve Stenosis - genetics | Humans | Middle Aged | Male | Case-Control Studies | Aortic Valve - pathology | Heme Oxygenase-1 - genetics | Tandem Mass Spectrometry | Proteolysis | Chromatography, Liquid | Adult | Female | Filtration - methods | Proteomics - methods | Calcinosis - metabolism | Apyrase - analysis | Biomarkers - metabolism | Gene Expression | GPI-Linked Proteins - analysis | Apyrase - metabolism | Specimen Handling - methods | 5'-Nucleotidase - analysis | Aortic Valve Stenosis - diagnosis | Aortic Valve - metabolism | GPI-Linked Proteins - metabolism | Aortic Valve Stenosis - pathology | Heme Oxygenase-1 - analysis | Apyrase - genetics | Aortic Valve Stenosis - metabolism | Aged | Aortic Valve - chemistry | 5'-Nucleotidase - metabolism | Calcinosis - pathology | GPI-Linked Proteins - genetics | Usage | Analysis | Aortic valve stenosis | Heme | Proteomics | Liquid chromatography | Methods | Nucleotidases | Index Medicus
Journal Article
Nucleosides, nucleotides & nucleic acids, 01/2019, p. 1
CD73 inhibitors are considered to be used in the therapies of melanomas, gliomas or breast cancer. However, little is known about their pharmacology and... 
Journal Article
Frontiers in Physiology, ISSN 1664-042X, 03/2017, Volume 8, pp. 127 - 127
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2013, Volume 110, Issue 13, pp. 5109 - 5114
Toll-like receptors (TLRs) are the central players in innate immunity. In particular, TLR9 initiates inflammatory response by recognizing DNA, imported by... 
Heart | Neurons | DNA | Toll like receptors | Myocardium | Antigen presenting cells | Cellular immunity | Macrophages | Cellular differentiation | Endosomes | SYSTEM | ACTIVATED PROTEIN-KINASE | MULTIDISCIPLINARY SCIENCES | CARDIAC-HYPERTROPHY | TOLL-LIKE RECEPTORS | INJURY | ISCHEMIA | CASCADE | STRESS | BACTERIAL-DNA | BRAIN | AMP-Activated Protein Kinases - metabolism | Adenosine Monophosphate - genetics | Rats, Wistar | Toll-Like Receptor 9 - genetics | Adenosine Triphosphate - genetics | Neurons - cytology | Protein Transport - physiology | Inflammation - metabolism | Membrane Transport Proteins - genetics | Adenosine Triphosphate - metabolism | Muscle Proteins - metabolism | Membrane Transport Proteins - metabolism | Neurons - metabolism | Energy Metabolism - physiology | Caenorhabditis elegans - metabolism | Myocytes, Cardiac - cytology | Adenosine Monophosphate - metabolism | Caenorhabditis elegans - genetics | Cells, Cultured | Rats | Nerve Tissue Proteins - genetics | Mice, Knockout | Muscle Proteins - genetics | Nerve Tissue Proteins - metabolism | Animals | Inflammation - genetics | Myocytes, Cardiac - metabolism | Signal Transduction - physiology | Mice | Toll-Like Receptor 9 - metabolism | AMP-Activated Protein Kinases - genetics | Physiological aspects | Toll-like receptors | Research | Heart cells | Tissue | Cardiomyocytes | T cell receptors | Kinases | Metabolism | Deoxyribonucleic acid--DNA | Index Medicus | Biological Sciences
Journal Article
Nucleosides, Nucleotides and Nucleic Acids, ISSN 1525-7770, 11/2018, Volume 37, Issue 11, pp. 639 - 644
4-pyridone-3-carboxamide-1β-D-ribonucleoside (4PYR) is a derivative of nicotinamide found physiologically in human body fluids that can be metabolized to... 
endothelial cells | isolation method | 4-pyridone-3-carboxamide-1β-d-ribonucleoside (4PYR) | mBMECs | primary culture | 4-pyridone-3-carboxamide-1 beta-d-ribonucleoside (4PYR) | ERYTHROCYTES | BIOCHEMISTRY & MOLECULAR BIOLOGY | MODIFIED NUCLEOSIDES | TRIPHOSPHATE
Journal Article
NATURE COMMUNICATIONS, ISSN 2041-1723, 05/2019, Volume 10, Issue 1, pp. 2168 - 15
Adult cardiac tissue undergoes a rapid process of dedifferentiation when cultured outside the body. The in vivo environment, particularly constant... 
HYPERTROPHY | THERAPY | RAT | MULTIDISCIPLINARY SCIENCES | CARDIAC MYOCYTES | TISSUE-SLICES | CARDIOMYOCYTES | SKELETAL | MATURATION | CELL | ISOPROTERENOL | Heart failure | Heart | Transcription | Preservation | Contractility | Tissue culture | Stimulation | Tissues | Muscle contraction | Optimization | Biomimetics | Heart diseases | Culture | Structure-function relationships | Index Medicus
Journal Article
Nucleosides, Nucleotides and Nucleic Acids, ISSN 1525-7770, 2018, Volume 37, Issue 11, pp. 630 - 638
Journal Article
Journal of Molecular and Cellular Cardiology, ISSN 0022-2828, 03/2019, Volume 128, pp. 62 - 76
Vascular inflammation is an important factor in the pathophysiology of cardiovascular diseases, such as atherosclerosis. Changes in the extracellular... 
Adenosine | Inflammation | Adenosine deaminase | Endothelium | CYTOKINES | CARDIAC & CARDIOVASCULAR SYSTEMS | ATHEROSCLEROSIS | RECEPTOR | MECHANISMS | RELEASE | CELL BIOLOGY | NUCLEOTIDE | ADHESION | METABOLISM | EXPRESSION | EXTRACELLULAR ADENOSINE | Cyclodextrins | Analysis | Atherosclerosis
Journal Article