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Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 15998 - 10
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1) belongs to the CD clan of cysteine proteases. MALT1 is a unique enzyme among this... 
PARACASPASE MALT1 | KAPPA-B ACTIVATION | ABC-DLBCL | MULTIDISCIPLINARY SCIENCES | INHIBITORS | CLEAVAGE | PROTEASES | Enzymes | Arginine | Peptides | Substrate specificity | Mucosa | Amino acids | Protein transport | Lymphoma | Probes
Journal Article
Cell Reports, ISSN 2211-1247, 06/2019, Volume 27, Issue 12, pp. 3646 - 3656.e5
Neutrophil granule serine proteases contribute to immune responses through cleavage of microbial toxins and structural proteins. They induce tissue damage and... 
elastase | pyroptosis | cell death | proteinase | inflammation | serpin | apoptosis | gasdermin | cathepsin | neutrophil | APOPTOSIS | EFFECTOR FUNCTIONS | GASDERMIN D | PROTEIN | SERINE PROTEASES | INTERLEUKIN-1-BETA | DIPEPTIDYL PEPTIDASE-I | ELASTASE INHIBITOR | PYROPTOSIS | CELL-DEATH | CELL BIOLOGY
Journal Article
Cell Death and Differentiation, ISSN 1350-9047, 2019
Caspases participate in regulated cell death mechanisms and are divided into apoptotic and proinflammatory caspases. The main problem in identifying the unique... 
Journal Article
Nature, ISSN 0028-0836, 10/2015, Volume 526, Issue 7575, pp. 666 - 671
Journal Article
Cell death and differentiation, ISSN 1350-9047, 04/2019
Most caspases can be positioned unambiguously within the regulated cell death networks of apoptosis and pyroptosis, but the role of caspase-2, a highly... 
Journal Article
Biochemical Journal, ISSN 0264-6021, 04/2012, Volume 443, Issue 1, pp. 287 - 295
The paracaspase domain of MALT1 (mucosa-associated lymphoid tissue lymphoma translocation protein 1) is a component of a gene translocation fused to the... 
CYLD | Positional-scanning substrate library | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1) | Protease | Substrate specificity | Paracaspase | TRANSLOCATION | ACTIVATION | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | CLEAVAGE | positional-scanning substrate library | protease | substrate specificity | CASPASES | LYMPHOMA | mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1) | paracaspase | NF-KAPPA-B | ZYMOGEN | KEY | Protein Structure, Tertiary | Recombinant Fusion Proteins - biosynthesis | Amino Acid Sequence | Recombinant Fusion Proteins - isolation & purification | Neoplasm Proteins - biosynthesis | Escherichia coli | Humans | Substrate Specificity | Neoplasm Proteins - chemistry | Recombinant Fusion Proteins - chemistry | Caspases - isolation & purification | Citrates - chemistry | Chromatography, Affinity | Neoplasm Proteins - isolation & purification | Proteolysis | Enzyme Activators - chemistry | Caspases - biosynthesis | HEK293 Cells | Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein | Enzyme Activation | Kinetics | Protein Stability | Caspases - chemistry | Oligopeptides - chemistry | Index Medicus | PS-SCL, positional-scanning substrate combinatorial library | WT, wild-type | CARD, caspase recruitment domain | MALT1, mucosa-associated lymphoid tissue lymphoma translocation protein 1 | HEK, human embryonic kidney | AFC, 7-amino-4-trifluoromethylcoumarin | JNK, c-Jun N-terminal kinase | DTT, dithiothreitol | IAP, inhibitor of apoptosis protein | z, benzyloxycarbonyl | ACC, 7-amino-4-carbamoylmethylcoumarin | DD, death domain | CARMA1, CARD-containing MAGUK (membrane-associated guanylate kinase) 1 | TCA, trichloroacetic acid | Ac, acetyl | AMC, 7-amino-4-methylcoumarin | FMK, fluoromethylketone | IPTG, isopropyl β-D-thiogalactopyranoside | NF-κB, nuclear factor κB | FKBP, FK506-binding protein | BIR, baculovirus inhibitor of apoptosis protein repeat | Ni-NTA, Ni2+-nitrilotriacetate | NIK, NF-κB-inducing kinase | cIAP2, cellular inhibitor of apoptosis protein 2
Journal Article
Cell Death and Differentiation, ISSN 1350-9047, 02/2019, Volume 26, Issue 2, pp. 229 - 244
Apical caspases initiate and effector caspases execute apoptosis. Reagents that can distinguish between caspases, particularly apical caspases-8, 9, and 10 are... 
TARGET | ACTIVATION | TRAIL | SPECIFICITY | RECOMBINANT | BIOCHEMISTRY & MOLECULAR BIOLOGY | XIAP | SUBSTRATE LIBRARY | BIMODAL INHIBITION | PROTEASE | FAMILY | CELL BIOLOGY | Caspase-8 | Peptides | Cell death | Caspase-9 | Caspase | Breast cancer | Lymphocytes T | Quantitation | Apoptosis
Journal Article