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Annals of Oncology, ISSN 0923-7534, 11/2015, Volume 26, Issue suppl 7, pp. vii7.3 - vii7
Journal Article
Annals of Oncology, ISSN 0923-7534, 11/2015, Volume 26, Issue suppl 7, pp. vii40.1 - vii40
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 08/2017, Volume 377, Issue 9, pp. 829 - 838
Alectinib, a potent ALK tyrosine kinase inhibitor, was more effective and somewhat less toxic than crizotinib when used as primary therapy in patients with ALK... 
RESISTANT | MEDICINE, GENERAL & INTERNAL | MODELS | ANTITUMOR-ACTIVITY | INHIBITOR ALECTINIB | CHEMOTHERAPY | Lung Neoplasms - drug therapy | Pyrazoles - therapeutic use | Follow-Up Studies | Lung Neoplasms - mortality | Humans | Middle Aged | Male | Antineoplastic Agents - therapeutic use | Protein Kinase Inhibitors - adverse effects | Central Nervous System Neoplasms - secondary | Young Adult | Pyridines - adverse effects | Anaplastic Lymphoma Kinase | Antineoplastic Agents - adverse effects | Aged, 80 and over | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Adult | Female | Receptor Protein-Tyrosine Kinases - analysis | Pyrazoles - adverse effects | Pyridines - therapeutic use | Crizotinib | Carbazoles - adverse effects | Kaplan-Meier Estimate | Carcinoma, Non-Small-Cell Lung - mortality | Disease-Free Survival | Animals | Piperidines - therapeutic use | Protein Kinase Inhibitors - therapeutic use | Piperidines - adverse effects | Intention to Treat Analysis | Carbazoles - therapeutic use | Carcinoma, Non-Small-Cell Lung - drug therapy | Central Nervous System Neoplasms - drug therapy | Drugs | Care and treatment | Analysis | Comparative analysis | Lung cancer, Non-small cell | Health aspects | Systemic diseases | Toxicity | Lung cancer | Central nervous system | Non-small cell lung carcinoma | Oncology | Nervous system | Metastasis | Radiation therapy | Patients | Lymphoma | Cancer therapies | Survival | Mutation | Protein-tyrosine kinase | Drug dosages | Tumors | Index Medicus | Abridged Index Medicus
Journal Article
Lancet, The, ISSN 0140-6736, 2015, Volume 386, Issue 9998, pp. 1049 - 1056
Journal Article
Neuron, ISSN 0896-6273, 12/2015, Volume 88, Issue 5, pp. 902 - 909
A non-coding hexanucleotide repeat expansion in the gene is the most common mutation associated with familial amyotrophic lateral sclerosis (ALS) and... 
RAN translation | transgenic mice | Amyotrophic lateral sclerosis (ALS) | frontotemporal dementia (FTD) | neurodegeneration | microRNA | repeat expansions | C9ORF72 | RNA foci | Repeat expansions | MicroRNA | Neurodegeneration | Transgenic mice | Frontotemporal dementia (FTD) | DEMENTIA | ALS | AMYOTROPHIC-LATERAL-SCLEROSIS | SPECTRUM | MODEL | FRONTOTEMPORAL LOBAR DEGENERATION | TRANSLATION | SENSE | NEUROSCIENCES | PATHOLOGICAL FEATURES | Age Factors | Amyotrophic Lateral Sclerosis - physiopathology | DNA Repeat Expansion - genetics | Humans | MicroRNAs - metabolism | Frontotemporal Dementia - mortality | Cerebral Cortex - cytology | Brain - metabolism | Chromosomes, Artificial, Bacterial - genetics | Chromosomes, Artificial, Bacterial - metabolism | Neurons - physiology | C9orf72 Protein | Dipeptides - metabolism | Neurons - drug effects | Disease Models, Animal | Frontotemporal Dementia - pathology | Frontotemporal Dementia - genetics | Frontotemporal Dementia - physiopathology | Gene Expression Regulation - genetics | Amyotrophic Lateral Sclerosis - genetics | Cells, Cultured | Genotype | Mice, Transgenic | Amyotrophic Lateral Sclerosis - mortality | Nerve Tissue Proteins - metabolism | Proteins - genetics | Amyotrophic Lateral Sclerosis - pathology | Animals | Brain - pathology | In Vitro Techniques | Dipeptides - genetics | Proteins | Neurosciences | Proline | Genetic engineering | Glycine | Dementia | Analysis | Genetic translation | Plasmids | Neurons | Rodents | Cloning | Amyotrophic lateral sclerosis | Behavior | Artificial chromosomes | Expansion
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 11/2017, Volume 377, Issue 20, pp. 1986 - 1988
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 06/2017, Volume 376, Issue 25, pp. 2415 - 2426
Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2015, Volume 16, Issue 16, pp. 1651 - 1658
Journal Article
Cancer Cell, ISSN 1535-6108, 05/2018, Volume 33, Issue 5, pp. 791 - 793
In this issue of , Hellmann et al. describe in two clinical trials the importance of tumor mutational burden as an independent predictive marker for outcomes... 
CTLA-4 BLOCKADE | MELANOMA | ONCOLOGY | MUTATIONAL LANDSCAPE | OPEN-LABEL | NIVOLUMAB PLUS IPILIMUMAB | CELL BIOLOGY | Care and treatment | Immunotherapy | Ipilimumab | Genetic aspects | Metastasis | Lung cancer, Non-small cell | Drug therapy | Cancer
Journal Article