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1. Full Text Label-free nanoplasmonic sensing of tumor-associate autoantibodies for early diagnosis of colorectal cancer
by Soler, Maria and Estevez, M.-Carmen and Villar-Vazquez, Roi and Casal, J. Ignacio and Lechuga, Laura M
Analytica Chimica Acta, ISSN 0003-2670, 08/2016, Volume 930, pp. 31 - 38
Colorectal cancer is treatable and curable when detected at early stages. However there is a lack of less invasive and more specific screening and diagnosis... 
Plasma | Serum | Autoantibodies | Clinical diagnosis | Colorectal cancer | Nanoplasmonic biosensor | CHEMISTRY, ANALYTICAL | PROTEIN | GUIDELINES | VALIDATION | ANTIGENS | COLON-CANCER | BIOMARKERS | Biomarkers, Tumor - blood | Limit of Detection | Colorectal Neoplasms - immunology | Colorectal Neoplasms - blood | Early Detection of Cancer | Humans | Nanotechnology - instrumentation | Autoantibodies - biosynthesis | Colorectal Neoplasms - diagnosis | Autoimmunity | Biological products | Detectors | Diagnosis | Nanotechnology | Tumors | Cancer | Nanostructure | Biosensors | Devices | Patients | Blood | ELISA
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2. Full Text Impact of late presentation of HIV infection on short-, mid- and long-term mortality and causes of death in a multicenter national cohort: 2004–2013
by Sobrino-Vegas, Paz and Moreno, Santiago and Rubio, Rafael and Viciana, Pompeyo and Bernardino, José Ignacio and Blanco, José Ramón and Bernal, Enrique and Asensi, Víctor and Pulido, Federico and del Amo, Julia and Hernando, Victoria and Cohorte Red Invest Sida and Cohorte de la Red de Investigación en Sida, Spain
Journal of Infection, ISSN 0163-4453, 2016, Volume 72, Issue 5, pp. 587 - 596
Summary Objectives To analyze the impact of late presentation (LP) on overall mortality and causes of death and describe LP trends and risk factors... 
Infectious Disease | HIV | Causes of death | Mortality | Factors and trends | Cohort study | Late presentation | INFECTIOUS DISEASES | DELAYED DIAGNOSIS | RISK-FACTORS | INITIATION | LATE PRESENTERS | CARE | COUNTRY | ACTIVE ANTIRETROVIRAL THERAPY | WALES | CONSEQUENCES | ENGLAND | Humans | Middle Aged | Risk Factors | Male | Delayed Diagnosis | Cause of Death | Spain - epidemiology | HIV Infections - diagnosis | Survival Analysis | Adult | Female | HIV Infections - mortality | Aged | Cohort Studies | HIV (Viruses) | Health aspects | HIV infection | Analysis
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3. Full Text Prediction of long-term outcomes of HIV-infected patients developing non-AIDS events using a multistate approach
by Masiá, Mar and Padilla, Sergio and Moreno, Santiago and Barber, Xavier and Iribarren, Jose A and Del Romero, Jorge and Gómez-Sirvent, Juan L and Rivero, María and Vidal, Francesc and Campins, Antonio A and Gutiérrez, Félix and Del Amo, Julia and Dalmau, David and Navarro, Maria Luisa and González, Maria Isabel and Soriano, Vicente and Garcia, Federico and Rubio, Rafael and Iribarren, Jose Antonio and Hernández, Beatriz and Berenguer, Juan and Sobrino, Paz and Hernando, Victoria and Alejos, Belén and Álvarez, Débora and Monge, Susana and Jarrín, Inma and Rivero, Yaiza and González, Cristina and Muñoz-Fernández, M Angeles and García-Merino, Isabel and Rico, Coral Gómez and De La Fuente, Jorge Gallego and Torre, Almudena García and Portilla, Joaquín and Merino, Esperanza and Reus, Sergio and Boix, Vicente and Giner, Livia and Gadea, Carmen and Portilla, Irene and Pampliega, Maria and Díez, Marcos and Rodríguez, Juan Carlos and Sánchez-Payá, Jose and Podzamczer, Daniel and Imaz, Elena Fer-rerm Arkaitz and Van Den Eyncle, Evan and Di Yacovo, Silvana and Sumoy, Maria and Gómez, Juan Luis and Rodríguez, Patricia and Alemán, María Remedios and Del Mar Alonso, María and Hernández, María Inmaculada and Díaz-Flores, Felicitas and García, Dácil and Pelazas, Ricardo and Labarga, Pablo and Barreiro, Pablo and Rivas, Pablo and Blanco, Francisco and Carbonero, Luz Martín and Vispo, Eugenia and Solera, Carmen and Asensi, Victor and Valle, Eulalia and Cartón, José Antonio and Pérez, Vicente Estrada and Molina, Maria Jesus Téllez and García, Jorge Vergas and Carrera, Elisa Pérez-Cecila and Pulido, Federico and Bisbal, Otilia and Matarranz, Mariano and Lagarde, Maria and Rubio-Martín, Rafael and Hernando, Asunción and Portillo, Angel and Iribarren, Jose Antonio and Arrizabalaga, Julio and Aramburu, María José and Camino, Xabier and Rodríguez-Arrondo, Francisco and Von Wichmann, Miguel Ángel and Tomé, Lidia Pascual and Goenaga, Miguel Ángel and Bustinduy, Ma Jesús and Galparsoro, Harkaitz Azkune and Ibarguren, Maialen and Aguado, Mirian and Masiá, Mar and Padilla, Sergio and Fernández, Marta and García, Elena and Navarro, Andrés and Montolio, Fernando and Robledano, Catalina and Colomé, Joan Gregori and Adsuar, Araceli and ... and Cohorte Red Invest Sida CoRIS and Cohorte de la Red de Investigación en Sida (CoRIS)
PLoS ONE, ISSN 1932-6203, 09/2017, Volume 12, Issue 9, p. e0184329
Objetives Outcomes of people living with HIV (PLWH) developing non-AIDS events (NAEs) remain poorly defined. We aimed to classify NAEs according to severity,... 
GENERAL-POPULATION | MODELS | MORBIDITY | MULTIDISCIPLINARY SCIENCES | ANTIRETROVIRAL THERAPY | COMPETING RISKS | COHORT | DEATH | HUMAN-IMMUNODEFICIENCY-VIRUS | DISEASE PROGRESSION | AGE | Prognosis | Outcome Assessment (Health Care) | Comorbidity | HIV Infections - epidemiology | HIV Infections - virology | Humans | Mortality | Male | CD4 Lymphocyte Count | Cause of Death | Viral Load | Incidence | HIV Infections - immunology | Spain - epidemiology | Female | HIV Infections - mortality | Transition probabilities | Antiretroviral drugs | Ribonucleic acid--RNA | Medical diagnosis | CD4 antigen | Confidence intervals | Hepatitis | Demographics | Acquired immune deficiency syndrome--AIDS | Human immunodeficiency virus--HIV | Predictions | Death | Hepatitis C virus | Hepatitis C | RNA | Ribonucleic acid | AIDS | HIV | Acquired immune deficiency syndrome | Human immunodeficiency virus
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4. Full Text MicroRNA profile in CD8+ T-lymphocytes from HIV-infected individuals: Relationship with antiviral immune response and disease progression
by Egaña-Gorroño, Lander and Guardo, Alberto C and Bargalló, Manel E and Planet, Evarist and Vilaplana, Elisenda and Escribà, Tuixent and Pérez, Iñaki and Gatell, Josep Maria and García, Felipe and Arnedo, Mireia and Plana M, Montserrat and Pineda, Juan Antonio and Sánchez, Eva Recio and De León, Fernando Lozano and Macías, Juan and Palomares, José Carlos and Parra, Manuel and Gómez-Mateos, Jesús and Martínez-Madrid, Onofre Juan and Vera, Francisco and Martínez, Lorena and Miró, José M and Manzardo, Christian and Zamora, Laura and García, Ma. Teresa and Ligero, Carmen and Blanco, José Luis and García-Alcaide, Felipe and Martínez, Esteban and Mallolas, Josep and Gatell, José M and Portilla, Joaquín and Merino, Esperanza and Reus, Sergio and Boix, Vicente and Giner, Livia and Gadea, Carmen and Portilla, Irene and Pampliega, Maria and Díez, Marcos and Rodríguez, Juan Carlos and Sánchez-Payá, Jose and Podzamczer, Daniel and Imaz, Elena Ferrerm Arkaitz and Van Den Eyncle, Evan and Di Yacovo, Silvana and Sumoy, Maria and Gómez, Juan Luis and Rodríguez, Patricia and Alemán, María Remedios and Alonso, María Del Mar and Hernández, María Inmaculada and Díaz-Flores, Felicitas and García, Dácil and Pelazas, Ricardo and Soriano, Vicente and Labarga, Pablo and Barreiro, Pablo and Rivas, Pablo and Blanco, Francisco and Carbonero, Luz Martín and Vispo, Eugenia and Solera, Carmen and Asensi, Victor and Valle, Eulalia and Cartón, José Antonio and Rubio, Rafael and Pulido, Federico and Matarranz, Mariano and Lagarde, Maria and Maestro, Guillermo and Rubio-Martín, Rafael and Iribarren, José Antonio and Arrizabalaga, Julio and Aramburu, María José and Camino, Xabier and Rodríguez-Arrondo, Francisco and Von Wichmann, Miguel Ángel and Tomé, Lidia Pascual and Goenaga, Miguel Ángel and Bustinduy, Ma. Jesús and Galparsoro, Harkaitz Azkune and Ibarguren, Maialen and Aguado, Mirian and Gutiérrez, Félix and Masiá, Mar and López, Cristina and Padilla, Sergio and Navarro, Andrés and Montolio, Fernando and Robledano, Catalina and Colomé, Joan Gregori and Adsuar, Araceli and Pascual, Rafael and Carlos, Federico and Martinez, Maravillas and Muga, Roberto and Tor, Jordi and Sanvisens, Arantza and Berenguer, Juan and ... and HIV Controllers Consortium AIDS and HIV Controllers Consortium of the AIDS Spanish Network
PLoS ONE, ISSN 1932-6203, 05/2016, Volume 11, Issue 5, p. e0155245
Background The relationship between host microRNAs (miRNA), viral control and immune response has not yet been elucidated in the field of HIV. The aim of this... 
EFFECTOR | T-CELL DIFFERENTIATION | ACTIVATION | BIOINFORMATICS | MEMORY | MULTIDISCIPLINARY SCIENCES | SENSITIVITY | CD4(+) | ABSENCE | EXPRESSION | MIR-181A | Anti-HIV Agents - pharmacology | Reproducibility of Results | HIV Infections - genetics | Humans | Middle Aged | Male | MicroRNAs - metabolism | Gene Expression Profiling | Disease Progression | Immunity - drug effects | HIV Infections - immunology | HIV Infections - pathology | Adult | Anti-HIV Agents - therapeutic use | Female | HIV Infections - drug therapy | MicroRNAs - genetics | CD8-Positive T-Lymphocytes - immunology | Real-Time Polymerase Chain Reaction | Complications and side effects | Care and treatment | MicroRNA | Analysis | Influence | Cellular signal transduction | Research | HIV infection | Enrichment | Controllers | Antiretroviral drugs | Immune response | Control methods | CD8 antigen | Genes | MiRNA | Lymphocytes T | CD3 antigen | T cell receptors | Gene expression | CD28 antigen | Ribonucleic acid--RNA | Disease control | Acquired immune deficiency syndrome--AIDS | Lymphocytes | Human immunodeficiency virus--HIV | Transduction | Apoptosis | Immune system | RNA | Ribonucleic acid | AIDS | HIV | Acquired immune deficiency syndrome | Human immunodeficiency virus
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5. Full Text Use of cohort data to estimate national prevalence of transmitted drug resistance to antiretroviral drugs in Spain (2007–2012)
by Monge, S and Díez, M and Alvarez, M and Guillot, V and Iribarren, J.A and Palacios, R and Delgado, R and Jaén, A and Blanco, J.R and Domingo, P and Portilla, J and Pérez Elías, M.J and Garcia, F and Cohorte de la Red de Investigación en Sida (CoRIS)
Clinical Microbiology and Infection, ISSN 1198-743X, 01/2015, Volume 21, Issue 1, pp. 105.e1 - 105.e5
Prevalence of transmitted drug resistance (pTDR) to antiretroviral drugs in Spain (2007–2012) was estimated using the CoRIS cohort, adjusting its territorial... 
cohort studies | human immunodeficiency virus | epidemiological monitoring | drug resistance | Antiretroviral agents | Human immunodeficiency virus | Drug resistance | Epidemiological monitoring | Cohort studies | Anti-HIV Agents - pharmacology | Prevalence | Prospective Studies | HIV-1 - drug effects | HIV Infections - epidemiology | HIV Infections - virology | Humans | Middle Aged | Drug Resistance, Viral | Male | Young Adult | Spain - epidemiology | Adolescent | Adult | Anti-HIV Agents - therapeutic use | Female | HIV Infections - drug therapy
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6. Full Text Incidence of Hepatitis C Virus (HCV) in a multicenter cohort of HIV-positive patients in Spain 2004-2011: Increasing rates of HCV diagnosis but not of HCV seroconversions
by Sobrino-Vegas, Paz and Monge Corella, Susana and Serrano-Villar, Sergio and Gutiérrez, Félix and Masiá, Mar and López Rodríguez, Cristina and Padilla, Sergio and Navarro, Andrés and Montolio, Fernando and Robledano García, Catalina and Colomé, Joan Gregori and Blanco, José Ramón and Santos, Ignacio and Del Romero, Jorge and Segura, Ferrán and Portilla, Joaquín and Guillén, Santiago Moreno and Del Amo, Julia and García, Federico and Ángeles Muñoz, María and Hernando Sebastián, Victoria and Alejos Ferreras, Belén and Álvarez, Débora and Monge, Susana and Jarrín, Inmaculada and Rivero, Yaiza and González Blázquez, Cristina and Muñoz-Fernández, M. Ángeles and García-Merino, Isabel and Gómez Rico, Coral and Gallego De La Fuente, Jorge and García Torre, Almudena and Portilla Sogorb, Joaquín and Merino De Lucas, Esperanza and Bañuls, Sergio Reus and Martínez, Vicente Boix and Oncina, Livia Giner and Pastor, Carmen Gadea and Portilla Tamarit, Irene and Toledo, Patricia Arcaina and Gómez Sirvent, Juan Luis and Rodríguez Fortúnez, Patricia and Alemán Valls, María Remedios and Del Mar Alonso Socas, María and López Lirola, Ana María and Hernández Hernández, María Inmaculada and Díaz-Flores, Felicitas and Soriano, Vicente and Labarga, Pablo and Barreiro, Pablo and Rivas, Pablo and Blanco, Francisco and Carbonero, Luz Martín and Vispo, Eugenia and Solera, Carmen and Asensi, Victor and Valle, Eulalia and Cartón, José Antonio and Miró, José M and López-Dieguez, María and Manzardo, Christian and Zamora, Laura and Pérez, Iñaki and García, Ma. Teresa and Ligero, Carmen and Blanco, José Luis and García-Alcaide, Felipe and Martínez, Esteban and Mallolas, Josep and Gatell, José M and Rubio, Rafael and Pulido, Federico and Fiorante, Silvana and Llenas, Jara and Rodríguez, Violeta and Matarranz, Mariano and Iribarren, José Antonio and Arrizabalaga, Julio and Aramburu, María José and Camino, Xabier and Rodríguez-Arrondo, Francisco and Von Wichmann, Miguel Angel and Tomé, Lidia Pascual and Goenaga, Miguel Ángel and Bustinduy, Ma. Jesús and Galparsoro, Harkaitz Azkune and Clotet, Bonaventura and Tural, Cristina and Ruiz, Lidia and Miranda, Cristina and Muga, Roberto and Tor, Jordi and Sanvisens, Arantza and Berenguer, Juan and López Bernaldo De Quirós, Juan Carlos and Miralles, Pilar and Ochaíta, Jaime Cosín and Gutiérrez Cuellar, Isabel Á and Ramírez Schacke, Margarita and Padilla Ortega, Belén and ... and CoRIS
PLoS ONE, ISSN 1932-6203, 12/2014, Volume 9, Issue 12, p. e116226
Objectives: We aim to describe rates and risk factors of Hepatitis C Virus (HCV) diagnoses, follow-up HCV testing and HCV seroconversion from 2004-2011 in a... 
INFECTED MEN | EPIDEMIC | OUTBREAK | CLUSTER | SEXUAL TRANSMISSION | MULTIDISCIPLINARY SCIENCES | Prospective Studies | Hepacivirus - immunology | HIV Infections - epidemiology | HIV Infections - virology | Humans | Middle Aged | Risk Factors | Substance Abuse, Intravenous - epidemiology | Male | Incidence | Young Adult | Hepatitis C - diagnosis | Spain - epidemiology | Hepatitis C - epidemiology | Hepatitis C - virology | Sexuality | Substance Abuse, Intravenous - virology | Adult | Female | Poisson Distribution | Aged | Highly active antiretroviral therapy | Antiviral agents | Care and treatment | HIV patients | Hepatitis C virus | HIV (Viruses) | Health aspects | Drug abuse | Sex | Viruses | Infections | Serology | Medical diagnosis | Epidemiology | Risk factors | Hepatitis | Sexually transmitted diseases | Immunology | Acquired immune deficiency syndrome--AIDS | Antiretroviral agents | Human immunodeficiency virus--HIV | Poisson density functions | Statistical analysis | Health risks | Regression analysis | Risk analysis | Patients | Seroconversion | Antiretroviral therapy | CD4 antigen | Hepatitis C | Health risk assessment | Espanya | VIH (Virus) | HIV-positive persons | Persones seropositives | Spain | Acquired immune deficiency syndrome | AIDS | HIV | Human immunodeficiency virus
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7. Full Text Pneumonia treated in the internal medicine department: focus on healthcare-associated pneumonia
by Giannella, M and Pinilla, B and Capdevila, J.A and Alarcón, J. Martínez and Muñoz, P and Álvarez, J. López and Bouza, E and SEMI
Clinical Microbiology and Infection, ISSN 1198-743X, 08/2012, Volume 18, Issue 8, pp. 786 - 794
Patients with pneumonia treated in the internal medicine department (IMD) are often at risk of healthcare-associated pneumonia (HCAP). The importance of HCAP... 
healthcare-associated pneumonia | internal medicine | hospitalized pneumonia patient | Community-acquired pneumonia | hospital-acquired pneumonia | Community‐acquired pneumonia | hospital‐acquired pneumonia | healthcare‐associated pneumonia | Hospital-acquired pneumonia | Hospitalized pneumonia patient | Internal medicine | Healthcare-associated pneumonia | UNITED-STATES | INFECTIOUS DISEASES | MANAGEMENT | GUIDELINES | ADULTS | MICROBIOLOGY | IDENTIFICATION | REQUIRING HOSPITAL ADMISSION | ANTIBIOTIC-THERAPY | OUTCOMES | EPIDEMIOLOGY | Pneumonia | Lung diseases, Obstructive | Analysis | Bacterial pneumonia | Staphylococcus aureus infections | Cross infection | Nosocomial infections | Drug therapy | Risk factors
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8. Full Text Transmitted drug resistance to rilpivirine in newly diagnosed antiretroviral naive adults
by Alvarez, M and Monge, S and Chueca, N and Guillot, V and Viciana, P and Anta, L and Rodriguez, C and Gomez-Sirvent, J.L and Navarro, G and Santos, I. de los and Moreno, S and García, F and Cohorte de la Red de Investigación en Sida
Clinical Microbiology and Infection, ISSN 1198-743X, 01/2015, Volume 21, Issue 1, pp. 104.e1 - 104.e5
We characterized transmitted drug resistance to rilpivirine and the predicted efficacy of first-line rilpivirine-containing regimens in antiretroviral-naive... 
Naive adults | therapeutic barrier | resistance mutations | rilpivirine | Resistance mutations | Therapeutic barrier | Rilpivirine | Anti-HIV Agents - pharmacology | Prevalence | Nitriles - pharmacology | HIV-1 - drug effects | HIV Infections - epidemiology | HIV Infections - virology | Humans | Pyrimidines - pharmacology | HIV-1 - genetics | Mutation - genetics | Drug Resistance, Viral - genetics | Adult
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9. Full Text Evaluation of Breast Cancer Patients with Genetic Risk in a University Hospital: Before and After the Implementation of a Heredofamilial Cancer Unit
by Lobo, Miriam and López-Tarruella, Sara and Luque, Soledad and Lizarraga, Santiago and Flores-Sánchez, Carmen and Bueno, Oscar and Solera, Jesús and Jerez, Yolanda and del Val, Ricardo González and Palomero, María Isabel and Cebollero, María and Echavarría, Isabel and Torres, Gabriela and Martín, Miguel and Márquez-Rodas, Iván
Journal of Genetic Counseling, ISSN 1059-7700, 8/2018, Volume 27, Issue 4, pp. 854 - 862
The identification of patients at risk for breast cancer by genetic testing has proven to reduce breast cancer mortality. In 2010, due to a lack of... 
Human Genetics | Ethics | Public Health | Biomedicine | Genetic counseling | Gynecology | Multidisciplinary approach | Clinical Psychology | Hereditary breast cancer | BRCA1 | BRCA2 | BRCA2 MUTATION CARRIERS | SURVIVAL | MASTECTOMY | HEREDITARY CANCER | METAANALYSIS | SOCIAL SCIENCES, BIOMEDICAL | OVARIAN-CANCER | FAMILY-HISTORY | OLAPARIB | COLORECTAL-CANCER | GENETICS & HEREDITY | HEALTH POLICY & SERVICES | AMERICAN SOCIETY | Genetic Predisposition to Disease | Genetic Testing - statistics & numerical data | Humans | Middle Aged | Risk Factors | Genetic Testing - methods | Medical Oncology - organization & administration | Breast Neoplasms - prevention & control | Spain | Hospitals, University - organization & administration | Ovarian Neoplasms - genetics | Adult | Female | Breast Neoplasms - diagnosis | Retrospective Studies | Prevention | Care and treatment | Medical genetics | Medical records | Breast cancer | Genetic aspects | Diagnosis | Health aspects | Risk factors | Genetic screening | Cancer | High risk | At risk | Risk groups | Genetic susceptibility | BRCA1 protein | Referrals | Mortality | Risk reduction | Mammography | Family medical history | Counselling | Ovarian cancer | Medical referrals | Genetic family histories | Mutation | Detection | Interdisciplinary approach | Health risk assessment | Genetic counselling
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10. Full Text Data Balancing for Efficient Training of Hybrid ANN/HMM Automatic Speech Recognition Systems
by Garcia-Moral, A I and Solera-Urena, R and Pelaez-Moreno, C and Diaz-de-Maria, F
IEEE Transactions on Audio, Speech, and Language Processing, ISSN 1558-7916, 03/2011, Volume 19, Issue 3, pp. 468 - 481
Hybrid speech recognizers, where the estimation of the emission pdf of the states of hidden Markov models (HMMs), usually carried out using Gaussian mixture... 
artificial neural networks (ANNs) | Noise reduction | Active learning | Artificial neural networks | MLP/HMM | ANN/HMM | multilayer perceptrons (MLPs) | machine learning | robust ASR | Automatic speech recognition | Databases | Working environment noise | hybrid automatic speech recognition (ASR) | Hidden Markov models | Training data | Speech recognition | additive noise | hidden Markov models (HMMs) | State estimation | Testing | IMBALANCE | ENGINEERING, ELECTRICAL & ELECTRONIC | ACOUSTICS | COST | MODELS | SELECTION | DATA SETS | Studies | Neural networks | Algorithms | Training | Trains | Speech | Mathematical models | Learning theory | Sifting
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