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Journal of Medicinal Chemistry, ISSN 0022-2623, 05/2014, Volume 57, Issue 9, pp. 3755 - 3772
It is urgent to introduce new drugs for tuberculosis to shorten the prolonged course of treatment and control drug-resistant Mycobacterium tuberculosis (Mtb).... 
Microbial Sensitivity Tests | Structure-Activity Relationship | Pyranocoumarins - pharmacology | Mycobacterium tuberculosis - drug effects | Antitubercular Agents - pharmacology | Mycobacterium tuberculosis - growth & development
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2016, Volume 113, Issue 31, pp. E4523 - E4530
Journal Article
Asian Journal of Organic Chemistry, ISSN 2193-5807, 07/2019, Volume 8, Issue 7, pp. 1053 - 1057
As part of a program to explore the chemistry of β‐lactams and their derivatives, we prepared a focused set of benzazetidine, indoline, and indole... 
Heterocycles | Amides | C−H activation | β-Lactams | Benzazetidines | CYCLOADDITION | C-H activation | CHEMISTRY, ORGANIC | beta-Lactams
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 06/2017, Volume 114, Issue 24, pp. E4832 - E4840
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 06/2017, Volume 114, Issue 24, p. E4832
Mycobacterium tuberculosis (Mtb) encounters stresses during the pathogenesis and treatment of tuberculosis (TB) that can suppress replication of the bacteria... 
Drugs | Identification methods | Pathogenesis | Agar | Cultures | RNA polymerase | Rifamycin | Rifamycins | DNA-directed RNA polymerase | Cells | Strain | Polymerase | Artifacts | Dilution | Tuberculosis | Thioridazine | Antibiotics | Ribonucleic acids | Sputum | RpoB protein | Bacteria | Mutation | Rifampin
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 06/2017, Volume 114, Issue 24, pp. E4832 - E4840
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 05/2014, Volume 57, Issue 9, pp. 3755 - 3772
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 08/2016, Volume 113, Issue 31, p. E4523
  The rising incidence of antimicrobial resistance (AMR) makes it imperative to understand the underlying mechanisms. Mycobacterium tuberculosis (Mtb) is the... 
Transcription factors | DNA methylation | Bacteria | Catalysis | Binding sites
Journal Article
Proceedings of the National Academy of Sciences, USA, ISSN 0027-8424, 08/2016, Volume 113, Issue 31, pp. E4523 - E4523
The rising incidence of antimicrobial resistance (AMR) makes it imperative to understand the underlying mechanisms. Mycobacterium tuberculosis (Mtb) is the... 
Journal Article
by Mu, R and Kong, CC and Yu, WJ and Wang, HY and Ma, Y and Li, XY and Wu, J and Somersan-Karakaya, S and Li, HT and Sun, ZG and Liu, G
ACS INFECTIOUS DISEASES, ISSN 2373-8227, 06/2019, Volume 5, Issue 6, pp. 949 - 961
Firstly, this study demonstrated that natural product-inspired coumarin-based nitrofuranyl calanolides (NFCs) can form the Rv2466c-mycothiol (MSH)-NFC (RvMN)... 
MORTALITY | INFECTIOUS DISEASES | ACTIVATION | CHEMISTRY, MEDICINAL | fluorescent probe | COMPONENTS | diagnosis | XPERT MTB/RIF | drug-susceptibility testing | Rv2466c
Journal Article
ACS Infectious Diseases, ISSN 2373-8227, 12/2015, Volume 1, Issue 12, pp. 580 - 585
Identification of compounds that target metabolically diverse subpopulations of Mycobacterium tuberculosis (Mtb) may contribute to shortening the course of... 
nonreplicating M. tuberculosis | high-throughput screen | reactive nitrogen species
Journal Article
ACS INFECTIOUS DISEASES, ISSN 2373-8227, 08/2019, Volume 5, Issue 8, pp. 1433 - 1445
The historical view of beta-lactams as ineffective antimycobacterials has given way to growing interest in the activity of this class against Mycobacterium... 
Mycobacterium | antimycobacterial | INFECTIOUS DISEASES | CHEMISTRY, MEDICINAL | CRYSTAL-STRUCTURE | tuberculosis | ENZYMATIC-HYDROLYSIS | FLUOROGENIC PROBES | cephalosporin | CLAVULANIC ACID | PRODRUG ACTIVATION | IN-VITRO | ANTIBACTERIAL ACTIVITY | 3-QUINOLONE ESTERS | pyrithione | beta-lactamase | ANTIMICROBIAL ACTIVITY
Journal Article
ACS Infectious Diseases, ISSN 2373-8227, 05/2018, Volume 4, Issue 5, pp. 771 - 787
Journal Article
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