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1. Full Text Unicompartmental versus total knee arthroplasty database analysis
by Lyons, Matthew C and MacDonald, Steven J and Somerville, Lyndsay E and Naudie, Douglas D and McCalden, Richard W
Clinical Orthopaedics and Related Research, ISSN 0009-921X, 2012, Volume 470, Issue 1, pp. 84 - 90
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2. Full Text Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes): a double-blind, randomised placebo-controlled trial
by Hernandez, Adrian F and Green, Fiona and Green, Jennifer B and Janmohamed, Salim and D'Agostino, Ralph B and Granger, Christopher B and Jones, Michael and Jones, Nigel P and Leiter, Lawrence A and Rosenberg, Anne E and Rosenberg, Anne and Sigmon, Kristina and Sigmon, Kristina N and Somerville, Matthew and Somerville, Matthew C and Thorpe, Karl and Thorpe, Karl M and McMurray, John J V and McMurray, John J.V and Del Prato, Stefano and Califf, Robert M and Holman, Rury and DeMets, David and Riddle, Matthew and Goodman, Shaun and McGuire, Darren and Alexander, Karen and Devore, Adam and Melloni, Chiara and Patel, Chetan and Patel, Rajesh and Patel, Vickas and Patel, Prashant and Patel, Rajivkumar and Kong, David and Bloomfield, Gerald and Roe, Matthew and Tricoci, Pierluigi and Harrison, Rob and Harrison, Lindsay and Lopes, Renato and Mathews, Robin and Mehta, Anand and Mehta, Rajendra and Schuyler Jones, William and Vemulapalli, Sreekanth and Povsic, Thomas and Eapen, Zubin and Dombrowski, Keith and Kolls, Brad and Jordan, Dedrick and Ambrosy, Andrew and Greene, Deb and Greene, Stephen and Mandawat, Aditya and Shavadia, Jay and Cooper, John and Cooper, Lauren and Sharma, Abhinav and Sharma, Richa and Guimaraes, Patricia and Friedman, Daniel and Wilson, Matt and Wilson, Tim and Endsley, Patricia and Gentry, Tracy and Collier, Jeannie and Perez, Kathleen and James, Kourtnei and James, Rachel and Roush, Jennifer and Pope, Connie and Howell, Christina and Johnson, Megan and Johnson, David and Johnson, Andrew and Bailey, Matt and Cole, Joanna and Akers, Teresa and Vandyne, Beth and Thomas, Betsy and Rich, Jenny and Bartone, Susan and Beaulieu, Gail and Brown, Judith and Brown, Kim and Chau, Tuan and Christian, Tamra and Coker, Rebecca and Haddock, Trevorlyn and Jenkins, Wendy and Haque, Ghazala and Marquess, Marsha and Pesarchick, Jean and Rethaford, Renee and Stone, Allegra and Al Kawas, Firas and Anderson, Michelle and Enns, Robert and Sinay, Isaac and ... and Harmony Outcomes Comm Investigator and Harmony Outcomes committees and investigators
The Lancet, ISSN 0140-6736, 10/2018, Volume 392, Issue 10157, pp. 1519 - 1529
Glucagon-like peptide 1 receptor agonists differ in chemical structure, duration of action, and in their effects on clinical outcomes. The cardiovascular... 
MEDICINE, GENERAL & INTERNAL | RISK | METAANALYSIS | MELLITUS | SAFETY | RECEPTOR AGONISTS | Myocardial infarction | Diabetic retinopathy | Heart attacks | Peptides | Glucagon | Medical services | Clinical trials | Cardiovascular disease | Thyroid gland | Incidence | Thyroid carcinoma | Randomization | Motivation | Hemoglobin | Diuretics | Diabetes mellitus (non-insulin dependent) | Glucagon-like peptide 1 | Thyroid | Cerebral infarction | Stroke | Diabetes mellitus | Pancreatitis | Health risks | Risk reduction | Disease control | Patients | Organic chemistry | Interactive systems | Pancreatic cancer | Fatalities | Infarction | Diabetes | Cardiovascular diseases | Health risk assessment | Cancer
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3. Full Text Effect of Dutasteride on the Risk of Prostate Cancer
by Andriole, Gerald L and Bostwick, David G and Brawley, Otis W and Gomella, Leonard G and Marberger, Michael and Montorsi, Francesco and Pettaway, Curtis A and Tammela, Teuvo L and Teloken, Claudio and Tindall, Donald J and Somerville, Matthew C and Wilson, Timothy H and Fowler, Ivy L and Rittmaster, Roger S and REDUCE Study Grp and REDUCE Study Group and Sahlgrenska akademin and Göteborgs universitet and Gothenburg University and Institute of Clinical Sciences, Section for Oncology, Radiation Physics, Radiology and Urology, Department of Urology and Institutionen för kliniska vetenskaper, sektionen för onkologi, radiofysik, radiologi och urologi, Avdelningen för urologi and Sahlgrenska Academy
The New England Journal of Medicine, ISSN 0028-4793, 04/2010, Volume 362, Issue 13, pp. 1192 - 1202
Dutasteride, an inhibitor of 5α-reductase in the prostate, was tested in a large, randomized trial to determine its ability to prevent prostate cancer. Over... 
MODELING APPROACH | MEDICINE, GENERAL & INTERNAL | DESIGN | THERAPY | 5-ALPHA-REDUCTASE INHIBITOR DUTASTERIDE | SENSITIVITY | FINASTERIDE | GRADE | HYPERPLASIA | PROGRESSION | PREVENTION TRIAL | Enzyme Inhibitors - adverse effects | Prostatic Neoplasms - pathology | Prostatic Hyperplasia - pathology | Double-Blind Method | Erectile Dysfunction - chemically induced | Humans | Middle Aged | 5-alpha Reductase Inhibitors | Male | Risk | Treatment Outcome | Azasteroids - therapeutic use | Enzyme Inhibitors - therapeutic use | Prostate-Specific Antigen - blood | Azasteroids - adverse effects | Prostate - pathology | Prostatic Neoplasms - genetics | Biopsy | Protein Isoforms | Dutasteride | Aged | Prostatic Neoplasms - prevention & control | Prostatic Hyperplasia - drug therapy | Heart Failure - chemically induced | Usage | Diagnosis | Health aspects | Prostate cancer | Risk factors | Patient safety | Age | Men | Tumors | Prostate-Specific Antigen | Erectile Dysfunction | Enzyme Inhibitors | Testosterone 5-alpha-Reductase | Prostatic Hyperplasia | Life Sciences | Prostatic Neoplasms | Azasteroids | Heart Failure | Prostate | Cancer | pathology | genetics | Urologi och njurmedicin | chemically induced | drug therapy | prevention & control | blood | adverse effects | Cancer and Oncology | Urology and Nephrology | therapeutic use | Cancer och onkologi
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4. Full Text Unicompartmental Versus Total Knee Arthroplasty Database Analysis: Is There a Winner?
by Lyons, Matthew C and MacDonald, Steven J and Somerville, Lyndsay E and Naudie, Douglas D and McCalden, Richard W
Clinical Orthopaedics and Related Research, ISSN 0009-921X, 1/2012, Volume 470, Issue 1, pp. 84 - 90
TKA and unicompartmental knee arthroplasty (UKA) are both utilized to treat unicompartmental knee arthrosis. While some surgeons assume UKA provides better... 
Surgical Orthopedics | Medicine & Public Health | Sports Medicine | Surgery | Orthopedics | Conservative Orthopedics | Medicine/Public Health, general | REPLACEMENT | SURVIVORSHIP | SURGERY | SURVIVAL ANALYSIS | TERM-FOLLOW-UP | UNICONDYLAR ARTHROPLASTY | MORBID-OBESITY | OUTCOMES | 10-YEAR SURVIVAL | ORTHOPEDICS | PROSTHESIS | PRIMARY OSTEOARTHRITIS | Confidence Intervals | Arthroplasty, Replacement, Knee - adverse effects | Follow-Up Studies | Humans | Middle Aged | Male | Prosthesis Design | Recovery of Function | Knee Joint - surgery | Prosthesis Failure | Time Factors | Arthroplasty, Replacement, Knee - methods | Reoperation - statistics & numerical data | Aged, 80 and over | Female | Retrospective Studies | Osteoarthritis, Knee - surgery | Databases, Factual | Osteoarthritis, Knee - diagnosis | Kaplan-Meier Estimate | Treatment Outcome | Postoperative Care - methods | Intraoperative Care - methods | Range of Motion, Articular - physiology | Aged | Cohort Studies | Arthroplasty | Orthopedic surgery | Databases | Universities and colleges | Health aspects | Symposium | Papers Presented at the Annual Meetings of The Knee Society
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5. Full Text The Relationship between Prostate Inflammation and Lower Urinary Tract Symptoms: Examination of Baseline Data from the REDUCE Trial
by Nickel, J. Curtis and Roehrborn, Claus G and O’Leary, Michael P and Bostwick, David G and Somerville, Matthew C and Rittmaster, Roger S
European Urology, ISSN 0302-2838, 2007, Volume 54, Issue 6, pp. 1379 - 1384
Abstract Objective The ongoing REDUCE trial is a 4-yr, phase 3, placebo-controlled study to determine if daily dutasteride 0.5 mg reduces the risk of biopsy... 
Urology | Benign prostatic hyperplasia | Prostatitis | Inflammation | Lower urinary tract symptoms | THERAPY | BENIGN | UROLOGY & NEPHROLOGY | RISK | CHEMOPREVENTION | HYPERPLASIA | CANCER | Male | Prostatism - complications | Humans | Middle Aged | Prostatitis - complications | Randomized Controlled Trials as Topic
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6. Full Text A randomised, double-blind study comparing the addition of bicalutamide with or without dutasteride to GnRH analogue therapy in men with non-metastatic castrate-resistant prostate cancer
by Chu, Franklin M and Sartor, Oliver and Gomella, Leonard and Rudo, Todd and Somerville, Matthew C and Hereghty, Belinda and Manyak, Michael J
European Journal of Cancer, ISSN 0959-8049, 2015, Volume 51, Issue 12, pp. 1555 - 1569
Abstract Background Bicalutamide blocks androgen action and is frequently used in men with non-metastatic, castration-resistant prostate cancer (CRPC). By... 
Hematology, Oncology and Palliative Medicine | Prostate-specific antigen (PSA) | Castration-resistant prostate cancer (CRPC) | Dutasteride | Bicalutamide | Androgen deprivation therapy (ADT) | SURVIVAL | MANAGEMENT | TESTOSTERONE | PHASE-II | COMBINATION | CHEMOTHERAPY | ONCOLOGY | RECURRENT | RADIOTHERAPY | INHIBITOR | ANDROGEN DEPRIVATION THERAPY | Multivariate Analysis | Anilides - therapeutic use | Prospective Studies | Double-Blind Method | Humans | Middle Aged | Male | 5-alpha Reductase Inhibitors - therapeutic use | Azasteroids - therapeutic use | Prostatic Neoplasms, Castration-Resistant - drug therapy | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Antineoplastic Agents, Hormonal - therapeutic use | Tosyl Compounds - therapeutic use | Aged, 80 and over | Androgen Antagonists - therapeutic use | Aged | Gonadotropin-Releasing Hormone - therapeutic use | Prostatic Neoplasms - drug therapy | Nitriles - therapeutic use
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7. Full Text Usefulness of prostate‐specific antigen (PSA) rise as a marker of prostate cancer in men treated with dutasteride: lessons from the REDUCE study
by Marberger, Michael and Freedland, Stephen J and Andriole, Gerald L and Emberton, Mark and Pettaway, Curtis and Montorsi, Francesco and Teloken, Claudio and Rittmaster, Roger S and Somerville, Matthew C and Castro, Ramiro
BJU International, ISSN 1464-4096, 04/2012, Volume 109, Issue 8, pp. 1162 - 1169
Study Type – Prognostic (RCT) Level of Evidence 1b What's known on the subject? and What does the study add? Previous studies used the decrease in PSA after 6... 
dutasteride | performance | prostate‐specific antigen | 5α‐reductase inhibitor | REDUCE study | Dutasteride | Performance | Prostate-specific antigen | 5α-reductase inhibitor | Biopsy - methods | Predictive Value of Tests | Reproducibility of Results | Double-Blind Method | Endosonography | Follow-Up Studies | Humans | Middle Aged | Male | Treatment Outcome | Prostatic Neoplasms - diagnosis | Prostate-Specific Antigen - blood | Biomarkers, Tumor - blood | Dose-Response Relationship, Drug | Azasteroids - administration & dosage | Neoplasm Grading | Time Factors | 5-alpha Reductase Inhibitors - administration & dosage | Prostatic Neoplasms - blood | Aged | Prostatic Neoplasms - drug therapy | Prevention | Antigens | Care and treatment | Analysis | Oncology, Experimental | Research | Health aspects | Prostate cancer | Cancer | Meetings | Biopsy | Men
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8.