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American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 05/2008, Volume 294, Issue 5, pp. 2031 - 2039
This study determined the role of a slowly inactivating component of sodium current (INa), late INa, to induce delayed afterdepolarizations (DADs) and... 
Calcium overload | Action potential | Transient inward current | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | PIG VENTRICULAR MYOCYTES | HEART-FAILURE | NA+ CHANNELS | transient inward current | ANTIANGINAL AGENT | action potential | PURKINJE-FIBERS | TOXIN ATX-II | DOG HEART | RANOLAZINE | PERIPHERAL VASCULAR DISEASE | LONG QT SYNDROME | calcium overload | Up-Regulation | Calcium - metabolism | Anti-Arrhythmia Agents - pharmacology | Ryanodine Receptor Calcium Release Channel - metabolism | Sodium - metabolism | Thiourea - pharmacology | Cnidarian Venoms - pharmacology | Ranolazine | Action Potentials | Time Factors | Sodium-Calcium Exchanger - metabolism | Egtazic Acid - analogs & derivatives | Sodium Channels - metabolism | Tachycardia, Supraventricular - metabolism | Sodium-Calcium Exchanger - antagonists & inhibitors | Tetrodotoxin - pharmacology | Ryanodine - pharmacology | Acetanilides - pharmacology | Guinea Pigs | Heart Conduction System - metabolism | Heart Atria - cytology | Sodium Channel Blockers - pharmacology | Ryanodine Receptor Calcium Release Channel - drug effects | Sodium Channels - drug effects | Cardiotonic Agents - pharmacology | Chelating Agents - pharmacology | Piperazines - pharmacology | Heart Atria - metabolism | Patch-Clamp Techniques | Animals | Egtazic Acid - pharmacology | Myocytes, Cardiac - drug effects | Heart Conduction System - physiopathology | Myocytes, Cardiac - metabolism | Tachycardia, Supraventricular - physiopathology | Thiourea - analogs & derivatives | Index Medicus
Journal Article
Journal of applied physiology (Bethesda, Md. : 1985), 12/2017
Aging hearts have prolonged QT interval and are vulnerable to oxidative stress. Because the QT interval indirectly reflects the action potential duration... 
Journal Article
Journal of Applied Physiology, ISSN 8750-7587, 10/2018, Volume 125, Issue 4, pp. 1329 - 1338
Aging hearts have prolonged QT interval and are vulnerable to oxidative stress. Because the QT interval indirectly reflects the action potential duration... 
aging | action potential duration | ventricular myocytes | late sodium current | oxidative stress | SPORT SCIENCES | DOG CARDIOMYOCYTES | PHYSIOLOGY | MITOCHONDRIA | QT INTERVAL | ATRIAL-FIBRILLATION | HEART | INCREASED SUSCEPTIBILITY | HYDROGEN-PEROXIDE | CHANNELS | PROTEIN-KINASE-II
Journal Article
Circulation, ISSN 0009-7322, 11/2015, Volume 132, Issue Suppl_3 Suppl 3, pp. A17251 - A17251
Introduction Aging is associated with both a decreased tolerance to oxidative stress and an increased incidence of cardiac arrhythmias. This study examined the... 
Journal Article
Cardiovascular Research, ISSN 0008-6363, 09/2013, Volume 99, Issue 4, pp. 600 - 611
This review presents the roles of cardiac sodium channel NaV1.5 late current (late INa) in generation of arrhythmic activity. The assumption of the authors is... 
Heart | Late I | Afterpotential | Arrhythmia | Reentry | Action Potentials | Animals | Calcium - metabolism | Humans | Homeostasis | Myocytes, Cardiac - metabolism | Arrhythmias, Cardiac - etiology | NAV1.5 Voltage-Gated Sodium Channel - physiology | Sodium - metabolism | Tetrodotoxin - pharmacology | Topical Review | Late INa
Journal Article
Journal of Cardiovascular Pharmacology, ISSN 0160-2446, 08/2004, Volume 44, Issue 2, pp. 192 - 199
Journal Article
Circulation, ISSN 0009-7322, 11/2015, Volume 132, Issue Suppl_3 Suppl 3, pp. A17193 - A17193
IntroductionThe β-adrenergic agonist isoproterenol (ISO) is known to induce the arrhythmogenic transient inward current (ITi) and delayed afterdepolarization... 
Journal Article
Journal Article
Journal Article
Experimental Physiology, ISSN 0958-0670, 04/2015, Volume 100, Issue 4, pp. 399 - 409
New Findings What is the central question of this study? What are the effects of protein kinase C (PKC) and Ca2+–calmodulin‐dependent protein kinase II... 
Protein kinases | Calmodulin | Ouabain
Journal Article