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by Sims, Rebecca and van der Lee, Sven J and Naj, Adam C and Bellenguez, Céline and Badarinarayan, Nandini and Jakobsdottir, Johanna and Kunkle, Brian W and Boland, Anne and Raybould, Rachel and Bis, Joshua C and Martin, Eden R and Grenier-Boley, Benjamin and Heilmann-Heimbach, Stefanie and Chouraki, Vincent and Kuzma, Amanda B and Sleegers, Kristel and Vronskaya, Maria and Ruiz, Agustin and Graham, Robert R and Olaso, Robert and Hoffmann, Per and Grove, Megan L and Vardarajan, Badri N and Hiltunen, Mikko and Nöthen, Markus M and White, Charles C and Hamilton-Nelson, Kara L and Epelbaum, Jacques and Maier, Wolfgang and Choi, Seung-Hoan and Beecham, Gary W and Dulary, Cécile and Herms, Stefan and Smith, Albert V and Funk, Cory C and Derbois, Céline and Forstner, Andreas J and Ahmad, Shahzad and Li, Hongdong and Bacq, Delphine and Harold, Denise and Satizabal, Claudia L and Valladares, Otto and Squassina, Alessio and Thomas, Rhodri and Brody, Jennifer A and Qu, Liming and Sánchez-Juan, Pascual and Morgan, Taniesha and Wolters, Frank J and Zhao, Yi and Garcia, Florentino Sanchez and Denning, Nicola and Fornage, Myriam and Malamon, John and Naranjo, Maria Candida Deniz and Majounie, Elisa and Mosley, Thomas H and Dombroski, Beth and Wallon, David and Lupton, Michelle K and Dupuis, Josée and Whitehead, Patrice and Fratiglioni, Laura and Medway, Christopher and Jian, Xueqiu and Mukherjee, Shubhabrata and Keller, Lina and Brown, Kristelle and Lin, Honghuang and Cantwell, Laura B and Panza, Francesco and McGuinness, Bernadette and Moreno-Grau, Sonia and Burgess, Jeremy D and Solfrizzi, Vincenzo and Proitsi, Petra and Adams, Hieab H and Allen, Mariet and Seripa, Davide and Pastor, Pau and Cupples, L Adrienne and Price, Nathan D and Hannequin, Didier and Frank-García, Ana and Levy, Daniel and Chakrabarty, Paramita and Caffarra, Paolo and Giegling, Ina and Beiser, Alexa S and Giedraitis, Vilmantas and Hampel, Harald and Garcia, Melissa E and Wang, Xue and Lannfelt, Lars and Mecocci, Patrizia and Eiriksdottir, Gudny and Crane, Paul K and Pasquier, Florence and Boccardi, Virginia and ... and Medicinska fakulteten and Geriatrik and Medicinska och farmaceutiska vetenskapsområdet and Uppsala universitet and Institutionen för folkhälso- och vårdvetenskap
Nature Genetics, ISSN 1061-4036, 2017, Volume 49, Issue 9, p. 1373
Journal Article
Surgical neurology international, ISSN 2229-5097, 2018, Volume 9, Issue 1, pp. 144 - 144
Ependymomas are rare neuroepithelial tumors thought to arise from radial glial precursor cells lining the walls of the ventricles and central canal of the... 
Studies | Identification | Nuclear magnetic resonance--NMR | Brain cancer | Classification | Tumors
Journal Article
JAMA Neurology, ISSN 2168-6149, 11/2015, Volume 72, Issue 11, pp. 1313 - 1323
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 2010, Volume 6, Issue 4, pp. S83 - S83
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 2014, Volume 10, Issue 4, pp. P423 - P423
Journal Article
Journal Article
Journal of Bone and Joint Surgery, ISSN 0021-9355, 2010, Volume 92, Issue 2, pp. 396 - 403
Background Protective antiself response to nervous system injury has been reported to be mediated by a T-cell subpopulation that can recognize self-antigens.... 
Orthopedics
Journal Article
The Lancet Neurology, ISSN 1474-4422, 08/2008, Volume 7, Issue 8, p. 704
  The threat of a looming pandemic of dementia in elderly people highlights the compelling need for the development and validation of biomarkers that can be... 
Medical imaging | Pathogenesis | Laboratories | Neuropathology | Cognitive ability | Clinical trials | Gene expression | Risk factors | Proteins | Older people | Biomarkers | Alzheimers disease | Age | Dementia | Chronic illnesses
Journal Article
by Wang, Li-San and Naj, Adam C and Graham, Robert R and Crane, Paul K and Kunkle, Brian W and Cruchaga, Carlos and Murcia, Josue D. Gonzalez and Cannon-Albright, Lisa and Baldwin, Clinton T and Zetterberg, Henrik and Blennow, Kaj and Kukull, Walter A and Faber, Kelley M and Schupf, Nicole and Norton, Maria C and Tschanz, JoAnn T and Munger, Ronald G and Corcoran, Christopher D and Rogaeva, Ekaterina and Lin, Chiao-Feng and Dombroski, Beth A and Cantwell, Laura B and Partch, Amanda and Valladares, Otto and Hakonarson, Hakon and St George-Hyslop, Peter and Green, Robert C and Goate, Alison M and Foroud, Tatiana M and Carney, Regina M and Larson, Eric B and Behrens, Timothy W and Kauwe, John S. K and Haines, Jonathan L and Farrer, Lindsay A and Pericak-Vance, Margaret A and Mayeux, Richard and Schellenberg, Gerard D and Albert, Marilyn S and Albin, Roger L and Apostolova, Liana G and Arnold, Steven E and Barber, Robert and Barmada, M. Michael and Barnes, Lisa L and Beach, Thomas G and Becker, James T and Beecham, Gary W and Beekly, Duane and Bennett, David A and Bigio, Eileen H and Bird, Thomas D and Blacker, Deborah and Boeve, Bradley F and Bowen, James D and Boxer, Adam and Burke, James R and Buxbaum, Joseph D and Cairns, Nigel J and Cao, Chuanhai and Carlson, Chris S and Carroll, Steven L and Chui, Helena C and Clark, David G and Cribbs, David H and Crocco, Elizabeth A and DeCarli, Charles and DeKosky, Steven T and Demirci, F. Yesim and Dick, Malcolm and Dickson, Dennis W and Duara, Ranjan and Ertekin-Taner, Nilufer and Fallon, Kenneth B and Farlow, Martin R and Ferris, Steven and Frosch, Matthew P and Galasko, Douglas R and Ganguli, Mary and Gearing, Marla and Geschwind, Daniel H and Ghetti, Bernardino and Gilbert, John R and Glass, Jonathan D and Graff-Radford, Neill R and Growdon, John H and Hamilton, Ronald L and Hamilton-Nelson, Kara L and Harrell, Lindy E and Head, Elizabeth and Honig, Lawrence S and Hulette, Christine M and Hyman, Bradley T and Jarvik, Gail P and Jicha, Gregory A and Jin, Lee-Way and Jun, Gyungah and Kamboh, M. Ilyas and Karydas, Anna and Kaye, Jeffrey A and ... and Alzheimer's Dis Genetics and Natl Inst Aging-Late-Onset and Alzheimer's Disease Genetics Consortium and National Institute on Aging-Late-Onset Alzheimer’s Disease (NIA-LOAD) Family Study and Sahlgrenska akademin and Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi and Göteborgs universitet and Gothenburg University and Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry and Sahlgrenska Academy
JAMA Neurology, ISSN 2168-6149, 02/2015, Volume 72, Issue 2, pp. 209 - 216
IMPORTANCE: Recently, a rare variant in the amyloid precursor protein gene (APP) was described in a population from Iceland. This variant, in which alanine is... 
ALLELE | GENE | MUTATION | RISK | APOE | POLYMORPHISM | ASSOCIATION | ONSET | CLINICAL NEUROLOGY | APOLIPOPROTEIN-E | AGE | United States - epidemiology | Humans | Genotype | Male | Sweden - epidemiology | Case-Control Studies | Protective Factors | Amyloid beta-Protein Precursor - genetics | Pedigree | Aged, 80 and over | Alzheimer Disease - epidemiology | Female | Aged | Alzheimer Disease - genetics | Neurosciences | Neurovetenskaper
Journal Article
by Brainstorm Consortium and Anttila, Verneri and Bulik-Sullivan, Brendan and Finucane, Hilary K and Walters, Raymond K and Bras, Jose and Duncan, Laramie and Escott-Price, Valentina and Falcone, Guido J and Gormley, Padhraig and Malik, Rainer and Patsopoulos, Nikolaos A and Ripke, Stephan and Wei, Zhi and Yu, Dongmei and Lee, Phil H and Turley, Patrick and Grenier-Boley, Benjamin and Chouraki, Vincent and Kamatani, Yoichiro and Berr, Claudine and Letenneur, Luc and Hannequin, Didier and Amouyel, Philippe and Boland, Anne and Deleuze, Jean-François and Duron, Emmanuelle and Vardarajan, Badri N and Reitz, Christiane and Goate, Alison M and Huentelman, Matthew J and Kamboh, M Ilyas and Larson, Eric B and Rogaeva, Ekaterina and St George-Hyslop, Peter and Hakonarson, Hakon and Kukull, Walter A and Farrer, Lindsay A and Barnes, Lisa L and Beach, Thomas G and Demirci, F Yesim and Head, Elizabeth and Hulette, Christine M and Jicha, Gregory A and Kauwe, John SK and Kaye, Jeffrey A and Leverenz, James B and Levey, Allan I and Lieberman, Andrew P and Pankratz, Vernon S and Poon, Wayne W and Quinn, Joseph F and Saykin, Andrew J and Schneider, Lon S and Smith, Amanda G and Sonnen, Joshua A and Stern, Robert A and Van Deerlin, Vivianna M and Van Eldik, Linda J and Harold, Denise and Russo, Giancarlo and Rubinsztein, David Chaim and Bayer, Anthony and Tsolaki, Magda and Proitsi, Petra and Fox, Nick C and Hampel, Harald and Owen, Michael J and Mead, Simon and Passmore, Peter and Morgan, Kevin and Nöthen, Markus M and Rossor, Martin and Lupton, Michelle K and Hoffmann, Per and Kornhuber, Johannes and Lawlor, Brian and McQuillin, Andrew and Al-Chalabi, Ammar and Bis, Joshua C and Ruiz, Agustin and Boada, Mercè and Seshadri, Sudha and Beiser, Alexa and Rice, Kenneth and van der Lee, Sven J and De Jager, Philip L and Geschwind, Daniel H and Riemenschneider, Matthias and Riedel-Heller, Steffi and Rotter, Jerome I and Ransmayr, Gerhard and Hyman, Bradley T and Cruchaga, Carlos and Alegret, Montserrat and Winsvold, Bendik and Palta, Priit and Farh, Kai-How and Cuenca-Leon, Ester and Furlotte, Nicholas and ...
Science (New York, N.Y.), ISSN 0036-8075, 2018, Volume 360, Issue 6395, p. 1313
Disorders of the brain can exhibit considerable epidemiological comorbidity and share symptoms, provoking debate about their etiologic overlap. We quantified... 
Genetic Variation | Brainstorm Consortium | Phenotype | Genome-Wide Association Study | Quantitative Trait, Heritable | Humans | Risk Factors | Mental Disorders | Brain Diseases
Journal Article
Journal of neuropathology and experimental neurology, ISSN 0022-3069, 10/2011, Volume 70, Issue 10, pp. 832 - 840
Individuals with antemortem preservation of cognition who show autopsy evidence of at least moderate Alzheimer disease (AD) pathology suggest the possibility... 
Adult Changes in Thought Study | Nun Study | Alzheimer disease | preclinical | presymptomatic | dementia | brain reserve
Journal Article
Journal of the Neurological Sciences, ISSN 0022-510X, 2010, Volume 296, Issue 1, pp. 22 - 29
Abstract An X-linked myopathy was recently associated with mutations in the four-and-a-half-LIM domains 1 ( FHL1 ) gene. We identified a family with late... 
Neurology | X-linked myopathy | Scapuloperoneal | Neurogenetics | Muscular dystrophy | FHL1 | Genetic diagnosis | ELECTROSTATIC ENERGIES | DOMINANT | BINDING PROTEIN | NEUROSCIENCES | CLINICAL NEUROLOGY | GENE | REDUCING BODY MYOPATHY | Immunohistochemistry | Homeodomain Proteins - metabolism | Humans | Middle Aged | Child, Preschool | Infant | Male | Muscle, Skeletal - metabolism | Intracellular Signaling Peptides and Proteins - metabolism | Mutation, Missense - genetics | Young Adult | Muscular Atrophy, Spinal - genetics | Mutation - physiology | Gait Disorders, Neurologic - physiopathology | Muscle Proteins - metabolism | Gait Disorders, Neurologic - pathology | Adult | Female | Genetic Diseases, X-Linked - genetics | Genetic Linkage - genetics | Child | Intracellular Signaling Peptides and Proteins - genetics | Muscular Atrophy, Spinal - physiopathology | Genetic Diseases, X-Linked - physiopathology | LIM Domain Proteins | Models, Molecular | Exons - genetics | Mutation - genetics | Reverse Transcriptase Polymerase Chain Reaction | Muscular Atrophy, Spinal - pathology | Homeodomain Proteins - genetics | Muscle Proteins - genetics | Phenotype | Pedigree | Adolescent | Genetic Diseases, X-Linked - pathology | Polymorphism, Single Nucleotide - genetics | LIM-Homeodomain Proteins | Protein Conformation | Aged | Transcription Factors | Ubiquitin | Family | Genetic aspects | Protein binding | muscular dystrophy | genetic diagnosis | neurogenetics | scapuloperoneal
Journal Article
Journal of Neuro-Ophthalmology, ISSN 1070-8022, 09/2015, Volume 35, Issue 3, pp. 315 - 318
Five years previously, a 52-year-old man developed diplopia requiring prism glasses. This was followed by imbalance resulting in frequent backward falls as... 
Journal Article
Journal Article