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animals (8) 8
humans (8) 8
male (8) 8
mice, inbred c57bl (7) 7
disease models, animal (6) 6
mice (6) 6
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carotid arteries - pathology (2) 2
carotid artery injuries - drug therapy (2) 2
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carotid artery, common - pathology (2) 2
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VASA-EUROPEAN JOURNAL OF VASCULAR MEDICINE, ISSN 0301-1526, 07/2019, Volume 48, Issue 4, pp. 371 - 372
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2017, Volume 12, Issue 9, p. e0184888
Background The novel nonsteroidal mineralocorticoid receptor (MR) antagonist finerenone holds promise to be safe and efficient in the treatment of patients... 
CHRONIC HEART-FAILURE | LEFT-VENTRICULAR DYSFUNCTION | MYOCARDIAL-INFARCTION | MULTIDISCIPLINARY SCIENCES | BAY 94-8862 | ALDOSTERONE | MICE | CHRONIC KIDNEY-DISEASE | EPLERENONE | HYPERPLASIA | CORONARY-ARTERY-DISEASE | Human Umbilical Vein Endothelial Cells | Aldosterone - toxicity | Neovascularization, Physiologic - drug effects | Muscle, Smooth, Vascular - metabolism | Apoptosis - drug effects | Humans | Carotid Artery Injuries - drug therapy | Male | Carotid Artery Injuries - etiology | Leukocytes - immunology | Mineralocorticoid Receptor Antagonists - pharmacology | Carotid Artery Injuries - pathology | Disease Models, Animal | Leukocytes - cytology | Cell Line | Mice, Inbred C57BL | Muscle, Smooth, Vascular - cytology | Mineralocorticoid Receptor Antagonists - therapeutic use | Neointima - prevention & control | Animals | Naphthyridines - therapeutic use | Neointima - pathology | Carotid Arteries - pathology | Cell Proliferation - drug effects | Mice | Leukocytes - metabolism | Naphthyridines - pharmacology | Cell proliferation | Flow cytometry | Femur | Femoral artery | Heart attacks | Syngeneic grafts | Smooth muscle | Cardiovascular disease | Aldosterone | Remodeling | Electric wire | Caspase-3 | Medical schools | Cell growth | Rodents | Attenuation | Carotid artery | Cardiology | Heart diseases | Stents | Heart failure | Mortality | Blood vessels | Caspase | Cardiomyocytes | Studies | Cytometry | Injury prevention | Coronary vessels | Renal failure | In vivo methods and tests | Kidney diseases | In vitro methods and tests | Apoptosis | Kidney transplantation
Journal Article
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 11227 - 8
Telomere length is a marker of biological aging. Short leukocyte telomere length has been associated with various conditions including cardiovascular... 
HEART | DIAGNOSIS | GENETICS | MULTIDISCIPLINARY SCIENCES | BONE-MARROW | MITOCHONDRIA | DISEASE | Polymerase chain reaction | Heart | Telomeres | Yeast | Cardiomyopathy | Peripheral blood | Aging | Ventricle | Chromosomes
Journal Article
Amino Acids, ISSN 0939-4451, 06/2017, Volume 49, Issue 6, pp. 1111 - 1121
Asymmetric dimethylarginine (ADMA) and l-homoarginine (hArg) are l-arginine (Arg) metabolites derived from different pathways. Protein arginine... 
Plasma | GC–MS | Guanidino amino acids | Nitric oxide | AGAT | Cardiovascular disease | Aortic atherosclerosis and distensibility | BIOCHEMISTRY & MOLECULAR BIOLOGY | PLASMA HOMOARGININE | ASYMMETRIC DIMETHYLARGININE ADMA | RENAL-TRANSPLANT RECIPIENTS | GC-MS | ALL-CAUSE MORTALITY | CREATINE SUPPLEMENTATION | SUBSTRATE-SPECIFICITY | GUANIDINO COMPOUNDS | NITRIC-OXIDE | CORONARY-ARTERY-DISEASE | CARDIOVASCULAR RISK | Nitric Oxide - blood | Vascular Remodeling | Aorta - diagnostic imaging | Stroke - diagnostic imaging | Humans | Middle Aged | Male | Homoarginine - blood | Aorta - metabolism | Arginine - analogs & derivatives | Atherosclerosis - blood | Stroke - blood | Atherosclerosis - diagnostic imaging | Endothelium, Vascular - diagnostic imaging | Endothelium, Vascular - metabolism | Arginine - blood | Ultrasonography | Female | Stroke (Disease) | Proteins | Evaluation | Metabolites | Arginine | Proteolysis | Vasodilators | Atherosclerosis | Physiological aspects | Stroke patients | Mass spectrometry | Creatinine | Stroke | Echocardiography | Transient ischemic attack | Kidneys | Media | Glycine amidinotransferase | Mass spectroscopy | Nitrates | Nitrite | Arteries | Nitric-oxide synthase | Gas chromatography | Nitrate | Ischemia | Arteriosclerosis | N-Methyltransferase | Aorta | Cardiovascular diseases | Kidney transplantation | Index Medicus
Journal Article
Cardiovascular research, ISSN 0008-6363, 03/2019, Volume 115, Issue 12, pp. 1804 - 1810
Delayed re-endothelialization after balloon angioplasty in patients with coronary or peripheral artery disease impairs vascular healing and leads to neointimal... 
Vascular injury | Original | RNA-binding protein Rbm38 | Re-endothelialization
Journal Article
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 02/2016, Volume 36, Issue 2, pp. 317 - 327
Journal Article
Cardiovascular Research, ISSN 0008-6363, 11/2017, Volume 113, Issue 13, pp. 1653 - 1663
Aims Adventitial cells have been suggested to contribute to neointima formation, but the functional relevance and the responsible signalling pathways are... 
Fibroblasts | Smoothened | Neointima formation | Sonic Hedgehog | PROGENITOR CELLS | MIGRATION | CARDIAC & CARDIOVASCULAR SYSTEMS | INJURY | PHENOTYPE | PROLIFERATION | IL-6 | CHEMOATTRACTANT | SMOOTH-MUSCLE-CELLS | EXPRESSION | Carotid Arteries - metabolism | Femoral Artery - pathology | Cell Proliferation | Muscle, Smooth, Vascular - metabolism | Myocytes, Smooth Muscle - pathology | Hedgehog Proteins - metabolism | Male | Smoothened Receptor - metabolism | Adventitia - metabolism | Vascular System Injuries - pathology | Neointima | Time Factors | Myocytes, Smooth Muscle - drug effects | Proto-Oncogene Proteins c-sis - pharmacology | Myocytes, Smooth Muscle - metabolism | Smoothened Receptor - antagonists & inhibitors | Carotid Artery Injuries - metabolism | Carotid Artery Injuries - pathology | Disease Models, Animal | Fibroblasts - metabolism | Muscle, Smooth, Vascular - drug effects | Cyclic AMP-Dependent Protein Kinases - metabolism | Cytokines - metabolism | Paracrine Communication | Signal Transduction | Mice, Inbred C57BL | Cells, Cultured | Adventitia - drug effects | Fibroblasts - pathology | Vascular System Injuries - metabolism | Muscle, Smooth, Vascular - injuries | Muscle, Smooth, Vascular - pathology | Animals | Fibroblasts - drug effects | Anilides - pharmacology | Femoral Artery - metabolism | Adventitia - pathology | Carotid Arteries - pathology | Pyridines - pharmacology | Cell Movement
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 10/2004, Volume 279, Issue 44, pp. 45433 - 45440
S -nitrosothiols transport nitric oxide in vivo , and so-called transnitrosation reactions ( i.e. the transfer of the nitroso function from nitrosothiol to... 
TRYPTOPHAN | NITROXYL ANION | ACID | MECHANISM | PEROXYNITRITE | ENDOTHELIUM | SERUM-ALBUMIN | NITROSATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | NITRIC-OXIDE | CHEMISTRY | Sulfhydryl Compounds - metabolism | Cysteine - metabolism | Nitrosation | S-Nitrosothiols - metabolism | Glutathione - metabolism | Tryptophan - metabolism
Journal Article
Circulation, ISSN 0009-7322, 12/2016, Volume 134, Issue 24, pp. 1973 - 1990
BACKGROUND:The transcription factor GATA2 orchestrates the expression of many endothelial-specific genes, illustrating its crucial importance for endothelial... 
microRNAs | MIRN126 microRNA, human | reendothelialization | GATA2 transcription factor | angiogenesis inducing agents | MIRN221 microRNA, human | Human Umbilical Vein Endothelial Cells | MicroRNAs - therapeutic use | MicroRNAs - antagonists & inhibitors | Nanoparticles - chemistry | Humans | Male | MicroRNAs - metabolism | Intracellular Signaling Peptides and Proteins - metabolism | Forkhead Box Protein O3 - genetics | RNA Interference | Carotid Artery Diseases - pathology | Base Sequence | Forkhead Box Protein O3 - antagonists & inhibitors | Lentivirus - genetics | Membrane Proteins - metabolism | 3' Untranslated Regions | Intracellular Signaling Peptides and Proteins - genetics | GATA2 Transcription Factor - genetics | Disease Models, Animal | Membrane Proteins - genetics | Mice, Inbred C57BL | Genetic Vectors - metabolism | Forkhead Box Protein O3 - metabolism | Genetic Vectors - genetics | Mice, Knockout | Carotid Artery Diseases - therapy | GATA2 Transcription Factor - antagonists & inhibitors | Intercellular Adhesion Molecule-1 - metabolism | Sequence Alignment | Animals | Intercellular Adhesion Molecule-1 - chemistry | Membrane Proteins - chemistry | Intracellular Signaling Peptides and Proteins - chemistry | Intercellular Adhesion Molecule-1 - genetics | GATA2 Transcription Factor - metabolism | Mice | Antagomirs - metabolism | RNA, Small Interfering - metabolism | Blood circulation disorders | Care and treatment | Transcription factors | MicroRNA | Research | Diagnosis
Journal Article
DMW - Deutsche Medizinische Wochenschrift, ISSN 0012-0472, 02/2016, Volume 141, Issue 3, pp. e38 - e38
Journal Article
DMW - Deutsche Medizinische Wochenschrift, ISSN 0012-0472, 02/2016, Volume 141, Issue 3, pp. 211 - 214
Zusammenfassung Anamnese und klinischer Befund: Bei neurologischer Symptomatik infolge eines thrombotischen Verschlusses der A. basilaris erfolgte bei einem 78... 
Fachwissen | Aneurysma spurium | transradial angiography | ultrasound-guided manual compression | hemodynamic monitoring | Pseudoaneurysm | radial artery
Journal Article
Thrombosis and haemostasis, ISSN 0340-6245, 2014, Volume 112, Issue 6, pp. 1264 - 1276
Maladaptive remodelling of the arterial wall after mechanical injury (e. g. angioplasty) is characterised by inflammation, neointima formation and media... 
Reendothelialisation | Arterial remodelling | Inflammation | Leukocytes | MK2 | CELLS | INFLAMMATORY RESPONSES | ATHEROSCLEROSIS | NEOINTIMA FORMATION | VASCULAR INJURY | P38 | inflammation | MONOCYTE RECRUITMENT | P-SELECTIN | leukocytes | PERIPHERAL VASCULAR DISEASE | MICE | HEMATOLOGY | reendothelialisation | EXPRESSION | Inflammation - pathology | Protein-Serine-Threonine Kinases - deficiency | Vascular Remodeling | Cell Proliferation | Muscle, Smooth, Vascular - metabolism | Endothelium, Vascular - injuries | Hyperplasia | Receptors, LDL | Myocytes, Smooth Muscle - pathology | Wound Healing | Endothelium, Vascular - enzymology | Intracellular Signaling Peptides and Proteins - deficiency | Neointima | Carotid Artery Injuries - genetics | Chemokine CCL2 - metabolism | Chemokine CCL5 - metabolism | Intracellular Signaling Peptides and Proteins - genetics | Myocytes, Smooth Muscle - metabolism | Carotid Artery Injuries - pathology | Disease Models, Animal | Re-Epithelialization | Mice, Inbred C57BL | Cells, Cultured | Protein-Serine-Threonine Kinases - genetics | Cell Adhesion | Mice, Knockout | Muscle, Smooth, Vascular - pathology | Animals | Carotid Artery Injuries - enzymology | Carotid Artery, Common - enzymology | Carotid Artery, Common - pathology | Endothelium, Vascular - pathology | Hypercholesterolemia - complications | Inflammation - prevention & control | Hypercholesterolemia - genetics | Hypercholesterolemia - metabolism | Inflammation - enzymology | Leukocytes - metabolism | Cell Movement
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 09/2013, Volume 33, Issue 9, pp. 2097 - 2104
OBJECTIVE—Reendothelialization after vascular injury (ie, balloon angioplasty or stent implantation) is clinically extremely relevant to promote vascular... 
neointima formation | cytokines | endothelial growth factors | vascular system injuries | toll-like receptors | MALP-2 | CELLS | ATHEROSCLEROSIS | ADAPTER MOLECULES | PANCREATIC-CARCINOMA | ANGIOPLASTY | SIGNALING PATHWAY | MOUSE MODEL | PERIPHERAL VASCULAR DISEASE | MICE | HEMATOLOGY | EXPRESSION | Toll-Like Receptor 2 - agonists | Vascular System Injuries - immunology | Lipopeptides - pharmacology | Humans | Myocytes, Smooth Muscle - pathology | Carotid Artery Injuries - drug therapy | Male | Vascular System Injuries - drug therapy | Vascular System Injuries - pathology | Neointima | Time Factors | Carotid Artery, Common - immunology | Platelet Aggregation - drug effects | Myocytes, Smooth Muscle - drug effects | Myocytes, Smooth Muscle - metabolism | Wound Healing - drug effects | Carotid Artery Injuries - metabolism | Carotid Artery Injuries - pathology | Disease Models, Animal | Toll-Like Receptor 6 - metabolism | Cytokines - metabolism | Enzyme-Linked Immunosorbent Assay | Carotid Artery, Common - metabolism | Endothelial Cells - metabolism | Mice, Inbred C57BL | Cells, Cultured | Toll-Like Receptor 2 - metabolism | Endothelial Cells - immunology | Vascular System Injuries - metabolism | Animals | MAP Kinase Signaling System - drug effects | Carotid Artery, Common - drug effects | Myocytes, Smooth Muscle - immunology | Protein Array Analysis | Carotid Artery, Common - pathology | Carotid Artery Injuries - immunology | Cell Proliferation - drug effects | Mice | Endothelial Cells - pathology | Toll-Like Receptor 6 - agonists | Endothelial Cells - drug effects | Mitogen-Activated Protein Kinases - metabolism
Journal Article
Medicina Fluminensis, ISSN 1847-6864, 2014, Volume 50, Issue 1, pp. 7 - 20
Journal Article
Thrombosis and Haemostasis, ISSN 0340-6245, 2014, Volume 111, Issue 12, pp. 1264 - 1276
Summary Maladaptive remodelling of the arterial wall after mechanical injury (e. g. angioplasty) is characterised by inflammation, neointima formation and... 
Cardiovascular Biology and Cell Signalling
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 10/2004, Volume 279, Issue 44, pp. 45433 - 45440
Journal Article