Articles

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (26) 26
immunology (21) 21
animals (20) 20
mice (16) 16
article (14) 14
asthma (14) 14
female (11) 11
expression (10) 10
inflammation (10) 10
humans (9) 9
t cells (9) 9
abridged index medicus (8) 8
cytokines (8) 8
mice, inbred c57bl (8) 8
rodents (8) 8
allergy and immunology (7) 7
in-vivo (7) 7
mice, knockout (7) 7
asthma - immunology (6) 6
cd4-positive t-lymphocytes - immunology (6) 6
disease models, animal (6) 6
flow cytometry (6) 6
induction (6) 6
lung - pathology (6) 6
mice, transgenic (6) 6
pathogenesis (6) 6
receptor (6) 6
respiratory tract diseases (6) 6
signal transduction - immunology (6) 6
tgf-beta (6) 6
activation (5) 5
allergy (5) 5
antigens (5) 5
gene expression (5) 5
ilc2 (5) 5
immunity (5) 5
ligands (5) 5
lung - immunology (5) 5
lymphoid cells (5) 5
ox40-ox40 ligand interaction (5) 5
signal transduction (5) 5
t cell receptors (5) 5
airway hyperreactivity (4) 4
allergens - immunology (4) 4
allergies (4) 4
analysis (4) 4
asthma - pathology (4) 4
cells, cultured (4) 4
chemistry (4) 4
clonal expansion (4) 4
cytokines - immunology (4) 4
dendritic cells (4) 4
homeostasis (4) 4
human necessities (4) 4
hygiene (4) 4
lymphocyte activation - immunology (4) 4
medical or veterinary science (4) 4
metallurgy (4) 4
mice, inbred balb c (4) 4
multidisciplinary sciences (4) 4
organic chemistry (4) 4
peptides (4) 4
preparations for medical, dental, or toilet purposes (4) 4
proteins (4) 4
research (4) 4
respiratory system (4) 4
specific therapeutic activity of chemical compounds ormedicinal preparations (4) 4
t-lymphocyte subsets - immunology (4) 4
tumor necrosis factor (4) 4
arthritis (3) 3
autoimmune diseases (3) 3
autophagy (3) 3
bronchoalveolar lavage fluid - immunology (3) 3
cd4-positive t-lymphocytes - metabolism (3) 3
cell line, tumor (3) 3
chronic disease (3) 3
costimulation (3) 3
immune system (3) 3
immune-response (3) 3
immunity, innate (3) 3
immunologic memory (3) 3
inflammation - immunology (3) 3
lung inflammation (3) 3
lungs (3) 3
lymphocytes (3) 3
lymphocytes - immunology (3) 3
lymphocytes t (3) 3
male (3) 3
medical colleges (3) 3
medicine, research & experimental (3) 3
microbiology (3) 3
ox40 (3) 3
phosphorylation (3) 3
receptors, ox40 - metabolism (3) 3
regulatory t-cells (3) 3
responses (3) 3
signal transduction - genetics (3) 3
survival (3) 3
t-lymphocytes - immunology (3) 3
t-lymphocytes, regulatory - immunology (3) 3
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text Type 2 innate lymphoid cell suppression by regulatory T cells attenuates airway hyperreactivity and requires inducible T-cell costimulator–inducible T-cell costimulator ligand interaction
by Rigas, Diamanda, MS and Lewis, Gavin, PhD and Aron, Jennifer L., MD and Wang, Bowen, MS and Banie, Homayon, BS and Sankaranarayanan, Ishwarya, MS and Galle-Treger, Lauriane, PhD and Maazi, Hadi, DVM, PhD and Lo, Richard, BS and Freeman, Gordon J., PhD and Sharpe, Arlene H., MD, PhD and Soroosh, Pejman, PhD and Akbari, Omid, PhD
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2016, Volume 139, Issue 5, pp. 1468 - 1477.e2
Background Atopic diseases, including asthma, exacerbate type 2 immune responses and involve a number of immune cell types, including regulatory T (Treg) cells... 
Allergy and Immunology | inducible T-cell costimulator | inducible T-cell costimulator ligand | Type 2 innate lymphoid cells | airway hyperreactivity | regulatory T cells | IL-5 | asthma | IL-13 | ALLERGIC INFLAMMATION | HOMEOSTASIS | TOLERANCE | INDUCTION | IMMUNOLOGY | regulatory T cells | ALLERGY | ICOS | Coculture Techniques | Humans | Cells, Cultured | Bronchoalveolar Lavage Fluid - immunology | Mice, Transgenic | Immunity, Innate | Mice, SCID | Animals | Lymphocytes - immunology | Asthma - immunology | Mice, Inbred NOD | Cytokines - immunology | Disease Models, Animal | T cells | Medical colleges | Asthma | Genetic research | Microbiology | Gene expression | Lymphoid cells | Immunoglobulins | Immune response | Severe combined immunodeficiency | Cytokines | Control methods | Immunoregulation | Hypersensitivity | Antibodies | Lymphocytes T | Inflammation | Interleukin 13 | Atopy | Respiratory tract | Interleukin 5 | Lymphocytes | Rodents | ICOS protein | Interleukin 10 | Respiratory tract diseases | Ligands | Activation analysis
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text ICOS:ICOS-Ligand Interaction Is Required for Type 2 Innate Lymphoid Cell Function, Homeostasis, and Induction of Airway Hyperreactivity
by Maazi, Hadi and Patel, Nisheel and Sankaranarayanan, Ishwarya and Suzuki, Yuzo and Rigas, Diamanda and Soroosh, Pejman and Freeman, Gordon J and Sharpe, Arlene H and Akbari, Omid
Immunity, ISSN 1074-7613, 03/2015, Volume 42, Issue 3, pp. 538 - 551
Allergic asthma is caused by Th2-cell-type cytokines in response to allergen exposure. Type 2 innate lymphoid cells (ILC2s) are a newly identified subset of... 
HUMAN INTERLEUKIN-5 | ADAPTIVE IMMUNITY | RESPONSES | TH2 DIFFERENTIATION | TRANSCRIPTION FACTOR GATA3 | REGULATORY T-CELLS | ALLERGIC LUNG INFLAMMATION | RECEPTOR | IMMUNOLOGY | MOLECULE ICOS | EXPRESSION | Respiratory System - pathology | Humans | STAT5 Transcription Factor - immunology | Homeostasis | Interleukin-13 - immunology | Interleukin-5 - genetics | Interleukins - genetics | STAT5 Transcription Factor - genetics | Interleukin-13 - genetics | Interleukin-2 - immunology | Lymphocytes - immunology | Interleukins - immunology | Asthma - immunology | Inducible T-Cell Co-Stimulator Protein - genetics | Female | Inducible T-Cell Co-Stimulator Protein - immunology | Respiratory System - immunology | Inducible T-Cell Co-Stimulator Ligand - immunology | Signal Transduction | Interleukin-33 | Gene Expression Regulation | Mice, Transgenic | Immunity, Innate | Asthma - genetics | Interleukin-5 - immunology | Interleukin-2 - genetics | Lymphocytes - pathology | Animals | Inducible T-Cell Co-Stimulator Ligand - genetics | Asthma - pathology | Allergens | T cells | Asthma | Immunology | Compliance | Pathogenesis | Lymphocytes | Rodents | Cloning | Ligands | Software | Histology | Gene expression | Experiments
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text Lack of autophagy induces steroid-resistant airway inflammation
by Suzuki, Yuzo, MD, PhD and Maazi, Hadi, DVM, PhD and Sankaranarayanan, Ishwarya, MS and Lam, Jonathan, PhD and Khoo, Bryant, BSc and Soroosh, Pejman, PhD and Barbers, Richard G., MD and James Ou, J.-H., PhD and Jung, Jae U., PhD and Akbari, Omid, PhD
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2015, Volume 137, Issue 5, pp. 1382 - 1389.e9
Background Neutrophilic corticosteroid-resistant asthma accounts for a significant proportion of asthma; however, little is known about the mechanisms that... 
Allergy and Immunology | asthma | corticosteroid-resistance asthma | Autophagy | neutrophilic asthma | lung inflammation | HYPERREACTIVITY | IMMUNITY | SEVERE ASTHMA | ALLERGEN | INDUCTION | IMMUNOLOGY | SELECTIVE AUTOPHAGY | CELL-DEATH | ALLERGY | INFECTION | CYSTIC-FIBROSIS | Cell Count | Mice, Inbred C57BL | Bronchoalveolar Lavage Fluid - immunology | Autophagy-Related Protein 5 - genetics | Lung - cytology | Asthma - drug therapy | Mice, Knockout | Dexamethasone - therapeutic use | Animals | Asthma - immunology | Anti-Inflammatory Agents - therapeutic use | Female | Bronchoalveolar Lavage Fluid - cytology | Mice, Inbred BALB C | Drug Resistance | Lung - immunology | Cytokines - immunology | Pyroglyphidae - immunology | Medical colleges | Corticosteroids | Asthma | Inflammation | Dendritic cells | Analysis | Flow cytometry | Statistical analysis | Cytokines | Pathogenesis | Neutrophils | Gene expression | Lungs | Microscopy | Lymphocytes | Rodents | Bone marrow | Methods
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text The significance of OX40 and OX40L to T‐cell biology and immune disease
by Croft, Michael and So, Takanori and Duan, Wei and Soroosh, Pejman
Immunological Reviews, ISSN 0105-2896, 05/2009, Volume 229, Issue 1, pp. 173 - 191
OX40 (CD134) and its binding partner, OX40L (CD252), are members of the tumor necrosis factor receptor/tumor necrosis factor superfamily and are expressed on... 
OX40 | immune disease | CD4 | costimulation | OX40L | CD8 | Treg | T cells | Costimulation | Immune disease | OX40-OX40 LIGAND INTERACTION | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | PLASMACYTOID-DENDRITIC-CELLS | IMMUNOLOGY | VERSUS-HOST-DISEASE | ENHANCES ANTITUMOR IMMUNITY | GROWTH-FACTOR RECEPTOR | TUMOR-NECROSIS-FACTOR | CLONAL EXPANSION | IN-VIVO | NF-KAPPA-B | T-Lymphocyte Subsets - immunology | Signal Transduction - immunology | Lymphocyte Activation - immunology | Neoplasms - therapy | Animals | Neoplasms - immunology | Humans | Immunotherapy | Inflammation - immunology | CD40 Antigens - immunology | CD40 Ligand - immunology | T-Lymphocytes, Regulatory - immunology | Antigens
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text Th9 and allergic disease
by Soroosh, Pejman and Doherty, Taylor A
Immunology, ISSN 0019-2805, 08/2009, Volume 127, Issue 4, pp. 450 - 458
Summary Helper CD4+ T‐cell subsets have improved our understanding of adaptive immunity in humans and in animal models of disease. These include T helper type... 
allergy | asthma | IL‐9 | TGF‐beta | airway remodeling | Th2 | Allergy | TGF-beta | Airway remodeling | IL-9 | Asthma | INTERLEUKIN-9 MESSENGER-RNA | BRONCHIAL HYPERRESPONSIVENESS | MAST-CELLS | IMMUNOLOGY | GROWTH-FACTOR-BETA | IL-9 EXPRESSION | EPITHELIAL-CELLS | REGULATORY T-CELLS | AIRWAY SMOOTH-MUSCLE | TRANSCRIPTION FACTOR | Interleukin-9 - biosynthesis | T-Lymphocyte Subsets - immunology | Animals | Humans | Asthma - immunology | Hypersensitivity - immunology | Mice | Th2 Cells - immunology | Asthma - pathology | Disease Models, Animal | Chronic diseases | Bone morphogenetic proteins | T cells | Analysis | Review articles
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text Programmed cell death ligand 2 regulates TH9 differentiation and induction of chronic airway hyperreactivity
by Kerzerho, Jerome and Maazi, Hadi and Speak, Anneliese O and Szely, Natacha and Lombardi, Vincent and Khoo, Bryant and Geryak, Stacey and Lam, Jonathan and Soroosh, Pejman and Van Snick, Jacques and Akbari, Omid
The Journal of Allergy and Clinical Immunology, ISSN 0091-6749, 04/2013, Volume 131, Issue 4, pp. 1048 - 1057.e2
Asthma is defined as a chronic inflammatory disease of the airways; however, the underlying physiologic and immunologic processes are not fully understood. The... 
TH9 | costimulation | TGF-β | chronic airway hyperreactivity | Aspergillus fumigatus | Asthma | programmed cell death ligand 2 | T-Lymphocyte Subsets - immunology | Interleukin-1alpha - immunology | Bronchial Hyperreactivity - immunology | Bronchial Hyperreactivity - genetics | Allergens - immunology | Antibodies - immunology | Bronchial Hyperreactivity - metabolism | Female | Lung - metabolism | Disease Models, Animal | Adaptive Immunity | Severity of Illness Index | Transforming Growth Factor beta - immunology | Lung - pathology | Programmed Cell Death 1 Ligand 2 Protein - genetics | Gene Expression Regulation | Programmed Cell Death 1 Ligand 2 Protein - immunology | Cell Differentiation - immunology | Bronchial Hyperreactivity - pathology | Animals | T-Lymphocyte Subsets - pathology | Aspergillus fumigatus - immunology | Lymphocyte Count | Mice | Mice, Inbred BALB C | Chronic Disease | Interleukin-9 - immunology | Lung - immunology | Mortality | Rodents | Allergies | Immune system
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text Impairment of Autophagy in Pulmonary CD11c+ Cells Induces Corticosteroid-Unresponsive Airway Hyperreactivity
by Maazi, Hadi, Dr and Suzuki, Yuzo, Dr and Khoo, Bryant, Mr and Soroosh, Pejman, Dr and Jung, Jae U., Dr and Akbari, Omid, Prof
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2016, Volume 137, Issue 2, pp. AB410 - AB410
  Adoptive transfer of bone-marrow derived CD11c+ cells from ATG5-/- but not WT mice is sufficient to mediate Th17-dependent neutrophilic asthma in WT... 
Allergy and Immunology | Corticosteroids | Inflammation | Pathogenesis | Autophagy | Rodents | Asthma
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text OX40–OX40 Ligand Interaction in T-Cell-Mediated Immunity and Immunopathology
by Ishii, Naoto and Takahashi, Takeshi and Soroosh, Pejman and Sugamura, Kazuo
2010, Advances in Immunology, ISBN 9780123813022, Volume 105, Issue C, 36
T-cell activation is mediated not only by antigen stimulation through T-cell receptors but also by costimulatory signals through costimulatory molecules. Among... 
DENDRITIC-CELLS | SYSTEMIC-LUPUS-ERYTHEMATOSUS | TGF-BETA | B-CELL | COSTIMULATORY SIGNALS | OX40 LIGAND | TRANSCRIPTION FACTOR FOXP3 | IN-VIVO | IMMUNOLOGICAL SELF-TOLERANCE | VASCULAR ENDOTHELIAL-CELLS | IMMUNOLOGY | Signal Transduction | OX40 Ligand - metabolism | Humans | Inflammation - immunology | CD4-Positive T-Lymphocytes - immunology | Receptors, OX40 - metabolism | Animals | Immunologic Memory | T-Lymphocytes - immunology | Mice | CD8-Positive T-Lymphocytes - immunology | Transforming Growth Factor beta - metabolism | Interleukin-7 - metabolism | Signal transduction | Immunology | Cellular biology | Molecular biology | Binding sites
Book Chapter
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text Oxysterols are agonist ligands of RORγt and drive Th17 cell differentiation
by Pejman Soroosh and Jiejun Wu and Xiaohua Xue and Jiao Song and Steven W. Sutton and Marciano Sablad and Jingxue Yu and Marina I. Nelen and Xuejun Liu and Glenda Castro and Rosa Luna and Shelby Crawford and Homayon Banie and Rose A. Dandridge and Xiaohu Deng and Anton Bittner and Chester Kuei and Mandana Tootoonchi and Natasha Rozenkrants and Krystal Herman and Jingjin Gao and Xia V. Yang and Kacey Sachen and Karen Ngo and Wai-Ping Fung-Leung and Steven Nguyen and Aimee de Leon-Tabaldo and Jonathan Blevitt and Yan Zhang and Maxwell D. Cummings and Tadimeti Rao and Neelakandha S. Mani and Changlu Liu and Murray McKinnon and Marcos E. Milla and Anne M. Fourie and Siquan Sun
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2014, Volume 111, Issue 33, pp. 12163 - 12168
The RAR-related orphan receptor gamma t (RORγt) is a nuclear receptor required for generating IL-17-producing CD4⁺ Th17 T cells, which are essential in host... 
T lymphocytes | Receptors | Sterols | Splenocytes | Agonists | Ligands | Cultured cells | Cellular differentiation | Cholesterols | Lymph nodes | MIGRATION | EBI2 | MULTIDISCIPLINARY SCIENCES | ASSAYS | ALPHA | BILE-ACID BIOSYNTHESIS | BINDING | STEROL 27-HYDROXYLASE | Sterols - pharmacology | Sterols - metabolism | Animals | Cholestanetriol 26-Monooxygenase - metabolism | Nuclear Receptor Subfamily 1, Group F, Member 3 - agonists | Nuclear Receptor Subfamily 1, Group F, Member 3 - metabolism | Th17 Cells - cytology | Cell Differentiation | Mice | Interleukin-17 - biosynthesis | Biological Sciences
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
10. Full Text Inflammasome-Mediated Disease Animal Models Reveal Roles for Innate but Not Adaptive Immunity
by Brydges, Susannah D and Mueller, James L and McGeough, Matthew D and Pena, Carla A and Misaghi, Amirhossein and Gandhi, Chhavi and Putnam, Chris D and Boyle, David L and Firestein, Gary S and Horner, Anthony A and Soroosh, Pejman and Watford, Wendy T and O'Shea, John J and Kastner, Daniel L and Hoffman, Hal M
Immunity, ISSN 1074-7613, 06/2009, Volume 30, Issue 6, pp. 875 - 887
NLRP3 nucleates the inflammasome, a protein complex responsible for cleavage of prointerleukin-1β (IL-1β) to its active form. Mutations in the gene cause the... 
MOLIMMUNO | CELLIMMUNO | ACTIVATION | PROTEIN | INTERLEUKIN-1 RECEPTOR ANTAGONIST | MUCKLE-WELLS-SYNDROME | MICE | COLD AUTOINFLAMMATORY SYNDROME | IMMUNOLOGY | CIAS1 MUTATIONS | CELL | NALP3 INFLAMMASOME | PYRIN | Immunity, Active | Cytokines - metabolism | NLR Family, Pyrin Domain-Containing 3 Protein | Immunity, Innate - genetics | Interleukin-1beta - immunology | Inflammation - immunology | Mutation - genetics | Mutation - immunology | Gene Knock-In Techniques | Carrier Proteins - genetics | Animals | B-Lymphocytes - immunology | Carrier Proteins - metabolism | T-Lymphocytes - metabolism | Interleukin-1beta - metabolism | Mice, Mutant Strains | Inflammation - genetics | T-Lymphocytes - immunology | Mice | Interleukin-18 | B-Lymphocytes - metabolism | Carrier Proteins - immunology | Cytokines - immunology | Disease Models, Animal | Analysis | Oncology, Experimental | Skin diseases | Arthritis | Research | T cells | Cancer | Disease | Pathogenesis | Stem cells | Immune system
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights