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Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 1319 - 1319
Abstract RUNX1 is a transcription factor essential during definitive hematopoiesis. Germline mutations in RUNX1 results in a disorder called Familial Platelet... 
Journal Article
Molecular Diagnosis and Therapy, ISSN 1177-1062, 02/2013, Volume 17, Issue 1, pp. 31 - 47
Prevalent as an acquired abnormality in cancer, the role of tumor protein p53 (TP53) as a germline mutation continues to evolve. The clinical impact of a... 
BREAST-CANCER | MAMMOGRAPHIC DENSITY | GENETICS & HEREDITY | GERMLINE MUTATIONS | MUTANT P53 | MYELOGENOUS LEUKEMIA | CHRONIC LYMPHOCYTIC-LEUKEMIA | PHARMACOLOGY & PHARMACY | PREDICTIVE-VALUE | CHOROID-PLEXUS TUMORS | SOFT-TISSUE-SARCOMA | OLIGONUCLEOTIDE OLP53 | Breast cancer | Mutation | Genes | Tumors
Journal Article
Blood, ISSN 0006-4971, 12/2016, Volume 128, Issue 22, pp. 2693 - 2693
Abstract Acute myeloid leukemia (AML) has a higher incidence and death rate than all other types of adult-onset acute leukemia in the USA, thus requiring a... 
Journal Article
Journal Article
Blood, ISSN 0006-4971, 12/2014, Volume 124, Issue 21, pp. 278 - 278
Abstract Background: DS-AML patients (<4 years of age), have favorable outcomes compared to non-DS AML patients. However, DS patients experience significant... 
Journal Article
Pediatric Neurology, ISSN 0887-8994, 05/2012, Volume 46, Issue 5, p. 336
Journal Article
Journal Article
BLOOD, ISSN 0006-4971, 06/2017, Volume 129, Issue 25, pp. 3304 - 3313
Patients with myeloid leukemia of Down syndrome (ML-DS) have favorable event-free survival (EFS), but experience significant treatment-related morbidity and... 
MULTICENTER TRIAL | POPULATION | INFECTIOUS COMPLICATIONS | ACUTE MEGAKARYOBLASTIC LEUKEMIA | HIGH CURE RATE | MUTATIONS | HEMATOLOGY | GATA1 | EXPRESSION | MEGAKARYOCYTIC LEUKEMIA | CHEMOTHERAPY | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Cytarabine - therapeutic use | Humans | Antibiotics, Antineoplastic - adverse effects | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Child, Preschool | Infant | Male | Cytarabine - adverse effects | Leukemia, Myeloid, Acute - complications | Antimetabolites, Antineoplastic - administration & dosage | Neoplasm, Residual - diagnosis | Down Syndrome - complications | Leukemia, Myeloid, Acute - drug therapy | Female | Cytogenetic Analysis | Daunorubicin - administration & dosage | Myelodysplastic Syndromes - drug therapy | Daunorubicin - therapeutic use | Treatment Outcome | Myelodysplastic Syndromes - complications | Cytarabine - administration & dosage | Neoplasm, Residual - genetics | Daunorubicin - adverse effects | Antibiotics, Antineoplastic - administration & dosage | Disease-Free Survival | Antimetabolites, Antineoplastic - therapeutic use | Antibiotics, Antineoplastic - therapeutic use | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Antimetabolites, Antineoplastic - adverse effects | Down Syndrome - genetics | Myelodysplastic Syndromes - genetics | Leukemia, Myeloid, Acute - genetics | Index Medicus | Abridged Index Medicus
Journal Article
Blood, ISSN 0006-4971, 06/2017, Volume 129, Issue 25, pp. 3304 - 3313
Publisher's Note: There is an Inside Blood Commentary on this article in this issue. 
100 | Clinical Trials and Observations
Journal Article
Journal Article
American Journal of Physiology, ISSN 0193-1849, 03/2008, Volume 294, Issue 3, p. E630
  Leptin regulates energy balance and glucose homeostasis, at least in part, via activation of receptors in the arcuate nucleus of the hypothalamus located in... 
Brain | Peptides | Body fat | Neurons | Endocrine system | Glucose | Insulin
Journal Article
American Journal of Physiology: Endocrinology and Metabolism, ISSN 0193-1849, 03/2008, Volume 294, Issue 3, pp. E630 - E639
Leptin regulates energy balance and glucose homeostasis, at least in part, via activation of receptors in the arcuate nucleus of the hypothalamus located in... 
Journal Article
Journal Article
Blood, ISSN 0006-4971, 08/2006, Volume 108, Issue 4, pp. 1165 - 1173
Journal Article
The American Journal of Physiology, ISSN 0002-9513, 03/2008, Volume 294, Issue 3, p. E630
Leptin regulates energy balance and glucose homeostasis, at least in part, via activation of receptors in the arcuate nucleus of the hypothalamus located in... 
Physiological aspects | Homeostasis | Polypeptides | Research | Leptin
Journal Article
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