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1. Full Text The Alzheimer's disease-associated amyloid β-protein is an antimicrobial peptide
by Soscia, Stephanie J and Kirby, James E and Washicosky, Kevin J and Tucker, Stephanie M and Ingelsson, Martin and Hyman, Bradley and Burton, Mark A and Goldstein, Lee E and Duong, Scott and Tanzi, Rudolph E and Moir, Robert D and Medicinska fakulteten and Geriatrik and Medicinska och farmaceutiska vetenskapsområdet and Uppsala universitet and Institutionen för folkhälso- och vårdvetenskap
PLoS ONE, ISSN 1932-6203, 03/2010, Volume 5, Issue 3, p. e9505
Background: The amyloid beta-protein (A beta) is believed to be the key mediator of Alzheimer's disease (AD) pathology. A beta is most often characterized as... 
PRECURSOR-LIKE PROTEIN | MULTIDISCIPLINARY SCIENCES | A-BETA | CENTRAL-NERVOUS-SYSTEM | ALAMAR-BLUE | BACTERIAL | BINDING | BRAIN | APOLIPOPROTEIN-E | INNATE IMMUNITY | CELL-DEATH | Amyloid beta-Peptides - physiology | Cell Survival | Humans | Antimicrobial Cationic Peptides - pharmacology | Recombinant Proteins - chemistry | Inflammation | Candida albicans - metabolism | Immunity, Innate | Microbial Sensitivity Tests | Alzheimer Disease - metabolism | Amyloid beta-Peptides - metabolism | Brain - pathology | Environment | Ligands | Xanthenes - pharmacology | Oxazines - pharmacology | Brain | Neurosciences | Antimicrobial activity | Peptides | Laboratories | Trafficking | Antibodies | Smooth muscle | Antiinfectives and antibacterials | Receptors | Microorganisms | Aging | Physiology | Alzheimer's disease | Immune system | Bacterial infections | Engineering schools | Neurodegenerative diseases | Neutrophils | Antimicrobial agents | Permeability | Environmental stress | Pathology | Neurology | Brain research | Hospitals | Antibiotics | β-Amyloid | In vivo methods and tests | Alzheimers disease | Apoptosis | Medical and Health Sciences | MEDICINE | Medicin och hälsovetenskap | MEDICIN
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2. Full Text Combination Antiretroviral Therapy and the Risk of Myocardial Infarction
by Friis-Moller, N and Sabin, CA and Weber, R and Monforte, AD and El-Sa, WM and Reiss, P and Thiebaut, R and Morfeldt, L and De Wit, S and Pradier, C and Calvo, G and Law, MG and Kirk, O and Phillips, AN and Lundgren, JD and Monteforte, AD and Bartsch, G and Dabis, F and Houyez, F and Loeliger, E and Tressler, R and Weller, I and Sjol, A and Sawitz, A and Rickenbach, M and Pezzotti, P and Krum, E and Meester, R and Lavignolle, V and Mulder, J and van der Meer, J and Sprenger, HG and Koopmans, P and Borleffs, J and Crane, LR and Johnson, MA and Martinelli, C and The Data Collection on Adverse Events of Anti-HIV Drugs (DAD) Study Group and DAD Study Grp and Data Collection on Adverse Events of Anti-HIV Drugs (DAD) Study Group
The New England Journal of Medicine, ISSN 0028-4793, 11/2003, Volume 349, Issue 21, pp. 1993 - 2003
This prospective, observational study assessed the risk of myocardial infarction among 23,468 HIV-1–infected patients in relation to treatment with combination... 
MONICA PROJECT | HEART-DISEASE | ADULTS | LIPODYSTROPHY | HIV-1-INFECTED PATIENTS | EVENT RATES | ASSOCIATION | UMCG Approved | CORONARY-ARTERY-DISEASE | PROTEASE INHIBITORS | HIV-INFECTED PATIENTS | MEDICINE, GENERAL & INTERNAL | HIV-1 | Myocardial Infarction - chemically induced | Anti-Retroviral Agents - therapeutic use | Myocardial Infarction - epidemiology | Prospective Studies | Follow-Up Studies | Humans | Middle Aged | Risk Factors | Anti-Retroviral Agents - adverse effects | Male | CD4 Lymphocyte Count | Incidence | Regression Analysis | HIV Infections - complications | Adult | Female | HIV Infections - drug therapy | Poisson Distribution | Drug Therapy, Combination | Adverse and side effects | Antiviral agents | Anti-HIV agents | Heart attack | Risk factors | Clinical trials | Therapy | Heart attacks | Metabolism | Human immunodeficiency virus--HIV | Older people
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3. Full Text Combination Antiretroviral Therapy and the Risk of Myocardial Infarction: The Data Collection on Adverse Events of Anti-HIV Drugs (DAD) Study Group
by Friis-Møller, Nina and Sabin, Caroline A and Weber, Rainer and d'Arminio Monforte, Antonella and El-Sadr, Wafaa M and Reiss, Peter and Thiébaut, Rodolphe and Morfeldt, Linda and De Wit, Stephane and Pradier, Christian and Calvo, Gonzalo and Law, Matthew G and Kirk, Ole and Phillips, Andrew N and Lundgren, Jens D and Bartsch, G and Dabis, F and Houyez, F and Loeliger, E and Tressler, R and Weller, I and Sjøl, A and Sawitz, A and Rickenbach, M and Pezzotti, P and Krum, E and Meester, R and Lavignolle, V and Sundström, A and Poll, B and Fontas, E and Torres, F and Petoumenos, K and Kjær, J and Hammer, S and Neaton, J and Sjøl, A and de Wolf, F and van der Ven, E and Zaheri, S and Van Valkengoed, I and Bronsveld, W and Weigel, H and Brinkman, K and Frissen, P and ten Veen, J and Hillebrand, M and van Dam, P and Schieveld, S and Mulder, J and van Gorp, E and Meenhorst, P and van Eeden, A and Danner, S and Claessen, F and Perenboom, R and Eeftinck Schattenkerk, J.K and Godfried, M and Lange, J and Lowe, S and van der Meer, J and Nellen, F and Pogany, K and van der Poll, T and Prins, J and Ruys, T and van der Valk, M and Wit, F and Richter, C and van Leusen, R and Vriesendorp, R and Jeurissen, F and Kauffmann, R and Koger, E and Bravenboer, B and ten Napel, C and Sprenger, H.G and Law, G and ten Kate, R.W and Leemhuis, M and Kroon, F and Schippers, E and Schrey, G and van der Geest, S and Verbon, A and Koopmans, P and Keuter, M and Telgt, D and van der Ven, A and van der Ende, M and Gyssens, I and de Marie, S and Juttmann, J and van der Heul, C and Schneider, M and Borleffs, J and Hoepelman, I and Jaspers, C and Matute, A and Schurink, C and ...
New England Journal of Medicine, ISSN 0028-4793, 11/2003, Volume 349, Issue 21, pp. 1993 - 2003
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4. Full Text HIV-induced immunodeficiency and mortality from AIDS-defining and non-AIDS-defining malignancies
by D'Arminio Monforte, Antonella and Abrams, Donald and Pradier, Christian and Weber, Rainer and Reiss, Peter and Bonnet, Fabrice and Kirk, Ole and Law, Matthew and de Wit, Stephane and Friis-Møller, Nina and Phillips, Anew N and Sabin, Caroline A and Lundgren, Jens D and Collins, S and Loeliger, E and Tressler, R and Weller, I and Friis-Møller, N and Worm, S. W and Sabin, C. A and Sjøl, A and Lundgren, J. D and Sawitz, A and Rickenbach, M and Pezzotti, P and Krum, E and Gras, L and Balestre, E and Sundström, A and Poll, B and Fontas, E and Torres, F and Petoumenos, K and Kjaer, J and de Wolf, F and Zaheri, S and Bronsveld, W and Hillebrand-Haverkort, M. E and Prins, J. M and Bos, J. C and Eeftinck Schattenkerk, J. K. M and Geerlings, S. E and Godfried, M. H and Lange, J. M. A and van der Meer, J. T. M and Nellen, F. J. B and van der Poll, T and van der Valk, M and van Vugt, M and Wit, F. W. M. N and Data Collect Adverse Events and Data Collection on Adverse Events of Anti-HIV Drugs (D:A:D) Study Group
AIDS (London, England), ISSN 0269-9370, 2008, Volume 22, Issue 16, pp. 2143 - 2153
OBJECTIVE: To evaluate deaths from AIDS-defining malignancies (ADM) and non-AIDS-defining malignancies (nADM) in the D:A:D Study and to investigate the... 
D:A:D study | Non-AIDS-defining malignancies | AIDS-defining malignancies | HIV infection | Mortality | UNITED-STATES | CELLS | INFECTIOUS DISEASES | VIRUS | DEATH | IMMUNOLOGY | LIVER-DISEASE | non-AIDS-defining malignancies | VIROLOGY | HEPATITIS | ERA | ACTIVE ANTIRETROVIRAL THERAPY | mortality | CANCER-RISK | INFECTED PATIENTS | Age Factors | Drug Administration Schedule | Humans | Middle Aged | Neoplasms - mortality | Male | CD4 Lymphocyte Count | Lymphoma, AIDS-Related - immunology | Anti-HIV Agents - administration & dosage | Young Adult | HIV Infections - immunology | Lymphoma, AIDS-Related - mortality | Neoplasms - virology | Epidemiologic Methods | Neoplasms - immunology | HIV Infections - complications | Sex Factors | Adult | Female | HIV Infections - drug therapy | HIV Infections - mortality | Aged | Immunocompromised Host | Homosexuality, Male - statistics & numerical data
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5. Full Text Variable Impact on Mortality of AIDS-Defining Events Diagnosed during Combination Antiretroviral Therapy: Not All AIDS-Defining Conditions Are Created Equal
by Mocroft, Amanda and Sterne, Jonathan A. C and Egger, Matthias and May, Margaret and Grabar, Sophie and Furrer, Hansjakob and Sabin, Caroline and Fatkenheuer, Gerd and Justice, Amy and Reiss, Peter and D'Arminio Monforte, Antonella and Gill, John and Hogg, Robert and Bonnet, Fabrice and Kitahata, Mari and Staszewski, Schlomo and Casabona, Jordi and Harris, Ross and Saag, Michael and Chêne, Geneviève and Costagliola, Dominique and Dabis, François and de Wolf, Frank and Ledergerber, Bruno and Phillips, Anew and Weller, Ian and Sterne, Jonathan and Abgrall, S and Barin, F and Bentata, M and Billaud, E and Boué, F and Gras, L. A and Prins, J. M and Godfried, M. H and Lange, J. M. A and van der Meer, J. T. M and Nellen, F. J. B and van der Poll, T and Vermeulen, J. N and van Vugt, M and Wit, F. W. M. N and Kuijpers, T. W and Pajkrt, D and Scherpbier, H. J and Back, N. K. T and Berkhout, B and Jurriaans, S and Zaaijer, H. L and van Kan, H. J. M and Antiretroviral Therapy Cohort Collaboration (ART-CC) and Antiretroviral Therapy Cohort Collaboration (ART‐CC)
Clinical Infectious Diseases, ISSN 1058-4838, 4/2009, Volume 48, Issue 8, pp. 1138 - 1151
Background. The extent to which mortality differs following individual acquired immunodeficiency syndrome (AIDS)-defining events (ADEs) has not been assessed... 
HIV/AIDS | Antiretrovirals | HIV | Physicians | Mortality | Pulmonary tuberculosis | AIDS | Death | Epidemiology | Viral load | Carts | Prognosis | Humans | Proportional Hazards Models | AIDS-Related Opportunistic Infections - diagnosis | Male | Acquired Immunodeficiency Syndrome - drug therapy | Lymphoma, AIDS-Related - diagnosis | Lymphoma, AIDS-Related - mortality | AIDS-Related Opportunistic Infections - mortality | Acquired Immunodeficiency Syndrome - mortality | Acquired Immunodeficiency Syndrome - diagnosis | Adult | Anti-HIV Agents - therapeutic use | Female | Acquired Immunodeficiency Syndrome - complications | Drug Therapy, Combination | Cohort Studies | Research | Demographic aspects | United States | Patient outcomes | AIDS (Disease)
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6. Full Text Incidence of Tuberculosis among HIV-Infected Patients Receiving Highly Active Antiretroviral Therapy in Europe and North America
by The Antiretroviral Therapy Cohort Collaboration and Antiretroviral Therapy Cohort Coll and Antiretroviral Therapy Cohort Collaboration and The Antiretroviral Therapy Cohort Collaboration
Clinical Infectious Diseases, ISSN 1058-4838, 12/2005, Volume 41, Issue 12, pp. 1772 - 1782
Background. We obtained estimates of the incidence of tuberculosis (TB) among patients receiving HAART and identified determinants of the incidence. Methods.... 
HIV/AIDS | Highly active antiretroviral therapy | Antiretrovirals | Tuberculosis | HIV | Mycobacterium tuberculosis | RNA | Latent tuberculosis | AIDS | Infections | Virology | IMPACT | INITIATION | IMMUNE-RESPONSES | IMMUNOLOGICAL RESPONSE | OPPORTUNISTIC INFECTIONS | RISK | COHORT | EPIDEMIC | RECONSTITUTION | INFECTIOUS DISEASES | MICROBIOLOGY | IMMUNOLOGY | Antiretroviral Therapy, Highly Active | Tuberculosis - epidemiology | Humans | HIV Infections - complications | Tuberculosis - complications | Europe - epidemiology | Adult | Female | HIV Infections - drug therapy | Male | North America - epidemiology | Incidence | HIV patients | Health aspects | Risk factors
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7. Full Text Predictors of trend in CD4-positive T-cell count and mortality among HIV-1-infected individuals with virological failure to all three antiretroviral-drug classes
by Ledergerber, Bruno and PLATO Collaboration
The Lancet, ISSN 0140-6736, 2004, Volume 364, Issue 9428, pp. 51 - 62
Treatment strategies for patients in whom HIV replication is not suppressed after exposure to several drug classes remain unclear. We aimed to assess the... 
VIRAL LOAD | THERAPY | HAART REGIMEN | BLIND CONTROLLED-TRIAL | HIV-INFECTED INDIVIDUALS | COHORT | HUMAN-IMMUNODEFICIENCY-VIRUS | INHIBITOR | UMCG Approved | CLINICAL PROGRESSION | DISEASE PROGRESSION | MEDICINE, GENERAL & INTERNAL | HIV-1 | Anti-Retroviral Agents - therapeutic use | Follow-Up Studies | HIV Infections - virology | Humans | Middle Aged | Risk Factors | Proportional Hazards Models | Male | CD4 Lymphocyte Count | HIV Protease Inhibitors - therapeutic use | Viral Load | HIV Infections - immunology | Treatment Failure | Adult | Female | HIV Infections - drug therapy | HIV Infections - mortality | Reverse Transcriptase Inhibitors - therapeutic use | Cohort Studies | Antiviral agents | HIV patients | Dosage and administration | Research | Drug therapy | Drug tolerance | Measurement | Patient outcomes | T cells | Health aspects | HIV infection | T cell receptors | Regression analysis | Human immunodeficiency virus--HIV | Mortality | Medical treatment | Clinical outcomes
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8. Full Text Intracerebral streptozotocin model of type 3 diabetes: Relevance to sporadic Alzheimer's disease
by Lester-Coll, N and Rivera, EJ and Soscia, SJ and Doiron, K and Wands, JR and De la Monte, SM
JOURNAL OF ALZHEIMERS DISEASE, ISSN 1387-2877, 03/2006, Volume 9, Issue 1, pp. 13 - 33
The cascade of Alzheimer's disease (AD) neurodegeneration is associated with persistent oxidative stress, mitochondrial dysfunction, impaired energy... 
OXIDATIVE STRESS | insulin | INSULIN-DEGRADING ENZYME | GLYCOGEN-SYNTHASE KINASE-3 | IN-SITU HYBRIDIZATION | AMYLOID PRECURSOR PROTEIN | APOLIPOPROTEIN-E GENOTYPE | NEUROSCIENCES | SIGNAL-TRANSDUCTION | streptozotocin | GLUCOSE-METABOLISM | RT-PCR | growth factor receptors | glycogen synthase kinase | CENTRAL-NERVOUS-SYSTEM | diabetes | Alzheimer's disease | GROWTH-FACTOR EXPRESSION | Islets of Langerhans - pathology | Humans | Rats, Long-Evans | Injections, Intraventricular | Rats | Streptozocin - administration & dosage | Alzheimer Disease - pathology | Brain - metabolism | Insulin - metabolism | Animals | Islets of Langerhans - metabolism | Alzheimer Disease - metabolism | Brain - pathology | Diabetes Mellitus, Experimental - pathology | Receptor, Insulin - metabolism | Diabetes Mellitus, Experimental - metabolism | Disease Models, Animal
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9. Full Text Factors associated with first- versus second-generation long-acting antipsychotics prescribed under ordinary clinical practice in Italy
by Ostuzzi, Giovanni and Mazzi, Maria Angela and Terlizzi, Samira and Bertolini, Federico and Aguglia, Andrea and Bartoli, Francesco and Bortolaso, Paola and Callegari, Camilla and Caroleo, Mariarita and Carrà, Giuseppe and Corbo, Mariangela and D'Agostino, Armando and Gastaldon, Chiara and Lucii, Claudio and Magliocco, Fabio and Martinotti, Giovanni and Nosé, Michela and Ostinelli, Edoardo Giuseppe and Papola, Davide and Piccinelli, Marco Piero and Piccoli, Alberto and Purgato, Marianna and Tabacchi, Tommaso and Turrini, Giulia and Ruggeri, Mirella and Barbui, Corrado and De Fazio, Pasquale and Raffaele, Gaetano and Chirico, Margherita and Cavallotti, Simone and Bolognesi, Simone and Debolini, Sara and Pierantozzi, Elisa and Fargnoli, Francesco and Del Zanna, Maria and Giannini, Alessandra and Luccarelli, Livia and De Capua, Alberto and Annese, Pasqua Maria and Cerretini, Massimiliano and Tozzi, Fior-Ella and Magnani, Nadia and Cardamone, Giuseppe and Bardicchia, Francesco and Facchi, Edvige and Soscia, Federica and Zotos, Spyridon and Biancosino, Bruno and Zonta, Filippo and Pompei, Francesco and Zizolfi, Daniele and Poloni, Nicola and Ielmini, Marta and Caselli, Ivano and Giana, Edoardo and Buzzi, Aldo and Diurni, Marcello and Milano, Anna and Sani, Emanuele and Calzolari, Roberta and Piccinelli, Marco and Cazzamalli, Sara and Alberini, Gabrio and Piantanida, Silvia and Costantini, Chiara and Paronelli, Chiara and Di Caro, Angela and Moretti, Valentina and Gozzi, Mauro and D'Ippolito, Chiara and Barbanti, Silva Veronica and Alessandro, Papalini and Campese, Ornella and Fiori, Federica and Lorusso, Marco and Di Capro, Lucia and Viceconte, Daniela and Mancini, Valerio and Suraniti, Francesco and Signorelli, Maria Salvina and Rossi, Eugenio and Lupoli, Pasqualino and Menchetti, Marco and Terzi, Laura and Boso, Marianna and Risaro, Paolo and De Paoli, Giuseppe and Catania, Cristina and Tarricone, Ilaria and Caretto, Valentina and Storbini, Viviana and Emiliani, Roberta and Balzarro, Beatrice and Nava, Roberto and Bono, Adele and Provenzi, Milena and Brambilla, Giulia and Aspesi, Flora and Tremolada, Martina and Castagna, Gloria and ... and STAR Network Investigators and the STAR Network Investigators
PLoS ONE, ISSN 1932-6203, 08/2018, Volume 13, Issue 8, p. e0201371
Background For many years, long-acting intramuscular (LAI) antipsychotics have been prescribed predominantly to chronic and severe patients, as a last resort... 
1ST EPISODE | COMPARATIVE EFFICACY | NEGATIVE SYMPTOMS | MULTIDISCIPLINARY SCIENCES | INJECTABLE ANTIPSYCHOTICS | SCHIZOPHRENIA | DEPOT ANTIPSYCHOTICS | INJECTIONS | PATIENT | ORAL ANTIPSYCHOTICS | ATTITUDES | Schizophrenia | Bipolar disorder | Usage | Care and treatment | Prescription writing | Antipsychotic drugs | Health sciences | Neurosciences | Substance abuse treatment | Neuroleptics | Mental disorders | Comorbidity | Mental health | Systematic review | Regression analysis | Aripiprazole | Males | Metabolism | Patients | Training | Psychotropic drugs | Hospitals | Maternal & child health | Surgery | Diagnosis | Risperidone | Psychiatry | Drug use
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