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Nature, ISSN 0028-0836, 07/2012, Volume 487, Issue 7408, pp. 505 - 509
Mutationally activated kinases define a clinically validated class of targets for cancer drug therapy(1). However, the efficacy of kinase inhibitors in... 
CELL LUNG-CANCER | SURVIVAL | HETEROGENEITY | ACTIVATION | RECEPTOR TYROSINE KINASES | THERAPY | MET AMPLIFICATION | MULTIDISCIPLINARY SCIENCES | ACQUIRED-RESISTANCE | SENSITIVITY | TUMOR-CELLS | Receptor, ErbB-2 - genetics | Humans | Receptor, ErbB-2 - metabolism | Melanoma - enzymology | Phosphatidylinositol 3-Kinases - metabolism | Hepatocyte Growth Factor - pharmacology | Breast Neoplasms - metabolism | Melanoma - genetics | Female | Indoles - pharmacology | Antineoplastic Agents - pharmacology | Cell Survival - drug effects | Melanoma - pathology | Receptor Protein-Tyrosine Kinases - metabolism | Sulfonamides - pharmacology | Breast Neoplasms - drug therapy | Hepatocyte Growth Factor - metabolism | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Breast Neoplasms - genetics | Signal Transduction - drug effects | Breast Neoplasms - pathology | Proto-Oncogene Proteins B-raf - genetics | Melanoma - drug therapy | Cell Line, Tumor | Ligands | Protein Kinase Inhibitors - pharmacology | Quinazolines - pharmacology | Drug Resistance, Neoplasm - drug effects | Mitogen-Activated Protein Kinases - metabolism | Antimitotic agents | Physiological aspects | Antineoplastic agents | Growth factors | Health aspects | Phosphotransferases | Substance abuse treatment | Epidermal growth factor | Rodents | Biomarkers | Breast cancer | Insulin-like growth factors | Kinases | Drug resistance | Tumors | Index Medicus
Journal Article
Journal of Translational Medicine, ISSN 1479-5876, 01/2015, Volume 13, Issue Suppl 1, pp. 1 - 1
Journal Article
Journal Article
Journal of the National Cancer Institute, ISSN 0027-8874, 06/2016, Volume 108, Issue 6, pp. djv406 - djv406
Journal Article
Cancer Research, ISSN 0008-5472, 01/2015, Volume 75, Issue 1, pp. 181 - 193
Journal Article
Journal Article
JOURNAL OF TRANSLATIONAL MEDICINE, ISSN 1479-5876, 06/2013, Volume 11, Issue 1, pp. 137 - 137
Journal Article
Molecular Cancer Therapeutics, ISSN 1535-7163, 12/2015, Volume 14, Issue 12 Supplement 2, pp. PR06 - PR06
Journal Article
Cancer research, ISSN 0008-5472, 1/2015, Volume 75, Issue 1, pp. 181 - 193
Therapeutics that induce cancer cell senescence can block cell proliferation and promote immune rejection. However, the risk of tumor relapse due to senescence... 
Journal Article
The American Journal of Human Genetics, ISSN 0002-9297, 2010, Volume 86, Issue 1, pp. 88 - 92
Journal Article
Journal of the National Comprehensive Cancer Network : JNCCN, 04/2016, Volume 14, Issue 4, p. 450
This selection from the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Melanoma focuses on adjuvant therapy and treatment of in-transit... 
Melanoma - therapy | Melanoma - diagnosis | Humans
Journal Article
American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting, ISSN 1548-8748, 2012, p. 524
Recent advances in the understanding of the melanoma biology and tumor immunology have yielded new treatment strategies for patients with advanced melanoma.... 
Journal Article