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1. Full Text A sensory neuron–expressed IL-31 receptor mediates T helper cell–dependent itch: Involvement of TRPV1 and TRPA1
by Cevikbas, Ferda, PhD and Wang, Xidao, PhD and Akiyama, Tasuku, PhD and Kempkes, Cordula, PhD and Savinko, Terhi, PhD and Antal, Attila, MD and Kukova, Gabriela, MD and Buhl, Timo, MD and Ikoma, Akihiko, MD, PhD and Buddenkotte, Joerg, PhD and Soumelis, Vassili, MD and Feld, Micha, PhD and Alenius, Harri, PhD and Dillon, Stacey R., PhD and Carstens, Earl, PhD and Homey, Bernhard, MD and Basbaum, Allan, PhD and Steinhoff, Martin, MD, PhD
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2013, Volume 133, Issue 2, pp. 448 - 460.e7
Background Although the cytokine IL-31 has been implicated in inflammatory and lymphoma-associated itch, the cellular basis for its pruritic action is yet... 
Allergy and Immunology | sensory nerve | skin | atopic dermatitis | transient receptor potential channel | Cytokine | ATOPIC SKIN INFLAMMATION | DERMATITIS | CHRONIC PRURITUS | IMMUNOLOGY | INTERLEUKIN-31 | NC/NGA MICE | SCRATCHING BEHAVIOR | MURINE MODEL | PAIN | BEHAVIORAL-RESPONSES | ALLERGY | SPINAL NERVE LIGATION | Nerve Tissue Proteins - immunology | Receptors, Interleukin - immunology | TRPV Cation Channels - immunology | Humans | Mice, Inbred C57BL | Sensory Receptor Cells - immunology | Transient Receptor Potential Channels - immunology | Cells, Cultured | Ganglia, Spinal - cytology | Th2 Cells - immunology | Receptors, Interleukin - genetics | TRPV Cation Channels - genetics | Mice, Knockout | Animals | Interleukins - immunology | TRPA1 Cation Channel | Calcium Channels - immunology | Female | Mice | Pruritus - immunology | Skin - immunology | Physiological aspects | Neurosciences | Lymphomas | Neurons | Human subjects | Cell culture | Spinal cord | Psoriasis | Rodents | Mineral oils | Skin diseases | Index Medicus | Abridged Index Medicus
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2. Full Text TSLP: From allergy to vaccine adjuvant
: Highlights
by Soumelis, Vassili
European Journal of Immunology, ISSN 0014-2980, 02/2012, Volume 42, Issue 2, pp. 293 - 295
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3. Full Text Human Inflammatory Dendritic Cells Induce Th17 Cell Differentiation
by Segura, Elodie and Touzot, Maxime and Bohineust, Armelle and Cappuccio, Antonio and Chiocchia, Gilles and Hosmalin, Anne and Dalod, Marc and Soumelis, Vassili and Amigorena, Sebastian
Immunity, ISSN 1074-7613, 02/2013, Volume 38, Issue 2, pp. 336 - 348
Dendritic cells (DCs) are critical regulators of immune responses. Under noninflammatory conditions, several human DC subsets have been identified. Little is... 
IMMUNITY | GROWTH-FACTOR-BETA | 6-SULFO LACNAC | T(H)17 CELLS | GM-CSF | SUBSETS | STEADY-STATE | IMMUNOLOGY | EXPRESSION | INTERLEUKIN-12/23 MONOCLONAL-ANTIBODY | LANGERHANS CELLS | CD4 Antigens - immunology | Inflammation - pathology | Macrophages - pathology | Signal Transduction | Lymphocyte Activation | Dendritic Cells - immunology | Humans | Th1-Th2 Balance | Cells, Cultured | Interleukin-17 - immunology | Dendritic Cells - pathology | Inflammation - immunology | Monocytes - immunology | Transcriptome - immunology | Interleukin-17 - biosynthesis | Organ Specificity | Monocytes - pathology | Inflammation - genetics | Th17 Cells - immunology | Immunologic Memory | Cell Differentiation | Macrophages - immunology | CD4 Antigens - genetics | Th17 Cells - pathology | Dendritic cells | T cells | Analysis | Population | Ligands | Principal components analysis | Morphology | Fluid | Cancer | Index Medicus
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4. Full Text TSLP: From allergy to vaccine adjuvant
by Soumelis, Vassili
European Journal of Immunology, ISSN 0014-2980, 02/2012, Volume 42, Issue 2, pp. 293 - 295
The field of vaccine adjuvants has been an area of active research and development because of the need to improve the generation of protective immunity to a... 
Adjuvant | Vaccine | Cytokine | IMMUNITY | EPITHELIAL-CELLS | DENDRITIC CELLS | GM-CSF | IMMUNOLOGY | T-CELLS | HIV Infections - immunology | HIV-1 - immunology | Animals | env Gene Products, Human Immunodeficiency Virus - immunology | Humans | AIDS Vaccines | Cytokines - administration & dosage | Developing countries | Allergy | Vaccines | Immunoglobulin A | Allergic reaction | Medical research | Immune system | Index Medicus
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5. Full Text Of Human DC Migrants and Residents
by Segura, Elodie and Soumelis, Vassili
Immunity, ISSN 1074-7613, 03/2017, Volume 46, Issue 3, pp. 342 - 344
Migration from peripheral tissues to lymph nodes is a key feature of dendritic cells (DCs), but little is known about the migration patterns of human DCs. By... 
MIGRATION | CCR7 | IMMUNOLOGY | DENDRITIC CELLS | Dendritic Cells | Lymph Nodes | Humans | Cell Movement | Dendritic cells | Analysis | Studies | Pathogens | Genotype & phenotype | Lymphatic system | Migrants | Migration | Organs | Biology | Gene expression | Tissues | Lymph nodes | Index Medicus
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6. Full Text TLR1/2 orchestrate human plasmacytoid predendritic cell response to gram+ bacteria
by Raieli, Salvatore and Trichot, Coline and Korniotis, Sarantis and Pattarini, Lucia and Soumelis, Vassili
PLoS biology, ISSN 1545-7885, 04/2019, Volume 17, Issue 4, pp. e3000209 - e3000209
Gram+ infections are worldwide life-threatening diseases in which the pathological role of type I interferon (IFN) has been highlighted. Plasmacytoid... 
Differentiation (biology) | Infections | Lymphocytes T | Kinases | Dermatitis | Proteins | Pathways | Granulocytes | Lymphocytes | Toll-like receptors | Bacteria | Tumor necrosis factor-TNF | NF-κB protein | Lymphatic system | Cytokines | Dendritic cells | Secretion | MAP kinase | Priming | Inflammation | Cell differentiation | Investigations | 1-Phosphatidylinositol 3-kinase | Costimulator | CD4 antigen | Lipoproteins | TLR1 protein | Tuberculosis | Influenza | TLR2 protein | Ligands | Interferon | Human behavior | Cancer | Apoptosis | Life Sciences | Human health and pathology | Immunology | Infectious diseases
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7. Full Text Keeping skin inflammation local
by Pattarini, Lucia and Soumelis, Vassili
Nature Immunology, ISSN 1529-2908, 02/2017, Volume 18, Issue 3, pp. 250 - 251
Silencing of the chromatin remodeler Mi-2 beta in keratinocytes triggers local skin inflammation. Regulatory T cells activated by the cytokine TSLP control the... 
REGULATORY T-CELLS | IMMUNITY | IMMUNOLOGY | DENDRITIC CELLS | TSLP | INDUCE | Inflammation | Skin | Dermatitis | Humans | Physiological aspects | Keratinocytes | T cells | Health aspects | Immunological research | Index Medicus
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8. Full Text A critical function for transforming growth factor-β, interleukin 23 and proinflammatory cytokines in driving and modulating human TH-17 responses
by Volpe, Elisabetta and Servant, Nicolas and Zollinger, Raphaël and Bogiatzi, Sofia I and Hupé, Philippe and Barillot, Emmanuel and Soumelis, Vassili
Nature Immunology, ISSN 1529-2908, 06/2008, Volume 9, Issue 6, pp. 650 - 657
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9. Full Text NRP-1 and IL-17-producing NKT cells
by Soumelis, Vassili
Blood, ISSN 0006-4971, 09/2011, Volume 118, Issue 11, pp. 2934 - 2935
DENDRITIC CELLS | RECEPTORS | HEMATOLOGY | NEUROPILINS | T-CELLS | SEMAPHORINS | Chemotaxis, Leukocyte | Interleukin-17 - metabolism | Animals | Natural Killer T-Cells - metabolism | Neuropilin-1 - metabolism | Lymphoid Tissue - immunology | Natural Killer T-Cells - physiology | Index Medicus | Abridged Index Medicus
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10. Full Text TLR recognition of self nucleic acids hampers glucocorticoid activity in lupus
by Barrat, Franck J and Soumelis, Vassili and Chaussabel, Damien and Punaro, Marilynn and Guiducci, Cristiana and Wright, Tracey and Coffman, Robert L and Gill, Michelle and Meeker, Thea and Bolland, Silvia and Banchereau, Jacques and Xu, Zhaohui and Gong, Mei and Pascual, Virginia and Chan, Jean H
Nature, ISSN 0028-0836, 06/2010, Volume 465, Issue 7300, pp. 937 - 941
Glucocorticoids are widely used to treat patients with autoimmune diseases such as systemic lupus erythematosus (SLE). However, regimens used to treat many... 
PLASMACYTOID DENDRITIC CELLS | SYSTEMIC-LUPUS | GENE | AUTOIMMUNE-DISEASES | MULTIDISCIPLINARY SCIENCES | RECEPTOR | MICE | CORTICOSTEROIDS | ERYTHEMATOSUS | I INTERFERON | BLOOD | Cell Survival - drug effects | Up-Regulation | Humans | Mice, Inbred C57BL | Cells, Cultured | NF-kappa B - immunology | Male | Interferons - immunology | Interferon-alpha - immunology | Toll-Like Receptor 9 - immunology | Autoantibodies - immunology | Animals | Toll-Like Receptor 7 - immunology | Adolescent | Glucocorticoids - pharmacology | Dendritic Cells - drug effects | Female | Mice | Nucleic Acids - immunology | Membrane Glycoproteins - immunology | Lupus Erythematosus, Systemic - physiopathology | Child | Disease Models, Animal | Cell receptors | Transcription factors | Systemic lupus erythematosus | Physiological aspects | Genetic aspects | Research | Drug therapy | Health aspects | Immunosuppressive agents | Proteins | Spleen | Flow cytometry | Disease | Review boards | Kinases | Autoimmune diseases | Apoptosis | Immune system | Index Medicus
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11. Full Text Skin thymic stromal lymphopoietin initiates Th2 responses through an orchestrated immune cascade
by Leyva-Castillo, Juan Manuel and Hener, Pierre and Michea, Paula and Karasuyama, Hajime and Chan, Susan and Soumelis, Vassili and Li, Mei
Nature Communications, ISSN 2041-1723, 11/2013, Volume 4, Issue 1, pp. 2847 - 2847
Thymic stromal lymphopoietin (TSLP) has emerged as a key initiator in Th2 immune responses, but the TSLP-driven immune cascade leading to Th2 initiation... 
ALLERGIC INFLAMMATION | ATOPIC-DERMATITIS | HELMINTH INFECTION | DENDRITIC CELLS | MOUSE KERATINOCYTES | MULTIDISCIPLINARY SCIENCES | IN-VIVO | CD4(+) T-CELLS | HELPER TYPE-2 RESPONSE | IL-4 PRODUCTION | LANGERHANS CELLS | Skin - cytology | Dendritic Cells - immunology | Male | Th2 Cells - immunology | Mice, Knockout | CD4-Positive T-Lymphocytes - immunology | Interleukin-4 - immunology | Animals | Basophils - immunology | Female | Mice | Mice, Inbred BALB C | Cytokines - genetics | Cytokines - immunology | Skin - immunology | Index Medicus
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12. Full Text Thymic stromal lymphopoietin links keratinocytes and dendritic cell–derived IL-23 in patients with psoriasis
by Volpe, Elisabetta, PhD and Pattarini, Lucia, PhD and Martinez-Cingolani, Carolina, PhD and Meller, Stephan, MD and Donnadieu, Marie-Helene, MSc and Bogiatzi, Sofia I., MD, PhD and Fernandez, Maria I., PhD and Touzot, Maxime, MD, PhD and Bichet, Jean-Christophe, MD and Reyal, Fabien, MD, PhD and Paronetto, Maria Paola, PhD and Chiricozzi, Andrea, MD and Chimenti, Sergio, MD and Nasorri, Francesca, PhD and Cavani, Andrea, MD, PhD and Kislat, Andreas, MSc and Homey, Bernhard, MD, PhD and Soumelis, Vassili, MD, PhD
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2014, Volume 134, Issue 2, pp. 373 - 381.e4
Background Thymic stromal lymphopoietin (TSLP) is a major proallergic cytokine that promotes TH 2 responses through dendritic cell (DC) activation. Whether it... 
Allergy and Immunology | Thymic stromal lymphopoietin | dendritic cells | IL-23 | psoriasis | CD40 ligand | skin inflammation | HUMAN EPITHELIAL-CELLS | CYTOKINE | IMMUNOLOGY | CUTTING EDGE | ATOPIC-DERMATITIS | GROWTH-FACTOR-BETA | IL-12 PRODUCTION | ALLERGY | INFLAMMATION | TSLP EXPRESSION | T-CELLS | Dermatitis, Atopic - genetics | Dendritic Cells - immunology | Humans | Middle Aged | Dendritic Cells - pathology | Male | STAT6 Transcription Factor - genetics | Th2 Cells - immunology | CD40 Ligand - immunology | Interleukin-23 - genetics | Psoriasis - genetics | Psoriasis - pathology | Dermatitis, Atopic - immunology | Adult | Interleukin-4 - genetics | Cytokines - genetics | Skin - pathology | Th2 Cells - pathology | Cytokines - immunology | Skin - immunology | Psoriasis - immunology | Signal Transduction | Gene Expression Regulation | Dermatitis, Atopic - pathology | STAT6 Transcription Factor - immunology | Interleukin-23 - immunology | Keratinocytes - immunology | Interleukin-4 - immunology | Keratinocytes - pathology | CD40 Ligand - genetics | Primary Cell Culture | Care and treatment | Inflammation | Psoriasis | Dendritic cells | Neurophysiology | Biopsy | Lymphocytes | Colleges & universities | Blood banks | Experiments | Immune system | Index Medicus | Abridged Index Medicus
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13. Full Text The DNA repair inhibitor Dbait is specific for malignant hematologic cells in blood
by Thierry, Sylvain and Jdey, Wael and Alculumbre, Solana and Soumelis, Vassili and Noguiez-Hellin, Patricia and Dutreix, Marie
Molecular Cancer Therapeutics, ISSN 1535-7163, 12/2017, Volume 16, Issue 12, pp. 2817 - 2827
Hematologic malignancies are rare cancers that develop refractory disease upon patient relapse, resulting in decreased life expectancy and quality of life. DNA... 
DT01 | ONCOLOGY | GENES | RADIOTHERAPY | PARP INHIBITORS | COMBINATION | CANCER | EXPRESSION | CHEMOTHERAPY | Cell proliferation | Lipoproteins (low density) | Biotechnology | Salts | Toxicity | Leukemia | p53 Protein | DNA damage | Molting | Lymphocytes T | Kinases | DNA repair | Blood | Receptors | Platinum | Lymphocytes | Bone marrow | Repair | Deoxyribonucleic acid--DNA | CD34 antigen | Life expectancy | Blood cells | Etoposide | Radiation therapy | Tumor cell lines | Lymphoma | Cholesterol | Quality of life | Signaling | Bone cancer | DNA-dependent protein kinase | Life span | Protein kinase | Cell death | Cell lines | Stem cells | Combined treatment | Tumors | Cancer | Index Medicus
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14. Full Text TSLP-activated dendritic cells induce human T follicular helper cell differentiation through OX40-ligand
by Pattarini, Lucia and Trichot, Coline and Bogiatzi, Sofia and Grandclaudon, Maximilien and Meller, Stephan and Keuylian, Zela and Durand, Melanie and Volpe, Elisabetta and Madonna, Stefania and Cavani, Andrea and Chiricozzi, Andrea and Romanelli, Marco and Hori, Toshiyuki and Hovnanian, Alain and Homey, Bernhard and Soumelis, Vassili
Journal of Experimental Medicine, ISSN 0022-1007, 05/2017, Volume 214, Issue 5, pp. 1529 - 1546
T follicular helper cells (Tfh) are important regulators of humoral responses. Human Tfh polarization pathways have been thus far associated with Th1 and Th17... 
B-CELLS | MEDICINE, RESEARCH & EXPERIMENTAL | ATOPIC-DERMATITIS | TH2 RESPONSES | NETHERTON SYNDROME | TFH CELLS | OX40 LIGAND | ALLERGIC DISEASE | IMMUNOLOGY | FH CELLS | EXPRESSION | THYMIC STROMAL LYMPHOPOIETIN | Receptors, CXCR5 - metabolism | Th2 Cells - physiology | Humans | Dendritic Cells - physiology | Programmed Cell Death 1 Receptor - metabolism | Cytokines - physiology | Interleukins - metabolism | Chemokine CXCL13 - metabolism | Proto-Oncogene Proteins c-bcl-6 - metabolism | Inducible T-Cell Co-Stimulator Protein - metabolism | OX40 Ligand - physiology | Cell Differentiation - physiology | Receptors, Immunologic - metabolism | Polarization | Regulators | Helper cells | CXCL13 protein | Differentiation (biology) | Immunoglobulin E | Lymphocytes T | Dermatitis | SAP protein | Thymus | Pathways | CXCR5 protein | Lymphocytes | BTLA protein | Atopic dermatitis | Interleukin 21 | Immunological memory | Memory cells | Dendritic cells | Secretion | Inflammation | Cell differentiation | CD4 antigen | Ox40L protein | Thymic stromal lymphopoietin | Lymphocytes B | Tumor necrosis factor | ICOS protein | Ligands | Human behavior | Bcl-6 protein | Index Medicus | 311
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15. Full Text A critical function for transforming growth factor-β, interleukin 23 and proinflammatory cytokines in driving and modulating human T H -17 responses
by Zollinger, Raphaël and Bogiatzi, Sofia I and Soumelis, Vassili and Hupé, Philippe and Volpe, Elisabetta and Servant, Nicolas and Barillot, Emmanuel
Nature Immunology, ISSN 1529-2908, 06/2008, Volume 9, Issue 6, pp. 650 - 657
Interleukin 17 (IL-17)-producing T helper 17 cells (T-H-17 cells) have been described as a T helper cell subset distinct from T helper type 1 (T(H)1) and T(H)2... 
T(H)17 CELLS | TGF-BETA | DENDRITIC CELLS | INFLAMMATION | IL-17 | DIFFERENTIATION | IMMUNOLOGY | IL-23 | AUTOIMMUNE ENCEPHALOMYELITIS | T-HELPER-CELLS | TH17 CELLS
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