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JOURNAL OF BIOLOGICAL CHEMISTRY, ISSN 0021-9258, 04/2019, Volume 294, Issue 15, pp. 5805 - 5806
T-cell receptors (TCRs) recognize pathogens to ignite immune responses, making them attractive scaffolds for development as immunotherapeutics. However,... 
CYTOMEGALOVIRUS | SELECTION | BIOCHEMISTRY & MOLECULAR BIOLOGY | Editors' Picks Highlights
Journal Article
Immunity, ISSN 1074-7613, 05/2015, Volume 42, Issue 5, pp. 815 - 825
Journal Article
Current Opinion in Chemical Engineering, ISSN 2211-3398, 03/2018, Volume 19, pp. 27 - 34
Fundamental advances in the field of biomolecular engineering present researchers with the unprecedented opportunity to apply molecular design strategies to... 
HALF-LIFE | ENGINEERING, CHEMICAL | INTERLEUKIN-6 RECEPTOR | DISPLAY | FUSION | PHARMACOKINETICS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | NECROSIS-FACTOR-ALPHA | IL-2 | MONOCLONAL-ANTIBODY THERAPY | CANCER | CYTOTOXICITY
Journal Article
Nature, ISSN 0028-0836, 01/2019, Volume 565, Issue 7738, pp. 186 - 191
We describe a de novo computational approach for designing proteins that recapitulate the binding sites of natural cytokines, but are otherwise unrelated in... 
HALF-LIFE | INTERLEUKIN-2 | MOLECULAR-DYNAMICS | NEUTRALIZING ANTIBODIES | MULTIDISCIPLINARY SCIENCES | RECEPTOR | ALPHA | CYTOKINE | GENERATION | T-CELL | PROTEINS | Colonic Neoplasms - drug therapy | Humans | Interleukin-2 - therapeutic use | Crystallography, X-Ray | Interleukin-15 - immunology | Signal Transduction - immunology | Molecular Mimicry | Interleukin-2 - immunology | Colonic Neoplasms - immunology | Computer Simulation | Drug Design | Interleukin-15 - therapeutic use | Protein Stability | Binding Sites | Disease Models, Animal | Interleukin-2 Receptor alpha Subunit - immunology | Amino Acid Sequence | Models, Molecular | Receptors, Interleukin-2 - metabolism | Receptors, Interleukin-2 - immunology | Animals | Interleukin-2 Receptor alpha Subunit - metabolism | Melanoma - immunology | Melanoma - drug therapy | Mice | Receptors, Interleukin-2 - agonists | Physiological aspects | Protein engineering | Interleukin-15 | Interleukin-2 | Methods | Interleukin 2 receptors | Animal models | Cytokines | Toxicity | Interleukin | Melanoma | Amino acid sequence | Topology | Interleukin 15 | Design optimization | Design | Proteins | Signaling | Colon cancer | Interleukin 2 | Immunogenicity | Computer applications | CD25 antigen | Software | Colon | Binding sites | Cancer | Crystal structure | Index Medicus | cytokine | functional | interleukin-2 | Neo-2 | hyper-stable | De novo | interleukin-15 | therapeutic | Neoleukin-2 | protein | design | il-15 | il-2 | mimetic | Neoleukin | mimic | cancer
Journal Article
by Gerstein, Hertzel C and Miller, Michael E and Byington, Robert P and Goff, David C and Bigger, J. Thomas and Buse, John B and Cushman, William C and Genuth, Saul and Ismail-Beigi, Faramarz and Grimm, Richard H and Probstfield, Jeffrey L and Simons-Morton, Denise G and Friedewald, William T and Gotto, A.M and Bailey, K and Gohdes, D and Haffner, S and Hiss, R and Jamerson, K and Lee, K and Nathan, D and Sowers, J and Walters, L and Friedewald, W.T and Buse, J.B and Bigger, J.T and Byington, Robert P and Cushman, W.C and Gerstein, H.C and Ginsberg, H.N and Goff, David C and Probstfield, J.L and Simons-Morton, D.G and Gerstein, H.C and Yusuf, S and Punthakee, Z and Russo, R and Anand, S and Cracknell, B and Cukierman-Yaffe, T and Gafni, A and Guyatt, G and Hall, S and Kaszyca, J and Lonn, E and McLeod, D and Read, K and Reiding, V and Shehadeh, N and Tadeson, B and Thompson, K and Vallis, M and Vasudeva, V and Wilderman, I and Punthakee, Z and Smith, A and Stanton, I and Capes, S and Danby, S and Harper, W and Harvey, P and Hunt, D and Manjoo, P and Moroso, A and Otto, R and Prebtani, A and Valla, T and Davis, A and Capes, S and Hill, K.L and McCarthy, V and Edwards, A.L and Mitchell, D.J and Clearwaters, M.A and Dielissen, C and Gillam, M and Hammond, B and Jensen, H and Kherani, A and Lau, D and Pringle, V and Rabi, D and Sigal, R and Smith, C and Walker, M and Williams, G and Joyce, C and Parsons, M and Rowe, B and Burton, J and Chandurkar, V and Coady-McDonald, S and Gibbons, D and Kovacs, C and Murphy, B and Smart, R and Varghese, S and Mereu, L and Ryan, E and Senior, P and ... and The Action to Control Cardiovascular Risk in Diabetes Study Group and Act Control Cardiovasc Risk Diabet and Action to Control Cardiovascular Risk in Diabetes Study Group
The New England Journal of Medicine, ISSN 0028-4793, 06/2008, Volume 358, Issue 24, pp. 2545 - 2559
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2010, Volume 107, Issue 30, pp. 13252 - 13257
Journal Article
Electrochimica Acta, ISSN 0013-4686, 11/2014, Volume 145, pp. 291 - 299
Extremely thin absorber (ETA) solar cells can theoretically provide higher efficiencies than planar cells for low quality absorbers, but only if their... 
Buffer layer | Bulk recombination | ETA solar cell | Photovoltaic | CdS | Interfacial recombination | ELECTROCHEMISTRY | DESIGN | SEMICONDUCTORS | PERFORMANCE | BEHAVIOR | SULFIDE | PHOTOVOLTAIC CELLS | COATINGS | CHEMICAL BATH DEPOSITION | LAYER | EFFICIENCY | Solar cells | Solar batteries | Zinc oxide | Photovoltaic cells | Morphology | Cadmium sulfides | Intermetallics | Nanostructure | Nanowires | Cadmium selenides
Journal Article
Immunity, ISSN 1074-7613, 05/2015, Volume 42, Issue 5, pp. 826 - 838
Journal Article