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1. Full Text Secondary prevention trials in preclinical Alzheimer's disease
by Sperling, Reisa
Neurobiology of Aging, ISSN 0197-4580, 2016, Volume 39, pp. S16 - S16
Neurology | Internal Medicine | Prevention | Clinical trials | Drug therapy | Alzheimer's disease
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2. Full Text Dr. Salloway and colleagues reply
by Salloway, Stephen and Sperling, Reisa and Brashear, H. Robert
New England Journal of Medicine, ISSN 0028-4793, 2014, Volume 370, Issue 15, p. 1460
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3. Full Text Preliminary Results of a Trial of Atabecestat in Preclinical Alzheimer’s Disease
by Romano, Gary and Henley, David and Aisen, Paul and Sperling, Reisa and Raghavan, Nandini and Raman, Rema
The New England Journal of Medicine, ISSN 0028-4793, 04/2019, Volume 380, Issue 15, pp. 1483 - 1485
A preliminary analysis of a trial involving participants with brain amyloid deposition who are at risk for dementia due to Alzheimer’s disease showed no... 
Dementia disorders | Secretase | Cognitive ability
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4. Full Text What Happens with the Circuit in Alzheimer’s Disease in Mice and Humans?
by Zott, Benedikt and Busche, Marc Aurel and Sperling, Reisa A and Konnerth, Arthur
Annual review of neuroscience, ISSN 0147-006X, 7/2018, Volume 41, pp. 277 - 297
A major mystery of many types of neurological and psychiatric disorders, such as Alzheimer’s disease (AD), remains the underlying, disease-specific neuronal... 
slow-wave oscillations | hippocampus | hyperactivity | memory consolidation | default mode network | imaging
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5. Full Text 0300 Linking Sleep Disturbances with Amyloid and Tau Imaging. Preliminary Findings from the Harvard Aging Brain Study
by Djonlagic, Ina and Chhatwal, Jasmeer and Schulz, Aaron and Hampton, Olivia and Kirn, Dylan and Papp, Kathryn and Rentz, Dorene and Johnson, Keith and Sperling, Reisa and Redline, Susan
Sleep, ISSN 0161-8105, 04/2019, Volume 42, Issue Supplement_1, pp. A122 - A123
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6. Full Text Clinical Evaluation of Amyloid-Related Imaging Abnormalities in Bapineuzumab Phase III Studies
by Brashear, H. Robert and Ketter, Nzeera and Bogert, Jennifer and Di, Jianing and Salloway, Stephen P and Sperling, Reisa
Journal of Alzheimer's Disease, ISSN 1387-2877, 2018, Volume 66, Issue 4, pp. 1409 - 1424
Background: Amyloid-related imaging abnormalities with effusion or edema (ARIA-E) reported in patients with mild-to-moderate Alzheimer's disease in... 
clinical evaluation | bapineuzumab | Amyloid-related imaging abnormality | TRIALS | ALZHEIMERS-DISEASE | EDEMA | ANGIOPATHY | NEUROSCIENCES | Edema | Medical imaging | Effusion | Abnormalities | Cognitive ability | Cognition | Risk analysis | Patients | Risk factors | Carriers | Magnetic resonance imaging | Cognition & reasoning | Magnetic permeability | Apolipoprotein E | Index Medicus
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7. Full Text Amyloid Imaging of Dutch‐type Hereditary Cerebral Amyloid Angiopathy Carriers
by Schultz, Aaron and Kloet, Reina W and Sohrabi, Hamid R and Weerd, Louise and Rooden, Sanneke and Wermer, Marieke J.H and Grand Moursel, Laure and Yaqub, Maqsood and Berckel, Bart N.M and Chatterjee, Pratishtha and Gardener, Samantha L and Taddei, Kevin and Fagan, Anne M and Benzinger, Tammie L and Morris, John C and Sperling, Reisa and Johnson, Keith and Bateman, Randall J and Gurol, M. Edip and Buchem, Mark A and Martins, Ralph and Chhatwal, Jasmeer and Greenberg, Steven M and Dominantly Inherited Alzheimer Network
Annals of Neurology, ISSN 0364-5134, 07/2019
OBJECTIVETo determine whether amyloid imaging with the positron emission tomography (PET) agent Pittsburgh compound B (PiB) can detect vascular β-amyloid (Aβ)... 
Index Medicus
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8. Full Text Discussant
by Sperling, Reisa A
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 2013, Volume 9, Issue 4, pp. P826 - P826
Neurology
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9. Full Text Correction: Quantitative Amyloid Imaging in Autosomal Dominant Alzheimer’s Disease: Results from the DIAN Study Group
by Su, Yi and Blazey, Tyler M and Owen, Christopher J and Christensen, Jon J and Friedrichsen, Karl and Joseph-Mathurin, Nelly and Wang, Qing and Hornbeck, Russ C and Ances, Beau M and Snyder, Abraham Z and Cash, Lisa A and Koeppe, Robert A and Klunk, William E and Galasko, Douglas and Brickman, Adam M and McDade, Eric and Ringman, John M and Thompson, Paul M and Saykin, Andrew J and Ghetti, Bernardino and Sperling, Reisa A and Johnson, Keith A and Salloway, Stephen P and Schofield, Peter R and Masters, Colin L and Villemagne, Victor L and Fox, Nick C and Förster, Stefan and Chen, Kewei and Reiman, Eric M and Xiong, Chengjie and Marcus, Daniel S and Weiner, Michael W and Morris, John C and Bateman, Randall J and Benzinger, Tammie L. S and Dominantly Inherited Alzheimer Network
PLOS ONE, ISSN 1932-6203, 09/2016, Volume 11, Issue 9, p. e0163669
Amyloid
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10. Full Text Seizures as an early symptom of autosomal dominant Alzheimer's disease
by Vöglein, Jonathan and Noachtar, Soheyl and McDade, Eric and Quaid, Kimberly A and Salloway, Stephen and Ghetti, Bernardino and Noble, James and Berman, Sarah and Chhatwal, Jasmeer and Mori, Hiroshi and Fox, Nick and Allegri, Ricardo and Masters, Colin L and Buckles, Virginia and Ringman, John M and Rossor, Martin and Schofield, Peter R and Sperling, Reisa and Jucker, Mathias and Laske, Christoph and Paumier, Katrina and Morris, John C and Bateman, Randall J and Levin, Johannes and Danek, Adrian and Dominantly Inherited Alzheimer Net and Dominantly Inherited Alzheimer Network
Neurobiology of Aging, ISSN 0197-4580, 04/2019, Volume 76, pp. 18 - 23
Our objective was to assess the reported history of seizures in cognitively asymptomatic mutation carriers for autosomal dominant Alzheimer's disease (ADAD)... 
Autosomal dominant | Genetics | Positive predictive value | Alzheimer's disease | Seizures | Dementia | MUTATION | RISK | EPILEPSY | NEUROSCIENCES | ONSET | GERIATRICS & GERONTOLOGY | Seizures (Medicine)
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11. Full Text Biomarker pattern of ARIA-E participants in phase 3 randomized clinical trials with bapineuzumab
by Liu, Enchi and Wang, Dai and Sperling, Reisa and Salloway, Stephen and Fox, Nick C and Blennow, Kaj and Scheltens, Philip and Schmidt, Mark E and Streffer, Johannes and Novak, Gerald and Einstein, Steve and Booth, Kevin and Ketter, Nzeera and Brashear, H Robert and ELN115727-301 302 Investigator Grp and ELN115727-301/302 Investigator Group and For the ELN115727-301/302 Investigator Group and Sahlgrenska akademin and Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi and Göteborgs universitet and Gothenburg University and Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry and Sahlgrenska Academy
Neurology, ISSN 0028-3878, 03/2018, Volume 90, Issue 10, pp. e877 - e886
OBJECTIVETo evaluate whether amyloid-related imaging abnormalities with edema/effusion (ARIA-E) observed in bapineuzumab clinical trials was associated with... 
MODERATE ALZHEIMERS-DISEASE | CEREBROSPINAL-FLUID BIOMARKERS | IMAGING ABNORMALITIES | AMYLOID-BETA | CLINICAL NEUROLOGY | Neurosciences | Neurovetenskaper
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12. Full Text Decreased body mass index in the preclinical stage of autosomal dominant Alzheimer's disease
by Müller, Stephan and Preische, Oliver and Sohrabi, Hamid R and Gräber, Susanne and Jucker, Mathias and Dietzsch, Janko and Ringman, John M and Martins, Ralph N and McDade, Eric and Schofield, Peter R and Ghetti, Bernardino and Rossor, Martin and Graff-Radford, Neill R and Levin, Johannes and Galasko, Douglas and Quaid, Kimberly A and Salloway, Stephen and Xiong, Chengjie and Benzinger, Tammie and Buckles, Virginia and Masters, Colin L and Sperling, Reisa and Bateman, Randall J and Morris, John C and Laske, Christoph
Scientific Reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, pp. 1225 - 1225
The relationship between body-mass index (BMI) and Alzheimer's disease (AD) has been extensively investigated. However, BMI alterations in preclinical... 
OLDER PERSONS | COGNITIVE DECLINE | OBESITY | DEMENTIA | METABOLISM | GLUCOSE | MULTIDISCIPLINARY SCIENCES | WEIGHT-LOSS | RISK | PATHOLOGY | ANOREXIA | Index Medicus
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13. Full Text Amyloid-Related Imaging Abnormalities (ARIA)
by Sperling, Reisa
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 2012, Volume 8, Issue 4, pp. P606 - P606
Neurology
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14. Full Text Long-Term Follow Up of Patients with Mild-to-Moderate Alzheimer’s Disease Treated with Bapineuzumab in a Phase III, Open-Label, Extension Study
by Salloway, Stephen P and Sperling, Reisa and Fox, Nick C and Sabbagh, Marwan N and Honig, Lawrence S and Porsteinsson, Anton P and Rofael, Hany and Ketter, Nzeera and Wang, Daniel and Liu, Enchi and Carr, Stephen and Black, Ronald S and Brashear, H. Robert
Journal of Alzheimer's Disease, ISSN 1387-2877, 07/2018, Volume 64, Issue 3, pp. 689 - 707
Background: A 3-year extension of two Phase III parent studies of intravenous (IV) bapineuzumab in patients with mild-to-moderate Alzheimer’s disease dementia... 
Carriers | Studies | Infusion | Intravenous administration | Apolipoprotein E | Dementia disorders | Cognition | Urinary tract | Safety | Apolipoproteins | Patients | Two phase
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15. Full Text Tau accumulation observed using repeated PET measures is associated with cognitive decline in normal elderly
by Hanseeuw, Bernard and Reisa, Sperling and Johnson, Keith
Revue Neurologique, ISSN 0035-3787, 04/2018, Volume 174, pp. S176 - S176
Tau | Cognition | Amyloid
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16. Full Text SAMPLE SIZES FOR 24-MONTH ALZHEIMER’S PREVENTION TRIALS USING BIOMARKER ENDPOINTS IN COGNITIVELY UNIMPAIRED AMYLOID-POSITIVE ADULTS
by Reiman, Eric M and Kuang, Xiaoying and Luo, Ji and Chen, Yinghua and Thiyyagura, Pradeep and Bauer, Robert and Lee, Wendy and Protas, Hillary and Goradia, Dhruman D and Aisen, Paul S and Johnson, Keith and Langbaum, Jessica B and Sperling, Reisa A and Tariot, Pierre and Jagust, William J and Weiner, Michael and Chen, Kewei
Alzheimer's & Dementia, ISSN 1552-5260, 07/2017, Volume 13, Issue 7, pp. P36 - P37
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17. Full Text SAMPLE SIZES FOR 24-MONTH ALZHEIMER’S PREVENTION TRIALS USING BIOMARKER ENDPOINTS IN COGNITIVELY UNIMPAIRED AMYLOID-POSITIVE ADULTS
by Reiman, Eric M and Kuang, Xiaoying and Luo, Ji and Chen, Yinghua and Thiyyagura, Pradeep and Bauer, Robert and Lee, Wendy and Protas, Hillary and Goradia, Dhruman D and Aisen, Paul S and Johnson, Keith and Langbaum, Jessica B and Sperling, Reisa A and Tariot, Pierre and Jagust, William J and Weiner, Michael and Chen, Kewei
Alzheimer's & Dementia, ISSN 1552-5260, 07/2017, Volume 13, Issue 7, pp. P1453 - P1454
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18. Full Text Steps to standardization and validation of hippocampal volumetry as a biomarker in clinical trials and diagnostic criterion for Alzheimer's disease
by Jack, C.R and Barkhof, F and Bernstein, M.A and Cantillon, M and Cole, P.E and deCarli, C and Dubois, B and Duchesne, S and Fox, N.C and Frisoni, G. B and Hampel, H and Hill, D.L.G and Johnson, K and Mangin, J.F and Scheltens, P and Schwarz, A.J and Sperling, R and Suhy, J and Thompson, P.M and Weiner, M and Foster, N.L
Dementia, ISSN 1552-5260, 2011, Volume 7, Issue 4, pp. 474 - e4
Background: The promise of Alzheimer's disease biomarkers has led to their incorporation in new diagnostic criteria and in therapeutic trials; however,... 
Biomarkers | Biomarker standards | Magnetic resonance imaging | Alzheimer's disease | Hippocampus | BRAIN ATROPHY | DEMENTIA | CLASSIFICATION | MILD COGNITIVE IMPAIRMENT | MRI MEASURES | CLINICAL NEUROLOGY | PREDICTORS | SEGMENTATION | PROBABLE AD | MEDIAL TEMPORAL ATROPHY | PROGRESSION | Reproducibility of Results | Europe | Humans | Biomarkers - analysis | Magnetic Resonance Imaging - methods | Male | Reference Values | Hippocampus - pathology | Alzheimer Disease - diagnosis | Image Processing, Computer-Assisted | Magnetic Resonance Imaging - standards | Aged, 80 and over | Female | ROC Curve | Aged | Index Medicus
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19. Full Text IN VIVO SPREADING PATHWAYS OF TAU AND AMYLOID ACCUMULATION AND ITS GENETIC UNDERPINNINGS
by Sepulcre, Jorge and Grothe, Michel J and Sperling, Reisa A and Johnson, Keith
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 07/2017, Volume 13, Issue 7, pp. P1246 - P1246
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20. Full Text TRC-PAD: USING RUN-IN DATA FOR SCREEN FAILURE REDUCTION
by Aisen, Paul S and Cummings, Jeffrey L and Sperling, Reisa A
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 2016, Volume 12, Issue 7, pp. P372 - P372
Neurology
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