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1. Full Text The potential of functional MRI as a biomarker in early Alzheimer's disease
by Sperling, Reisa
Neurobiology of aging, ISSN 0197-4580, 2011, Volume 32, Issue 1, pp. S37 - S43
Neurology | Internal Medicine | Functional magnetic resonance imaging | fMRI | Biomarker | Alzheimer's disease | Cognitive impairment | Dementia | FMRI | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Geriatrics & Gerontology | Science & Technology | Alzheimer Disease - diagnosis | Alzheimer Disease - physiopathology | Brain - physiopathology | Humans | Memory | Biomarkers | Brain - pathology | Magnetic Resonance Imaging - methods | Risk | Cognition | Alzheimer Disease - pathology | Magnetic resonance imaging | Index Medicus | dementia | cognitive impairment | Alzheimer’s disease | biomarker | functional magnetic resonance imaging
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2. Full Text The Evolution of Preclinical Alzheimer’s Disease: Implications for Prevention Trials
by Sperling, Reisa and Mormino, Elizabeth and Johnson, Keith
Neuron (Cambridge, Mass.), ISSN 0896-6273, 11/2014, Volume 84, Issue 3, pp. 608 - 622
Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Neuroimaging | Drug Evaluation, Preclinical - methods | Alzheimer Disease - complications | Humans | Alzheimer Disease - drug therapy | Cognition Disorders - drug therapy | Alzheimer Disease - diagnosis | Animals | Cognition Disorders - prevention & control | Alzheimer Disease - prevention & control | Antipsychotic Agents - therapeutic use | Cognition Disorders - etiology | Biomedical Research - methods | Prevention | Clinical trials | Alzheimer's disease | Studies | Disease prevention | Hypotheses | Heart attacks | Neurodegeneration | Mortality | Biomarkers | Cardiovascular disease | Mutation | Alzheimers disease | Index Medicus
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3. Full Text What Happens with the Circuit in Alzheimer's Disease in Mice and Humans?
by Zott, Benedikt and Busche, Marc Aurel and Sperling, Reisa A and Konnerth, Arthur
Annual review of neuroscience, ISSN 0147-006X, 7/2018, Volume 41, Issue 1, pp. 277 - 297
slow-wave oscillations | hippocampus | hyperactivity | default mode network | memory consolidation | imaging | Animals | Brain - physiopathology | Humans | Brain - pathology | Mice | Neural Pathways - pathology | Neural Pathways - physiopathology | Nerve Net - pathology | Nerve Net - physiopathology | Alzheimer Disease - pathology | Disease Models, Animal | Physiological aspects | Alzheimer's disease | Neural circuitry | Neuroimaging | Animal models | Neurodegenerative diseases | Mental disorders | Hyperactivity | Excitability | Behavior disorders | Neurological diseases | Rodents | Alzheimers disease | Laboratory animals | Neurological disorders | Index Medicus
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4. Full Text Secondary prevention trials in preclinical Alzheimer's disease
by Sperling, Reisa
Neurobiology of aging, ISSN 0197-4580, 2016, Volume 39, pp. S16 - S16
Neurology | Internal Medicine | Prevention | Clinical trials | Drug therapy | Alzheimer's disease
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5. Full Text Tau accumulation in clinically normal older adults is associated with hippocampal hyperactivity
by Huijbers, Willem and Schultz, Aaron P and Papp, Kathryn V and LaPoint, Molly R and Hanseeuw, Bernard and Chhatwal, Jasmeer P and Hedden, Trey and Johnson, Keith A and Sperling, Reisa A
The Journal of neuroscience, ISSN 0270-6474, 01/2019, Volume 39, Issue 3, pp. 548 - 556
NEURONAL-ACTIVITY | BASE-LINE | AMYLOID DEPOSITION | memory | ALZHEIMERS-DISEASE | PiB | MILD COGNITIVE IMPAIRMENT | BETA DEPOSITION | MOUSE MODELS | fMRI | flortaucipir | EPILEPTIFORM ACTIVITY | AUTOSOMAL-DOMINANT | BRAIN ACTIVATION | excitotoxicity | Alzheimer's disease | Alzheimer’s disease | Flortaucipir | Excitotoxicity | Memory | FMRI | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Psychomotor Performance | Alzheimer Disease - physiopathology | Humans | Middle Aged | tau Proteins - metabolism | Male | Positron-Emission Tomography | Temporal Lobe - diagnostic imaging | Temporal Lobe - metabolism | Hippocampus - diagnostic imaging | Hippocampus - metabolism | Magnetic Resonance Imaging | Amyloid beta-Peptides - metabolism | Aged, 80 and over | Brain Mapping | Female | Aged | Alzheimer Disease - diagnostic imaging | Hippocampus - physiopathology | Neuroimaging | Brain | Nuclear magnetic resonance--NMR | Pathogenesis | Hyperactivity | Males | Accumulation | Proteins | Older people | Tomography | Functional magnetic resonance imaging | Dementia disorders | Aging | Amyloid | Cortex (temporal) | Apolipoprotein E4 | Medical imaging | Neurodegenerative diseases | Cortex | Brain mapping | Positron emission | Emissions | Cortex (entorhinal) | Pathology | Neurology | Magnetic resonance imaging | Tau protein | Emission measurements | Resonance | Adults | Females | Alzheimers disease | Positron emission tomography | Hippocampus | Tracers | Index Medicus
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6. Full Text Defeating Alzheimer's disease and other dementias: a priority for European science and society
by Winblad, Bengt, Prof and Amouyel, Philippe, Prof and Andrieu, Sandrine, Prof and Ballard, Clive, Prof and Brayne, Carol, Prof and Brodaty, Henry, Prof and Cedazo-Minguez, Angel, PhD and Dubois, Bruno, Prof and Edvardsson, David, Prof and Feldman, Howard, Prof and Fratiglioni, Laura, Prof and Frisoni, Giovanni B, Prof and Gauthier, Serge, Prof and Georges, Jean, BA and Graff, Caroline, Prof and Iqbal, Khalid, Prof and Jessen, Frank, Prof and Johansson, Gunilla and Jönsson, Linus, MD and Kivipelto, Miia, Prof and Knapp, Martin, Prof and Mangialasche, Francesca, MD and Melis, René, PhD and Nordberg, Agneta, Prof and Rikkert, Marcel Olde, Prof and Qiu, Chengxuan, MD and Sakmar, Thomas P, Prof and Scheltens, Philip, Prof and Schneider, Lon S, Prof and Sperling, Reisa, Prof and Tjernberg, Lars O, PhD and Waldemar, Gunhild, Prof and Wimo, Anders, Prof and Zetterberg, Henrik, Prof and Institute of Neuroscience and Physiology and Sahlgrenska akademin and Göteborgs universitet and Gothenburg University and Sahlgrenska Academy and Institutionen för neurovetenskap och fysiologi
Lancet neurology, ISSN 1474-4422, 2016, Volume 15, Issue 5, pp. 455 - 532
Neurology | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Biomedical Research - organization & administration | Biomedical Research - economics | Dementia - therapy | Europe | Humans | Alzheimer Disease - therapy | Hospitals | Research institutes | Epidemiology | Alzheimer's disease | Neurophysiology | Caregivers | Enzymes | Biomedical research | Proxies | Cognitive ability | Studies | Disease prevention | Health care expenditures | Cost estimates | Quality | Aging | Biomarkers | Society | Alzheimers disease | Dementia | Index Medicus | Neurosciences | Physiology | Fysiologi | Neurovetenskaper
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