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JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2013, Volume 62, Issue 8, pp. 761 - 762
  Binding of the natriuretic proteins to the NPR-A receptor leads to enhanced lipolysis (ANP > BNP) (8) and adiponectin secretion (9), whereas binding to the... 
Cardiovascular | Internal Medicine | Studies | Heart | Plasma | Body mass index | Gastrointestinal surgery | Peptides
Journal Article
by van der Harst, Pim, MD, PhD and van Setten, Jessica, PhD and Verweij, Niek, PhD and Vogler, Georg, PhD and Franke, Lude, PhD and Maurano, Matthew T., PhD and Wang, Xinchen, BSc and Mateo Leach, Irene, PhD and Eijgelsheim, Mark, MD, PhD and Sotoodehnia, Nona, MD, MPH and Hayward, Caroline, PhD and Sorice, Rossella, PhD and Meirelles, Osorio, PhD and Lyytikäinen, Leo-Pekka, MD and Polašek, Ozren, MD, PhD and Tanaka, Toshiko, PhD and Arking, Dan E., PhD and Ulivi, Sheila, PhD and Trompet, Stella, PhD and Müller-Nurasyid, Martina, PhD and Smith, Albert V., PhD and Dörr, Marcus, MD and Kerr, Kathleen F., PhD and Magnani, Jared W., MD, MSc and Del Greco M., Fabiola, PhD and Zhang, Weihua, PhD and Nolte, Ilja M., PhD and Silva, Claudia T., MSc and Padmanabhan, Sandosh, MD, PhD and Tragante, Vinicius, PhD and Esko, Tõnu, PhD and Abecasis, Gonçalo R., PhD and Adriaens, Michiel E., PhD and Andersen, Karl, PhD and Barnett, Phil, PhD and Bis, Joshua C., PhD and Bodmer, Rolf, PhD and Buckley, Brendan M., MD, PhD and Campbell, Harry, MD and Cannon, Megan V., PhD and Chakravarti, Aravinda, PhD and Chen, Lin Y., MD, MS and Delitala, Alessandro, PhD and Devereux, Richard B., MD and Doevendans, Pieter A., MD, PhD and Dominiczak, Anna F., MD and Ferrucci, Luigi, MD, PhD and Ford, Ian, PhD and Gieger, Christian, PhD and Harris, Tamara B., PhD and Haugen, Eric and Heinig, Matthias, PhD and Hernandez, Dena G., MSc and Hillege, Hans L., MD, PhD and Hirschhorn, Joel N., MD, PhD and Hofman, Albert, MD, PhD and Hubner, Norbert, MD and Hwang, Shih-Jen, PhD and Iorio, Annamaria, MD and Kähönen, Mika, MD, PhD and Kellis, Manolis, PhD and Kolcic, Ivana, MD, PhD and Kooner, Ishminder K., MD, PhD and Kooner, Jaspal S., MBBS, MD and Kors, Jan A., PhD and Lakatta, Edward G., MD and Lage, Kasper, PhD and Launer, Lenore J., PhD and Levy, Daniel, MD and Lundby, Alicia, PhD and Macfarlane, Peter W., DSc and May, Dalit, MD and Meitinger, Thomas, MD, MSc and Metspalu, Andres, PhD and Nappo, Stefania, MSc and Naitza, Silvia, PhD and Neph, Shane, BS and Nord, Alex S., PhD and Nutile, Teresa, PhD and Okin, Peter M., MD and Olsen, Jesper V., PhD and Oostra, Ben A., PhD and Penninger, Josef M., MD and Pennacchio, Len A., PhD and Pers, Tune H., PhD and Perz, Siegfried, MSc and Peters, Annette, PhD and Pinto, Yigal M., MD, PhD and Pfeufer, Arne, MD, MSc and Pilia, Maria Grazia, PhD and Pramstaller, Peter P., MD and Prins, Bram P., MSc and Raitakari, Olli T., MD, PhD and Raychaudhuri, Soumya, MD, PhD and Rice, Ken M., PhD and Rossin, Elizabeth J., MD, PhD and Rotter, Jerome I., MD and Schafer, Sebastian, PhD and Schlessinger, David, PhD and Schmidt, Carsten O., PhD and ...
Journal of the American College of Cardiology, ISSN 0735-1097, 2016, Volume 68, Issue 13, pp. 1435 - 1448
Journal Article
Journal Article
Journal of Vascular Surgery Cases, ISSN 2352-667X, 2015, Volume 1, Issue 4, pp. 276 - 278
Pseudoxanthoma elasticum (PXE) is an inherited disease characterized by skin lesions, central blindness, and progressive peripheral occlusive disease. Severe... 
Surgery
Journal Article
by Holmes, Michael V., MSc and Simon, Tabassome, MD, PhD and Exeter, Holly J., PhD and Folkersen, Lasse, PhD and Asselbergs, Folkert W., MD, PhD and Guardiola, Montse, PhD and Cooper, Jackie A., MSc and Palmen, Jutta, MSc and Hubacek, Jaroslav A., DSc, PhD and Carruthers, Kathryn F., MPhil and Horne, Benjamin D., PhD, MPH and Brunisholz, Kimberly D., MST and Mega, Jessica L., MD, MPH and van Iperen, Erik P.A., MSc and Li, Mingyao, PhD and Leusink, Maarten, MSc and Trompet, Stella, PhD and Verschuren, Jeffrey J.W., MD, MSc and Hovingh, G. Kees, MD, PhD and Dehghan, Abbas, MD, PhD and Nelson, Christopher P., PhD and Kotti, Salma, PharmD, PhD and Danchin, Nicolas, MD, PhD and Scholz, Markus, PhD and Haase, Christiane L., PhD and Rothenbacher, Dietrich, MD and Swerdlow, Daniel I., MBBS, PhD and Kuchenbaecker, Karoline B., Dipl Psych, MSc and Staines-Urias, Eleonora, MD, MSc and Goel, Anuj, MSc and van 't Hooft, Ferdinand, MD, PhD and Gertow, Karl, PhD and de Faire, Ulf, MD, PhD and Panayiotou, Andrie G., PhD and Tremoli, Elena, PhD and Baldassarre, Damiano, PhD and Veglia, Fabrizio, PhD and Holdt, Lesca M., MD, PhD and Beutner, Frank, MD, PhD and Gansevoort, Ron T., MD, PhD and Navis, Gerjan J., MD, PhD and Mateo Leach, Irene, PhD and Breitling, Lutz P., MD and Brenner, Hermann, MD, MPH and Thiery, Joachim, MD, MBA and Dallmeier, Dhayana, MD and Franco-Cereceda, Anders, MD, PhD and Boer, Jolanda M.A., PhD and Stephens, Jeffrey W., PhD and Hofker, Marten H., PhD and Tedgui, Alain, PhD and Hofman, Albert, MD, PhD and Uitterlinden, André G., PhD and Adamkova, Vera, MD, PhD and Pitha, Jan, MD, PhD and Onland-Moret, N. Charlotte, PhD and Cramer, Maarten J., MD, PhD and Nathoe, Hendrik M., MD, PhD and Spiering, Wilko, MD, PhD and Klungel, Olaf H., PharmD, PhD and Kumari, Meena, PhD and Whincup, Peter H and Morrow, David A., MD and Braund, Peter S., MSc and Hall, Alistair S., PhD and Olsson, Anders G., MD, PhD and Doevendans, Pieter A., MD, PhD and Trip, Mieke D., MD, PhD and Tobin, Martin D., PhD and Hamsten, Anders, PhD and Watkins, Hugh, PhD and Koenig, Wolfgang, MD and Nicolaides, Andrew N., PhD and Teupser, Daniel, MD, PhD and Day, Ian N.M and Carlquist, John F., PhD and Gaunt, Tom R., PhD and Ford, Ian, PhD and Sattar, Naveed and Tsimikas, Sotirios, MD and Schwartz, Gregory G., MD PhD and Lawlor, Debbie A., PhD and Morris, Richard W., PhD and Sandhu, Manjinder S., PhD and Poledne, Rudolf, PhD and Maitland-van der Zee, Anke H., PhD and Khaw, Kay-Tee, MBBChir and Keating, Brendan J., PhD and van der Harst, Pim, MD, PhD and Price, Jackie F., MD and Mehta, Shamir R., MD, MSc and Yusuf, Salim, MBBS, DPhil and Witteman, Jaqueline C.M., PhD and Franco, Oscar H., MD, PhD and Jukema, J. Wouter, MD, PhD and de Knijff, Peter, PhD and Tybjaerg-Hansen, Anne, MD, DMSc and Rader, Daniel J., MD and Farrall, Martin, MD, PhD and Samani, Nilesh J., MD and ...
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2013, Volume 62, Issue 21, pp. 1966 - 1976
Objectives This study sought to investigate the role of secretory phospholipase A2 (sPLA2 )-IIA in cardiovascular disease. Background Higher circulating levels... 
Cardiovascular | Internal Medicine | drug development | epidemiology | genetics | cardiovascular diseases | Mendelian randomization | Studies | Cardiovascular disease | Heart attacks | Drug therapy | Mortality | Cholesterol
Journal Article
by Swerdlow, Daniel I, Dr and Preiss, David, Dr and Kuchenbaecker, Karoline B, MSc and Holmes, Michael V, PhD and Engmann, Jorgen E L, MSc and Shah, Tina, PhD and Sofat, Reecha, MD and Stender, Stefan, MD and Johnson, Paul C D, PhD and Scott, Robert A, PhD and Leusink, Maarten, MSc and Verweij, Niek, MD and Sharp, Stephen J, MSc and Guo, Yiran, PhD and Giambartolomei, Claudia, MSc and Chung, Christina, MSc and Peasey, Anne, PhD and Amuzu, Antoinette, MSc and Li, KaWah, MSc and Palmen, Jutta, MSc and Howard, Philip, MSc and Cooper, Jackie A, MSc and Drenos, Fotios, PhD and Li, Yun R, BSc and Lowe, Gordon, Prof and Gallacher, John, PhD and Stewart, Marlene C W, PhD and Tzoulaki, Ioanna, PhD and Buxbaum, Sarah G, PhD and van der A, Daphne L, PhD and Forouhi, Nita G, MRCP and Onland-Moret, N Charlotte, PhD and van der Schouw, Yvonne T, Prof and Schnabel, Renate B, MD and Hubacek, Jaroslav A, PhD and Kubinova, Ruzena, MD and Baceviciene, Migle, MD and Tamosiunas, Abdonas, Prof and Pajak, Andrzej, Prof and Topor-Madry, Romanvan, MD and Stepaniak, Urszula, PhD and Malyutina, Sofia, Prof and Baldassarre, Damiano, PhD and Sennblad, Bengt, PhD and Tremoli, Elena, Prof and de Faire, Ulf, Prof and Veglia, Fabrizio, PhD and Ford, Ian, Prof and Jukema, J Wouter, Prof and Westendorp, Rudi G J, Prof and de Borst, Gert Jan, MD and de Jong, Pim A, MD and Algra, Ale, Prof and Spiering, Wilko, MD and der Zee, Anke H Maitland-van, PhD and Klungel, Olaf H, PharmD and de Boer, Anthonius, Prof and Doevendans, Pieter A, Prof and Eaton, Charles B, Prof and Robinson, Jennifer G, Prof and Duggan, David, PhD and Kjekshus, John, Prof and Downs, John R, MD and Gotto, Antonio M, MD and Keech, Anthony C, MD and Marchioli, Roberto, MD and Tognoni, Gianni, MD and Sever, Peter S, Prof and Poulter, Neil R, Prof and Waters, David D, MD and Pedersen, Terje R, MD and Amarenco, Pierre, MD and Nakamura, Haruo, MD and McMurray, John J V, Prof and Lewsey, James D, PhD and Chasman, Daniel I, PhD and Ridker, Paul M, MD and Maggioni, Aldo P, Prof and Tavazzi, Luigi, Prof and Ray, Kausik K, Prof and Seshasai, Sreenivasa Rao Kondapally, MD and Manson, JoAnn E, Prof and Price, Jackie F, MD and Whincup, Peter H, Prof and Morris, Richard W, Prof and Lawlor, Debbie A, Prof and Smith, George Davey, Prof and Ben-Shlomo, Yoav, Prof and Schreiner, Pamela J, Prof and Fornage, Myriam, Prof and Siscovick, David S, Prof and Cushman, Mary, MD and Kumari, Meena, PhD and Wareham, Nick J, Prof and Verschuren, W M Monique, PhD and Redline, Susan, Prof and Patel, Sanjay R, MD and Whittaker, John C, Prof and Hamsten, Anders, Prof and Delaney, Joseph A, PhD and ... and MAGIC Consortium and InterAct Consortium and DIAGRAM Consortium
The Lancet, ISSN 0140-6736, 01/2015, Volume 385, Issue 9965, pp. 351 - 361
Journal Article
by Holmes, Michael V and Simon, Tabassome and Exeter, Holly J and Folkersen, Lasse and Asselbergs, Folkert W and Guardiola, Montse and Cooper, Jackie A and Palmen, Jutta and Hubacek, Jaroslav A and Carruthers, Kathryn F and Horne, Benjamin D and Brunisholz, Kimberly D and Mega, Jessica L and Van Iperen, Erik P. A and Li, Mingyao and Leusink, Maarten and Trompet, Stella and Verschuren, Jeffrey J. W and Hovingh, G. Kees and Dehghan, Abbas and Nelson, Christopher P and Kotti, Salma and Danchin, Nicolas and Scholz, Markus and Haase, Christiane L and Rothenbacher, Dietrich and Swerdlow, Daniel I and Kuchenbaecker, Karoline B and Staines-Urias, Eleonora and Goel, Anuj and van 't Hooft, Ferdinand and Gertow, Karl and de Faire, Ulf and Panayiotou, Anie G and Tremoli, Elena and Baldassarre, Damiano and Veglia, Fabrizio and Holdt, Lesca M and Beutner, Frank and Gansevoort, Ron T and Navis, Gerjan J and Mateo Leach, Irene and Breitling, Lutz P and Brenner, Hermann and Thiery, Joachim and Dallmeier, Dhayana and Franco-Cereceda, Anders and Boer, Jolanda M. A and Stephens, Jeffrey W and Hofker, Marten H and Tedgui, Alain and Hofman, Albert and Uitterlinden, Ane G and Adamkova, Vera and Pitha, Jan and Onland-Moret, N. Charlotte and Cramer, Maarten J and Nathoe, Henik M and Spiering, Wilko and Klungel, Olaf H and Kumari, Meena and Whincup, Peter H and Morrow, David A and Braund, Peter S and Hall, Alistair S and Olsson, Anders G and Doevendans, Pieter A and Trip, Mieke D and Tobin, Martin D and Hamsten, Anders and Watkins, Hugh and Koenig, Wolfgang and Nicolaides, Anew N and Teupser, Daniel and Day, Ian N. M and Carlquist, John F and Gaunt, Tom R and Ford, Ian and Sattar, Naveed and Tsimikas, Sotirios and Schwartz, Gregory G and Lawlor, Debbie A and Morris, Richard W and Sandhu, Manjinder S and Poledne, Rudolf and Maitland-van der Zee, Anke H and Khaw, Kay-Tee and Keating, Brendan J and van der Harst, Pim and Price, Jackie F and Mehta, Shamir R and Yusuf, Salim and Witteman, Jaqueline C. M and Franco, Oscar H and Jukema, J. Wouter and de Knijff, Peter and Tybjaerg-Hansen, Anne and Rader, Daniel J and Farrall, Martin and Samani, Nilesh J and ... and Avdelningen för kardiovaskulär medicin and Endokrinmedicinska kliniken and Linköpings universitet and Institutionen för medicin och hälsa and Hjärt- och Medicincentrum and Östergötlands Läns Landsting and Hälsouniversitetet
Journal of the American College of Cardiology, ISSN 0735-1097, 11/2013, Volume 62, Issue 21, pp. 1966 - 1976
Objectives This study sought to investigate the role of secretory phospholipase A(2) (sPLA(2))-IIA in cardiovascular disease. Background Higher circulating... 
CARDIAC & CARDIOVASCULAR SYSTEMS | EVENTS | METAANALYSIS | drug development | RISK | cardiovascular diseases | Mendelian randomization | ACUTE CORONARY SYNDROME | epidemiology | genetics | ENZYMES | SERUM-LEVELS | INHIBITOR | HEALTHY-MEN | ASSOCIATION | TEKNIKVETENSKAP | Engineering and Technology | Teknik och teknologier | TECHNOLOGY
Journal Article
Journal of the American College of Cardiology, ISSN 0735-1097, 03/2018, Volume 71, Issue 10, pp. 1117 - 1126
In pseudoxanthoma elasticum (PXE), low pyrophosphate levels may cause ectopic mineralization, leading to skin changes, visual impairment, and peripheral... 
bisphosphonates | PXE | etidronate | arterial calcification | AORTIC CALCIFICATION | CARDIAC & CARDIOVASCULAR SYSTEMS | ABCC6 GENE | VASCULAR CALCIFICATION | PYROPHOSPHATE | DISEASE | GENERALIZED ARTERIAL CALCIFICATION | MUTATIONS | CARDIOVASCULAR RISK | INFANCY | Peripheral Arterial Disease - etiology | Calcium - metabolism | Pseudoxanthoma Elasticum - physiopathology | Humans | Middle Aged | Tomography, X-Ray Computed - methods | Male | Pseudoxanthoma Elasticum - complications | Drug Monitoring - methods | Femur - diagnostic imaging | Calcium - blood | Etidronic Acid - pharmacokinetics | Etidronic Acid - adverse effects | Vascular Calcification - etiology | Peripheral Arterial Disease - blood | Phosphates - blood | Female | Vascular Calcification - diagnosis | Bone Density Conservation Agents - pharmacokinetics | Etidronic Acid - administration & dosage | Bone Density Conservation Agents - adverse effects | Pseudoxanthoma Elasticum - drug therapy | Treatment Outcome | Bone Density Conservation Agents - administration & dosage | Positron-Emission Tomography - methods | Vascular Calcification - drug therapy | Peripheral Arterial Disease - prevention & control | Bone Density - drug effects | Peripheral Arterial Disease - diagnosis | Pseudoxanthoma Elasticum - diagnosis | Aged | Prevention | Phosphates | Care and treatment | Phosphonates | Bones | Pseudoxanthoma elasticum | Density | Calcification (ectopic) | Femur | Calcium | Systematic review | Vascularization | Calcium (blood) | Computed tomography | Mineralization | Atherosclerosis | Skin diseases | Bone density | Safety | Drug therapy | Hypocalcemia | Positron emission | Vitamin deficiency | Preventive medicine | Patients | Calcium phosphates | Side effects | Sodium | Visual impairment | Etidronic acid | Arteriosclerosis | Calcification | Hyperphosphatemia | Skin | Adults | Positron emission tomography | Veins & arteries
Journal Article
Journal Article