X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (18) 18
aneuploidy (17) 17
cancer (12) 12
humans (12) 12
cell biology (11) 11
animals (9) 9
chromosomes (8) 8
genomes (8) 8
single-cell sequencing (8) 8
apoptosis (7) 7
dna-damage (7) 7
genetic aspects (7) 7
mutation (7) 7
cell cycle (6) 6
cell line, tumor (6) 6
deoxyribonucleic acid--dna (6) 6
dna sequencing (6) 6
genomic instability (6) 6
mice (6) 6
research (6) 6
tumors (6) 6
analysis (5) 5
article (5) 5
biology (5) 5
genetics & heredity (5) 5
male (5) 5
p53 (5) 5
single-cell analysis - methods (5) 5
biochemistry & molecular biology (4) 4
breast-cancer (4) 4
cells (4) 4
death (4) 4
evolution (4) 4
expression (4) 4
in-vivo (4) 4
mice, inbred c57bl (4) 4
nucleotide sequencing (4) 4
oncology (4) 4
recombination (4) 4
stem-cells (4) 4
tumorigenesis (4) 4
umcg approved (4) 4
alzheimer's disease (3) 3
biotechnology & applied microbiology (3) 3
brain (3) 3
copy number (3) 3
copy-number variation (3) 3
dna damage (3) 3
dna repair (3) 3
female (3) 3
homologous recombination (3) 3
immunology (3) 3
instability (3) 3
karyotype heterogeneity (3) 3
karyotypes (3) 3
mice, knockout (3) 3
mitosis (3) 3
multidisciplinary sciences (3) 3
neoplasms - genetics (3) 3
neurons (3) 3
p21 (3) 3
reverse transcriptase polymerase chain reaction (3) 3
sequence analysis, dna - methods (3) 3
spindle checkpoint (3) 3
time factors (3) 3
trail (3) 3
tumor evolution (3) 3
usage (3) 3
abridged index medicus (2) 2
alzheimer’s disease (2) 2
antineoplastic agents - pharmacology (2) 2
apoptosis - drug effects (2) 2
apoptosis - physiology (2) 2
apoptosis regulatory proteins (2) 2
apoptosis-inducing ligand (2) 2
blotting, western (2) 2
brca2 protein (2) 2
cancer cells (2) 2
caspase 8 (2) 2
cell culture (2) 2
cell cycle - physiology (2) 2
cell death (2) 2
cell line (2) 2
cell survival (2) 2
cell-death (2) 2
checkpoint (2) 2
chemotherapeutic-agents (2) 2
chromosomal instability (2) 2
chromosome aberrations (2) 2
chromosome instability (2) 2
chromosome mis-segregation (2) 2
cohesion fatigue (2) 2
copy number detection (2) 2
cyclin-dependent kinase inhibitor p21 (2) 2
dna (2) 2
dna replication (2) 2
dna-replication (2) 2
double-strand break (2) 2
down-regulation (2) 2
dr4 (2) 2
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Molecular Cytogenetics, ISSN 1755-8166, 07/2019, Volume 12
Journal Article
by Chaisson, Mark J P and Sanders, Ashley D and Zhao, Xuefang and Malhotra, Ankit and Porubsky, David and Rausch, Tobias and Gardner, Eugene J and Roiguez, Oscar L and Guo, Li and Collins, Ryan L and Fan, Xian and Wen, Jia and Handsaker, Robert E and Fairley, Susan and Kronenberg, Zev N and Kong, Xiangmeng and Hormozdiari, Fereydoun and Lee, Dillon and Wenger, Aaron M and Hastie, Alex R and Antaki, Danny and Anantharaman, Thomas and Audano, Peter A and Brand, Harrison and Cantsilieris, Stuart and Cao, Han and Cerveira, Eliza and Chen, Chong and Chen, Xintong and Chin, Chen-Shan and Chong, Zechen and Chuang, Nelson T and Lambert, Christine C and Church, Deanna M and Clarke, Laura and Farrell, Anew and Flores, Joey and Galeev, Timur and Gorkin, David U and Gujral, Madhusudan and Guryev, Victor and Heaton, William Haynes and Korlach, Jonas and Kumar, Sushant and Kwon, Jee Young and Lam, Ernest T and Lee, Jong Eun and Lee, Joyce and Lee, Wan-Ping and Lee, Sau Peng and Li, Shantao and Marks, Patrick and Viaud-Martinez, Karine and Meiers, Sascha and Munson, Katherine M and Navarro, Fabio C P and Nelson, Bradley J and Nodzak, Conor and Noor, Amina and Kyriazopoulou-Panagiotopoulou, Sofia and Pang, Andy W C and Qiu, Yunjiang and Rosanio, Gabriel and Ryan, Mallory and Stütz, Aian and Spierings, Diana C J and Ward, Alistair and Welch, AnneMarie E and Xiao, Ming and Xu, Wei and Zhang, Chengsheng and Zhu, Qihui and Zheng-Bradley, Xiangqun and Lowy, Ernesto and Yakneen, Sergei and McCarroll, Steven and Jun, Goo and Ding, Li and Koh, Chong Lek and Ren, Bing and Flicek, Paul and Chen, Ken and Gerstein, Mark B and Kwok, Pui-Yan and Lansdorp, Peter M and Marth, Gabor T and Sebat, Jonathan and Shi, Xinghua and Bashir, Ali and Ye, Kai and Devine, Scott E and Talkowski, Michael E and Mills, Ryan E and Marschall, Tobias and Korbel, Jan O and Eichler, Evan E and Lee, Charles
Nature Communications, ISSN 2041-1723, 04/2019, Volume 10, Issue 1, pp. 1784 - 16
The incomplete identification of structural variants (SVs) from whole-genome sequencing data limits studies of human genetic diversity and disease association.... 
MICRODELETION | GENETIC-VARIATION | RECOMBINATION | ACCURATE | SPERM CELLS | MAPS | MULTIDISCIPLINARY SCIENCES | SEGMENTAL DUPLICATIONS | DIVERSITY | RETROTRANSPOSITION | COPY-NUMBER VARIATION | Metal oxides | Energy transfer | Metals
Journal Article
Nature Communications, ISSN 2041-1723, 01/2018, Volume 9, Issue 1, pp. 1 - 12
Journal Article
Cell Reports, ISSN 2211-1247, 06/2017, Volume 19, Issue 12, pp. 2423 - 2431
The presence of an abnormal karyotype has been shown to be profoundly detrimental at the cellular and organismal levels but is an overt hallmark of cancer.... 
aneuploidy | single-cell sequencing | chromosome missegregation | p53 | STEM-CELLS | INSTABILITY | DNA-DAMAGE | PROLIFERATION | INHIBITOR | CANCER | TUMORIGENESIS | GSK923295 | MURINE | CELL BIOLOGY | Tumor Suppressor Protein p53 - physiology | Cell Line | Cell Cycle Checkpoints | Chromosome Segregation | Neoplasms - genetics | Humans | Chromosome Aberrations | Aneuploidy
Journal Article
Genome Biology, ISSN 1465-6906, 05/2016, Volume 17, Issue 1, p. 115
Journal Article
Nature communications, 01/2018, Volume 9, Issue 1, p. 271
Bloom syndrome is a cancer predisposition disorder caused by mutations in the BLM helicase gene. Cells from persons with Bloom syndrome exhibit striking... 
Journal Article
Methods in molecular biology (Clifton, N.J.), ISSN 1064-3745, 2019, Volume 1896, pp. 159 - 190
High-throughput next generation sequencing karyotyping has emerged as a powerful tool for the detection of genomic heterogeneity in normal tissues and cancers.... 
Aneuploidy | Library preparation | Copy number alterations | Single-cell whole genome sequencing
Journal Article
Cancer Cell, ISSN 1535-6108, 03/2019, Volume 35, Issue 3, pp. 519 - 533.e8
Inhibitors of poly(ADP-ribose) polymerase (PARP) have demonstrated efficacy in women with -mutant ovarian cancer. However, only 15%–20% of ovarian cancers... 
HGSOC | PARG | DNA damage | γH2AX | TIMELESS | PARP | replication catastrophe | CHK1 | ONCOLOGY | DOUBLE-BLIND | RESTART | HISTONE H2AX | MAINTENANCE THERAPY | FORKS | DAMAGE | ATR | REVEALS | CELL BIOLOGY | DNA replication | Analysis | DNA | Cancer cells | Genetic aspects | Drug discovery | Research institutes | Sugars | Ovarian cancer | Monosaccharides | Cancer
Journal Article
ONCOGENE, ISSN 0950-9232, 02/2019, Volume 38, Issue 6, pp. 852 - 867
Journal Article
International Journal of Biochemistry and Cell Biology, ISSN 1357-2725, 01/2018, Volume 94, pp. 146 - 150
The use of single-cell DNA sequencing (sc-seq) techniques for the diagnosis, prognosis and treatment of cancer is a rapidly developing field. Sc-seq research... 
Tumor evolution | Single-cell sequencing | Circulating tumor cells | Intra-tumor heterogeneity | BREAST-CANCER | NUCLEOTIDE | LUNG-CANCER | ANEUPLOIDY | ORIGIN | EVOLUTION | CIRCULATING TUMOR-CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL BIOLOGY | Usage | Analysis | Genomics | Development and progression | Genetic aspects | Metastasis | Nucleotide sequencing | Cancer | DNA sequencing
Journal Article