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1. Full Text Bone marrow-on-a-chip replicates hematopoietic niche physiology in vitro
by Torisawa, Yu-Suke and Spina, Catherine S and Mammoto, Tadanori and Mammoto, Akiko and Weaver, James C and Tat, Tracy and Collins, James J and Ingber, Donald E
Nature methods, ISSN 1548-7091, 2014, Volume 11, Issue 6, pp. 663 - 669
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Biochemical Research Methods | Science & Technology | Microfluidic Analytical Techniques | Animals | Bone Marrow - chemistry | Hematopoiesis | Hematopoietic Stem Cells - physiology | Mice | Cell Culture Techniques | Bone Marrow - physiology | Bioengineering | Usage | Animal models in research | Physiological aspects | Bone marrow | Research | Hematopoietic stem cells | Cellular biology | Biomimetics | Biomedical engineering | Index Medicus
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2. Full Text Antibiotic treatment expands the resistance reservoir and ecological network of the phage metagenome
by Modi, Sheetal R and Lee, Henry H and Spina, Catherine S and Collins, James J
Nature (London), ISSN 0028-0836, 2013, Volume 499, Issue 7457, pp. 219 - 222
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Metagenome - drug effects | Aerobiosis | Drug Resistance, Microbial - drug effects | Bacteriophages - drug effects | Genome, Viral - genetics | Ciprofloxacin - pharmacology | Drug Resistance, Microbial - genetics | Gene Transfer, Horizontal - drug effects | Host Specificity - drug effects | Symbiosis - genetics | Bacteriophages - isolation & purification | Feces - microbiology | Feces - virology | Metagenome - genetics | Animals | Genes, Viral - drug effects | Genes, Viral - genetics | Bacteriophages - genetics | Female | Ampicillin - pharmacology | Anti-Bacterial Agents - pharmacology | Mice | Symbiosis - drug effects | Gene Transfer, Horizontal - genetics | Bacteriophages | Drug resistance in microorganisms | Complications and side effects | Antibiotics | Physiological aspects | Genetic aspects | Health aspects | Proteins | Drinking water | Databases | Microbiology | Protein synthesis | Ecosystems | Genes | Genetic engineering | Genomes | Drug resistance | Stress | Index Medicus
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3. Full Text Quantification of microcirculatory blood flow: A sensitive and clinically relevant prognostic marker in murine models of sepsis
by Sand, Claire A and Starr, Anna and Wilder, Catherine D. E and Rudyk, Olena and Spina, Domenico and Thiemermann, Christoph and Treacher, David F and Nandi, Manasi
Journal of applied physiology (1985), ISSN 8750-7587, 02/2015, Volume 118, Issue 3, pp. 344 - 354
Microcirculation | Sepsis | Septic shock | Animal models of cardiovascular disease | Physiology | Sport Sciences | Life Sciences & Biomedicine | Science & Technology | Cardiac Output - physiology | Prognosis | Mice, Inbred C57BL | Male | Biomarkers - blood | Hemodynamics - physiology | Cecum - pathology | Microcirculation - physiology | Animals | Sepsis - pathology | Blood Pressure - physiology | Mice | Regional Blood Flow - physiology | Disease Models, Animal | Cardiovascular system | Pathogenesis | Medical prognosis | Biomarkers | Blood pressure | Index Medicus | septic shock | microcirculation | animal models of cardiovascular disease | sepsis
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4. Full Text Potentiating antibacterial activity by predictably enhancing endogenous microbial ROS production
by Brynildsen, Mark P and Winkler, Jonathan A and Spina, Catherine S and MacDonald, I Cody and Collins, James J
Nature biotechnology, ISSN 1087-0156, 02/2013, Volume 31, Issue 2, pp. 160 - 165
Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Oxidants - pharmacology | Reactive Oxygen Species - metabolism | Oxidation-Reduction | Escherichia coli - drug effects | Humans | Hydrogen Peroxide - pharmacology | Microbial Sensitivity Tests | Anti-Bacterial Agents - therapeutic use | Escherichia coli - genetics | Escherichia coli - metabolism | Anti-Bacterial Agents - pharmacology | Drug Resistance, Bacterial - drug effects | Drug Resistance, Bacterial - genetics | Physiological aspects | Drug resistance in microorganisms | Reactive oxygen species | Antibiotics | Health aspects | Escherichia coli | Drug resistance | Public health | Index Medicus
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5. Androgen deprivation therapy and radiation therapy for prostate cancer: The mechanism underlying therapeutic synergy
by Spina, Catherine S
Translational cancer research, ISSN 2218-676X, 07/2018, Volume 7, pp. S695 - S703
Synergy | Androgen deprivation therapy (ADT) | Prostate cancer | Radiation | Life Sciences & Biomedicine | Oncology | Science & Technology
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6. Full Text Multiple mechanisms disrupt the let-7 microRNA family in neuroblastoma
by Powers, John T and Tsanov, Kaloyan M and Pearson, Daniel S and Roels, Frederik and Spina, Catherine S and Ebright, Richard and Seligson, Marc and De Soysa, Yvanka and Cahan, Patrick and Theißen, Jessica and Tu, Ho-Chou and Han, Areum and Kurek, Kyle C and Lapier, Grace S and Osborne, Jihan K and Ross, Samantha J and Cesana, Marcella and Collins, James J and Berthold, Frank and Daley, George Q
Nature (London), ISSN 0028-0836, 2016, Volume 535, Issue 7611, pp. 246 - 251
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Chromosome Deletion | Oncogene Proteins - genetics | RNA-Binding Proteins - genetics | Humans | Neuroblastoma - genetics | 3' Untranslated Regions - genetics | MicroRNAs - metabolism | Xenograft Model Antitumor Assays | Animals | Gene Deletion | Female | Gene Amplification - genetics | Mice | MicroRNAs - genetics | Models, Genetic | N-Myc Proto-Oncogene Protein | Nuclear Proteins - genetics | Genes, Neoplasm - genetics | Neuroblastoma - pathology | Genetic aspects | MicroRNA | Neuroblastoma | Health aspects | Pathogenesis | Biosynthesis | Proteins | Cell growth | Rodents | MicroRNAs | Protein expression | Mutation | Chromosomes | Binding sites | Tumors | Cancer | Index Medicus
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7. Full Text Increased rates of immunosuppressive treatment and hospitalization after checkpoint inhibitor therapy in cancer patients with autoimmune disease
by Bender, David Andrew and Heilbroner, Samuel P and Wang, Tony J C and Shu, Catherine A and Hyde, Brigham and Spina, Catherine and Cheng, Simon K
Journal for immunotherapy of cancer, 12/2020, Volume 8, Issue 2
Oncology | Immunology | Life Sciences & Biomedicine | Science & Technology | Index Medicus
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8. Full Text Silver enhances antibiotic activity against gram-negative bacteria
by RubenMorones-Ramirez, Jose and Winkler, Jonathan A and Spina, Catherine S and Collins, James J
Science translational medicine, ISSN 1946-6234, 06/2013, Volume 5, Issue 190, pp. 190ra81 - 190ra81
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Cell Biology | Research & Experimental Medicine | Biofilms - drug effects | Disulfides - metabolism | Gram-Negative Bacteria - ultrastructure | Silver - pharmacology | Gram-Negative Bacterial Infections - pathology | Microbial Viability - drug effects | Humans | Gram-Negative Bacterial Infections - drug therapy | Hydroxyl Radical - metabolism | Iron - metabolism | Drug Synergism | Gram-Negative Bacterial Infections - microbiology | Microbial Sensitivity Tests | Anti-Bacterial Agents - therapeutic use | Gram-Negative Bacteria - drug effects | Animals | Silver - therapeutic use | Cell Membrane Permeability - drug effects | Silver - toxicity | Anti-Bacterial Agents - pharmacology | Mice | Gram-Negative Bacteria - physiology | Disease Models, Animal | Index Medicus
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9. Full Text The First White House Library: A History and Annotated Catalogue. Edited by Catherine M. Parisian. University Park: Pennsylvania State University Press, 2010. xvi, 398p. ISBN 978-0271037134. $55.00
by Spina, Carli
RBM : a journal of rare books, manuscripts, and cultural heritage, ISSN 1529-6407, 09/2011, Volume 12, Issue 2, pp. 133 - 135
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10. Full Text Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK
by Voysey, Merryn and Madhi, Shabir A and Weckx, Lily Y and Folegatti, Pedro M and Aley, Parvinder K and Angus, Brian and Barnabas, Shaun L and Briner, Carmen and Collins, Andrea M and Cutland, Clare L and Darton, Thomas C and Dheda, Keertan and Duncan, Christopher J A and Fairlie, Lee and Faust, Saul N and Ferreira, Daniela M and Finn, Adam and Goodman, Anna L and Heath, Paul T and Hill, Catherine and Hill, Helen and Hirsch, Ian and Hodgson, Susanne H C and Izu, Alane and Jackson, Susan and Koen, Anthonet and Kwatra, Gaurav and Lazarus, Rajeka and Lawrie, Alison M and Libri, Vincenzo and Mallory, Raburn and Milan, Eveline P and Minassian, Angela M and McGregor, Alastair and Morrison, Hazel and Mujadidi, Yama F and Nana, Anusha and Padayachee, Sherman D and Plested, Emma and Pollock, Katrina M and Ramasamy, Maheshi N and Schwarzbold, Alexandre V and Singh, Nisha and Smith, Andrew and Sprinz, Eduardo and Tarrant, Richard and Thomson, Emma C and Turner, David P J and Vekemans, Johan and Villafana, Tonya L and Williams, Christopher J and Hill, Adrian V S and Lambe, Teresa and Gilbert, Sarah C and Aban, Marites and Abayomi, Fatola and Abeyskera, Kushala and Aboagye, Jeremy and Adam, Matthew and Adams, Kirsty and Adamson, James and Adelaja, Yemi A and Adlou, Syed and Ahmed, Khatija and Akhalwaya, Yasmeen and Alcock, Andrew and Ali, Aabidah and Allen, Lauren and Alves, Mariana P.S and Amorim, Fabio and Andritsou, Foteini and Anslow, Rachel and Arbe-Barnes, Edward H and Ariaans, Mark P and Arns, Beatriz and Arruda, Laiana and Azi, Lorena and Babbage, Gavin and Bailey, Catherine and Baker, Kenneth F and Baker, Megan and Baker, Philip and Baleanu, Ioana and Bara, Anna and Barbosa, Marcella A.S and Barlow, Gavin D and Barnes, Eleanor and Barr, Andrew S and Barrett, Jordan R and Barrett, Jessica and Batten, Alexander and Beadon, Kirsten and Beckley, Rebecca and Belij-Rammerstorfer, Sandra and Bell, Jonathan and Bellei, Nancy and Belton, Sue and Bermejo, Laura and Berrie, Eleanor and Berzenyi, Daniella and ... and Oxford COVID Vaccine Trial Group
The Lancet (British edition), ISSN 0140-6736, 01/2021, Volume 397, Issue 10269, pp. 99 - 111
Epidemics | Regulatory agencies | Pandemics | Statistical analysis | Severe acute respiratory syndrome | Viral diseases | Innovations | Clinical trials | Research facilities | Vaccines | Nucleic acids | Coronaviruses | Regression analysis | Severe acute respiratory syndrome coronavirus 2 | COVID-19 | Charities | Regression models | Robustness (mathematics) | Older people | Safety | Index Medicus | Abridged Index Medicus
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11. Full Text Bactericidal antibiotics induce mitochondrial dysfunction and oxidative damage in mammalian cells
by Kalghatgi, Sameer and Spina, Catherine S and Costello, James C and Liesa, Marc and Morones-Ramirez, J. Ruben and Slomovic, Shimyn and Molina, Anthony and Shirihai, Orian S and Collins, James J
Science translational medicine, ISSN 1946-6234, 07/2013, Volume 5, Issue 192, pp. 192ra85 - 192ra85
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Cell Biology | Research & Experimental Medicine | Immunohistochemistry | Cell Line | Reactive Oxygen Species - metabolism | Humans | Mice, Inbred C57BL | Cells, Cultured | Mitochondria - metabolism | Quinolones - pharmacology | Mitochondria - drug effects | Hydrogen Peroxide - metabolism | beta-Lactams - pharmacology | Animals | Quinolones - adverse effects | Adenosine Triphosphate - metabolism | Superoxides - metabolism | beta-Lactams - adverse effects | Female | Anti-Bacterial Agents - adverse effects | Anti-Bacterial Agents - pharmacology | Mice | Oxidative Stress - drug effects | Aminoglycosides - adverse effects | Aminoglycosides - pharmacology | Index Medicus
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