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Virtual Reality, ISSN 1359-4338, 03/2016, Volume 351, Issue 6278, pp. 1208 - 1213
Journal Article
Cancer Research, ISSN 0008-5472, 10/2013, Volume 73, Issue 19, pp. 6024 - 6035
HER2/HER3 dimerization resulting from overexpression of HER2 or neuregulin (NRG1) in cancer leads to HER3-mediated oncogenic activation of phosphoinositide... 
BREAST-CANCER | EXTRACELLULAR REGION | COMPLEX | DOMAIN | ACTIVATION | ERBB3 | ONCOLOGY | AFFINITY | CRYSTAL-STRUCTURE | FACTOR RECEPTOR | TRASTUZUMAB RESISTANCE | Receptor, ErbB-3 - metabolism | Immunoprecipitation | Humans | Protein Conformation - drug effects | Receptor, ErbB-2 - metabolism | Immunoblotting | Receptor, ErbB-3 - chemistry | Breast Neoplasms - metabolism | Receptor, Epidermal Growth Factor - metabolism | Receptor, ErbB-3 - immunology | Antibodies, Monoclonal, Humanized - pharmacology | Female | Receptor, ErbB-2 - antagonists & inhibitors | Receptor, ErbB-2 - immunology | Phosphorylation - drug effects | Tumor Cells, Cultured | Proto-Oncogene Proteins c-akt - metabolism | Signal Transduction | Receptor, ErbB-3 - antagonists & inhibitors | Survival Rate | Mice, SCID | Xenograft Model Antitumor Assays | Animals | Breast Neoplasms - pathology | Mice, Nude | Neuregulin-1 - metabolism | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Breast Neoplasms - mortality | Mice, Inbred NOD | Cell Proliferation - drug effects | Mice | Mice, Inbred BALB C | Protein Multimerization - drug effects | Proto-Oncogene Proteins c-akt - antagonists & inhibitors | BASIC BIOLOGICAL SCIENCES | 60 APPLIED LIFE SCIENCES | PI-3 kinase | NRG | ligand-independent | Antibody | neuregulin | SCCHN | EGFR | resistance | feedback | HER | PIK3CA | cancer | HER2 | HER3 | ligand-dependent
Journal Article
Diabetes technology & therapeutics, ISSN 1520-9156, 08/2019
Background The GRADE study has enrolled a racially and ethnically diverse population with type 2 diabetes (T2D), performed extensive phenotyping, and randomly... 
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 01/2012, Volume 56, Issue 1, pp. 17 - 27
Journal Article
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 06/2017, Volume 60, Issue 12, pp. 5002 - 5014
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 03/2017, Volume 60, Issue 5, pp. 2155 - 2161
While adding the structural features that are more favored by on-target activity is the more common strategy in selectivity optimization, the opposite strategy... 
60 APPLIED LIFE SCIENCES | INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
Journal Article
JOURNAL OF MEDICINAL CHEMISTRY, ISSN 0022-2623, 03/2017, Volume 60, Issue 5, pp. 2155 - 2161
While adding the structural features that are more favored by on-target activity is the more common strategy in selectivity optimization, the opposite strategy... 
TARGET | CHEMISTRY, MEDICINAL | CANCER | DISCOVERY | Crystallography, X-Ray | Enzyme Inhibitors - chemistry | Leucine Zippers | Enzyme Inhibitors - pharmacology | Protein-Serine-Threonine Kinases - antagonists & inhibitors
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 05/2016, Volume 59, Issue 10, pp. 4711 - 4723
Journal Article
Cancer Research, ISSN 0008-5472, 07/2016, Volume 76, Issue 14_Supplement, pp. LB - 017-LB-017
Metabolic genes are increasingly recognized as targets of somatic genetic alteration in human cancer often leading to profound changes in intracellular... 
Journal Article
Journal of Virology, ISSN 0022-538X, 04/2008, Volume 82, Issue 7, pp. 3490 - 3499
Journal Article
PLoS Biology, ISSN 1544-9173, 06/2006, Volume 4, Issue 6
  Herpes simplex virus type-1 expresses a heterodimeric Fc receptor, gE-gI, on the surfaces of virions and infected cells that binds the Fc region of host... 
Proteins | Medical research | Experiments | Binding sites | Crystal structure
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 03/2000, Volume 275, Issue 12, pp. 9011 - 9018
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 01/2012, Volume 56, Issue 1, pp. 17 - 27
Journal Article