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science & technology (9) 9
life sciences & biomedicine (7) 7
evolution (6) 6
evolutionary biology (5) 5
mutation (5) 5
biochemistry & molecular biology (4) 4
adaptation (3) 3
biology (3) 3
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science (2) 2
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acetylation (1) 1
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1. Full Text The Effect on Data Reproducibility of Dummy Modification
by Sprouffske, J. F., author
SAE technical paper series, Volume 710847.
Anthropometric test devices | Crash research
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2. Full Text PAX8 activates metabolic genes via enhancer elements in Renal Cell Carcinoma
by Bleu, Melusine and Gaulis, Swann and Lopes, Rui and Sprouffske, Kathleen and Apfel, Verena and Holwerda, Sjoerd and Pregnolato, Marco and Yildiz, Umut and Cordo, Valentina and Dost, Antonella F. M and Knehr, Judith and Carbone, Walter and Lohmann, Felix and Lin, Charles Y and Bradner, James E and Kauffmann, Audrey and Tordella, Luca and Roma, Guglielmo and Galli, Giorgio G
Nature communications, ISSN 2041-1723, 08/2019, Volume 10, Issue 1, pp. 3739 - 10
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | PAX8 Transcription Factor - genetics | RNA, Small Interfering - genetics | Cell Proliferation - genetics | Kidney Neoplasms - genetics | Humans | Carcinoma, Renal Cell - genetics | Promoter Regions, Genetic - genetics | Ceruloplasmin - genetics | RNA Interference | Cell Line, Tumor | Ceruloplasmin - metabolism | Biomarkers, Tumor - genetics | Enhancer Elements, Genetic - genetics | Acetylation | Histones - metabolism | Gene Expression Regulation, Neoplastic - genetics | Ceruloplasmin | Ferroxidase | Circuits | Genes | Gene expression | Metabolism | Kinases | Screens | Enhancers | Renal cell carcinoma | Kidney cancer | Biomarkers | Metabolic pathways | Active control | Pax8 protein | Index Medicus
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3. Full Text Effect of population size and mutation rate on the evolution of RNA sequences on an adaptive landscape determined by RNA folding
by Vahdati, Ali R and Sprouffske, Kathleen and Wagner, Andreas
International journal of biological sciences, ISSN 1449-2288, 09/2017, Volume 13, Issue 9, pp. 1138 - 1151
Population size | Fitness landscape | RNA secondary structure | Rate of adaptation | Biochemistry & Molecular Biology | Biology | Life Sciences & Biomedicine - Other Topics | Life Sciences & Biomedicine | Science & Technology | Adaptive structures | Populations | Biological evolution | Population number | Population studies | Mutation rates | Secondary structure | Ribonucleic acid--RNA | Gene sequencing | Population | Evolution | Mutation | Evolution & development | Protein structure | Folding | Fitness | Index Medicus
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4. Full Text Genetic heterogeneity and clonal evolution during metastasis in breast cancer patient-derived tumor xenograft models
by Sprouffske, Kathleen and Kerr, Grainne and Li, Cheng and Prahallad, Anirudh and Rebmann, Ramona and Waehle, Verena and Naumann, Ulrike and Bitter, Hans and Jensen, Michael R and Hofmann, Francesco and Brachmann, Saskia M and Ferretti, Stéphane and Kauffmann, Audrey
Computational and structural biotechnology journal, ISSN 2001-0370, 2020, Volume 18, pp. 323 - 331
Clonal evolution | Heterogeneity | Breast cancer | Metastasis | Patient derived xenograft models | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology
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5. Full Text High mutation rates limit evolutionary adaptation in Escherichia coli
by Sprouffske, Kathleen and Aguílar-Rodríguez, José and Sniegowski, Paul and Wagner, Andreas
PLoS genetics, ISSN 1553-7390, 04/2018, Volume 14, Issue 4, pp. e1007324 - e1007324
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Genetic Variation | Algorithms | Genetic Fitness | Genetics, Population - methods | Adaptation, Physiological - genetics | Escherichia coli - genetics | Selection, Genetic | Mutation Rate | Models, Genetic | Whole Genome Sequencing - methods | Evolution, Molecular | Genetic aspects | Gene mutations | Escherichia coli | Analysis | Laboratories | Funding | Genomes | Mutation rates | Genetic diversity | Population genetics | Studies | E coli | Antibiotics | Evolutionary biology | Alleles | Evolution | Environmental studies | Mutation | Bioinformatics | Evolution & development | Supervision | Adaptation | Tumors | Fitness | Index Medicus
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6. Full Text Growthcurver: An R package for obtaining interpretable metrics from microbial growth curves
by Sprouffske, Kathleen and Wagner, Andreas
BMC bioinformatics, ISSN 1471-2105, 2016, Volume 17, Issue 1, pp. 172 - 172
Logistic | Experimental evolution | Growth curve | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Biochemical Research Methods | Science & Technology | Mathematical & Computational Biology | Programming Languages | Logistic Models | Bacteria - growth & development | Software | Computational Biology | Databases, Factual | Physiological aspects | Microbial growth | Usage | Research | Applications software | Index Medicus
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7. Full Text Application of simultaneous selective pressures slows adaptation
by Merlo, Lauren M. F and Sprouffske, Kathleen and Howard, Taylor C and Gardiner, Kristin L and Caulin, Aleah F and Blum, Steven M and Evans, Perry and Bedalov, Antonio and Sniegowski, Paul D and Maley, Carlo C
Evolutionary applications, ISSN 1752-4571, 08/2020, Volume 13, Issue 7, pp. 1615 - 1625
cancer therapy | functional interference | adaptation | slowing evolution | clonal interference | Life Sciences & Biomedicine | Evolutionary Biology | Science & Technology | Statistical analysis | Glucose | Drug resistance | Experiments | Infectious diseases | Histidine | Population | Evolution | Nutrients | Mutation | Uracil | Cancer | Adaptation | Fitness
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8. Full Text Assessing the benefits of horizontal gene transfer by laboratory evolution and genome sequencing
by Chu, Hoi Yee and Sprouffske, Kathleen and Wagner, Andreas
BMC evolutionary biology, ISSN 1471-2148, 04/2018, Volume 18, Issue 1, pp. 54 - 54
Novel nutrient adaptation | Experimental evolution | Horizontal gene transfer | Genetics & Heredity | Life Sciences & Biomedicine | Evolutionary Biology | Science & Technology | Genetic transformation | Escherichia coli | Evolution | Genetic aspects | Research | Nucleotide sequencing | DNA sequencing | Index Medicus
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9. Full Text Solving the puzzle of metastasis: The evolution of cell migration in neoplasms
by Chen, Jun and Sprouffske, Kathleen and Huang, Qihong and Maley, Carlo C
PloS one, ISSN 1932-6203, 2011, Volume 6, Issue 4, pp. e17933 - e17933
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Models, Theoretical | Neoplasm Metastasis | Blood Vessels - pathology | Humans | Neovascularization, Pathologic | Neoplasms - blood supply | Neoplasms - pathology | Cell Movement | Emigration and immigration | Metastasis | Occlusion | Leukocyte migration | Theory | Brain cancer | Genomics | Biology | Kinases | Cancer therapies | Neoplasms | Metastases | Angiogenesis | Heterogeneity | Cell cycle | Evolution | Nutrients | Edema | Oxygen | Computer simulation | Cloning | Emigration | Blood vessels | Medicine | Mutation | Cell migration | Tumors | Index Medicus
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