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science & technology (77) 77
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1. Full Text The genetic basis of kidney cancer: a metabolic disease
by Linehan, W. Marston and Srinivasan, Ramaprasad and Schmidt, Laura S
Nature reviews. Urology, ISSN 1759-4812, 05/2010, Volume 7, Issue 5, pp. 277 - 285
Life Sciences & Biomedicine | Urology & Nephrology | Science & Technology | Kidney Neoplasms - genetics | Humans | Carcinoma, Renal Cell - genetics | Proto-Oncogene Proteins - genetics | Fumarate Hydratase - genetics | Proto-Oncogene Proteins c-met - genetics | Receptors, Growth Factor - genetics | Citric Acid Cycle - genetics | Succinate Dehydrogenase - genetics | Tuberous Sclerosis Complex 2 Protein | Tumor Suppressor Proteins - genetics | Tuberous Sclerosis Complex 1 Protein | Von Hippel-Lindau Tumor Suppressor Protein - genetics | Mutation | Carcinoma, Renal Cell - drug therapy | Kidney Neoplasms - drug therapy | Care and treatment | Transcription factors | Gene mutations | Kidney cancer | Physiological aspects | Cellular signal transduction | Genetic aspects | Research | Health aspects | Index Medicus
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2. Full Text Kidney cancer in 2017: Challenging and refining treatment paradigms
by Ball, Mark W and Srinivasan, Ramaprasad
Nature reviews. Urology, ISSN 1759-4812, 02/2018, Volume 15, Issue 2, pp. 77 - 78
Development and progression | Care and treatment | Kidney cancer | Index Medicus
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3. Full Text Challenging and refining treatment paradigms
by Ball, Mark W and Srinivasan, Ramaprasad
Nature reviews. Urology, ISSN 1759-4812, 02/2018, Volume 15, Issue 2, pp. 77 - U21
Life Sciences & Biomedicine | Urology & Nephrology | Science & Technology
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4. Full Text Phase II and Biomarker Study of the Dual MET/VEGFR2 Inhibitor Foretinib in Patients With Papillary Renal Cell Carcinoma
by Toni K. Choueiri and Ulka Vaishampayan and Jonathan E. Rosenberg and Theodore F. Logan and Andrea L. Harzstark and Ronald M. Bukowski and Brian I. Rini and Sandy Srinivas and Mark N. Stein and Laurel M. Adams and Lone H. Ottesen and Kevin H. Laubscher and Laurie Sherman and David F. McDermott and Naomi B. Haas and Keith T. Flaherty and Robert Ross and Peter Eisenberg and Paul S. Meltzer and Maria J. Merino and Donald P. Bottaro and W. Marston Linehan and Ramaprasad Srinivasan
Journal of clinical oncology, ISSN 0732-183X, 01/2013, Volume 31, Issue 2, pp. 181 - 186
Life Sciences & Biomedicine | Oncology | Science & Technology | Tumors of the urinary system | Nephrology. Urinary tract diseases | Biological and medical sciences | Kidneys | Medical sciences | Tumors | Kidney Neoplasms - genetics | Carcinoma, Renal Cell - pathology | Proto-Oncogene Proteins c-met - antagonists & inhibitors | Anilides - adverse effects | Humans | Middle Aged | Carcinoma, Renal Cell - genetics | Male | Protein Kinase Inhibitors - adverse effects | Quinolines - administration & dosage | Proto-Oncogene Proteins c-met - genetics | Disease-Free Survival | Protein Kinase Inhibitors - administration & dosage | Vascular Endothelial Growth Factor Receptor-2 - antagonists & inhibitors | Anilides - administration & dosage | Germ-Line Mutation | Female | Kidney Neoplasms - pathology | Biomarkers, Tumor - genetics | Retrospective Studies | Carcinoma, Renal Cell - drug therapy | Kidney Neoplasms - drug therapy | Quinolines - adverse effects | Cohort Studies | Index Medicus | ORIGINAL REPORTS
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5. Full Text Molecular genetics and cellular features of TFE3 and TFEB fusion kidney cancers
by Kauffman, Eric C and Ricketts, Christopher J and Rais-Bahrami, Soroush and Yang, Youfeng and Merino, Maria J and Bottaro, Donald P and Srinivasan, Ramaprasad and Linehan, W. Marston
Nature reviews. Urology, ISSN 1759-4812, 2014, Volume 11, Issue 8, pp. 465 - 475
Life Sciences & Biomedicine | Urology & Nephrology | Science & Technology | Kidney Neoplasms - genetics | Humans | Carcinogenesis - genetics | Gene Expression Regulation, Neoplastic | Carcinoma, Renal Cell - genetics | Molecular Sequence Data | Gene Fusion | Kidney Neoplasms - metabolism | Carcinogenesis - metabolism | Carcinoma, Renal Cell - metabolism | Base Sequence | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - genetics | Biomarkers, Tumor - metabolism | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - metabolism | Biomarkers, Tumor - genetics | Care and treatment | Oncology, Experimental | Genetic research | Development and progression | Genetic aspects | Carcinoma, Renal cell | Research | Gene fusion | Cancer | Index Medicus
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6. Full Text Defining Early-Onset Kidney Cancer: Implications for Germline and Somatic Mutation Testing and Clinical Management
by Brian Shuch and Srinivas Vourganti and Christopher J. Ricketts and Lindsay Middleton and James Peterson and Maria J. Merino and Adam R. Metwalli and Ramaprasad Srinivasan and W. Marston Linehan
Journal of clinical oncology, ISSN 0732-183X, 02/2014, Volume 32, Issue 5, pp. 431 - 437
Life Sciences & Biomedicine | Oncology | Science & Technology | Tumors of the urinary system | Kidneys | Nephrology. Urinary tract diseases | Biological and medical sciences | Multiple tumors. Solid tumors. Tumors in childhood (general aspects) | Medical sciences | Tumors | Predictive Value of Tests | United States - epidemiology | Kidney Neoplasms - genetics | Kidney Neoplasms - epidemiology | Prognosis | Humans | Middle Aged | Carcinoma, Renal Cell - genetics | Male | Genetic Testing - methods | Incidence | Kidney Neoplasms - diagnosis | Patient Selection | Young Adult | DNA Mutational Analysis | Aged, 80 and over | Germ-Line Mutation | Adult | Female | Child | Kidney Neoplasms - therapy | Precision Medicine | Genetic Predisposition to Disease | SEER Program | Risk Factors | Heredity | Carcinoma, Renal Cell - epidemiology | Phenotype | Pedigree | Carcinoma, Renal Cell - diagnosis | Adolescent | Age of Onset | Carcinoma, Renal Cell - therapy | Aged | Models, Genetic | Index Medicus | Pedi21 | ORIGINAL REPORTS
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7. Full Text New strategies in renal cell carcinoma: Targeting the genetic and metabolic basis of disease
by Srinivasan, Ramaprasad and Ricketts, Christopher J and Sourbier, Carole and Linehan, W. Marston
Clinical cancer research, ISSN 1078-0432, 01/2015, Volume 21, Issue 1, pp. 10 - 17
Life Sciences & Biomedicine | Oncology | Science & Technology | Metabolic Networks and Pathways - genetics | Carcinoma, Renal Cell - pathology | Humans | NF-E2-Related Factor 2 - metabolism | Carcinoma, Renal Cell - genetics | Chromatin Assembly and Disassembly - genetics | NF-E2-Related Factor 2 - genetics | Mutation | Carcinoma, Renal Cell - drug therapy | Molecular Targeted Therapy | Genetic Heterogeneity | Precision Medicine | Index Medicus
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8. Full Text Aerobic glycolysis: a novel target in kidney cancer
by Shuch, Brian and Linehan, W Marston and Srinivasan, Ramaprasad
Expert review of anticancer therapy, ISSN 1473-7140, 06/2013, Volume 13, Issue 6, pp. 711 - 719
kidney cancer | metabolism | Krebs cycle | glycolysis | Warburg effect | Life Sciences & Biomedicine | Oncology | Science & Technology | Kidney Neoplasms - genetics | Pyruvate Kinase - metabolism | Carcinoma, Renal Cell - pathology | Humans | Leiomyomatosis - metabolism | Angiogenesis Inhibitors - pharmacology | Carcinoma, Renal Cell - genetics | Kidney Neoplasms - metabolism | Glycolysis - genetics | Carcinoma, Renal Cell - metabolism | Citric Acid Cycle - genetics | Succinate Dehydrogenase - genetics | Animals | Carcinoma, Renal Cell - therapy | Glucose - metabolism | Kidney Neoplasms - pathology | Succinate Dehydrogenase - metabolism | Hexokinase - metabolism | Leiomyomatosis - genetics | Kidney Neoplasms - therapy | Molecular Targeted Therapy - methods | Glycolysis | Physiological aspects | Care and treatment | Genetic aspects | Research | Kidney cancer
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9. Full Text Coupled field formulation of exactly integrated membrane finite elements insensitive to distortion
by Srinivasan, Ramaprasad and Dattaguru, B and Singh, Gajbir
International journal of computational methods in engineering science and mechanics, ISSN 1550-2287, 11/2020, Volume 22, Issue 1, pp. 60 - 80
Kinematic coupling | compatibility conditions | inf-sup test | strong patch test | natural boundary conditions | Flamant's problem | field equilibrium equations
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10. Full Text Molecular diagnosis and therapy of kidney cancer
by Linehan, W. Marston and Bratslavsky, Gennady and Pinto, Peter A and Schmidt, Laura S and Neckers, Len and Bottaro, Donald P and Srinivasan, Ramaprasad
Annual review of medicine, ISSN 0066-4219, 02/2010, Volume 61, Issue 1, pp. 329 - 343
TSC2 | TSC1 | VHL | Fumarate hydratase succinate dehydrogenase | MET | BHD | Kidney neoplasms | Kidney Neoplasms - genetics | Humans | Carcinoma - diagnosis | Proto-Oncogene Proteins - genetics | Antineoplastic Agents - therapeutic use | Kidney Neoplasms - diagnosis | Proto-Oncogene Proteins c-met - genetics | Receptors, Growth Factor - genetics | Tuberous Sclerosis Complex 2 Protein | Tumor Suppressor Proteins - genetics | Carcinoma - genetics | Carcinoma - therapy | Tuberous Sclerosis Complex 1 Protein | Von Hippel-Lindau Tumor Suppressor Protein - genetics | Kidney Neoplasms - therapy | Care and treatment | Genetic aspects | Research | Diagnosis | Molecular biology | Kidney cancer | Proteins | Genetics | Kidney diseases | Disease management | Medical diagnosis | Cancer therapies | Cells | Index Medicus | fumarate hydratase succinate dehydrogenase | kidney neoplasms
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11. Full Text Renal medullary carcinoma: Molecular, immunohistochemistry, and morphologic correlation
by Liu, Qingyan and Galli, Susanna and Srinivasan, Ramaprasad and Linehan, William Marston and Tsokos, Maria and Merino, Maria J
The American journal of surgical pathology, ISSN 0147-5185, 03/2013, Volume 37, Issue 3, pp. 368 - 374
renal medullary carcinoma | loss of heterozygosity | SMARCB1 | Pathology | Life Sciences & Biomedicine | Surgery | Science & Technology | Immunohistochemistry | Kidney Neoplasms - genetics | Biomarkers, Tumor - analysis | Carcinoma, Renal Cell - pathology | Humans | Carcinoma, Renal Cell - genetics | Male | Transcription Factors - biosynthesis | Kidney Neoplasms - metabolism | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Chromosomal Proteins, Non-Histone - genetics | Loss of Heterozygosity - genetics | Microsatellite Repeats - genetics | SMARCB1 Protein | Young Adult | Carcinoma, Renal Cell - metabolism | Adolescent | Chromosomal Proteins, Non-Histone - biosynthesis | Adult | Female | Kidney Neoplasms - pathology | Child | DNA-Binding Proteins - biosynthesis | Index Medicus
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12. Full Text Sarcomatoid Renal Cell Carcinoma: A Comprehensive Review of the Biology and Current Treatment Strategies
by Shuch, Brian and Bratslavsky, Gennady and Linehan, W. Marston and Srinivasan, Ramaprasad
The oncologist (Dayton, Ohio), ISSN 1083-7159, 01/2012, Volume 17, Issue 1, pp. 46 - 54
Renal cell carcinoma | Sarcomatoid | Kidney cancer | Life Sciences & Biomedicine | Oncology | Science & Technology | Carcinoma, Renal Cell - therapy | Kidney Neoplasms - pathology | Carcinoma, Renal Cell - pathology | Humans | Kidney Neoplasms - therapy | Index Medicus | Renal, Bladder, and Testicular | Genitourinary Cancer
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