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1. Full Text Phase II and Biomarker Study of the Dual MET/VEGFR2 Inhibitor Foretinib in Patients With Papillary Renal Cell Carcinoma
by Toni K. Choueiri and Ulka Vaishampayan and Jonathan E. Rosenberg and Theodore F. Logan and Andrea L. Harzstark and Ronald M. Bukowski and Brian I. Rini and Sandy Srinivas and Mark N. Stein and Laurel M. Adams and Lone H. Ottesen and Kevin H. Laubscher and Laurie Sherman and David F. McDermott and Naomi B. Haas and Keith T. Flaherty and Robert Ross and Peter Eisenberg and Paul S. Meltzer and Maria J. Merino and Donald P. Bottaro and W. Marston Linehan and Ramaprasad Srinivasan
Journal of Clinical Oncology, ISSN 0732-183X, 01/2013, Volume 31, Issue 2, pp. 181 - 186
Purpose Foretinib is an oral multikinase inhibitor targeting MET, VEGF, RON, AXL, and TIE-2 receptors. Activating mutations or amplifications in MET have been... 
MET PROTOONCOGENE | INTERFERON-ALPHA | EFFICACY | ONCOLOGY | C-MET | SUNITINIB | THERAPIES | MUTATIONS | SORAFENIB | CANCER | TUMORS | Kidney Neoplasms - genetics | Carcinoma, Renal Cell - pathology | Proto-Oncogene Proteins c-met - antagonists & inhibitors | Anilides - adverse effects | Humans | Middle Aged | Carcinoma, Renal Cell - genetics | Male | Protein Kinase Inhibitors - adverse effects | Quinolines - administration & dosage | Proto-Oncogene Proteins c-met - genetics | Disease-Free Survival | Protein Kinase Inhibitors - administration & dosage | Vascular Endothelial Growth Factor Receptor-2 - antagonists & inhibitors | Anilides - administration & dosage | Germ-Line Mutation | Female | Kidney Neoplasms - pathology | Biomarkers, Tumor - genetics | Retrospective Studies | Carcinoma, Renal Cell - drug therapy | Kidney Neoplasms - drug therapy | Quinolines - adverse effects | Cohort Studies | Index Medicus | ORIGINAL REPORTS
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2. Full Text Treating advanced kidney cancer—miles to go before we sleep
by Linehan, W. Marston and Srinivasan, Ramaprasad
Nature Reviews Clinical Oncology, ISSN 1759-4774, 11/2013, Volume 10, Issue 11, pp. 614 - 615
Linehan, W. M. & Srinivasan, R. Nat. Rev. Clin. Oncol. 10, 614-615 (2013); published online 15 October 2013; doi: 10.1038/nrclinonc.2013.183 
Treatment outcome | Care and treatment | Patient outcomes | Carcinoma, Renal cell | Research | Drug therapy | Comparative analysis | Pazopanib | Cancer
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3. Full Text Defining Early-Onset Kidney Cancer: Implications for Germline and Somatic Mutation Testing and Clinical Management
by Brian Shuch and Srinivas Vourganti and Christopher J. Ricketts and Lindsay Middleton and James Peterson and Maria J. Merino and Adam R. Metwalli and Ramaprasad Srinivasan and W. Marston Linehan
Journal of Clinical Oncology, ISSN 0732-183X, 02/2014, Volume 32, Issue 5, pp. 431 - 437
Purpose Approximately 5% to 8% of renal cell carcinoma (RCC) is hereditary. No guidelines exist for patient selection for RCC germline mutation testing. We... 
YOUNG-ADULTS | TRANSLOCATION | GENETIC-BASIS | ONCOLOGY | DISEASE | HOGG-DUBE-SYNDROME | HEREDITARY LEIOMYOMATOSIS | SPECTRUM | RENAL-CELL CARCINOMA | CHILDREN | Predictive Value of Tests | United States - epidemiology | Kidney Neoplasms - genetics | Kidney Neoplasms - epidemiology | Prognosis | Humans | Middle Aged | Carcinoma, Renal Cell - genetics | Male | Genetic Testing - methods | Incidence | Kidney Neoplasms - diagnosis | Patient Selection | Young Adult | DNA Mutational Analysis | Aged, 80 and over | Germ-Line Mutation | Adult | Female | Child | Kidney Neoplasms - therapy | Precision Medicine | Genetic Predisposition to Disease | SEER Program | Risk Factors | Heredity | Carcinoma, Renal Cell - epidemiology | Phenotype | Pedigree | Carcinoma, Renal Cell - diagnosis | Adolescent | Age of Onset | Carcinoma, Renal Cell - therapy | Aged | Models, Genetic | Index Medicus | Pedi21 | ORIGINAL REPORTS
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4. Full Text Exact solutions for laminated composite beams using a unified state space formulation
by Srinivasan, Ramaprasad and Dattaguru, B and Singh, Gajbir
International Journal for Computational Methods in Engineering Science and Mechanics, ISSN 1550-2287, 07/2019, Volume 20, Issue 4, pp. 319 - 334
The variationally consistent methodology for generating state space models of 1D composite beams is evolved systematically and used to establish such models... 
unsymmetric layup | exact solution | generalized forces | laminated composite beams | State space formulation | material coupling | essential and natural boundary conditions
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5. Full Text An open-label phase II study to evaluate PT2977 for the treatment of von Hippel-Lindau disease-associated renal cell carcinoma
by Jonasch, Eric and Park, Eric Kristopher and Thamake, Sanjay and Hirmand, Mohammad and Linehan, W. Marston and Srinivasan, Ramaprasad
Journal of Clinical Oncology, ISSN 0732-183X, 03/2019, Volume 37, Issue 7_suppl, pp. TPS680 - TPS680
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6. Full Text Abstract 3842: Potent antitumor activity of the HSP90 inhibitor SNX-2112 in type 1 papillary renal cell carcinoma
by Pahwa, Roma and Giri, Abhigya and Sourbier, Carole and Thomas, Craig and Linehan, W Marston and Neckers, Len and Srinivasan, Ramaprasad
Cancer Research, ISSN 0008-5472, 07/2018, Volume 78, Issue 13 Supplement, pp. 3842 - 3842
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7. Full Text Targeted therapies: Treating advanced kidney cancer - Miles to go before we sleep
by Linehan, W. Marston and Srinivasan, Ramaprasad
Nature Reviews Clinical Oncology, ISSN 1759-4774, 11/2013, Volume 10, Issue 11, pp. 614 - 615
A randomized phase III trial comparing pazopanib with sunitinib in patients with advanced clear cell renal cell carcinoma showed that although progression-free... 
ONCOLOGY | RENAL-CELL CARCINOMA | Prognosis | Sulfonamides - therapeutic use | Pyrimidines - therapeutic use | Carcinoma, Renal Cell - secondary | Humans | Angiogenesis Inhibitors - therapeutic use | Receptors, Vascular Endothelial Growth Factor - antagonists & inhibitors | Kidney Neoplasms - pathology | Clinical Trials as Topic | Carcinoma, Renal Cell - drug therapy | Kidney Neoplasms - drug therapy | Molecular Targeted Therapy | Index Medicus
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8. Full Text PD51-01 MANAGEMENT OF GENETICALLY DEFINED RENAL TUMORS UTILIZING SIZE-BASED RISK STRATIFICATION: LONG-TERM RESULTS
by Ball, Mark and An, Julie and Peteron, James and Merino, Maria and Srinivasan, Ramaprasad and Metwalli, Adam and Linehan, W. Marston
The Journal of Urology, ISSN 0022-5347, 04/2018, Volume 199, Issue 4, pp. e975 - e975
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9. Full Text New strategies in renal cell carcinoma: Targeting the genetic and metabolic basis of disease
by Srinivasan, Ramaprasad and Ricketts, Christopher J and Sourbier, Carole and Linehan, W. Marston
Clinical Cancer Research, ISSN 1078-0432, 01/2015, Volume 21, Issue 1, pp. 10 - 17
The development of new forms of treatment of advanced renal cell carcinoma over the past two decades has been primarily focused on targeting the VHL/HIF... 
HYPOXIA-INDUCIBLE FACTOR | FACTOR 1-ALPHA | GERMLINE | INHIBITION | ONCOLOGY | FUMARATE-HYDRATASE | HEREDITARY LEIOMYOMATOSIS | MUTATIONS | HIF-ALPHA | KIDNEY CANCER | REDUCTIVE CARBOXYLATION | Metabolic Networks and Pathways - genetics | Carcinoma, Renal Cell - pathology | Humans | NF-E2-Related Factor 2 - metabolism | Carcinoma, Renal Cell - genetics | Chromatin Assembly and Disassembly - genetics | NF-E2-Related Factor 2 - genetics | Mutation | Carcinoma, Renal Cell - drug therapy | Molecular Targeted Therapy | Genetic Heterogeneity | Precision Medicine | Index Medicus
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10. Full Text The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma
by Ricketts, Christopher J and De Cubas, Aguirre A and Fan, Cheng and Fan, Huihui and Smith, Christof C and Smith, Jennifer and Lang, James and Lang, Martin and Reznik, Ed and Bowlby, Reanne and Gibb, Ewan A and Akbani, Rehan and Beroukhim, Rameen and Bottaro, Donald P and Choueiri, Toni K and Gibbs, Richard A and Godwin, Andrew K and Godwin, Eryn M and Haake, Scott and Hakimi, A. Ari and Henske, Elizabeth P and Hsieh, James J and Ho, Thai and Ho, Thai H and Kanchi, Rupa S and Krishnan, Bhavani and Kwiatkowski, David J and Lui, Wembin and Merino, Maria J and Mills, Gordon B and Myers, Jerome and Nickerson, Michael L and Reuter, Victor E and Reuter, Victor and Schmidt, Laura S and Schmidt, Heather K and Shelley, C. Simon and Shelley, Carl Simon and Shen, Hui and Shuch, Brian and Signoretti, Sabina and Srinivasan, Ramaprasad and Tamboli, Pheroze and Thomas, George and Vincent, Benjamin G and Vocke, Cathy D and Wheeler, David A and Yang, Lixing and Yang, Ian and Yang, Ju Dong and Yang, Hannah and Yang, Liming and Kim, Jaegil and Kim, William Y and Robertson, A. Gordon and Caesar-Johnson, Samantha J and Demchok, John A and Felau, Ina and Kasapi, Melpomeni and Ferguson, Martin L and Hutter, Carolyn M and Sofia, Heidi J and Tarnuzzer, Roy and Wang, Timothy and Wang, Linghua and Wang, Jioajiao and Wang, Min and Wang, Zhining and Wang, Jing and Zenklusen, Jean C and Zhang, Hailei and Zhang, Jiashan (Julia) and Zhang, Wei and Zhang, Hongxin and Zhang, Lizhi and Zhang, Jiexin and Zhang, Hongzheng and Chudamani, Sudha and Liu, Wenbin and Liu, Jia and Liu, Yuexin and Liu, Xiuping and Lolla, Laxmi and Naresh, Rashi and Pihl, Todd and Sun, Qiang and Sun, Yichao and Wan, Yunhu and Wu, Ye and Cho, Juok and DeFreitas, Timothy and Frazer, Scott and Gehlenborg, Nils and Getz, Gad and Heiman, David I and Lawrence, Michael S and Lin, Pei and Meier, Sam and Noble, Michael S and Saksena, Gordon and ... and Canc Genome Atlas Res Network and Cancer Genome Atlas Research Network
Cell Reports, ISSN 2211-1247, 04/2018, Volume 23, Issue 1, pp. 313 - 326.e5
Renal cell carcinoma (RCC) is not a single disease, but several histologically defined cancers with different genetic drivers, clinical courses, and... 
clear cell renal cell carcinoma | papillary renal cell carcinoma | chromophobe renal cell carcinoma | CDKN2A | PanCanAtlas | immune signature | chromatin remodeling | DNA hypermethylation | TCGA | GENETIC-BASIS | MESSENGER-RNA | RNA-SEQ | DNA | SOMATIC POINT MUTATIONS | SEQUENCING DATA | CLASS DISCOVERY | EXPRESSION | KIDNEY CANCER | BREAST | CELL BIOLOGY | Index Medicus
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11. Full Text Regression of human kidney cancer following allogeneic stem cell transplantation is associated with recognition of an HERV-E antigen by T cells
by Takahashi, Yoshiyuki and Harashima, Nanae and Kajigaya, Sachiko and Yokoyama, Hisayuki and Cherkasova, Elena and McCoy, J. Philip and Hanada, Ken-Ichi and Mena, Othon and Kurlander, Roger and Abdul, Tawab and Srinivasan, Ramaprasad and Lundqvist, Andreas and Malinzak, Elizabeth and Geller, Nancy and Lerman, Michael I and Childs, Richard W
Journal of Clinical Investigation, ISSN 0021-9738, 2008, Volume 118, Issue 3, pp. 1099 - 1109
Transplanted donor lymphocytes infused during hematopoietic stem cell transplantation (HSCT) have been shown to cure patients with hematological malignancies.... 
MEDICINE, RESEARCH & EXPERIMENTAL | MELANOMA | CARCINOMA | EXPRESSION | HUMAN-ENDOGENOUS-RETROVIRUS | LYMPHOCYTES | Amino Acid Sequence | Humans | Middle Aged | Kidney Neoplasms - immunology | Hematopoietic Stem Cell Transplantation | Molecular Sequence Data | Male | Carcinoma, Renal Cell - immunology | T-Lymphocytes, Cytotoxic - physiology | Transplantation, Homologous | Antigens, Viral - immunology | Base Sequence | Carcinoma, Renal Cell - therapy | Cell Line, Tumor | Adult | Endogenous Retroviruses - immunology | T-Lymphocytes - immunology | Kidney Neoplasms - therapy | Complications and side effects | Care and treatment | Immunotherapy | Kidney cancer | Stem cells | Transplantation | Research | Diagnosis | Health aspects | Methods | Risk factors | Index Medicus | Abridged Index Medicus
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12. Full Text Comprehensive genomic and phenotypic characterization of germline FH deletion in hereditary leiomyomatosis and renal cell carcinoma
by Vocke, Cathy D and Ricketts, Christopher J and Merino, Maria J and Srinivasan, Ramaprasad and Metwalli, Adam R and Middelton, Lindsay A and Peterson, James and Yang, Youfeng and Linehan, W. Marston
Genes, Chromosomes and Cancer, ISSN 1045-2257, 06/2017, Volume 56, Issue 6, pp. 484 - 492
Hereditary leiomyomatosis and renal cell carcinoma (HLRCC) is a familial cancer syndrome associated with the development of cutaneous and uterine leiomyomas,... 
CANCER HLRCC | GENE | ONCOLOGY | FAMILIES | HIPPEL-LINDAU-DISEASE | GENETICS & HEREDITY | FUMARATE-HYDRATASE | MUTATIONS | SPECTRUM | UTERINE LEIOMYOMAS | NORTH-AMERICA | Kidney Neoplasms - genetics | Humans | Carcinoma, Renal Cell - genetics | In Situ Hybridization, Fluorescence | Male | Fumarate Hydratase - genetics | Phenotype | Pedigree | Gene Deletion | Germ-Line Mutation | Female | Genome | Leiomyomatosis - genetics | Cytogenetics | Genetic aspects | Carcinoma, Renal cell | Gene mutations | Analysis | Cancer | Kidney cancer | Mutation | Index Medicus
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13. Full Text Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma
by Linehan, W. Marston and Spellman, Paul T and Ricketts, Christopher J and Creighton, Chad J and Fei, Suzanne S and Davis, Caleb and Wheeler, David A and Murray, Bradley A and Schmidt, Laura and Vocke, Cathy D and Peto, Myron and Al Mamun, Abu Amar M and Shinbrot, Eve and Sethi, Anurag and Brooks, Samira and Rathmell, W. Kimryn and Brooks, Angela N and Hoadley, Katherine A and Robertson, A. Gordon and Brooks, Denise and Bowlby, Reanne and Sadeghi, Sara and Shen, Hui and Weisenberger, Daniel J and Bootwalla, Moiz and Baylin, Stephen B and Laird, Peter W and Cherniack, Andrew D and Saksena, Gordon and Haake, Scott and Li, Jun and Liang, Han and Lu, Yiling and Mills, Gordon B and Akbani, Rehan and Leiserson, Mark D.M and Raphael, Benjamin J and Anur, Pavana and Bottaro, Donald and Albiges, Laurence and Barnabas, Nandita and Choueiri, Toni K and Czerniak, Bogdan and Godwin, Andrew K and Hakimi, A. Ari and Ho, Thai H and Hsieh, James and Ittmann, Michael and Kim, William Y and Krishnan, Bhavani and Merino, Maria J and Shaw, Kenna R. Mills and Reuter, Victor E and Reznik, Ed and Shelley, Carl S and Shuch, Brian and Signoretti, Sabina and Srinivasan, Ramaprasad and Tamboli, Pheroze and Thomas, George and Tickoo, Satish and Burnett, Kenneth and Crain, Daniel and Gardner, Johanna and Lau, Kevin and Mallery, David and Morris, Scott and Paulauskis, Joseph D and Penny, Robert J and Shelton, Candace and Shelton, W. Troy and Sherman, Mark and Thompson, Eric and Yena, Peggy and Avedon, Melissa T and Bowen, Jay and Gastier-Foster, Julie M and Gerken, Mark and Leraas, Kristen M and Lichtenberg, Tara M and Ramirez, Nilsa C and Santos, Tracie and Wise, Lisa and Zmuda, Erik and Demchok, John A and Felau, Ina and Hutter, Carolyn M and Sheth, Margi and Sofia, Heidi J and Tarnuzzer, Roy and Wang, Zhining and Yang, Liming and Zenklusen, Jean C and Zhang, Jiashan and Ayala, Brenda and Baboud, Julien and Chudamani, Sudha and Liu, Jia and Lolla, Laxmi and Naresh, Rashi and ... and The Cancer Genome Atlas Research Network and Canc Genome Atlas Res Network and Cancer Genome Atlas Research Network
The New England Journal of Medicine, ISSN 0028-4793, 01/2016, Volume 374, Issue 2, pp. 135 - 145
Papillary renal-cell carcinomas account for 15 to 20% of kidney cancers. Type 1, which is often multifocal and more indolent, was associated with mutations in... 
FUMARATE | MEDICINE, GENERAL & INTERNAL | MET PROTOONCOGENE | GENETIC-BASIS | GERMLINE | HEREDITARY | NRF2 | PHENOTYPE | MUTATIONS | EXPRESSION | KIDNEY CANCER | Proto-Oncogene Proteins c-met - metabolism | RNA, Neoplasm - chemistry | Carcinoma, Papillary - genetics | Kidney Neoplasms - genetics | Humans | Kidney Neoplasms - metabolism | CpG Islands - physiology | Carcinoma, Papillary - metabolism | Proto-Oncogene Proteins c-met - genetics | DNA Methylation | Phenotype | Sequence Analysis, RNA | NF-E2-Related Factor 2 - metabolism | NF-E2-Related Factor 2 - genetics | RNA, Messenger - chemistry | Signal Transduction - physiology | Mutation | Proto-Oncogene Proteins c-met - chemistry | MicroRNAs - chemistry | Care and treatment | Histology | Carcinoma, Renal cell | Research | Gene mutations | Analysis | Phenotypes | Carcinoma | Cell survival | MiRNA | mRNA | Genomes | Antioxidants | Fumarate hydratase | Kidney cancer | DNA methylation | Molecular biology | Methylation | Chromosomes | Clear cell-type renal cell carcinoma | DNA sequencing | CpG islands | Tumors | Index Medicus | Abridged Index Medicus
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14. Full Text Editorial comment
by Singer, Eric A and Srinivasan, Ramaprasad and Bratslavsky, Gennady
Journal of Urology, ISSN 0022-5347, 01/2011, Volume 185, Issue 1, p. 66
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15. Full Text PD04-01 DETERMINANTS OF ALL-CAUSE MORTALITY IN PATIENTS WITH METASTATIC PAPILLARY RENAL CELL CANCER
by Sidana, Abhinav and Jain, Amit and Kadakia, Meet and Muthigi, Akhil and Krane, Louis and Ninos, Martha and Friend, Julia and Shih, Johanna and Srinivasan, Ramaprasad
Journal of Urology, The, ISSN 0022-5347, 2017, Volume 197, Issue 4, pp. e62 - e62
Urology | Patient outcomes | Mortality | Metastasis
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16. Full Text Challenging and refining treatment paradigms
by Ball, MW and Srinivasan, R
NATURE REVIEWS UROLOGY, ISSN 1759-4812, 02/2018, Volume 15, Issue 2, pp. 77 - U21
Treatment paradigms for advanced renal cell carcinoma (RCC) continue to be challenged and refined. Recent studies in metastatic RCC have demonstrated the... 
TRIAL | CABOZANTINIB | PLACEBO | THERAPY | EVEROLIMUS | HIGH-RISK | UROLOGY & NEPHROLOGY | RENAL-CELL CARCINOMA | NEPHRECTOMY | ADJUVANT SUNITINIB
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