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Critical Care, ISSN 1364-8535, 04/2017, Volume 21, Issue 1, pp. 89 - 89
Pharmacological and cellular treatment of cancer is changing dramatically with benefits for patient outcome and comfort, but also with new toxicity profiles.... 
Interdisciplinary management | Targeted therapy | Toxicity | Immunotherapy | Cancer | SAFETY | RISK | CHRONIC MYELOID-LEUKEMIA | TYROSINE KINASE INHIBITORS | THERAPY | BLINATUMOMAB | ARTERIAL OCCLUSIVE DISEASE | RECEPTOR T-CELLS | ADVERSE EVENTS | IPILIMUMAB | CRITICAL CARE MEDICINE | Immunotherapy - methods | Pyrazoles - therapeutic use | Drug-Related Side Effects and Adverse Reactions - complications | Humans | Antibodies, Monoclonal - adverse effects | Antibodies, Monoclonal - therapeutic use | Intensive Care Units - organization & administration | Immunotherapy - adverse effects | Neoplasms - drug therapy | Antibodies, Bispecific - therapeutic use | Antibodies, Bispecific - adverse effects | Pyrimidines - therapeutic use | Pyrimidines - adverse effects | Systemic Inflammatory Response Syndrome - etiology | Systemic Inflammatory Response Syndrome - complications | Drug-Related Side Effects and Adverse Reactions - physiopathology | Systemic Inflammatory Response Syndrome - drug therapy | Drug-Related Side Effects and Adverse Reactions - diagnosis | Cytokines - adverse effects | Pyrazoles - adverse effects | Cardiac arrhythmia | Disease | Leukemia | Colorectal cancer | Cytotoxicity | Kinases | Cancer therapies | Proteins | Neurotoxicity | Cell growth | Ischemia | Pharmaceutical industry | Vascular endothelial growth factor | Antigens | Immunoglobulins | Cytokines | Diarrhea | Breast cancer | Patients | Meta-analysis | Inflammatory bowel disease | Chemotherapy | Lymphomas | Tumors | Index Medicus
Journal Article
Journal Article
Nature Medicine, ISSN 1078-8956, 01/2017, Volume 23, Issue 1, pp. 69 - 78
In acute myeloid leukemia (AML), therapy resistance frequently occurs, leading to high mortality among patients. However, the mechanisms that render leukemic... 
TRANSFORMATION | MEDICINE, RESEARCH & EXPERIMENTAL | CELLS | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | CANCER | SOMATIC MUTATIONS | CELL BIOLOGY | THERAPY | GENE EZH2 | DIFFERENTIATION | INHIBITOR | EXPRESSION | Immunohistochemistry | CDC2 Protein Kinase | Enhancer of Zeste Homolog 2 Protein - antagonists & inhibitors | Neoplasm Transplantation | Cyclin-Dependent Kinases - metabolism | Cytarabine - pharmacology | Immunoprecipitation | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Male | Bortezomib - pharmacology | Gene Knockdown Techniques | Young Adult | Flow Cytometry | Mass Spectrometry | Aged, 80 and over | Leukemia, Myeloid, Acute - drug therapy | Adult | Female | Indoles - pharmacology | Antineoplastic Agents - pharmacology | Enhancer of Zeste Homolog 2 Protein - genetics | Enhancer of Zeste Homolog 2 Protein - metabolism | Blotting, Western | Homeodomain Proteins - genetics | Drug Resistance, Neoplasm - genetics | Protein Kinase Inhibitors | Animals | Proteomics | Cell Line, Tumor | HSP90 Heat-Shock Proteins - metabolism | Aged | Mice | Protein Processing, Post-Translational | Histones - metabolism | Proteasome Endopeptidase Complex - metabolism | Pyridones - pharmacology | Leukemia, Myeloid, Acute - genetics | Genetic aspects | Methyltransferases | Drug resistance | Health aspects | Antimitotic agents | Prognosis | Mortality | Heat shock proteins | Histones | Drug therapy | Antineoplastic agents | Gene expression | Drugs | Therapy | Hsp90 protein | Phosphorylation | Leukemia | Chemoresistance | Cytotoxicity | Kinases | Degradation | Proteins | Cytarabine | Restoration | Histone methyltransferase | HOX gene | Protein-tyrosine kinase | Tyrosine | Bortezomib | Myeloid leukemia | Patients | Sensitivity | Inhibitors | Derepression | Cell lines | Proteasomes | Blast resistance | Methylation | Acute myeloid leukemia | Heat shock
Journal Article
by Mathew, Nimitha R and Baumgartner, Francis and Braun, Lukas and O'Sullivan, David and Thomas, Simone and Waterhouse, Miguel and Müller, Tony A and Hanke, Kathrin and Taromi, Sanaz and Apostolova, Petya and Illert, Anna L and Melchinger, Wolfgang and Duquesne, Sandra and Schmitt-Graeff, Annette and Osswald, Lena and Yan, Kai-Li and Weber, Arnim and Tugues, Sonia and Spath, Sabine and Pfeifer, Dietmar and Follo, Marie and Claus, Rainer and Lübbert, Michael and Rummelt, Christoph and Bertz, Hartmut and Wäsch, Ralph and Haag, Johanna and Schmidts, Andrea and Schultheiss, Michael and Bettinger, Dominik and Thimme, Robert and Ullrich, Evelyn and Tanriver, Yakup and Vuong, Giang Lam and Arnold, Renate and Hemmati, Philipp and Wolf, Dominik and Ditschkowski, Markus and Jilg, Cordula and Wilhelm, Konrad and Leiber, Christian and Gerull, Sabine and Halter, Jörg and Lengerke, Claudia and Pabst, Thomas and Schroeder, Thomas and Kobbe, Guido and Rösler, Wolf and Doostkam, Soroush and Meckel, Stephan and Stabla, Kathleen and Metzelder, Stephan K and Halbach, Sebastian and Brummer, Tilman and Hu, Zehan and Dengjel, Joern and Hackanson, Björn and Schmid, Christoph and Holtick, Udo and Scheid, Christof and Spyridonidis, Alexandros and Stölzel, Friedrich and Ordemann, Rainer and Müller, Lutz P and Sicre-De-Fontbrune, Flore and Ihorst, Gabriele and Kuball, Jürgen and Ehlert, Jan E and Feger, Daniel and Wagner, Eva-Maria and Cahn, Jean-Yves and Schnell, Jacqueline and Kuchenbauer, Florian and Bunjes, Donald and Chakraverty, Ronjon and Richardson, Simon and Gill, Saar and Kröger, Nicolaus and Ayuk, Francis and Vago, Luca and Ciceri, Fabio and Müller, Antonia M and Kondo, Takeshi and Teshima, Takanori and Klaeger, Susan and Kuster, Bernhard and Kim, Dennis H and Weisdorf, Daniel and Van Der Velden, Walter and Dörfel, Daniela and Bethge, Wolfgang and Hilgendorf, Inken and Hochhaus, Andreas and Andrieux, Geoffroy and Börries, Melanie and Busch, Hauke and Magenau, John and Reddy, Pavan and Labopin, Myriam and Antin, Joseph H and ...
Nature Medicine, ISSN 1078-8956, 03/2018, Volume 24, Issue 3, pp. 282 - 291
Journal Article
The Lancet Oncology, ISSN 1470-2045, 12/2018, Volume 19, Issue 12, pp. 1668 - 1679
Journal Article
Haematologica, ISSN 0390-6078, 10/2011, Volume 96, Issue 10, pp. 1552 - 1556
Myeloid sarcoma in acute myeloid leukemia has been clearly defined by the World Health Organization but studies regarding the prevalence and the prognostic... 
Myeloid sarcoma | 18F-FDG-PET/CT | Extramedullary AML | Acute myeloid leukemia (AML) | extramedullary AML | acute myeloid leukemia (AML) | Brief Reports | 18F-FDG-PET | myeloid sarcoma
Journal Article
Journal Article