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Journal Article
Immunity, ISSN 1074-7613, 07/2012, Volume 37, Issue 1, pp. 171 - 186
Journal Article
Journal Article
Nature Communications, ISSN 2041-1723, 02/2017, Volume 8, Issue 1
Small-molecule inhibitor of apoptosis (IAP) antagonists, called Smac mimetic compounds (SMCs), sensitize tumours to TNF-alpha-induced killing while... 
ACTIVATION | VIRUS | INDUCED APOPTOSIS | INDUCE | IMMUNOTHERAPY | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | NF-KAPPA-B | CANCER | CIAP1 | CELL-DEATH | Interferon-alpha - pharmacology | Interferon-beta - immunology | Inhibitor of Apoptosis Proteins - genetics | Antineoplastic Agents - chemical synthesis | Humans | Tumor Necrosis Factor-alpha - genetics | Vesiculovirus - immunology | T-Lymphocytes, Cytotoxic - drug effects | Brain Neoplasms - immunology | Glioblastoma - genetics | Interferon-alpha - genetics | Tumor Necrosis Factor-alpha - immunology | Interferon-beta - genetics | Vesiculovirus - genetics | Female | Antineoplastic Agents - pharmacology | Brain Neoplasms - mortality | T-Lymphocytes, Cytotoxic - immunology | Poly I-C - pharmacology | Genetic Vectors - chemistry | Genetic Vectors - immunology | Immunity, Innate - drug effects | Signal Transduction | Gene Expression Regulation | Brain Neoplasms - genetics | Brain Neoplasms - drug therapy | B7-H1 Antigen - genetics | B7-H1 Antigen - immunology | Interferon-alpha - immunology | Xenograft Model Antitumor Assays | Tumor Necrosis Factor-alpha - pharmacology | Adaptive Immunity - drug effects | Animals | Glioblastoma - immunology | Interferon-beta - pharmacology | Thiazoles - chemical synthesis | Survival Analysis | Cell Line, Tumor | Immunologic Memory | Inhibitor of Apoptosis Proteins - immunology | Mice | Thiazoles - pharmacology | Glioblastoma - drug therapy | Glioblastoma - mortality | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2011, Volume 108, Issue 19, pp. 7944 - 7949
Type I and type III IFNs bind to different cell-surface receptors but induce identical signal transduction pathways, leading to the expression of antiviral... 
Antigens | Receptors | Rotavirus | Epithelial cells | Interferons | Rotavirus infections | Antivirals | Viruses | Mice | Infections | Biological Sciences
Journal Article
Nature Reviews Immunology, ISSN 1474-1733, 2019
Type III interferon (IFN-λ) was initially thought to have functions similar to those of the type I interferons (IFN-α and IFN-β). New findings have indicated,... 
Journal Article
PLoS Pathogens, ISSN 1553-7366, 11/2013, Volume 9, Issue 11, pp. e1003773 - e1003773
Interferons (IFNs) are a group of cytokines with a well-established antiviral function. They can be induced by viral infection, are secreted and bind to... 
CELLS | DEFENSE | VIRUS-INFECTION | DISTINCT | RIG-I | MICROBIOLOGY | IRF-7 | ANTIVIRAL RESPONSE | VIROLOGY | GENE | SIGNALING PATHWAY | ADAPTER PROTEIN | PARASITOLOGY | Epithelial Cells - metabolism | Influenza A virus - genetics | Respiratory Mucosa - virology | Interferon Regulatory Factor-7 - genetics | Interferon Type I - immunology | Interferon Regulatory Factor-3 - genetics | Interleukins - metabolism | Orthomyxoviridae Infections - genetics | Respiratory Mucosa - pathology | Interleukins - genetics | Interleukins - immunology | Respiratory Mucosa - immunology | Adaptor Proteins, Signal Transducing - immunology | Interferon Type I - metabolism | Influenza A virus - immunology | Membrane Proteins - metabolism | Interferon Regulatory Factor-3 - immunology | Nerve Tissue Proteins - immunology | Membrane Proteins - genetics | Orthomyxoviridae Infections - metabolism | Epithelial Cells - pathology | Membrane Proteins - immunology | Interferon Regulatory Factor-7 - immunology | Interferon Regulatory Factor-7 - metabolism | Nerve Tissue Proteins - genetics | Mice, Knockout | Nerve Tissue Proteins - metabolism | Animals | Influenza A virus - metabolism | Epithelial Cells - immunology | Epithelial Cells - virology | Adaptor Proteins, Signal Transducing - genetics | Interferon Regulatory Factor-3 - metabolism | Interferon Type I - genetics | Mice | Respiratory Mucosa - metabolism | Adaptor Proteins, Signal Transducing - metabolism | Orthomyxoviridae Infections - immunology | Epithelial cells | Influenza | Physiological aspects | Host-parasite relationships | Interferon | Genetic aspects | Genetic transcription | Research | Health aspects | Airway (Medicine) | Index Medicus | Interleukins/metabolism | Nerve Tissue Proteins/immunology | Orthomyxoviridae Infections/genetics | Orthomyxoviridae Infections/metabolism | Membrane Proteins/genetics | Adaptor Proteins, Signal Transducing/genetics | Interferon Regulatory Factor-7/genetics | Interleukins/immunology | Membrane Proteins/immunology | Life Sciences | Orthomyxoviridae Infections/immunology | Influenza A virus/genetics | Nerve Tissue Proteins/metabolism | Respiratory Mucosa/immunology | Immunology | Interferon Type I/immunology | Epithelial Cells/immunology | Epithelial Cells/virology | Interferon Regulatory Factor-7/immunology | Epithelial Cells/metabolism | Interferon Regulatory Factor-3/immunology | Respiratory Mucosa/pathology | Influenza A virus/immunology | Interleukins/genetics | Interferon Regulatory Factor-3/genetics | Influenza A virus/metabolism | Adaptor Proteins, Signal Transducing/metabolism | Epithelial Cells/pathology | Adaptor Proteins, Signal Transducing/immunology | Interferon Type I/genetics | Interferon Regulatory Factor-3/metabolism | Membrane Proteins/metabolism | Nerve Tissue Proteins/genetics | Interferon Regulatory Factor-7/metabolism | Interferon Type I/metabolism | Respiratory Mucosa/metabolism | Respiratory Mucosa/virology | Cytokines | Genes | Rodents | Genomics | Genomes | Kinases | Experiments | Viral infections
Journal Article