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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2008, Volume 105, Issue 20, pp. 7327 - 7332
Although deficiencies in the retromer sorting pathway have been linked to late-onset Alzheimer's disease, whether these deficiencies underlie the disease... 
Receptors | Animal models | Nervous system diseases | Disease models | Neurodegenerative diseases | Humans | Antibodies | Mice | Amyloids | Alzheimers disease | Pathophysiology | Flies | flies | INHIBITION | TRANSGENIC MODELS | MULTIDISCIPLINARY SCIENCES | pathophysiology | IN-VIVO | PLAQUE-FORMATION | AMYLOID PRECURSOR PROTEIN | mice | EXPRESSION | RECEPTOR LR11 | Biological Sciences
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 12/2008, Volume 28, Issue 53, pp. 14537 - 14545
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2014, Volume 9, Issue 3, p. e91954
Dynamin 1-3 isoforms are known to be involved in endocytotic processes occurring during synaptic transmission. No data has directly linked dynamins yet with... 
TRANSMITTER RELEASE | RELEASE PROBABILITY | ISOFORMS | INHIBITION | AMYLOID-BETA | CALMODULIN | MULTIDISCIPLINARY SCIENCES | LONG-TERM POTENTIATION | ENDOCYTOSIS | SYNAPTIC PLASTICITY | MODULATION | Memory - drug effects | Memory Disorders - physiopathology | RNA, Small Interfering - genetics | Electric Stimulation | Refractory Period, Electrophysiological - physiology | Synaptic Transmission - physiology | Memory Disorders - metabolism | Neuronal Plasticity - drug effects | Male | Hippocampus - drug effects | Dynamin I - genetics | Excitatory Postsynaptic Potentials - drug effects | Excitatory Postsynaptic Potentials - physiology | Neuronal Plasticity - physiology | Long-Term Potentiation - drug effects | Long-Term Potentiation - physiology | Synaptic Transmission - drug effects | Refractory Period, Electrophysiological - drug effects | Synapses - drug effects | Gene Expression | Synapses - physiology | Mice, Inbred C57BL | Hydrazones - pharmacology | Animals | Dynamin I - metabolism | Mice | Hippocampus - physiology | Dynamin I - antagonists & inhibitors | Memory - physiology | Memory Disorders - chemically induced | RNA, Small Interfering - metabolism | Animal behavior | Hostages | Memory | Potentiation | Long-term potentiation | Fatigue | Stimulation | Pharmacology | siRNA | Proteins | Associative memory | Brain research | Plasticity (synaptic) | Synaptic transmission | Isoforms | Dynamin | Aging | Inhibition | Laboratory animals | Alzheimers disease | Hippocampus
Journal Article
AIP Conference Proceedings, ISSN 0094-243X, 07/2017, Volume 1863, Issue 1
Medical centres are obliged to store past medical records, including the results of quality assurance (QA) tests of the medical equipment, which is especially... 
magnetic resonance spectroscopy | time series | change point detection | quality control | reproducibility | Medical equipment | Medical centres | Medical devices | Quality assurance | Nuclear magnetic resonance--NMR | Reproducibility | Quality control | Medical electronics | Singular value decomposition
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2013, Volume 8, Issue 6, p. e66226
Serine-threonine protein kinases are critical to CNS function, yet there is a dearth of highly selective, CNS-active kinase inhibitors for in vivo... 
POTENT | ACTIVATION | ALZHEIMERS-DISEASE | MULTIDISCIPLINARY SCIENCES | BEHAVIORAL DEFICITS | MOUSE MODEL | P38-ALPHA MAPK | CYTOKINE UP-REGULATION | INHIBITORS | BINDING | DISCOVERY | Mitogen-Activated Protein Kinase 14 - antagonists & inhibitors | Peptide Fragments - toxicity | Pyridines - chemistry | Humans | Brain - enzymology | Male | Pyridazines - pharmacology | Pyridazines - chemical synthesis | Brain - metabolism | Protein Kinase Inhibitors - chemistry | Long-Term Potentiation - drug effects | Drug Design | Mitogen-Activated Protein Kinase 14 - chemistry | Cell Line | Protein Kinase Inhibitors - chemical synthesis | Catalytic Domain | Amyloid beta-Peptides - toxicity | Mice, Inbred C57BL | Pyridines - chemical synthesis | Models, Molecular | Pyridazines - chemistry | Brain - drug effects | Animals | Protein Kinase Inhibitors - pharmacology | Pyridines - pharmacology | Development and progression | Nervous system diseases | Cognition disorders | Protein kinases | Analysis | G protein-coupled receptors | Target recognition | Disease | Serine | Central nervous system | Cognitive ability | Activation | Biology | Selectivity | Catalytic activity | Kinases | Crystallography | Neuronal-glial interactions | Proteins | Cascades | Modulation | Aging | Catalysis | Probes | Alzheimer's disease | Cytokines | Threonine | Neurodegenerative diseases | Pharmacology | Mammals | Screens | Studies | Pathology | Signaling | Chemistry | Inhibitors | Protein kinase | β-Amyloid | In vivo methods and tests
Journal Article
Journal Article
European Polymer Journal, ISSN 0014-3057, 10/2018, Volume 107, pp. 189 - 201
Nanocomposites based on poly(ethylene terephthalate-ethylene dilinoleate) (PET-DLA) copolymers of different hard to soft segment ratios (40:60 and 60:40) and... 
Carbon nanotubes | Thermoplastic elastomers | Carbon black | Heart assist device | Nanocomposites | Graphene | POLYMER SCIENCE | POLY(ETHYLENE-TEREPHTHALATE) | Biological products | Analysis | Graphite | Elastomers | Nanotubes | Mechanical properties | Polymerization | Nuclear magnetic resonance spectroscopy
Journal Article
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 06/2009, Volume 29, Issue 25, pp. 8075 - 8086
Memory loss, synaptic dysfunction, and accumulation of amyloid beta-peptides (A beta) are major hallmarks of Alzheimer's disease (AD). Downregulation of the... 
NEURONAL GENES | SILDENAFIL | AVOIDANCE | SELECTIVE PDE5 INHIBITOR | NITRIC-OXIDE | CGMP | RAT HIPPOCAMPUS | MICE | MECHANISMS | DYSFUNCTION | NEUROSCIENCES | Immunohistochemistry | Memory - drug effects | Piperazines - administration & dosage | Phosphodiesterase 5 Inhibitors | Purines - administration & dosage | Sulfones - pharmacology | Sildenafil Citrate | Time Factors | Amyloid beta-Peptides - metabolism | Polymerase Chain Reaction | Spatial Behavior - drug effects | Synaptic Transmission - drug effects | Phosphorylation - drug effects | Piperazines - pharmacokinetics | Alzheimer Disease - psychology | Disease Models, Animal | Psychomotor Performance | Conditioning, Classical - drug effects | Phosphodiesterase Inhibitors - pharmacokinetics | Purines - pharmacology | Purines - pharmacokinetics | Injections, Intraperitoneal | Alzheimer Disease - drug therapy | Phosphodiesterase Inhibitors - pharmacology | Mice, Transgenic | Treatment Outcome | Sulfones - pharmacokinetics | Piperazines - pharmacology | Neuropsychological Tests | Phosphodiesterase Inhibitors - administration & dosage | Amyloid beta-Protein Precursor - genetics | Animals | Analysis of Variance | Cyclic GMP - metabolism | Alzheimer Disease - metabolism | Cyclic AMP Response Element-Binding Protein - metabolism | Mice | Mutation | Sulfones - administration & dosage
Journal Article