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Movement Disorders, ISSN 0885-3185, 01/2013, Volume 28, Issue 1, p. 51
  The defining anatomical feature of Parkinson's disease (PD) is the degeneration of substantia nigra pars compacta (SNc) neurons, resulting in striatal... 
Journal Article
Acta Neuropathologica, ISSN 0001-6322, 10/2014, Volume 128, Issue 4, pp. 505 - 524
The occurrence of repeat-associated non-ATG (RAN) translation, an atypical form of translation of expanded repeats that results in the synthesis of... 
Pathology | Neurosciences | Medicine & Public Health | Expanded repeat | Repeat-associated non-ATG translation | ER stress | Amyotrophic lateral sclerosis | Frontotemporal dementia | C9ORF72 | Poly(GA) proteins | Proteasome activity | UBIQUITIN-PROTEASOME SYSTEM | CHEMICAL CHAPERONES | COGNITIVE IMPAIRMENT | ENDOPLASMIC-RETICULUM STRESS | AMYOTROPHIC-LATERAL-SCLEROSIS | PATHOLOGY | NEUROSCIENCES | NEURODEGENERATIVE DISEASES | CLINICAL NEUROLOGY | CELL-DEATH | C9ORF72 HEXANUCLEOTIDE REPEAT | RNA FOCI | Cholagogues and Choleretics - pharmacology | DNA Repeat Expansion - genetics | Embryo, Mammalian | Humans | Middle Aged | Male | DNA Repeat Expansion - immunology | Endoplasmic Reticulum Stress - genetics | Brain - metabolism | Frontotemporal Dementia - metabolism | Cell Nucleolus - metabolism | Cell Nucleolus - ultrastructure | Brain - ultrastructure | HEK293 Cells | Aged, 80 and over | Adult | Female | C9orf72 Protein | Frontotemporal Dementia - pathology | Frontotemporal Dementia - genetics | Endoplasmic Reticulum Stress - drug effects | Protein Structure, Secondary | Amyotrophic Lateral Sclerosis - genetics | Cells, Cultured | Antibodies - pharmacology | Gene Expression Regulation - drug effects | Nerve Tissue Proteins - metabolism | Amyotrophic Lateral Sclerosis - pathology | Animals | Proteins - metabolism | Amyotrophic Lateral Sclerosis - metabolism | Brain - pathology | Gene Expression Regulation - radiation effects | Aged | Mice | Proteins - chemistry | Endoplasmic Reticulum Stress - physiology | Proteins | Health aspects | Dementia | Index Medicus | Original Paper
Journal Article
Nature Neuroscience, ISSN 1097-6256, 05/2016, Volume 19, Issue 5, pp. 668 - 677
Journal Article
Alzheimer's Research and Therapy, ISSN 1758-9193, 05/2014, Volume 6, Issue 3, pp. 29 - 29
The identification of tau protein as a major constituent of neurofibrillary tangles spurred considerable effort devoted to identifying and validating pathways... 
DENDRITIC SPINES | PROTEIN-TAU | ALZHEIMERS-DISEASE | NONENZYMATIC ACETYLATION | PHF-TAU | MOUSE MODEL | LYSINE ACETYLATION | NEUROSCIENCES | CLINICAL NEUROLOGY | MICROTUBULE-STABILIZING AGENT | COGNITIVE DEFICITS | TRANSGENIC MICE | Alzheimer's disease | Tau proteins | Acetylation | Amino acids | Health aspects | Chronic brain injury
Journal Article
EMBO reports, ISSN 1469-221X, 09/2015, Volume 16, Issue 9, pp. 1114 - 1130
Journal Article
Journal Article
Molecular neurodegeneration, ISSN 1750-1326, 02/2019, Volume 14, Issue 1, pp. 9 - 9
Journal Article
by Gendron, Tania F and Chew, Jeannie and Stankowski, Jeannette N and Hayes, Lindsey R and Zhang, Yong-Jie and Prudencio, Mercedes and Carlomagno, Yari and Daughrity, Lillian M and Jansen-West, Karen and Perkerson, Emilie A and O'Raw, Aliesha and Cook, Casey and Pregent, Luc and Belzil, Veronique and Van Blitterswijk, Marka and Tabassian, Lilia J and Lee, Chris W and Yue, Mei and Tong, Jimei and Song, Yuping and Castanedes-Casey, Monica and Rousseau, Linda and Phillips, Virginia and Dickson, Dennis W and Rademakers, Rosa and Fryer, John D and Rush, Beth K and Pedraza, Otto and Caputo, Ana M and Desaro, Pamela and Palmucci, Carla and Robertson, Amelia and Heckman, Michael G and Diehl, Nancy N and Wiggs, Edythe and Tierney, Michael and Braun, Laura and Farren, Jennifer and Lacomis, David and Ladha, Shafeeq and Fournier, Christina N and McCluskey, Leo F and Elman, Lauren B and Toledo, Jon B and McBride, Jennifer D and Tiloca, Cinzia and Morelli, Claudia and Poletti, Barbara and Solca, Federica and Prelle, Alessandro and Wuu, Joanne and Jockel-Balsarotti, Jennifer and Rigo, Frank and Ambrose, Christine and Datta, Abhishek and Yang, Weixing and Raitcheva, Denitza and Antognetti, Giovanna and McCampbell, Alexander and Van Swieten, John C and Miller, Bruce L and Boxer, Adam L and Brown, Robert H and Bowser, Robert and Miller, Timothy M and Trojanowski, John Q and Grossman, Murray and Berry, James D and Hu, William T and Ratti, Antonia and Traynor, Bryan J and Disney, Matthew D and Benatar, Michael and Silani, Vincenzo and Glass, Jonathan D and Floeter, Mary Kay and Rothstein, Jeffrey D and Boylan, Kevin B and Petrucelli, Leonard
Science Translational Medicine, ISSN 1946-6234, 03/2017, Volume 9, Issue 383, pp. eaai7866 - eaai7866
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 07/2009, Volume 110, Issue 1, pp. 378 - 389
Manganese is an essential nutrient, integral to proper metabolism of amino acids, proteins and lipids. Excessive environmental exposure to manganese can... 
Striatum | Neurotoxicity | Dopamine | Parkinson's disease | Substantia nigra | Manganese | substantia nigra | OXIDATIVE-STRESS | BIOCHEMISTRY & MOLECULAR BIOLOGY | NEURODEGENERATION | ALPHA-SYNUCLEIN | manganese | BLOOD-BRAIN-BARRIER | INHALATION EXPOSURE | NEUROSCIENCES | TOTAL PARENTERAL-NUTRITION | IN-VITRO | neurotoxicity | striatum | RAT-BRAIN | ENERGY-METABOLISM | dopamine | Substantia Nigra - physiopathology | Tyrosine 3-Monooxygenase - metabolism | Synaptic Transmission - physiology | gamma-Aminobutyric Acid - metabolism | Basal Ganglia - metabolism | Endoplasmic Reticulum - metabolism | Substantia Nigra - metabolism | Endoplasmic Reticulum - pathology | Endoplasmic Reticulum - drug effects | Synaptic Transmission - drug effects | Neurons - metabolism | Neurons - drug effects | Dopamine - metabolism | Manganese Poisoning - physiopathology | Cytoskeleton - pathology | Basal Ganglia - physiopathology | Manganese - toxicity | Rats | Neurotoxins - toxicity | Magnesium Chloride - toxicity | Glutamate Decarboxylase - drug effects | Tyrosine 3-Monooxygenase - genetics | Substantia Nigra - drug effects | Animals | Cytoskeleton - metabolism | Glutamate Decarboxylase - metabolism | Mice | Cytoskeleton - drug effects | Basal Ganglia - drug effects | Manganese Poisoning - metabolism | Tyrosine | Neurosciences | Neurons | Fluorescence | Lipids | Glutamate | Risk factors | Proteins | Analysis | Physiological aspects | GABA | Hydroxylases | Manganese compounds | Neurology | Cell culture | Biochemistry | Cellular biology | Index Medicus | Parkinson’s disease
Journal Article
Journal Article