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Leukemia, ISSN 0887-6924, 02/2018, Volume 32, Issue 2, pp. 273 - 284
Journal Article
Leukemia, ISSN 0887-6924, 11/2013, Volume 27, Issue 11, pp. 2165 - 2176
Journal Article
Leukemia, ISSN 0887-6924, 03/2017, Volume 31, Issue 3, pp. 573 - 579
Journal Article
NATURE GENETICS, ISSN 1061-4036, 09/2015, Volume 47, Issue 9, pp. 1020 - 1020
TCF3-HLF-positive acute lymphoblastic leukemia (ALL) is currently incurable. Using an integrated approach, we uncovered distinct mutation, gene expression and... 
PROGENITOR CELLS | CHROMOSOMAL TRANSLOCATIONS | SET ENRICHMENT ANALYSIS | RAS PATHWAY | GENETICS & HEREDITY | GENE-EXPRESSION | B-CELL DIFFERENTIATION | SEQUENCING DATA | CHAIN REARRANGEMENT | TRANSCRIPTION FACTOR | HEMATOPOIETIC STEM | Sequence Deletion | Oncogene Proteins, Fusion - metabolism | Coculture Techniques | Genomics | Humans | Drug Resistance, Neoplasm | Male | Precursor Cell Lymphoblastic Leukemia-Lymphoma - mortality | Antineoplastic Agents - therapeutic use | Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | DNA Mutational Analysis | Inhibitory Concentration 50 | Female | Antineoplastic Agents - pharmacology | Immunoglobulin Light Chains, Surrogate - genetics | Gene Expression | Genetic Association Studies | Kaplan-Meier Estimate | PAX5 Transcription Factor - genetics | Mice, SCID | Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics | Xenograft Model Antitumor Assays | Animals | Oncogene Proteins, Fusion - genetics | Mice, Inbred NOD | Mutation | Cohort Studies | Gene mutations | Genetic aspects | Acute lymphocytic leukemia | Research | Identification and classification | Health aspects | Risk factors | Bone marrow | Genes | Leukemia | cytarabine | integrative | leukemic stem cell | drug activity profiling | panobinostat | mTOR inhibitor | genomics | glucocorticoids | bortezomib | ABT-199 | dexamethasone | HSP90 | TCF3-PBX1 | vincristine | BH3-mimetics | leukemia xenograft model | next generation sequencing | TCF3-HLF | venetoclax | anthracycline | acute lymphoblastic leukemia | AUY922 | BCL2 | drug resistance | prednisone
Journal Article
by Ripperger, Tim and Bielack, Stefan S and Borkhardt, Arndt and Brecht, Ines B and Burkhardt, Birgit and Calaminus, Gabriele and Debatin, Klaus‐Michael and Deubzer, Hedwig and Dirksen, Uta and Eckert, Cornelia and Eggert, Angelika and Erlacher, Miriam and Fleischhack, Gudrun and Frühwald, Michael C and Gnekow, Astrid and Goehring, Gudrun and Graf, Norbert and Hanenberg, Helmut and Hauer, Julia and Hero, Barbara and Hettmer, Simone and von Hoff, Katja and Horstmann, Martin and Hoyer, Juliane and Illig, Thomas and Kaatsch, Peter and Kappler, Roland and Kerl, Kornelius and Klingebiel, Thomas and Kontny, Udo and Kordes, Uwe and Körholz, Dieter and Koscielniak, Ewa and Kramm, Christof M and Kuhlen, Michaela and Kulozik, Andreas E and Lamottke, Britta and Leuschner, Ivo and Lohmann, Dietmar R and Meinhardt, Andrea and Metzler, Markus and Meyer, Lüder H and Moser, Olga and Nathrath, Michaela and Niemeyer, Charlotte M and Nustede, Rainer and Pajtler, Kristian W and Paret, Claudia and Rasche, Mareike and Reinhardt, Dirk and Rieß, Olaf and Russo, Alexandra and Rutkowski, Stefan and Schlegelberger, Brigitte and Schneider, Dominik and Schneppenheim, Reinhard and Schrappe, Martin and Schroeder, Christopher and von Schweinitz, Dietrich and Simon, Thorsten and Sparber‐Sauer, Monika and Spix, Claudia and Stanulla, Martin and Steinemann, Doris and Strahm, Brigitte and Temming, Petra and Thomay, Kathrin and von Bueren, Andre O and Vorwerk, Peter and Witt, Olaf and Wlodarski, Marcin and Wössmann, Willy and Zenker, Martin and Zimmermann, Stefanie and Pfister, Stefan M and Kratz, Christian P
American Journal of Medical Genetics Part A, ISSN 1552-4825, 04/2017, Volume 173, Issue 4, pp. 1017 - 1037
Journal Article
by Vijayakrishnan, Jayaram and Studd, James and Broderick, Peter and Kinnersley, Ben and Holroyd, Amy and Law, Philip J and Kumar, Rajiv and Allan, James M and Harrison, Christine J and Moorman, Anthony V and Vora, Ajay and Roman, Eve and Rachakonda, Sivaramakrishna and Kinsey, Sally E and Sheridan, Eamonn and Thompson, Pamela D and Irving, Julie A and Koehler, Rolf and Hoffmann, Per and Nöthen, Markus M and Heilmann-Heimbach, Stefanie and Jöckel, Karl-Heinz and Easton, Douglas F and Pharaoh, Paul D.P and Dunning, Alison M and Peto, Julian and Canzian, Frederico and Swerdlow, Anthony and Eeles, Rosalind A and Kote-Jarai, ZSofia and Muir, Kenneth and Pashayan, Nora and Greaves, Mel and Zimmerman, Martin and Bartram, Claus R and Schrappe, Martin and Stanulla, Martin and Hemminki, Kari and Houlston, Richard S and Henderson, Brian E and Haiman, Christopher A and Benlloch, Sara and Schumacher, Fredrick R and Olama, Ali Amin Al and Berndt, Sonja I and Conti, David V and Wiklund, Fredrik and Chanock, Stephen and Stevens, Victoria L and Tangen, Catherine M and Batra, Jyotsna and Clements, Judith and Gronberg, Henrik and Schleutker, Johanna and Albanes, Demetrius and Weinstein, Stephanie and Wolk, Alicja and West, Catharine and Mucci, Lorelei and Cancel-Tassin, Géraldine and Koutros, Stella and Sorensen, Karina Dalsgaard and Maehle, Lovise and Neal, David E and Travis, Ruth C and Hamilton, Robert J and Ingles, Sue Ann and Rosenstein, Barry and Lu, Yong-Jie and Giles, Graham G and Kibel, Adam S and Vega, Ana and Kogevinas, Manolis and Penney, Kathryn L and Park, Jong Y and Stanford, Janet L and Cybulski, Cezary and Nordestgaard, Børge G and Brenner, Hermann and Maier, Christiane and Kim, Jeri and John, Esther M and Teixeira, Manuel R and Neuhausen, Susan L and De Ruyck, Kim and Razack, Azad and Newcomb, Lisa F and Lessel, Davor and Kaneva, Radka and Usmani, Nawaid and Claessens, Frank and Townsend, Paul A and Dominguez, Manuela Gago and Roobol, Monique J and Menegaux, Florence and PRACTICAL Consortium and The PRACTICAL Consortium and Allmänmedicin, psykiatrisk epidemiologi och migration and EpiHealth: Epidemiology for Health and Lund University and Family Medicine, Psychiatric Epidemiology and Migration and Lunds universitet
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 1340 - 9
Journal Article