PLoS ONE, ISSN 1932-6203, 09/2012, Volume 7, Issue 9, p. e45466
Macrophages are dynamic cells integrating signals from their microenvironment to develop specific functional responses. Although, microarray-based...
ACTIVATION | DENDRITIC CELLS | RNA-SEQ | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | DIFFERENTIATION | HUMAN MONOCYTES | POLARIZATION | GENOME | 2B4 CD244 | MOLECULES | Exome | Leukocytes, Mononuclear - metabolism | Macrophages - metabolism | Alternative Splicing | Humans | Gene Expression Regulation | Transcriptome | Immunophenotyping | Gene Expression Profiling | Gene Regulatory Networks | Cluster Analysis | Lipopolysaccharide Receptors - metabolism | Antigens | High resolution | Immunoglobulins | Profiling | Gene clusters | Cytokines | Transcription | Blood & organ donations | Gene regulation | Genomics | Gene expression | Macrophages | Ribonucleic acid--RNA | Cell surface | Gene sequencing | Genotype & phenotype | DNA microarrays | TLR2 protein | Toll-like receptors | Surface markers | RNA | Ribonucleic acid
ACTIVATION | DENDRITIC CELLS | RNA-SEQ | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | DIFFERENTIATION | HUMAN MONOCYTES | POLARIZATION | GENOME | 2B4 CD244 | MOLECULES | Exome | Leukocytes, Mononuclear - metabolism | Macrophages - metabolism | Alternative Splicing | Humans | Gene Expression Regulation | Transcriptome | Immunophenotyping | Gene Expression Profiling | Gene Regulatory Networks | Cluster Analysis | Lipopolysaccharide Receptors - metabolism | Antigens | High resolution | Immunoglobulins | Profiling | Gene clusters | Cytokines | Transcription | Blood & organ donations | Gene regulation | Genomics | Gene expression | Macrophages | Ribonucleic acid--RNA | Cell surface | Gene sequencing | Genotype & phenotype | DNA microarrays | TLR2 protein | Toll-like receptors | Surface markers | RNA | Ribonucleic acid
Journal Article
Glia, ISSN 0894-1491, 09/2013, Volume 61, Issue 9, pp. 1429 - 1442
Microglial cells can be derived directly from the dissociated brain tissue by sorting procedures, from postnatal glial cultures by mechanic isolation or from...
embryonic stem cell‐derived microglia | microglia | primary microglia culture | transcriptome | Embryonic stem cell-derived microglia | Primary microglia culture | Transcriptome | Microglia | YOLK-SAC | MYELOID CELLS | NEUROSCIENCES | MESSENGER-RNA | embryonic stem cell-derived microglia | GENERATION | DERIVE | DIFFERENTIATION | CULTURES | LINEAGE | Animals, Newborn | Green Fluorescent Proteins - metabolism | Brain - cytology | Embryo, Mammalian | Mice, Inbred C57BL | Antigens, Surface - genetics | Cells, Cultured | Computational Biology | Gene Expression Regulation - physiology | Mice, Transgenic | Green Fluorescent Proteins - genetics | CD8-Positive T-Lymphocytes | Animals | Flow Cytometry | Microglia - classification | Microglia - physiology | Microarray Analysis | Antigens, Surface - metabolism | Mice | Neurons - metabolism | Embryonic Stem Cells | Receptors, Chemokine - genetics | Transcriptome - physiology | CX3C Chemokine Receptor 1 | Genetic transcription | T cells | Embryonic stem cells | Analysis | Genomics | Flow cytometry | Stem cells
embryonic stem cell‐derived microglia | microglia | primary microglia culture | transcriptome | Embryonic stem cell-derived microglia | Primary microglia culture | Transcriptome | Microglia | YOLK-SAC | MYELOID CELLS | NEUROSCIENCES | MESSENGER-RNA | embryonic stem cell-derived microglia | GENERATION | DERIVE | DIFFERENTIATION | CULTURES | LINEAGE | Animals, Newborn | Green Fluorescent Proteins - metabolism | Brain - cytology | Embryo, Mammalian | Mice, Inbred C57BL | Antigens, Surface - genetics | Cells, Cultured | Computational Biology | Gene Expression Regulation - physiology | Mice, Transgenic | Green Fluorescent Proteins - genetics | CD8-Positive T-Lymphocytes | Animals | Flow Cytometry | Microglia - classification | Microglia - physiology | Microarray Analysis | Antigens, Surface - metabolism | Mice | Neurons - metabolism | Embryonic Stem Cells | Receptors, Chemokine - genetics | Transcriptome - physiology | CX3C Chemokine Receptor 1 | Genetic transcription | T cells | Embryonic stem cells | Analysis | Genomics | Flow cytometry | Stem cells
Journal Article
Journal of Cell Science, ISSN 0021-9533, 11/2012, Volume 125, Issue 22, pp. 5269 - 5279
Keratin 1 (KRT1) and its heterodimer partner keratin 10 (KRT10) are major constituents of the intermediate filament cytoskeleton in suprabasal epidermis. KRT1...
Keratin cytoskeleton | Epidermal barrier | Innate immunity | Interleukin-18 | Atopic eczema | EPIDERMOLYSIS-BULLOSA SIMPLEX | FILAGGRIN | BARRIER | STRATUM-CORNEUM | CELL BIOLOGY | ATOPIC-DERMATITIS | IN-VITRO | NULL MICE | MUTATIONS | EXPRESSION | Inflammation - pathology | Up-Regulation | Skin - metabolism | Humans | Caspase 1 - metabolism | Keratin-1 - metabolism | Gene Knockdown Techniques | Inflammation - metabolism | Gene Deletion | Protein Structure, Quaternary | Cell Differentiation | Skin - pathology | Skin - immunology | Desmosomes - metabolism | Epidermis - metabolism | Epidermis - pathology | Mice, Inbred C57BL | S100 Proteins - metabolism | Immunity, Innate | Mice, Knockout | Keratinocytes - pathology | Phenotype | Animals | Keratinocytes - metabolism | Mice | Interleukin-18 - metabolism
Keratin cytoskeleton | Epidermal barrier | Innate immunity | Interleukin-18 | Atopic eczema | EPIDERMOLYSIS-BULLOSA SIMPLEX | FILAGGRIN | BARRIER | STRATUM-CORNEUM | CELL BIOLOGY | ATOPIC-DERMATITIS | IN-VITRO | NULL MICE | MUTATIONS | EXPRESSION | Inflammation - pathology | Up-Regulation | Skin - metabolism | Humans | Caspase 1 - metabolism | Keratin-1 - metabolism | Gene Knockdown Techniques | Inflammation - metabolism | Gene Deletion | Protein Structure, Quaternary | Cell Differentiation | Skin - pathology | Skin - immunology | Desmosomes - metabolism | Epidermis - metabolism | Epidermis - pathology | Mice, Inbred C57BL | S100 Proteins - metabolism | Immunity, Innate | Mice, Knockout | Keratinocytes - pathology | Phenotype | Animals | Keratinocytes - metabolism | Mice | Interleukin-18 - metabolism
Journal Article
Journal of the National Cancer Institute, ISSN 0027-8874, 2010, Volume 102, Issue 13, pp. 959 - 971
BACKGROUND: Genome-wide association studies have identified three chromosomal regions at 15q25, 5p15, and 6p21 as being associated with the risk of lung...
NICOTINE DEPENDENCE | POLYMORPHISMS | ONCOLOGY | PROGNOSTIC MARKER | SEQUENCE VARIANTS | RISK | GENETIC-VARIANTS | SMOKING | DNA-REPAIR | GENOME-WIDE ASSOCIATION | TELOMERE LENGTH | Smoking - adverse effects | Japan - epidemiology | Lung Neoplasms - ethnology | Tobacco Use Disorder - ethnology | United States - epidemiology | Carcinoma, Small Cell - genetics | Carcinoma, Squamous Cell - genetics | Humans | Middle Aged | Asian Continental Ancestry Group - genetics | Male | Carcinoma, Large Cell - ethnology | Case-Control Studies | Carcinoma, Squamous Cell - ethnology | Canada - epidemiology | Carcinoma, Small Cell - ethnology | Lung Neoplasms - etiology | Aged, 80 and over | Adult | Female | Tobacco Use Disorder - genetics | Adenocarcinoma - genetics | Carcinoma, Large Cell - genetics | Adenocarcinoma - ethnology | Korea - epidemiology | Odds Ratio | Quality Control | Lung Neoplasms - genetics | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease | Genome-Wide Association Study | Genetic Association Studies | Risk Assessment | Europe | Gene Frequency | Risk Factors | Linkage Disequilibrium - genetics | Genotype | Smoking - genetics | International Cooperation | Chromosomes, Human, Pair 6 | Chromosomes, Human, Pair 5 | Homozygote | Singapore - epidemiology | Chromosomes, Human, Pair 15 | Aged | Polymorphism, Single Nucleotide | Quantitative trait loci | Genetic aspects | Research | Genetic susceptibility | Lung cancer | Risk factors
NICOTINE DEPENDENCE | POLYMORPHISMS | ONCOLOGY | PROGNOSTIC MARKER | SEQUENCE VARIANTS | RISK | GENETIC-VARIANTS | SMOKING | DNA-REPAIR | GENOME-WIDE ASSOCIATION | TELOMERE LENGTH | Smoking - adverse effects | Japan - epidemiology | Lung Neoplasms - ethnology | Tobacco Use Disorder - ethnology | United States - epidemiology | Carcinoma, Small Cell - genetics | Carcinoma, Squamous Cell - genetics | Humans | Middle Aged | Asian Continental Ancestry Group - genetics | Male | Carcinoma, Large Cell - ethnology | Case-Control Studies | Carcinoma, Squamous Cell - ethnology | Canada - epidemiology | Carcinoma, Small Cell - ethnology | Lung Neoplasms - etiology | Aged, 80 and over | Adult | Female | Tobacco Use Disorder - genetics | Adenocarcinoma - genetics | Carcinoma, Large Cell - genetics | Adenocarcinoma - ethnology | Korea - epidemiology | Odds Ratio | Quality Control | Lung Neoplasms - genetics | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease | Genome-Wide Association Study | Genetic Association Studies | Risk Assessment | Europe | Gene Frequency | Risk Factors | Linkage Disequilibrium - genetics | Genotype | Smoking - genetics | International Cooperation | Chromosomes, Human, Pair 6 | Chromosomes, Human, Pair 5 | Homozygote | Singapore - epidemiology | Chromosomes, Human, Pair 15 | Aged | Polymorphism, Single Nucleotide | Quantitative trait loci | Genetic aspects | Research | Genetic susceptibility | Lung cancer | Risk factors
Journal Article
The EMBO Journal, ISSN 0261-4189, 01/2012, Volume 31, Issue 1, pp. 201 - 213
Early during Gram‐negative sepsis, excessive release of pro‐inflammatory cytokines can cause septic shock that is often followed by a state of immune paralysis...
dendritic cells | T cells | type I IFN | sepsis | splenic macrophages | Tcells | TRANSCRIPTION FACTORS | IFN-ALPHA/BETA | GENE INDUCTION | BIOCHEMISTRY & MOLECULAR BIOLOGY | RECEPTOR 4 | CUTTING EDGE | CELL BIOLOGY | INFECTION | T-CELLS | CROSS-PRESENTATION | ANTIGEN | Adaptive Immunity | Sepsis - immunology | Macrophages - pathology | Signal Transduction | Mice, Inbred C57BL | Toll-Like Receptor 4 - metabolism | Macrophages - metabolism | Animals | Spleen - metabolism | Sepsis - metabolism | Interferon Type I - metabolism | Mice | Myeloid Differentiation Factor 88 - metabolism | Dendritic Cells - metabolism | Signal transduction | Sepsis | Gene expression | Immune system
dendritic cells | T cells | type I IFN | sepsis | splenic macrophages | Tcells | TRANSCRIPTION FACTORS | IFN-ALPHA/BETA | GENE INDUCTION | BIOCHEMISTRY & MOLECULAR BIOLOGY | RECEPTOR 4 | CUTTING EDGE | CELL BIOLOGY | INFECTION | T-CELLS | CROSS-PRESENTATION | ANTIGEN | Adaptive Immunity | Sepsis - immunology | Macrophages - pathology | Signal Transduction | Mice, Inbred C57BL | Toll-Like Receptor 4 - metabolism | Macrophages - metabolism | Animals | Spleen - metabolism | Sepsis - metabolism | Interferon Type I - metabolism | Mice | Myeloid Differentiation Factor 88 - metabolism | Dendritic Cells - metabolism | Signal transduction | Sepsis | Gene expression | Immune system
Journal Article
Expert Review of Molecular Diagnostics, ISSN 1473-7159, 04/2009, Volume 9, Issue 3, pp. 271 - 280
In 1999, Golub et al. proposed for the first time microarray-based transcriptional profiling to be used as a new technology for the differential diagnosis of...
Molecular diagnostics | Transcriptomics | DNA | Leukemia | Inflammation | Molecular profiling | Gene expression | Microarray | Blood | leukemia | molecular diagnostics | GENE-EXPRESSION SIGNATURE | SYSTEMIC-LUPUS-ERYTHEMATOSUS | ACUTE-MYELOID-LEUKEMIA | MONONUCLEAR-CELLS | PERIPHERAL-BLOOD | PATHOLOGY | blood | BREAST-CANCER | MOLECULAR CLASSIFICATION | microarray | B-CELL LYMPHOMA | inflammation | ACUTE LYMPHOBLASTIC-LEUKEMIA | transcriptomics | gene expression | MICROARRAY DATA | molecular profiling | Autoimmune Diseases - genetics | Oligonucleotide Array Sequence Analysis - methods | Humans | Leukemia - diagnosis | Gene Expression Profiling - methods | Autoimmune Diseases - diagnosis | Leukemia - genetics | Leukemia - classification
Molecular diagnostics | Transcriptomics | DNA | Leukemia | Inflammation | Molecular profiling | Gene expression | Microarray | Blood | leukemia | molecular diagnostics | GENE-EXPRESSION SIGNATURE | SYSTEMIC-LUPUS-ERYTHEMATOSUS | ACUTE-MYELOID-LEUKEMIA | MONONUCLEAR-CELLS | PERIPHERAL-BLOOD | PATHOLOGY | blood | BREAST-CANCER | MOLECULAR CLASSIFICATION | microarray | B-CELL LYMPHOMA | inflammation | ACUTE LYMPHOBLASTIC-LEUKEMIA | transcriptomics | gene expression | MICROARRAY DATA | molecular profiling | Autoimmune Diseases - genetics | Oligonucleotide Array Sequence Analysis - methods | Humans | Leukemia - diagnosis | Gene Expression Profiling - methods | Autoimmune Diseases - diagnosis | Leukemia - genetics | Leukemia - classification
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 05/2011, Volume 17, Issue 10, pp. 3360 - 3367
Purpose: Blood-based surrogate markers would be attractive biomarkers for early detection, diagnosis, prognosis, and prediction of therapeutic outcome in...
MONONUCLEAR-CELLS | PATTERNS | PROFILES | SET ENRICHMENT ANALYSIS | ONCOLOGY | CARCINOMA | Lung Neoplasms - genetics | Leukocytes, Mononuclear - metabolism | Oligonucleotide Array Sequence Analysis | Carcinoma, Non-Small-Cell Lung - genetics | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Male | Gene Expression Profiling | Case-Control Studies | Lung Neoplasms - classification | Algorithms | Carcinoma, Non-Small-Cell Lung - classification | Adult | Carcinoma, Non-Small-Cell Lung - blood | Female | Aged | Lung Neoplasms - blood
MONONUCLEAR-CELLS | PATTERNS | PROFILES | SET ENRICHMENT ANALYSIS | ONCOLOGY | CARCINOMA | Lung Neoplasms - genetics | Leukocytes, Mononuclear - metabolism | Oligonucleotide Array Sequence Analysis | Carcinoma, Non-Small-Cell Lung - genetics | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Male | Gene Expression Profiling | Case-Control Studies | Lung Neoplasms - classification | Algorithms | Carcinoma, Non-Small-Cell Lung - classification | Adult | Carcinoma, Non-Small-Cell Lung - blood | Female | Aged | Lung Neoplasms - blood
Journal Article
Journal of Hepatology, ISSN 0168-8278, 2013, Volume 59, Issue 2, pp. 229 - 235
Background & Aims Regulatory CD4+ T cells (Tregs) are considered to affect outcomes of HCV infection, because they increase in number during chronic hepatitis...
Gastroenterology and Hepatology | Hepatic stellate cells | Hepatitis C virus | Regulatory T cells | IL-8 | Fibrogenesis | Regulatory | T cells | LOCALIZATION | MESSENGER-RNA EXPRESSION | STELLATE CELLS | ALPHA | INTERLEUKIN-8 | IN-VITRO PROLIFERATION | LIVER | INFECTED PATIENTS | VIRUS CORE PROTEIN | GASTROENTEROLOGY & HEPATOLOGY | LYMPHOCYTES | Adaptive Immunity | Biomarkers - metabolism | T-Lymphocytes, Regulatory - metabolism | Up-Regulation | Hepatitis C, Chronic - pathology | Liver - pathology | T-Lymphocytes, Regulatory - classification | Interleukin-8 - biosynthesis | Humans | Middle Aged | Hepatic Stellate Cells - metabolism | Male | Disease Progression | T-Lymphocytes, Regulatory - immunology | Young Adult | Liver - immunology | Hepatic Stellate Cells - immunology | Forkhead Transcription Factors - metabolism | Fibrosis | Hepatitis C, Chronic - immunology | Adult | Female | Aged
Gastroenterology and Hepatology | Hepatic stellate cells | Hepatitis C virus | Regulatory T cells | IL-8 | Fibrogenesis | Regulatory | T cells | LOCALIZATION | MESSENGER-RNA EXPRESSION | STELLATE CELLS | ALPHA | INTERLEUKIN-8 | IN-VITRO PROLIFERATION | LIVER | INFECTED PATIENTS | VIRUS CORE PROTEIN | GASTROENTEROLOGY & HEPATOLOGY | LYMPHOCYTES | Adaptive Immunity | Biomarkers - metabolism | T-Lymphocytes, Regulatory - metabolism | Up-Regulation | Hepatitis C, Chronic - pathology | Liver - pathology | T-Lymphocytes, Regulatory - classification | Interleukin-8 - biosynthesis | Humans | Middle Aged | Hepatic Stellate Cells - metabolism | Male | Disease Progression | T-Lymphocytes, Regulatory - immunology | Young Adult | Liver - immunology | Hepatic Stellate Cells - immunology | Forkhead Transcription Factors - metabolism | Fibrosis | Hepatitis C, Chronic - immunology | Adult | Female | Aged
Journal Article
Journal of Molecular Diagnostics, The, ISSN 1525-1578, 2011, Volume 13, Issue 4, pp. 452 - 460
Microarray-based transcriptome analysis of peripheral blood as surrogate tissue has become an important approach in clinical implementations. However,...
Pathology | BREAST-CANCER | RESPONSES | PROFILES | CLINICAL-TRIALS | DISEASE | PATTERNS | CRYOPRESERVATION | LEUKEMIA | PATHOLOGY | LYMPHOCYTE IMMUNOPHENOTYPE | GENE-EXPRESSION SIGNATURES | Melanoma - blood | Oligonucleotide Array Sequence Analysis - methods | Humans | Middle Aged | Gene Expression Profiling - methods | Male | Leukocytes, Mononuclear | RNA Stability | Blood | Young Adult | Time Factors | Cryopreservation | Melanoma - genetics | Adult | Female | Aged | Cluster Analysis | Regular
Pathology | BREAST-CANCER | RESPONSES | PROFILES | CLINICAL-TRIALS | DISEASE | PATTERNS | CRYOPRESERVATION | LEUKEMIA | PATHOLOGY | LYMPHOCYTE IMMUNOPHENOTYPE | GENE-EXPRESSION SIGNATURES | Melanoma - blood | Oligonucleotide Array Sequence Analysis - methods | Humans | Middle Aged | Gene Expression Profiling - methods | Male | Leukocytes, Mononuclear | RNA Stability | Blood | Young Adult | Time Factors | Cryopreservation | Melanoma - genetics | Adult | Female | Aged | Cluster Analysis | Regular
Journal Article
Respiratory Research, ISSN 1465-9921, 02/2010, Volume 11, Issue 1, pp. 18 - 18
Background: Lung cancer is a very frequent and lethal tumor with an identifiable risk population. Cytological analysis and chest X-ray failed to reduce...
AUTOANTIBODIES | ANTIBODIES | MICROARRAY | RESPIRATORY SYSTEM | HUMORAL IMMUNE-RESPONSE | PROTEIN EXPRESSION | UPDATE | STAGE-I | PROTEOMICS-BASED IDENTIFICATION | COMPUTED-TOMOGRAPHY | TUMOR-ANTIGEN | Blood Chemical Analysis - methods | Reproducibility of Results | Humans | Middle Aged | Male | Biomarkers, Tumor - blood | Algorithms | Sensitivity and Specificity | Diagnosis, Computer-Assisted - methods | Female | Neoplasm Proteins - blood | Aged | Lung Neoplasms - blood | Lung Neoplasms - diagnosis | CT imaging | Usage | Medical examination | Lung cancer | Diagnosis | Research | Health aspects | Blood | Heart attacks | Disease | Heart surgery | Mortality | Studies | Confidence intervals | Accuracy | Hospitals | Tomography | Chronic obstructive pulmonary disease | Drug dosages | Age | Smoking | Tumors
AUTOANTIBODIES | ANTIBODIES | MICROARRAY | RESPIRATORY SYSTEM | HUMORAL IMMUNE-RESPONSE | PROTEIN EXPRESSION | UPDATE | STAGE-I | PROTEOMICS-BASED IDENTIFICATION | COMPUTED-TOMOGRAPHY | TUMOR-ANTIGEN | Blood Chemical Analysis - methods | Reproducibility of Results | Humans | Middle Aged | Male | Biomarkers, Tumor - blood | Algorithms | Sensitivity and Specificity | Diagnosis, Computer-Assisted - methods | Female | Neoplasm Proteins - blood | Aged | Lung Neoplasms - blood | Lung Neoplasms - diagnosis | CT imaging | Usage | Medical examination | Lung cancer | Diagnosis | Research | Health aspects | Blood | Heart attacks | Disease | Heart surgery | Mortality | Studies | Confidence intervals | Accuracy | Hospitals | Tomography | Chronic obstructive pulmonary disease | Drug dosages | Age | Smoking | Tumors
Journal Article
Cell Reports, ISSN 2211-1247, 03/2013, Volume 3, Issue 3, pp. 779 - 795
Development of CD8 T cell (CTL) immunity or tolerance is linked to the conditions during T cell priming. Dendritic cells (DCs) matured during inflammation...
DELETIONAL TOLERANCE | MOLECULAR SIGNATURE | DENDRITIC CELLS | SINUSOIDAL ENDOTHELIAL-CELLS | PERIPHERAL TOLERANCE | IN-VIVO | ANTIGEN PRESENTATION | STEADY-STATE | TRANSCRIPTION FACTOR | VIRAL-INFECTION | CELL BIOLOGY | Neuropilin-1 - genetics | Receptors, Interleukin-12 - immunology | Lymphocyte Activation | Neuropilin-1 - metabolism | Dendritic Cells - immunology | Mice, Inbred C57BL | Liver - microbiology | CD28 Antigens - immunology | Gene Expression Profiling | Listeria monocytogenes - immunology | Immunity, Innate | Endothelial Cells - immunology | Liver - immunology | Animals | Cross-Priming | Immunologic Memory | Receptors, Antigen, T-Cell - immunology | Liver - cytology | Mice | CD8-Positive T-Lymphocytes - immunology
DELETIONAL TOLERANCE | MOLECULAR SIGNATURE | DENDRITIC CELLS | SINUSOIDAL ENDOTHELIAL-CELLS | PERIPHERAL TOLERANCE | IN-VIVO | ANTIGEN PRESENTATION | STEADY-STATE | TRANSCRIPTION FACTOR | VIRAL-INFECTION | CELL BIOLOGY | Neuropilin-1 - genetics | Receptors, Interleukin-12 - immunology | Lymphocyte Activation | Neuropilin-1 - metabolism | Dendritic Cells - immunology | Mice, Inbred C57BL | Liver - microbiology | CD28 Antigens - immunology | Gene Expression Profiling | Listeria monocytogenes - immunology | Immunity, Innate | Endothelial Cells - immunology | Liver - immunology | Animals | Cross-Priming | Immunologic Memory | Receptors, Antigen, T-Cell - immunology | Liver - cytology | Mice | CD8-Positive T-Lymphocytes - immunology
Journal Article
International Immunology, ISSN 0953-8178, 05/2013, Volume 25, Issue 5, pp. 307 - 317
Vav1 regulates MHC Class II transcription and surface expression in antigen-presenting cells.Vav1 is a guanine nucleotide exchange factor (GEF) for Rho...
Antigen presenting cells | Guanine nucleotide exchange factor | Microarray analysis | TRANSCRIPTIONAL ACTIVATION | microarray analysis | DENDRITIC CELLS | AZATHIOPRINE | IMMUNOLOGY | FAMILY | guanine nucleotide exchange factor | NUCLEOTIDE EXCHANGE ACTIVITY | PATHWAY | RHO-GTPASES | PROTEINS | ANTIGEN RECEPTOR | antigen presenting cells | T-CELLS | B-Lymphocytes - cytology | Lymphocyte Activation | Mice, Inbred C57BL | Proto-Oncogene Proteins c-vav - deficiency | Male | Animals | Female | Histocompatibility Antigens Class II - metabolism | Mice | Mice, Inbred BALB C | Histocompatibility Antigens Class II - genetics | B-Lymphocytes - metabolism | Proto-Oncogene Proteins c-vav - metabolism
Antigen presenting cells | Guanine nucleotide exchange factor | Microarray analysis | TRANSCRIPTIONAL ACTIVATION | microarray analysis | DENDRITIC CELLS | AZATHIOPRINE | IMMUNOLOGY | FAMILY | guanine nucleotide exchange factor | NUCLEOTIDE EXCHANGE ACTIVITY | PATHWAY | RHO-GTPASES | PROTEINS | ANTIGEN RECEPTOR | antigen presenting cells | T-CELLS | B-Lymphocytes - cytology | Lymphocyte Activation | Mice, Inbred C57BL | Proto-Oncogene Proteins c-vav - deficiency | Male | Animals | Female | Histocompatibility Antigens Class II - metabolism | Mice | Mice, Inbred BALB C | Histocompatibility Antigens Class II - genetics | B-Lymphocytes - metabolism | Proto-Oncogene Proteins c-vav - metabolism
Journal Article
BMC Research Notes, ISSN 1756-0500, 2012, Volume 5, Issue 1, pp. 2 - 2
This study analyses the effect of active participation in a sports club, physical activity and social networks on the development of lung cancer in patients...
Social network | Smokers | Physical activity | Sports club | Lung cancer | Germany | Smoking - adverse effects | Adenocarcinoma - pathology | Adenocarcinoma of Lung | Social Networking | Adenocarcinoma - etiology | Humans | Middle Aged | Risk Factors | Lung Neoplasms - pathology | Male | Urban Population | Motor Activity | Case-Control Studies | Lung Neoplasms - etiology | Rural Population | Adult | Female | Surveys and Questionnaires | Aged | Retrospective Studies | Sports | Exercise | Oncology, Experimental | Physiological aspects | Development and progression | Research | Health aspects | Risk factors | Smoking | Cancer | Studies | Social networks | Mortality | Social support
Social network | Smokers | Physical activity | Sports club | Lung cancer | Germany | Smoking - adverse effects | Adenocarcinoma - pathology | Adenocarcinoma of Lung | Social Networking | Adenocarcinoma - etiology | Humans | Middle Aged | Risk Factors | Lung Neoplasms - pathology | Male | Urban Population | Motor Activity | Case-Control Studies | Lung Neoplasms - etiology | Rural Population | Adult | Female | Surveys and Questionnaires | Aged | Retrospective Studies | Sports | Exercise | Oncology, Experimental | Physiological aspects | Development and progression | Research | Health aspects | Risk factors | Smoking | Cancer | Studies | Social networks | Mortality | Social support
Journal Article
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Full Text
Unique transcriptome signature of mouse microglia
: Transcriptome Analysis of Microglia
Glia, ISSN 0894-1491, 09/2013, Volume 61, Issue 9, pp. 1429 - 1442
Journal Article