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chemistry, organic (16) 16
chemistry (4) 4
derivatives (4) 4
isoquinoline (4) 4
polyphosphoric acid (4) 4
acids (3) 3
acyl chlorides (3) 3
cyclization (3) 3
synthesis (3) 3
alpha-amidoalkylation (2) 2
amidoalkylation (2) 2
asymmetric-synthesis (2) 2
biochemistry, general (2) 2
chemistry, medicinal (2) 2
c‐c bond formation (2) 2
enaminones (2) 2
fused pyridine derivatives (2) 2
isoquinoline derivatives (2) 2
n-acyliminium ions (2) 2
oxidation (2) 2
1,4-benzodiazepines (1) 1
1-acylpyridinium salts (1) 1
3-phenylurea (1) 1
4-aminobenzyl (1) 1
4-aminophenyl (1) 1
4-dihydroisoquinolines (1) 1
4-dimethoxyphenyl (1) 1
acid-induced (1) 1
acylation (1) 1
agents (1) 1
aldehydes (1) 1
algorithms (1) 1
alkaloid (1) 1
alkaloids (1) 1
alkyl 2-acylphenylacetates (1) 1
alkyl chloroformate (1) 1
allylation (1) 1
alpha-amidoalkylation reaction (1) 1
amide formation (1) 1
amination, n‐alkylation, n‐arylation (1) 1
aminobenzophenones (1) 1
analogs (1) 1
antagonist (1) 1
antagonists (1) 1
antibacterial (1) 1
anticonvulsant activity (1) 1
antimalarial activity (1) 1
antioxidant (1) 1
antitumor activity (1) 1
antitumor-activity (1) 1
assisted extraction (1) 1
benzimidazole (1) 1
benzodiazepine intermediates (1) 1
beta-carbolines (1) 1
biomedicine (1) 1
biophysics/biomedical physics (1) 1
bulgaria (1) 1
carboxylic (1) 1
carboxylic-acids (1) 1
catalytic amount (1) 1
cell biology (1) 1
chemistry, applied (1) 1
chemistry, multidisciplinary (1) 1
chemistry/food science, general (1) 1
chloroformate (1) 1
chromium compounds (1) 1
complex (1) 1
configuration (1) 1
construction (1) 1
crucifers (1) 1
crystallography (1) 1
dicarbonyl compounds (1) 1
electrophilic alpha-amidoalkylation (1) 1
enamide (1) 1
enamides (1) 1
enaminoketones (1) 1
facile addition (1) 1
facile synthesis (1) 1
flavonoids (1) 1
flavonoids - analysis (1) 1
flavonoids - isolation & purification (1) 1
flavonoids - pharmacology (1) 1
free radical scavengers - analysis (1) 1
free radical scavengers - isolation & purification (1) 1
free radical scavengers - pharmacology (1) 1
friedel-crafts acylation (1) 1
fused pyrimidine derivatives (1) 1
geochemistry (1) 1
harmaline (1) 1
heteroaromatics (1) 1
heterocycles (1) 1
homoveratrylamine (1) 1
hydroxybenzoates - analysis (1) 1
hydroxyl group (1) 1
imidazole (1) 1
index medicus (1) 1
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intermolecular addition-reactions (1) 1
isochromanes (1) 1
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Journal of Heterocyclic Chemistry, ISSN 0022-152X, 07/2018, Volume 55, Issue 7, pp. 1589 - 1595
Camalexin is synthesized on a gram scale by coupling of thiazole and indole in an amidoalkylation–oxidation sequence. Several high‐yielding implementations of... 
ALKYL CHLOROFORMATE | N-ACYLIMINIUM IONS | ASYMMETRIC-SYNTHESIS | ACYL CHLORIDES | ALPHA-AMIDOALKYLATION | INTERMOLECULAR ADDITION-REACTIONS | PHYTOALEXIN CAMALEXIN | CHEMISTRY, ORGANIC | 1-ACYLPYRIDINIUM SALTS | CRUCIFERS | REGIOSELECTIVE ADDITION
Journal Article
Arkivoc, ISSN 1551-7012, 08/2013, Volume 2013, Issue 4, pp. 126 - 133
N-Acyliminium reagents derived from benzimidazole have been used successfully in C-C bond forming reactions with beta-enaminones. The new 2-substituted... 
Enaminones | α-amidoalkylation | N-Acyliminium | N-ACYLIMINIUM IONS | ACYL CHLORIDES | CHEMISTRY, ORGANIC | AMIDOALKYLATION | enaminones | alpha-amidoalkylation
Journal Article
Synthetic Communications, ISSN 0039-7911, 06/2006, Volume 36, Issue 10, pp. 1405 - 1411
A number of aminobenzophenones have been synthesized by acylation of benzene and its derivatives with different 2-,3-,4-aminobenzoic and 4-aminophenylacetic... 
polyphosphoric acid | Friedel-Crafts acylation | Aminobenzophenones | benzodiazepine intermediates | nonlinear optic | Nonlinear optic | Polyphosphoric acid | Benzodiazepine intermediates | 1,4-BENZODIAZEPINES | aminobenzophenones | CHEMISTRY, ORGANIC | INHIBITORS
Journal Article
Arkivoc, ISSN 1551-7012, 09/2007, Volume 2007, Issue 15, pp. 31 - 44
A series of 1-substituted isochromanes has been synthesized from the corresponding alkyl 2-acylphenylacetates 3, by reduction and cyclization with a catalytic... 
Alkyl 2-acylphenylacetates | Reduction | Isochromanes | Synthesis | Sodium borohydride | synthesis | OXIDATION | isochromanes | HYDROXYL GROUP | METABOLITES | sodium borohydride | ANALOGS | CONFIGURATION | CHEMISTRY, ORGANIC | ALDEHYDES | alkyl 2-acylphenylacetates | ISOCOUMARINS | reduction | DERIVATIVES | CYCLIZATION
Journal Article
Heterocycles, ISSN 0385-5414, 10/2005, Volume 65, Issue 10, pp. 2483 - 2492
A number of 1-substituted 3,4-dihydro-9H-beta-carboline derivatives (4) with high purity and yields have been synthesized by treating of tryptamine (1) with... 
CHEMISTRY, ORGANIC | MANZAMINE ALKALOIDS | SPONGE | NONREARRANGED MONOTERPENOID UNIT | HARMALINE | SIMPLE INDOLE ALKALOIDS
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 2007, Volume 48, Issue 38, pp. 6674 - 6676
A series of cyclic enaminoketones were selectively amidoalkylated at the α-carbon in reactions with acyliminium reagents derived from 3,4-dihydroisoquinolines.... 
ACYL CHLORIDES | ISOQUINOLINE | SILYL ENOL ETHERS | ALLYLATION | FACILE ADDITION | CHEMISTRY, ORGANIC | CHLOROFORMATE | CATALYTIC AMOUNT | Ketones | Chromium compounds
Journal Article
Arkivoc, ISSN 1551-7012, 06/2007, Volume 2007, Issue 15, pp. 11 - 17
The selective acylation of the aromatic ring of N-phenethyl enaminones is reported. A number of substituents in the beta-enaminone structure and in the benzene... 
Dicarbonyl compounds | Enaminones | Homoveratrylamine | Regioselective acylation | dicarbonyl compounds | homoveratrylamine | ENAMINOKETONES | regioselective acylation | ANTICONVULSANT ACTIVITY | ACIDS | REACTIVITY | CHEMISTRY | CHEMISTRY, ORGANIC | enaminones
Journal Article
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, ISSN 2056-9890, 09/2008, Volume 64, Issue 9, pp. O1796 - U2298
In the title compound, C18H22N2O4, the dihedral angle between the pyrrolyl and quinolinyl fragments is 68.97 (2)degrees. Two non-classical intramolecular C-H... 
CRYSTALLOGRAPHY
Journal Article
Heterocycles, ISSN 0385-5414, 02/2006, Volume 68, Issue 2, pp. 369 - 374
1-Substituted 3,4-dihydro- and 1,2,3,4-tetrahydroisoquinoline derivatives were obtained in high yields from reactions of 2-(3,4-dimethoxyphenyl)ethylamine with... 
ANTAGONIST | ISOQUINOLINE | CHEMISTRY, ORGANIC | ANTIMALARIAL ACTIVITY | POLYPHOSPHORIC ACID | PROTOBERBERINE ALKALOIDS | CARBOXYLIC-ACIDS
Journal Article
Heterocycles, ISSN 0385-5414, 02/2006, Volume 68, Issue 2, pp. 387 - 393
N-Formylenamides of isoquinoline (6) were obtained from N-[2-(2-acyl-4,5 -dimethoxyphenyl)ethyl] formamides (5) by cyclization in the presence of catalytic... 
CHEMISTRY, ORGANIC | DERIVATIVES | ENAMIDES
Journal Article
Synthetic Communications, ISSN 0039-7911, 01/2004, Volume 34, Issue 15, pp. 2813 - 2821
N-Acyliminium reagents formed from 3,4-dihydro-β-carboline and acyl chlorides were used for amidoalkylation of indole, pyrrole, and thiophene. # This paper is... 
Alkaloids | N-Acyliminium reagents | β-Carbolines | Heteroaromatics | α-Amidoalkylation reaction | α-Midoalkylation reaction | beta-carbolines | N-acyliminium reagents | heteroaromatics | alkaloids | CHEMISTRY, ORGANIC | alpha-amidoalkylation reaction | TUNICATE EUDISTOMA-GLAUCUS
Journal Article
Heterocycles, ISSN 0385-5414, 07/2006, Volume 68, Issue 7, pp. 1443 - 1449
A general synthesis of a series 4-substituted 3,4-dihydro-2(1H)-quinazolinones (7) included polyphosphoric acid (PPA)-induced cyclization with carboxylic... 
CHEMISTRY, ORGANIC | POTENT | COMPLEX | ANTAGONISTS | DERIVATIVES | UREAS
Journal Article
Central European Journal of Chemistry, ISSN 1895-1066, 3/2004, Volume 2, Issue 1, pp. 234 - 246
The N-acyliminium intermediates of 3,4-dihydroisoquinoline and salts of isoquinoline with acyl chlorides were successfully used as amidoalkylating reagents... 
Biochemistry, general | Biophysics/Biomedical Physics | Chemistry | amidoalkylation | isoquinoline | Chemistry/Food Science, general | heterocycles | Geochemistry | Isoquinoline | Amidoalkylation | Heterocycles | ASYMMETRIC-SYNTHESIS | ELECTROPHILIC ALPHA-AMIDOALKYLATION | CHEMISTRY, MULTIDISCIPLINARY
Journal Article
Medicinal Chemistry Research, ISSN 1054-2523, 12/2005, Volume 14, Issue 8, pp. 429 - 439
A new series of 1,2,3-trisubstituted 2-(2-oxoalkyl)-2,3-dihydrobezimidazoles have been synthesized and evaluated for their cytotoxic activity using one normal... 
Biochemistry, general | Biomedicine | Pharmacology/Toxicology | Cell Biology | CHEMISTRY, MEDICINAL | QUINONES | BENZIMIDAZOLE | ANTIBACTERIAL | AGENTS | ANTITUMOR-ACTIVITY | IMIDAZOLE | DERIVATIVES
Journal Article
Tetrahedron, ISSN 0040-4020, 01/1996, Volume 52, Issue 4, pp. 1451 - 1460
Synthesis of 3,4-dihydroisoquinolines 2, 2-alkyl-6 and 2-acyl-3,4-dihydro-1(2H)-isoquinolinones 9, 2-alkyl-1(2H)-isoquinolinones 14,... 
Journal Article
Acta crystallographica. Section E, Structure reports online, ISSN 1600-5368, 08/2008, Volume 64, Issue Pt 9, p. o1796
In the title compound, C(18)H(22)N(2)O(4), the dihedral angle between the pyrrolyl and quinolinyl fragments is 68.97 (2)°. Two non-classical intra-molecular... 
Journal Article
Acta Crystallographica Section E: Structure Reports Online, ISSN 1600-5368, 2008, Volume 64, Issue 9, p. o1796
Journal Article
Tetrahedron, ISSN 0040-4020, 1996, Volume 52, Issue 4, pp. 1451 - 1460
Synthesis of 3,4-dihydroisoquinolines 2,2-alkyl- 6 and 2-acyl-3,4-dihydro -1(2H)-isoquinolinones 9, 2-alkyl-1(2H)- isoquinolinones 14,... 
SALT | CHEMISTRY | CHEMISTRY, ORGANIC | SERIES | ACIDS
Journal Article
Synthetic Communications, ISSN 0039-7911, 05/1998, Volume 28, Issue 10, pp. 1857 - 1864
Adducts 4 of benzimidazoles and acyl chlorides were successfully used as electrophilic reagents in an intermolecular α-amidoalkylation reaction toward ketones... 
CHEMISTRY, ORGANIC
Journal Article
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