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FRONTIERS IN IMMUNOLOGY, ISSN 1664-3224, 08/2019, Volume 10
Factor XII (FXII) is the zymogen of serine protease, factor XIIa (FXIIa). FXIIa enzymatic activities have been extensively studied and FXIIa inhibition is... 
INDUCED MITOGENESIS | CONTACT SYSTEM | wound healing | neutrophil extracellular traps | THROMBUS FORMATION | contact activation | IMMUNOLOGY | PLASMINOGEN-ACTIVATOR RECEPTOR | COAGULATION-FACTOR-XII | PLASMA | innate immunity | cancer progression | uPAR | INFLAMMATORY RESPONSE | METAL-IONS | FACTOR-XA | sepsis | factor XII | UROKINASE
Journal Article
Cytometry Part B: Clinical Cytometry, ISSN 1552-4949, 03/2018, Volume 94, Issue 2, pp. 369 - 373
Journal Article
Blood, ISSN 0006-4971, 09/2015, Volume 126, Issue 11, pp. 1379 - 1389
Journal Article
Frontiers in Medicine, 04/2016, Volume 3
Plasma kallikrein formed from prekallikrein (PK) produces bradykinin from kininogens and activates factor XII. Plasma PK is activated by factors XIIa, XIIa... 
PEACE Trial | Prolylcarboxypeptidase | PRCP | Prekallikrein | KLKB1
Journal Article
Blood, ISSN 0006-4971, 01/2015, Volume 125, Issue 4, pp. 710 - 719
The precise mechanism for reduced thrombosis in prekallikrein null mice (Klkb1(-/-)) is unknown. Klkb1(-/-) mice have delayed carotid artery occlusion times on... 
PLASMA KALLIKREIN | MOLECULAR-WEIGHT KININOGEN | ENDOTHELIAL-CELLS | IN-VIVO | NITRIC-OXIDE | FACTOR EXPRESSION | VASCULAR-PERMEABILITY | DEFICIENT MICE | CONTACT ACTIVATION | HEMATOLOGY | FACTOR-XII | Epoprostenol - genetics | Receptor, Bradykinin B2 - genetics | Receptors, G-Protein-Coupled - metabolism | Epoprostenol - biosynthesis | Peptide Fragments - pharmacology | Carotid Artery Thrombosis - metabolism | Pyrones - pharmacology | Sirtuin 1 - genetics | Thromboplastin - antagonists & inhibitors | Nerve Tissue Proteins - biosynthesis | Synaptotagmins - biosynthesis | Carotid Artery Thrombosis - chemically induced | Prekallikrein | Thromboplastin - biosynthesis | Proto-Oncogene Proteins - metabolism | Kruppel-Like Transcription Factors - biosynthesis | Proto-Oncogene Proteins - antagonists & inhibitors | Angiotensin II - pharmacology | Receptor, Bradykinin B2 - biosynthesis | Sirtuin 1 - biosynthesis | Proto-Oncogene Proteins - genetics | Imidazoles - pharmacology | Angiotensin II - analogs & derivatives | Sulfonamides - pharmacology | Nerve Tissue Proteins - genetics | Sirtuin 1 - antagonists & inhibitors | Mice, Knockout | Naphthalenes - pharmacology | Animals | Partial Thromboplastin Time | Thromboplastin - genetics | Receptors, G-Protein-Coupled - antagonists & inhibitors | Mice | Receptors, G-Protein-Coupled - genetics | Synaptotagmins - genetics | Carotid Artery Thrombosis - genetics | Carotid Artery Thrombosis - pathology | Kruppel-Like Transcription Factors - antagonists & inhibitors | Kruppel-Like Transcription Factors - genetics | RNA, Messenger | Index Medicus | Abridged Index Medicus | Thrombosis and Hemostasis
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 03/2018, Volume 128, Issue 3, pp. 944 - 959
Journal Article
2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), ISSN 1557-170X, 08/2016, Volume 2016-, pp. 291 - 294
This paper describes the design and construct of a fully biocompatible, microfluidic, dielectric sensor targeted at monitoring human whole blood coagulation at... 
Electrodes | Dielectric measurement | Dielectrics | Permittivity | Microfluidics | Coagulation | Microfluidics - instrumentation | Electricity | Point-of-Care Systems | Time Factors | Humans | Titanium - chemistry | Blood Coagulation - physiology | Polymethyl Methacrylate - chemistry | Microfluidics - methods | Index Medicus
Conference Proceeding
Journal Article
Journal Article
Research and Practice in Thrombosis and Haemostasis, ISSN 2475-0379, 06/2019
Journal Article
Frontiers in medicine, ISSN 2296-858X, 2016, Volume 3, pp. 17 - 17
Plasma kallikrein formed from prekallikrein (PK) produces bradykinin from kininogens and activates factor XII. Plasma PK is activated by factors αXIIa, βXIIa,... 
Enzymes | Medical research | Kallikrein | Medicine, Experimental | Genetic aspects | Research | Cardiovascular diseases
Journal Article
Blood advances, 08/2019, Volume 3, Issue 15, pp. 2312 - 2316
Journal Article
04/2014, ISBN 0470670509, 15
Factor XII (FXII) is a serine protease that was thought to initiate hemostasis. However, FXII‐deficient patients do not have a bleeding state. Recent... 
thrombosis | inflammation | angiogenesis | Hageman factor | plasma kallikrein/kinin system | contact activation | factor XII
Book Chapter
Book Chapter
01/2014, ISBN 0124052061
Current concepts suggest that the basic mechanisms of venous and arterial thrombosis are different variations of similar pathogenetic pathways. Both venous and... 
Pathology | Other | Kruppel-like factors | NETs | Nrf2 | PGI2 | Tissue factor | Homocysteine | Thrombomodulin | SIRT1
Book Chapter
Thrombosis Research, ISSN 0049-3848, 07/2019, Volume 179, pp. 56 - 63
Wound healing is a complex process that consists of multiple phases, each of which are indispensable for adequate repair. Timely initiation and resolution of... 
Coagulation factors | Chronic wounds | Platelets | Macrophages | Cutaneous wound healing | Neutrophils | Medical colleges | Care and treatment | Hospitals | Wound healing | Tissue plasminogen activator | Proteases | Von Willebrand factor | Wounds and injuries | Growth factors
Journal Article