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Cancer Cell, ISSN 1535-6108, 07/2015, Volume 28, Issue 1, pp. 3 - 4
Journal Article
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2014, Volume 9, Issue 9, p. e106983
Reversing the escalating rate of obesity requires increased knowledge of the molecular mechanisms controlling energy balance. Liver X receptors (LXRs) and... 
METABOLIC SYNDROME | STEAROYL-COA DESATURASE | PARAVENTRICULAR NUCLEUS | MESSENGER-RNA | ALZHEIMERS-DISEASE | TRH TRANSCRIPTION | ACID-METABOLISM | MULTIDISCIPLINARY SCIENCES | IN-VIVO | PROTEIN GENE-EXPRESSION | LIPOPROTEIN-LIPASE | Orphan Nuclear Receptors - metabolism | Orphan Nuclear Receptors - genetics | Pregnancy | Thyrotropin-Releasing Hormone - metabolism | Animals | Hypothalamus - metabolism | Thyrotropin-Releasing Hormone - genetics | Chromatin Immunoprecipitation | Liver X Receptors | Protein Binding | Female | Mice | Thyroid Gland - metabolism | Brain | Regulators | Disease | Liver | Crosstalk | Thyroid gland | Signal transduction | Receptors | Thyroid | Obesity | Cytokines | Thyroid hormone receptors | Hypothyroidism | Gene expression | Retinoid X receptors | Metabolism | Energy balance | Thyroid-stimulating hormone | Molecular modelling | Metabolic disorders | Chromatin | Immunoprecipitation | Transcription | Genes | Gene regulation | Reversing | Homeostasis | Hypothalamus | Kinases | Autophagy | Pathways | Metabolites | Rodents | Atherosclerosis | Triiodothyronine | Thyroid hormones | Gene transfer | Liver X receptors | Thyrotropin-releasing hormone | Melanocortin | Melanocortin MC4 receptors | Inflammation | Cholesterol | Signaling | Hypothalamic-pituitary-thyroid axis | Pituitary | Diabetes | Laboratory animals
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2014, Volume 9, Issue 9, p. e106289
Pancreatic ductal adenocarcinoma (PDAC) is difficult to detect early and is often resistant to standard chemotherapeutic options, contributing to extremely... 
BREAST-CANCER | TRIAL | GROWTH-FACTOR RECEPTOR | THERAPY | INHIBITION | MULTIDISCIPLINARY SCIENCES | PROSTATE-CANCER CELLS | DEGRADATION | PROLIFERATION | MICE | GEMCITABINE | Adenocarcinoma - pathology | Pancreatic Neoplasms - metabolism | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Deoxycytidine - pharmacology | Male | Gene Expression Profiling | Neoplasm Proteins - metabolism | Orphan Nuclear Receptors - metabolism | Pancreatic Neoplasms - drug therapy | Adenocarcinoma - metabolism | Microarray Analysis | Liver X Receptors | Adult | Female | Adenocarcinoma - genetics | Antineoplastic Agents - pharmacology | Neoplasm Proteins - genetics | Signal Transduction | Orphan Nuclear Receptors - agonists | Pancreatic Neoplasms - pathology | Pancreatic Neoplasms - genetics | Adenocarcinoma - drug therapy | Orphan Nuclear Receptors - genetics | Benzoates - pharmacology | Cell Line, Tumor | Ligands | Aged | Cell Proliferation - drug effects | Cell Cycle - drug effects | Benzylamines - pharmacology | Deoxycytidine - analogs & derivatives | Cell proliferation | Adenocarcinoma | Laboratories | Liver | Homeostasis | Biochemistry | Biology | Kinases | Cancer therapies | Proteins | Receptors | Rodents | Surgery | Cell cycle | Lipid metabolism | Pancreas | Medical research | Liver X receptors | Breast cancer | Metabolism | Gene expression | Nuclear receptors | Cholesterol | Biological activity | Medicine | Signaling | DNA microarrays | Diabetes | Prostate | Apoptosis | Bile
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 11/2014, Volume 124, Issue 11, pp. 4829 - 4842
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2012, Volume 7, Issue 9, p. e44998
textabstractMultiple sclerosis is a chronic, inflammatory, demyelinating disease of the central nervous system in which macrophages and microglia play a... 
TUMOR-NECROSIS-FACTOR | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | MULTIPLE-SCLEROSIS LESIONS | CELLULAR CHOLESTEROL | NUCLEAR RECEPTORS | MULTIDISCIPLINARY SCIENCES | EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS | CHOLESTEROL EFFLUX | CENTRAL-NERVOUS-SYSTEM | INTERACTING PROTEIN KINASE-2 | HIGH-DENSITY-LIPOPROTEINS | Oligonucleotide Array Sequence Analysis | Rats, Wistar | Humans | Hydrocarbons, Fluorinated - pharmacology | Cholesterol - immunology | Gene Expression Profiling | Phagocytosis - genetics | Lipid Metabolism - immunology | Orphan Nuclear Receptors - metabolism | Cell Movement - genetics | Cell Movement - physiology | Myelin Sheath - metabolism | Cell Movement - immunology | Liver X Receptors | Inflammation Mediators - metabolism | Orphan Nuclear Receptors - immunology | Lipid Metabolism - genetics | Interleukin-6 - metabolism | Macrophages, Peritoneal - drug effects | Multiple Sclerosis - metabolism | Inflammation Mediators - immunology | Interleukin-6 - genetics | Myelin Sheath - immunology | Cells, Cultured | Phagocytosis - immunology | Phagocytosis - physiology | Macrophages, Peritoneal - immunology | Rats | Multiple Sclerosis - genetics | Signal Transduction - genetics | Cholesterol - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Sulfonamides - pharmacology | Orphan Nuclear Receptors - genetics | Mice, Knockout | Animals | Signal Transduction - drug effects | Interleukin-6 - immunology | Multiple Sclerosis - immunology | Mice | Macrophages, Peritoneal - metabolism | Lipid Metabolism - physiology | Multiple sclerosis | Genes | Development and progression | Lipids | Inflammation | Genomes | Macrophages | Gene expression | Biomedical research | Liver | Central nervous system | Activation | Experiments | Interleukin 6 | Genotype & phenotype | Cell activation | Demyelination | Rodents | Life sciences | Lesions | Efflux | Phenotypes | Demyelinating diseases | Dendritic cells | Liver X receptors | Myelin | Metabolism | Cholesterol | Microglia | Signaling | Brain research | Internalization | Transnationalism | Receptor mechanisms | Phagocytosis
Journal Article
Journal Article
Journal Article