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Cancer Research, ISSN 0008-5472, 10/2018, Volume 78, Issue 19 Supplement, pp. IA04 - IA04
Journal Article
Cancer Research, ISSN 0008-5472, 07/2016, Volume 76, Issue 14 Supplement, pp. SY42-01 - SY42-01
Journal Article
Cancer Research, ISSN 0008-5472, 03/2016, Volume 76, Issue 5 Supplement, pp. IA28 - IA28
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 09/2015, Volume 21, Issue 17 Supplement, pp. IA23 - IA23
Journal Article
Cancer Research, ISSN 0008-5472, 10/2014, Volume 74, Issue 20 Supplement, pp. IA32 - IA32
Journal Article
Cancer Research, ISSN 0008-5472, 07/2012, Volume 72, Issue 13 Supplement, pp. IA18 - IA18
Journal Article
Frontiers in Oncology, ISSN 2234-943X, 2014, Volume 4, p. 170
Acute lymphoblastic leukemia is the most common malignancy in children. Although it is now curable in 80-90% of cases, patients with T-cell acute lymphoblastic... 
NOTCH1 | PI3K/AKT/mTOR | Bromodomain inhibitors | Cyclin-dependent kinases | Cyclins | BRD4 | PI3K pathway inhibitors | T-cell acute lymphoblastic leukemia | Cyclin-Dependent Kinases | targeted therapies
Journal Article
Nature, ISSN 0028-0836, 2013, Volume 499, Issue 7457, pp. 214 - 218
Journal Article
Nature Genetics, ISSN 1061-4036, 12/2017, Volume 49, Issue 12, pp. 1779 - 1784
Journal Article
Cancer Cell, ISSN 1535-6108, 07/2013, Volume 24, Issue 1, pp. 45 - 58
Journal Article
Nature Genetics, ISSN 1061-4036, 2014, Volume 46, Issue 4, pp. 364 - 370
The identification of activating NOTCH1 mutations in T cell acute lymphoblastic leukemia (T-ALL) led to clinical testing of g-secretase inhibitors (GSIs) that... 
NOTCH1 | INHIBITION | CHROMATIN | PATHWAY | GENES | GENETICS & HEREDITY | C-MYC | ACUTE MYELOID-LEUKEMIA | CANCER | LENTIVIRAL RNAI LIBRARY | GENOME | Chromatin - metabolism | Humans | Flow Cytometry | Chromatin Immunoprecipitation | Gene Expression Regulation, Neoplastic - drug effects | Indoles | Nuclear Proteins - genetics | Real-Time Polymerase Chain Reaction | Gene Expression Regulation, Neoplastic - genetics | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Enzyme-Linked Immunosorbent Assay | Nuclear Proteins - metabolism | Transcription Factors - antagonists & inhibitors | Signal Transduction - genetics | Transcription Factors - genetics | Enzyme Inhibitors - therapeutic use | Azepines - pharmacology | Transcription Factors - metabolism | Triazoles - pharmacology | Drug Resistance, Neoplasm - genetics | Animals | Epigenesis, Genetic - genetics | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - genetics | Nuclear Proteins - antagonists & inhibitors | Cell Line, Tumor | Mice | Amyloid Precursor Protein Secretases - antagonists & inhibitors | Histones - metabolism | Receptor, Notch1 - antagonists & inhibitors | Receptor, Notch1 - genetics | Chromatin - genetics | Care and treatment | Pharmacology, Experimental | Acute lymphocytic leukemia | Research | Drug resistance | Proteins | Genotype & phenotype | Leukemia | Epigenetics | Genomes | Kinases | Gene expression | Cancer therapies
Journal Article
by Michailidou, Kyriaki and Lindström, Sara and Dennis, Joe and Beesley, Jonathan and Hui, Shirley and Kar, Siddhartha and Lemaçon, Auey and Soucy, Penny and Glubb, Dylan and Rostamianfar, Asha and Bolla, Manjeet K and Wang, Qin and Tyrer, Jonathan and Dicks, Ed and Lee, Anew and Wang, Zhaoming and Allen, Jamie and Keeman, Renske and Eilber, Ursula and French, Juliet D and Qing Chen, Xiao and Fachal, Laura and McCue, Karen and McCart Reed, Amy E and Ghoussaini, Maya and Carroll, Jason S and Jiang, Xia and Finucane, Hilary and Adams, Marcia and Adank, Muriel A and Ahsan, Habibul and Aittomäki, Kristiina and Anton-Culver, Hoda and Antonenkova, Natalia N and Arndt, Volker and Aronson, Kristan J and Arun, Banu and Auer, Paul L and Bacot, François and Barrdahl, Myrto and Baynes, Caroline and Beckmann, Matthias W and Behrens, Sabine and Benitez, Javier and Bermisheva, Marina and Bernstein, Leslie and Blomqvist, Carl and Bogdanova, Natalia V and Bojesen, Stig E and Bonanni, Bernardo and Børresen-Dale, Anne-Lise and Brand, Judith S and Brauch, Hiltrud and Brennan, Paul and Brenner, Hermann and Brinton, Louise and Broberg, Per and Brock, Ian W and Broeks, Annegien and Brooks-Wilson, Angela and Brucker, Sara Y and Brüning, Thomas and Burwinkel, Barbara and Butterbach, Katja and Cai, Qiuyin and Cai, Hui and Caldés, Trinidad and Canzian, Federico and Carracedo, Angel and Carter, Brian D and Castelao, Jose E and Chan, Tsun L and David Cheng, Ting-Yuan and Seng Chia, Kee and Choi, Ji-Yeob and Christiansen, Hans and Clarke, Christine L and Collée, Margriet and Conroy, Don M and Cordina-Duverger, Emilie and Cornelissen, Sten and Cox, David G and Cox, Angela and Cross, Simon S and Cunningham, Julie M and Czene, Kamila and Daly, Mary B and Devilee, Peter and Doheny, Kimberly F and Dörk, Thilo and Dos-Santos-Silva, Isabel and Dumont, Martine and Durcan, Lorraine and Dwek, Miriam and Eccles, Diana M and Ekici, Arif B and Eliassen, A. Heather and Ellberg, Carolina and Elvira, Mingajeva and Engel, Christoph and ... and KConFab AOCS Investigators and ABCTB Investigators and NBCS Collaborators and ConFab/AOCS Investigators and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Ortopedi and Uppsala universitet and Institutionen för kirurgiska vetenskaper
Nature, ISSN 0028-0836, 2017, Volume 551, Issue 7678, pp. 92 - 94
Journal Article