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Cancer Research, ISSN 0008-5472, 09/2018, Volume 78, Issue 17, pp. 5038 - 5049
Regulatory T cells (Tregs) are critical mediators of immune suppression in established tumors, although little is known about their role in restraining immune... 
self antigen | BRAFV600E | cancer immune surveillance | regulatory T cell | autochthonous tumorigenesis
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 07/2001, Volume 7, Issue 7, pp. 1888 - 1893
Journal Article
Cancer research, 09/2018, Volume 78, Issue 17, p. 5038
Regulatory T cells (Treg) are critical mediators of immunosuppression in established tumors, although little is known about their role in restraining... 
Journal Article
Cancer Research, ISSN 0008-5472, 09/2018, Volume 78, Issue 17, pp. 5038 - 5049
Journal Article
Cancer Research, ISSN 0008-5472, 2017, Volume 77, Issue 7, pp. 1599 - 1610
Journal Article
Journal of immunology (Baltimore, Md. : 1950), ISSN 0022-1767, 2/2014, Volume 192, Issue 4, pp. 1433 - 1439
Vitiligo is a CD8 T cell-mediated autoimmune disease that has been shown to promote the longevity of memory T cell responses to melanoma. However mechanisms... 
Journal Article
Journal Article
Pigment Cell & Melanoma Research, ISSN 1755-1471, 05/2014, Volume 27, Issue 3, pp. 495 - 501
The BRAF V600E mutation, which approaches 50% in human melanomas, constitutively activates pERK and contributes to disease progression. The BRAF V600E... 
Cells | Melanoma | Vemurafenib | PLX4032 | cell culture | melanoma | Murine BRafV600E | pERK | B6 syngeneic mouse model
Journal Article
Cancer research, ISSN 0008-5472, 4/2017, Volume 77, Issue 7, pp. 1599 - 1610
Acquired resistance to BRAF V600E inhibitors (BRAFi) in melanoma remains a common clinical obstacle, as is the case for any targeted drug therapy that can be... 
vemurafenib | CCL2 | MDSC | regulatory T cell | PLX4720
Journal Article
OncoImmunology, ISSN 2162-4011, 02/2015, Volume 4, Issue 2, pp. 1 - 3
As BRAF V600E -inhibitors become standard treatment for many metastatic melanoma patients, research has begun to elucidate their impact on the tumor immune... 
regulatory T cells | T | reg | MDSC, myeloid-derived suppressor cell | melanoma | BRAF | regulatory T cell | myeloid-derived suppressor cells | CD8 T cells | TME, tumor microenvironment | Regulatory T cells | Myeloid-derived suppressor cells | Melanoma | METASTATIC MELANOMA | ONCOLOGY | IMMUNOLOGY | VEMURAFENIB
Journal Article
Pigment Cell & Melanoma Research, ISSN 1755-1471, 05/2014, Volume 27, Issue 3, pp. 495 - 501
Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 05/2011, Volume 121, Issue 5, p. 1797
  A link between autoimmunity and improved antitumor immunity has long been recognized, although the exact mechanistic relationship between these two phenomena... 
Journal Article
by Yu, Jeannette J and Agrón, Elvira and Clemons, Traci E and Domalpally, Amitha and van Asten, Freekje and Keenan, Tiarnan D and Cukras, Catherine and Chew, Emily Y and Ferris, Frederick L and SanGiovanni, John Paul and Clemons, Traci and Lindblad, Anne and Lindblad, Robert and Shah, Nilay and Sperduto, Robert and McBee, Wendy and Gensler, Gary and Harrington, Molly and Henning, Alice and Jones, Katrina and Thotapally, Kumar and Tull, Diana and Watson, Valerie and Williams, Kayla and Gentry, Christina and Kaufman, Francine and Morrison, Chris and Saverino, Elizabeth and Schenning, Sherrie and Blodi, Barbara and Danis, Ronald P and Davis, Matthew and Glander, Kathy and Guilfoil, Gregory and Hubbard, Larry D and Johnson, Kristine and Klein, Ronald and Nardi, Barbara and Neider, Michael and Robinson, Nancy and Rosensteel, Eileen and Wabers, Hugh and Zhang, Grace and Ruby, Alan J and Capone, Antonio and Dass, Bawa and Drenser, Kimberly and Garretson, Bruce R and Hassan, Tarek S and Trese, Michael and Williams, George A and Wolfe, Jeremy and Bell, Tina and Zajechowski, Mary and Bezaire, Dennis and McIver, Fran and Medina, Anthony and Pagett, Jackie and Smith, Stephanie Hatch and Swartz, Lynn and Treuter, Tom and Antoszyk, Andrew and Brown, Justin and Browning, David J and Holland, Walter and Karow, Angella and Stalford, Kelly and Price, Angela and Ennis, Sarah and Fredenberg, Sherry and Herby, Jenna and Balasubramaniam, Uma and Clark, Loraine and McClain, Donna and McOwen, Michael and Watson, Lynn and Klein, Michael and Bailey, Steven T and Hwang, Thomas J and Lauer, Andreas and Stout, J. Timothy and McCollum, Patty and Johnson, Milt and Rice, Patrick B and Kim, Ivana and Loewenstein, John and Miller, Joan and Sobrin, Lucia and Young, Lucy and Sullivan, Jacqueline and Houlihan, Patricia and Merry, Linda and Lane, Ann Marie and Bator, Ursula Lord and Evans, Claudia and Brett, Sarah and Callahan, Charleen and Grillo, Marcia and Walsh, David and Zimmerman, Kamella Lau and ... and Age Related Eye Dis Study 2 Res and Age-Related Eye Disease Study 2 Research Group
Ophthalmology, ISSN 0161-6420, 02/2019, Volume 126, Issue 2, pp. 261 - 273
Purpose: To investigate the natural history and genetic associations of drusenoid pigment epithelial detachment (DPED) associated with age-related macular... 
ARMS2 | EYE DISEASE | EVOLUTION | OPHTHALMOLOGY | CLASSIFICATION | RISK | POLYMORPHISM | VARIANT | GEOGRAPHIC ATROPHY
Journal Article