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Journal of Structural Biology, ISSN 1047-8477, 04/2018, Volume 202, Issue 1, pp. 13 - 24
Rho family GTPases regulate a wide range of cellular processes. This includes cellular dynamics where three subfamilies, Rho, Rac, and Cdc42, are known to... 
Membrane localization | RhoGEF | GTPase | Crosstalk | PH domain | Crystal structure | LOCALIZATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | LARG | GEFS | BINDING PROTEIN | IDENTIFICATION | ULTRACENTRIFUGATION | CELL BIOLOGY | BIOPHYSICS | PLECKSTRIN HOMOLOGY DOMAIN | PDZ-RHOGEF | FOCAL ADHESION KINASE | NUCLEOTIDE-EXCHANGE FACTORS
Journal Article
2007, 1st ed., Advances in protein chemistry, ISBN 9780120342884, Volume 74., x, 253 p., [26] p. of plates
This volume in the Advances in Protein Chemistry series features cutting-edge articles on topics in protein chemistry. This volume includes chapters on the... 
Cellular signal transduction | G proteins
Book
Science, ISSN 0036-8075, 06/1998, Volume 280, Issue 5372, pp. 2109 - 2111
Journal Article
Science, ISSN 0036-8075, 06/1998, Volume 280, Issue 5372, pp. 2112 - 2114
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2015, Volume 112, Issue 48, pp. 14852 - 14857
Journal Article
Data in Brief, ISSN 2352-3409, 04/2018, Volume 17, pp. 356 - 362
The Pleckstrin homology (PH) domains from the Lbc family of Rho Guanine Nucleotide Exchange Factors (Lbc RhoGEFs) interact with activated Rho family GTPases.... 
Journal Article
Molecular Pharmacology, ISSN 0026-895X, 03/2013, Volume 83, Issue 3, pp. 587 - 593
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 1993, Volume 268, Issue 13, pp. 9667 - 9674
Journal Article
STRUCTURE, ISSN 0969-2126, 10/2008, Volume 16, Issue 10, pp. 1532 - 1543
G12 class heterotrimeric G proteins stimulate RhoA activation by RGS-RhoGEFs. However, p115RhoGEF is a GTPase Activating Protein (GAP) toward Gal 3, whereas... 
COMPLEX | HETEROTRIMERIC G-PROTEINS | P115 RHOGEF | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSITION-STATE | GTP-BINDING PROTEINS | RGS PROTEINS | STRUCTURAL DETERMINANTS | CELL BIOLOGY | BIOPHYSICS | G-ALPHA SUBUNITS | EXCHANGE FACTORS
Journal Article
J. Biol. Chem, ISSN 0021-9258, 09/2012, Volume 287, Issue (30) ; 06, 2012
RGS-containing RhoGEFs (RGS-RhoGEFs) represent a direct link between the G{sub 12} class of heterotrimeric G proteins and the monomeric GTPases. In addition to... 
TRYPTOPHAN | MUTAGENESIS | STIMULATION | BASIC BIOLOGICAL SCIENCES | 60 APPLIED LIFE SCIENCES | GTP-ASES | NUCLEOTIDES | BIOCHEMISTRY | GUANINE | MUTATIONS | REGULATIONS | PROTEINS | RESIDUES | SCATTERING
Journal Article
Nature Cell Biology, ISSN 1465-7392, 06/2006, Volume 8, Issue 6, pp. 571 - 580
Journal Article
Protein Science, ISSN 0961-8368, 01/2011, Volume 20, Issue 1, pp. 107 - 117
Journal Article
Science Signaling, ISSN 1945-0877, 06/2009, Volume 2, Issue 75, pp. ra28 - ra28
The activation of macrophages through Toll-like receptor (TLR) pathways leads to the production of a broad array of cytokines and mediators that coordinate the... 
PROTEIN-KINASE-A | RNA INTERFERENCE | CYCLIC-AMP | VASOACTIVE-INTESTINAL-PEPTIDE | NECROSIS-FACTOR-ALPHA | NF-KAPPA-B | SIGNALING COMPLEXES | ANCHORING PROTEIN | MONOCYTIC CELLS | INNATE IMMUNITY | CELL BIOLOGY | Tumor Necrosis Factor-alpha - genetics | NF-kappa B p50 Subunit - genetics | Dinoprostone - immunology | NF-kappa B p50 Subunit - immunology | A Kinase Anchor Proteins - genetics | Inflammation - metabolism | Cyclic AMP-Dependent Protein Kinases - genetics | RNA Interference | Tumor Necrosis Factor-alpha - immunology | Cyclic AMP - genetics | Phosphorylation - immunology | Phosphorylation - drug effects | Cyclic AMP - metabolism | A Kinase Anchor Proteins - metabolism | Macrophages - immunology | Cyclic AMP-Dependent Protein Kinases - metabolism | Cell Line | Second Messenger Systems - drug effects | NF-kappa B p50 Subunit - metabolism | Dinoprostone - genetics | Gene Expression Regulation - immunology | Toll-Like Receptor 4 - genetics | Inflammation - immunology | Toll-Like Receptor 4 - immunology | Second Messenger Systems - immunology | Toll-Like Receptor 4 - metabolism | Dinoprostone - metabolism | Gene Expression Regulation - drug effects | Macrophages - metabolism | Animals | A Kinase Anchor Proteins - immunology | Cyclic AMP-Dependent Protein Kinases - immunology | Cyclic AMP - immunology | Lipopolysaccharides - pharmacology | Inflammation - genetics | Mice | Tumor Necrosis Factor-alpha - biosynthesis | Index Medicus
Journal Article
Journal Article
Structure, ISSN 0969-2126, 10/2008, Volume 16, Issue 10, p. 1532
G12 class heterotrimeric G proteins stimulate RhoA activation by RGS-RhoGEFs. However, p115RhoGEF is a GTPase Activating Protein (GAP) toward G[alpha]13,... 
G proteins | Structure | Gross domestic product | Crystals | Membrane proteins
Journal Article
Journal Article
The Journal of biological chemistry, ISSN 0021-9258, 06/2008, Volume 283, Issue 25, pp. 17351 - 17361
Studies in fibroblasts, neurons, and platelets have demonstrated the integration of signals from different G protein-coupled receptors (GPCRs) in raising... 
Phospholipase C beta - metabolism | Signal Transduction | Calcium - metabolism | Humans | Complement C5a - chemistry | Pinocytosis | Phosphatidylinositol 3-Kinases - metabolism | Uridine Diphosphate - chemistry | Macrophages - metabolism | Animals | Models, Biological | Protein Isoforms | Ligands | Mice | Kinetics | Index Medicus
Journal Article
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