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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2011, Volume 108, Issue 31, pp. 12669 - 12674
Journal Article
Journal Article
Acta Crystallographica Section D, ISSN 1399-0047, 06/2013, Volume 69, Issue 6, pp. 1124 - 1137
Journal Article
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 06/2003, Volume 42, Issue 22, pp. 2507 - 2511
A highly fluorophilic environment comprising the HCαCO unit of Asn 98 in the active site of thrombin was identified by X‐ray crystallography of a complex... 
inhibitors | molecular recognition | thrombin | structure elucidation | medicinal chemistry | fluorine | Molecular recognition | Thrombin | Medicinal chemistry | Inhibitors | Fluorine | Structure elucidation
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 07/2005, Volume 44, Issue 28, pp. 4400 - 4404
The aromatic box formed by the side chains Phe 174, Tyr 99, and Trp 215 in the S4‐pocket of Factor Xa is a very effective onium binding site (see picture; red... 
cation–pi interactions | inhibitors | Factor Xa | molecular recognition | thrombin | Molecular recognition | Cation-pi interactions | Thrombin | Inhibitors
Journal Article
Journal Article