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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2011, Volume 108, Issue 11, pp. 4400 - 4405
Ozonide OZ439 is a synthetic peroxide antimalarial drug candidate designed to provide a single-dose oral cure in humans. OZ439 has successfully completed Phase... 
Artemisinins | Malaria | Half lives | Antimalarials | Peroxides | Parasites | Dosage | Ozonides | Blood | Blood plasma | 1,2,4-trioxolane | Antimalarial drug discovery | OZ277 | PHARMACODYNAMIC PROPERTIES | MULTIDISCIPLINARY SCIENCES | ARTEROLANE | TRIOXOLANE | 1-AMINOBENZOTRIAZOLE | antimalarial drug discovery | PEROXIDES | IN-VITRO ASSESSMENT | PLASMODIUM-FALCIPARUM | ANTIMALARIAL ACTIVITY | ARTEMISININ | Peroxides - administration & dosage | Plasmodium berghei - physiology | Male | Peroxides - therapeutic use | Peroxides - pharmacokinetics | Dose-Response Relationship, Drug | Artemisinins - pharmacology | Heterocyclic Compounds - chemistry | Time Factors | Adamantane - therapeutic use | Adamantane - administration & dosage | Adamantane - pharmacokinetics | Artemisinins - chemistry | Adamantane - analogs & derivatives | Antimalarials - pharmacokinetics | Heterocyclic Compounds - administration & dosage | Drug Stability | Peroxides - chemistry | Rats | Treatment Outcome | Antimalarials - therapeutic use | Iron - metabolism | Rats, Sprague-Dawley | Animals | Artemisinins - therapeutic use | Antimalarials - administration & dosage | Antimalarials - chemistry | Malaria - parasitology | Heterocyclic Compounds - pharmacokinetics | Mice | Adamantane - chemistry | Heterocyclic Compounds - therapeutic use | Malaria - drug therapy | Care and treatment | Composition | Health aspects | Malaria vaccine | Biological Sciences
Journal Article
Nuclear Inst. and Methods in Physics Research, A, ISSN 0168-9002, 04/2019, Volume 922, pp. 345 - 351
Macroparticle tracking is a prominent method for studying the collective beam instabilities in accelerators. However, the heavy computationalload often limits... 
Collective instabilities | GPU computing | PHYSICS, NUCLEAR | INSTRUMENTS & INSTRUMENTATION | NUCLEAR SCIENCE & TECHNOLOGY | PHYSICS, PARTICLES & FIELDS
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 12/2017, Volume 62, Issue 3
ABSTRACTThe peroxide bond of the artemisinins inspired the development of a class of fully synthetic 1,2,4-trioxolane-based antimalarials, collectively known... 
Journal Article
Nuclear Inst. and Methods in Physics Research, A, ISSN 0168-9002, 03/2019, Volume 920, pp. 106 - 114
Radio frequency (RF) cavities are commonly used to accelerate charged particle beams. The shape of the RF cavity determines the resonant electromagnetic fields... 
Multi-objective optimization | RF cavity design | Evolutionary algorithm | Higher order modes | INSTRUMENTS & INSTRUMENTATION | OPTIMAL-DESIGN | NUCLEAR SCIENCE & TECHNOLOGY | PHYSICS, NUCLEAR | PHYSICS, PARTICLES & FIELDS | Physics - Accelerator Physics
Journal Article
Nuclear Inst. and Methods in Physics Research, A, ISSN 0168-9002, 08/2016, Volume 828, pp. 156 - 162
The Flat Top Cavity, located in the PSI HIPA Ring Cyclotron leaks RF power of several kilo Watts into the cyclotron's vacuum space causing several... 
Multi-physics | RF cavity | Cyclotron | Simulation | Flat Top | Analysis | Particle accelerators | Radiation | Physics - Accelerator Physics
Journal Article
by Milne, Christopher J and Schietinger, Thomas and Aiba, Masamitsu and Alarcon, Arturo and Alex, Jürgen and Anghel, Alexander and Arsov, Vladimir and Beard, Carl and Beaud, Paul and Bettoni, Simona and Bopp, Markus and Brands, Helge and Brönnimann, Manuel and Brunnenkant, Ingo and Calvi, Marco and Citterio, Alessandro and Craievich, Paolo and Divall, Marta Csatari and Dällenbach, Mark and D'Amico, Michael and Dax, Andreas and Deng, Yunpei and Dietrich, Alexander and Dinapoli, Roberto and Divall, Edwin and Dordevic, Sladana and Ebner, Simon and Erny, Christian and Fitze, Hansrudolf and Flechsig, Uwe and Follath, Rolf and Frei, Franziska and Gärtner, Florian and Ganter, Romain and Garvey, Terence and Geng, Zheqiao and Gorgisyan, Ishkhan and Gough, Christopher and Hauff, Andreas and Hauri, Christoph P and Hiller, Nicole and Humar, Tadej and Hunziker, Stephan and Ingold, Gerhard and Ischebeck, Rasmus and Janousch, Markus and Juranić, Pavle and Jurcevic, Mario and Kaiser, Maik and Kalantari, Babak and Kalt, Roger and Keil, Boris and Kittel, Christoph and Knopp, Gregor and Koprek, Waldemar and Lemke, Henrik T and Lippuner, Thomas and Sancho, Daniel Llorente and Löhl, Florian and Lopez-Cuenca, Carlos and Märki, Fabian and Marcellini, Fabio and Marinkovic, Goran and Martiel, Isabelle and Menzel, Ralf and Mozzanica, Aldo and Nass, Karol and Orlandi, Gian Luca and Loch, Cigdem Ozkan and Panepucci, Ezequiel and Paraliev, Martin and Patterson, Bruce and Pedrini, Bill and Pedrozzi, Marco and Pollet, Patrick and Pradervand, Claude and Prat, Eduard and Radi, Peter and Raguin, Jean-Yves and Redford, Sophie and Rehanek, Jens and Réhault, Julien and Reiche, Sven and Ringele, Matthias and Rittmann, Jochen and Rivkin, Leonid and Romann, Albert and Ruat, Marie and Ruder, Christian and Sala, Leonardo and Schebacher, Lionel and Schilcher, Thomas and Schlott, Volker and Schmidt, Thomas and Schmitt, Bernd and Shi, Xintian and Stadler, Markus and Stingelin, Lukas and Sturzenegger, Werner and Szlachetko, Jakub and ...
Applied Sciences (Switzerland), ISSN 2076-3417, 07/2017, Volume 7, Issue 7, p. 720
Journal Article
Nuclear Inst. and Methods in Physics Research, A, ISSN 0168-9002, 06/2016, Volume 821, pp. 87 - 92
A plasma has been observed inside the vacuum chamber of the PSI Ring Cyclotron. This ionized gas cloud may be a substantial contributor to several interior... 
RF cavity | Plasma | Spectroscopy | Cyclotron design | Flat Top | INSTRUMENTS & INSTRUMENTATION | NUCLEAR SCIENCE & TECHNOLOGY | PHYSICS, NUCLEAR | PHYSICS, PARTICLES & FIELDS | Analysis | Electronic cameras | Particle accelerators | Electric potential | Clouds | Flats | Spectrometers | Voltage | Holes | Plasma (physics) | Cyclotrons | Physics - Accelerator Physics
Journal Article
Nuclear Inst. and Methods in Physics Research, A, ISSN 0168-9002, 2011, Volume 637, Issue 1, pp. 12 - 17
A novel eddy current based focusing solenoid concept was developed, in which the eddy currents are used to generate the main focusing field rather than... 
Focusing magnet | Eddy currents | Pulsed solenoid | INSTRUMENTS & INSTRUMENTATION | SPECTROSCOPY | NUCLEAR SCIENCE & TECHNOLOGY | PHYSICS, PARTICLES & FIELDS | Accelerators | Computer simulation | Coiling | Focusing | Segments | Mathematical models | Solenoids | Cylinders
Journal Article
Proceedings of the National Academy of Sciences, USA, ISSN 0027-8424, 03/2011, Volume 108, Issue 11, pp. 4400 - 4405
Ozonide OZ439 is a synthetic peroxide antimalarial drug candidate designed to provide a single-dose oral cure in humans. OZ439 has successfully completed Phase... 
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 03/2011, Volume 108, Issue 11, p. 4400
Ozonide OZ439 is a synthetic peroxide antimalarial drug candidate designed to provide a single-dose oral cure in humans. OZ439 has successfully completed Phase... 
Drugs | Malaria | Erythrocytes | Clinical trials | Parasitic protozoa | Blood
Journal Article
09/2018
Macro-particle tracking is a prominent method to study the collective beam instabilities in accelerators. However, the heavy computation load often limits the... 
Physics - Accelerator Physics
Journal Article
Physical Review Accelerators and Beams, ISSN 2469-9888, 06/2018, Volume 21, Issue 6, p. 064701
For an optimal exploitation of the benefits of proton therapy the most accurate dose delivery system should be used. The TERA Foundation has extensive... 
TESTS | PROTONTHERAPY | LIBO | PHYSICS, NUCLEAR | PHYSICS, PARTICLES & FIELDS
Journal Article
Physical Review Accelerators and Beams, ISSN 2469-9888, 07/2016, Volume 19, Issue 7, p. 072001
The design of a photoinjector, in particular that of the electron source, is of central importance for free electron laser (FEL) machines where a high beam... 
PHYSICS, NUCLEAR | PHYSICS, PARTICLES & FIELDS
Journal Article
IPAC 2016 - Proceedings of the 7th International Particle Accelerator Conference, 2016, pp. 1678 - 1681
Conference Proceeding
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