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Lancet Oncology, The, ISSN 1470-2045, 2014, Volume 15, Issue 10, pp. 1065 - 1075
Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2016, Volume 17, Issue 10, pp. 1426 - 1434
Journal Article
Journal Article
Journal Article
International Journal of Cancer, ISSN 0020-7136, 09/2017, Volume 141, Issue 6, pp. 1222 - 1230
The TLR7 and TLR9 signalings are implicated in the regulation of the immune system through type‐I interferon induction. Preclinical studies have demonstrated... 
cetuximab | metastatic colorectal cancer | polymorphism | TLR7 | predictive marker | SYSTEMIC-LUPUS-ERYTHEMATOSUS | ANTIBODY | IFN-ALPHA PRODUCTION | RECEPTOR 7 | PLASMACYTOID DENDRITIC CELLS | SEX-SPECIFIC ASSOCIATION | IMMUNE | THERAPY | ONCOLOGY | INFLAMMATION | INDEPENDENTLY CONTRIBUTE | Leucovorin - administration & dosage | Predictive Value of Tests | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Colorectal Neoplasms - genetics | Humans | Middle Aged | Male | RNA, Messenger - biosynthesis | Clinical Trials, Phase III as Topic | Neoplasm Metastasis | Fluorouracil - administration & dosage | Multicenter Studies as Topic | Colorectal Neoplasms - drug therapy | Camptothecin - administration & dosage | Female | Camptothecin - analogs & derivatives | Toll-Like Receptor 7 - genetics | Toll-Like Receptor 7 - biosynthesis | RNA, Messenger - genetics | Randomized Controlled Trials as Topic | Disease-Free Survival | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Cetuximab - administration & dosage | Aged | Polymorphism, Single Nucleotide | Colorectal Neoplasms - pathology | Clinical Trials, Phase II as Topic | Cancer patients | Care and treatment | Chemotherapy | Analysis | Colorectal cancer | Genetic aspects | Interferon | Single nucleotide polymorphisms | Metastasis | Biological response modifiers | Chromosomes | Cancer | Colorectal carcinoma | Single-nucleotide polymorphism | K-Ras protein | Bevacizumab | Metastases | Gene sequencing | Anticancer properties | Toll-like receptors | Deoxyribonucleic acid--DNA | Immune system | Killing | TLR7 protein | Immunomodulation | Genetic diversity | Patients | TLR9 protein | Polymerase chain reaction | Interferon regulatory factor 7 | Studies | Antitumor activity | Death | DNA sequencing | Polymorphism
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2018, Volume 13, Issue 3, p. e0193640
Journal Article
International Journal of Cancer, ISSN 0020-7136, 07/2017, Volume 141, Issue 2, pp. 383 - 392
The Insulin‐like growth factor (IGF)/IGF‐receptor pathway with its scaffolding proteins Insulin Receptor Substrate (IRS)1 and IRS2 are crucial regulators of... 
metastatic colorectal cancer | IGF | IRS | SNP | RAS | PHASE-II | MONOCLONAL-ANTIBODY | METASTATIC COLORECTAL-CANCER | INSULIN-RECEPTORS | POSITIVE BREAST-CANCER | CELL LUNG-CANCER | GROWTH-FACTOR RECEPTOR | CETUXIMAB | ONCOLOGY | FACTOR-I RECEPTOR | TYPE-2 DIABETES-MELLITUS | Bevacizumab - therapeutic use | Prognosis | Camptothecin - therapeutic use | Signal Transduction | Colorectal Neoplasms - genetics | Humans | Genetic Association Studies - methods | Male | Cetuximab - therapeutic use | Sequence Analysis, DNA | Fluorouracil - therapeutic use | Neoplasm Metastasis | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Colorectal Neoplasms - drug therapy | Somatomedins - genetics | Survival Analysis | Female | Leucovorin - therapeutic use | Polymorphism, Single Nucleotide | Insulin Receptor Substrate Proteins - genetics | Camptothecin - analogs & derivatives | Proteins | Medical research | Analysis | Patient outcomes | Colorectal cancer | Physiological aspects | Medicine, Experimental | Genetic aspects | Single nucleotide polymorphisms | Metastasis | Chromosomes | Drugs | Regulators | Insulin-like growth factor I | Tumor cells | Test procedures | Genes | Colorectal carcinoma | Markers | Ras protein | Insulin-like growth factors | Single-nucleotide polymorphism | Metabolism | Insulin | Survival | Patients | Metastases | Carriers | Polymerase chain reaction | Signal transduction | Scaffolding | Cancer
Journal Article
by Jiang, Xia and Jiang, Xia and Finucane, Hilary K and Finucane, Hilary K and Schumacher, Fredrick R and Schumacher, Fredrick R and Schmit, Stephanie L and Tyrer, Jonathan P and Tyrer, Jonathan P and Han, Younghun and Han, Younghun and Michailidou, Kyriaki and Michailidou, Kyriaki and Lesseur, Corina and Kuchenbaecker, Karoline B and Kuchenbaecker, Karoline B and Dennis, Joe and Conti, David V and Casey, Graham and Gaudet, Mia M and Huyghe, Jeroen R and Albanes, Demetrius and Aldrich, Melinda C and Aldrich, Melinda C and Andrew, Angeline S and Andrew, Angeline S and Andrulis, Irene L and Anton-Culver, Hoda and Anton-Culver, Hoda and Antoniou, Antonis C and Antoniou, Antonis C and Antonenkova, Natalia N and Antonenkova, Natalia N and Arnold, Susanne M and Aronson, Kristan J and Aronson, Kristan J and Arun, Banu K and Arun, Banu K and Bandera, Elisa V and Bandera, Elisa V and Barkardottir, Rosa B and Barnes, Daniel R and Batra, Jyotsna and Beckmann, Matthias W and Benitez, Javier and Benitez, Javier and Benlloch, Sara and Benlloch, Sara and Berchuck, Andrew and Berchuck, Andrew and Berndt, Sonja I and Bickeböller, Heike and Bien, Stephanie A and Bien, Stephanie A and Blomqvist, Carl and Blomqvist, Carl and Boccia, Stefania and Bogdanova, Natalia V and Bogdanova, Natalia V and Bojesen, Stig E and Bolla, Manjeet K and Bolla, Manjeet K and Brauch, Hiltrud and Brenner, Hermann and Brenton, James D and Brenton, James D and Brook, Mark N and Brook, Mark N and Brunet, Joan and Brunet, Joan and Brunnström, Hans and Buchanan, Daniel D and Buchanan, Daniel D and Burwinkel, Barbara and Burwinkel, Barbara and Butzow, Ralf and Cadoni, Gabriella and Caldés, Trinidad and Caldés, Trinidad and Caligo, Maria A and Caligo, Maria A and Campbell, Ian and Campbell, Ian and Campbell, Peter T and Cancel-Tassin, Géraldine and Cancel-Tassin, Géraldine and Cannon-Albright, Lisa and Cannon-Albright, Lisa and Campa, Daniele and Campa, Daniele and Caporaso, Neil and Carvalho, André L and Carvalho, André L and Chan, Andrew T and Chan, Andrew T and Chang-Claude, Jenny and Chang-Claude, Jenny and Chanock, Stephen J and Chanock, Stephen J and Chen, Chu and ...
Nature Communications, ISSN 2041-1723, 01/2019, Volume 10, Issue 1, pp. 431 - 23
Quantifying the genetic correlation between cancers can provide important insights into the mechanisms driving cancer etiology. Using genome-wide association... 
BREAST-CANCER | LUNG-CANCER | RISK-FACTORS | PARTITIONING HERITABILITY | MULTIDISCIPLINARY SCIENCES | SUSCEPTIBILITY LOCI | GENETIC ARCHITECTURE | ANALYSES IDENTIFY | MENDELIAN RANDOMIZATION | CELL-TYPES | GENOME-WIDE ASSOCIATION | Lung Neoplasms - ethnology | Colorectal Neoplasms - genetics | Humans | Ovarian Neoplasms - pathology | Lung Neoplasms - pathology | Male | Prostatic Neoplasms - diagnosis | Case-Control Studies | Colorectal Neoplasms - diagnosis | Ovarian Neoplasms - ethnology | Inheritance Patterns | Ovarian Neoplasms - genetics | Mental Disorders - genetics | Prostatic Neoplasms - genetics | Smoking - physiopathology | Head and Neck Neoplasms - ethnology | Female | Neoplasm Proteins - genetics | Breast Neoplasms - ethnology | Lung Neoplasms - genetics | Prostatic Neoplasms - pathology | Genetic Predisposition to Disease | Genome-Wide Association Study | Colorectal Neoplasms - ethnology | Ovarian Neoplasms - diagnosis | European Continental Ancestry Group | Smoking - genetics | Prostatic Neoplasms - ethnology | Head and Neck Neoplasms - pathology | Mental Disorders - physiopathology | Smoking - ethnology | Phenotype | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Head and Neck Neoplasms - diagnosis | Head and Neck Neoplasms - genetics | Breast Neoplasms - diagnosis | Mental Disorders - ethnology | Polymorphism, Single Nucleotide | Colorectal Neoplasms - pathology | Lung Neoplasms - diagnosis | Enrichment | Correlation | Statistical analysis | Ovarian carcinoma | Mental disorders | Lung cancer | Colorectal carcinoma | Genomes | Breast cancer | Regulatory sequences | Ovarian cancer | Etiology | Breast | Heritability | Neck | Solid tumors | Prostate cancer | Prostate | Cancer | Smoking
Journal Article