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Microvascular Research, ISSN 0026-2862, 2009, Volume 77, Issue 2, pp. 78 - 86
Lenalidomide (Revlimid®) is approved for the treatment of transfusion-dependent patients with anemia due to low- or intermediate-1-risk Myelodysplastic... 
Angiogenesis | Lenalidomide | HIF-1α | Metastasis | Akt | Cadherin | IMiDs | MIGRATION | HIF-1 alpha | PHOSPHORYLATION | IMiDs (R) | THALIDOMIDE | CANCER | IN-VITRO | THERAPY | PATHWAY | PERIPHERAL VASCULAR DISEASE | TUMOR-GROWTH | PROGRESSION | Cadherins - metabolism | Humans | Melanoma, Experimental - drug therapy | Thalidomide - pharmacology | Microcirculation - drug effects | Antigens, CD - metabolism | Cell Hypoxia | Thalidomide - analogs & derivatives | Basic Helix-Loop-Helix Transcription Factors - metabolism | Lung Neoplasms - secondary | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Neoplasm Metastasis - prevention & control | Platelet Endothelial Cell Adhesion Molecule-1 - metabolism | Female | Neovascularization, Pathologic - prevention & control | Antineoplastic Agents - pharmacology | Proto-Oncogene Proteins c-akt - metabolism | Cells, Cultured | Angiogenesis Inhibitors - pharmacology | beta Catenin - metabolism | Pregnancy | Umbilical Arteries - growth & development | Animals | Lung Neoplasms - prevention & control | Umbilical Arteries - drug effects | Cell Differentiation - drug effects | Adherens Junctions - drug effects | Cell Line, Tumor | Mice | Endothelial Cells - pathology | In Vitro Techniques | Endothelial Cells - drug effects | Care and treatment | Dexamethasone | Analysis | Multiple myeloma | Dimethyl sulfoxide | Melanoma | Fibroblast growth factors | Angiogenesis inhibitors | Vascular endothelial growth factor | Endothelium | Cancer | Index Medicus
Journal Article
Journal of Immunology, ISSN 0022-1767, 07/1999, Volume 163, Issue 1, pp. 380 - 386
Journal Article
Journal Article
Leukemia Research, ISSN 0145-2126, 2006, Volume 30, Issue 7, pp. 849 - 858
Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 06/2003, Volume 305, Issue 3, pp. 1222 - 1232
Journal Article
The Journal of Immunology, ISSN 0022-1767, 05/2002, Volume 168, Issue 10, pp. 4914 - 4919
Thalidomide and its novel T cell costimulatory analogs (immunomodulatory drugs) are currently being assessed in the treatment of patients with advanced cancer.... 
MULTIPLE-MYELOMA | IN-VITRO | CYTOKINE PRODUCTION | INTERFERON-GAMMA | ANGIOGENESIS | IFN-GAMMA | IMMUNOLOGY | TNF-ALPHA PRODUCTION | POTENT INHIBITORS | CANCER VACCINES | T-CELLS | T-Lymphocyte Subsets - immunology | Adjuvants, Immunologic - administration & dosage | Spleen - immunology | Antigens, CD - biosynthesis | Coculture Techniques | Membrane Glycoproteins - biosynthesis | Tumor Cells, Cultured - transplantation | Neoplasm Transplantation - immunology | Th1 Cells - immunology | Tumor Cells, Cultured - pathology | B7-2 Antigen | Thalidomide - analogs & derivatives | Melanoma, Experimental | Injections, Subcutaneous | Histocompatibility Antigens Class I - biosynthesis | B7-1 Antigen - biosynthesis | Tumor Cells, Cultured - immunology | Cancer Vaccines - administration & dosage | Mice, Inbred C57BL | Cells, Cultured | Injections, Intraperitoneal | Tumor Cells, Cultured - metabolism | Spleen - cytology | Thalidomide - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - immunology | Cancer Vaccines - immunology | Growth Inhibitors - immunology | Animals | Growth Inhibitors - administration & dosage | Spleen - metabolism | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Mice, Nude | Mice | Mice, Inbred BALB C | Cytokines - biosynthesis | Interferon-gamma - biosynthesis | Index Medicus | Abridged Index Medicus
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 1999, Volume 9, Issue 11, pp. 1625 - 1630
Thalidomide, (1), is a known inhibitor of TNF-α release in LPS stimulated human PBMC. Herein we describe the TNF-α inhibitory activity of amino substituted... 
Thalidomide - analogs & derivatives | Thalidomide - chemical synthesis | Models, Chemical | U937 Cells | Humans | Blood - drug effects | Inhibitory Concentration 50 | Structure-Activity Relationship | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Index Medicus | AIDS/HIV
Journal Article
Seminars in Hematology, ISSN 0037-1963, 2000, Volume 37, Issue 1, pp. 5 - 14
Thalidomide is best known for its sedative, antiemetic, and teratogenic effects but also has diverse pharmacologic properties and therapeutic potential in... 
CYTOKINE PRODUCTION | BONE-MARROW | MONONUCLEAR-CELLS | NECROSIS-FACTOR-ALPHA | FIBROBLAST GROWTH-FACTOR | PERIPHERAL-BLOOD | INFECTED PATIENTS | TUMOR ANGIOGENESIS | HUMAN-IMMUNODEFICIENCY-VIRUS | HEMATOLOGY | VERSUS-HOST DISEASE
Journal Article
Journal Article
Cellular Immunology, ISSN 0008-8749, 2004, Volume 230, Issue 2, pp. 81 - 88
Immunomodulatory drugs (IMiDs) are potent inhibitors of TNF-α and IL-1β and elevators of IL-10 production in LPS-stimulated human PBMC. They are currently in... 
COX-2 | IMiDs | IL-10 | INDUCIBLE CYCLOOXYGENASE | LOW-DOSE THALIDOMIDE | MESSENGER-RNA STABILITY | IMMUNOLOGY | VERSUS-HOST-DISEASE | CELL BIOLOGY | COLON-CANCER CELLS | HEPATOCELLULAR-CARCINOMA | MEDIATED INDUCTION | CYTOKINE PRODUCTION | NF-KAPPA-B | PROSTAGLANDIN E-2
Journal Article