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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2014, Volume 111, Issue 38, pp. 13924 - 13929
Genetic variation can modulate gene expression, and thereby phenotypic variation and susceptibility to complex diseases such as type 2 diabetes (T2D). Here we... 
Beta cells | Databases | Allelic imbalance | Genes | Genetic loci | P values | Type 2 diabetes mellitus | Islets of Langerhans | Sequencing | Type 1 diabetes mellitus | PROVIDES INSIGHTS | VARIANTS | ALIGNMENT | RNA-SEQ | BETA-CELL TRANSCRIPTOME | MULTIDISCIPLINARY SCIENCES | INSULIN-SECRETION | GLYCEMIC TRAITS | DIABETES SUSCEPTIBILITY LOCI | EXPRESSION | ASSOCIATION | 5'-Nucleotidase - genetics | Cell Line | p21-Activated Kinases - genetics | Diabetes Mellitus, Type 2 - genetics | Genomics | Humans | Vesicular Transport Proteins - genetics | GPI-Linked Proteins - biosynthesis | Vesicular Transport Proteins - biosynthesis | Glucose - genetics | Male | RNA, Long Noncoding - genetics | Diabetes Mellitus, Type 2 - metabolism | Tetraspanins - biosynthesis | p21-Activated Kinases - biosynthesis | RNA, Long Noncoding - biosynthesis | Glucose - metabolism | Female | RNA Editing - physiology | Tetraspanins - genetics | Transcriptome - physiology | 5'-Nucleotidase - biosynthesis | GPI-Linked Proteins - genetics | Glucose metabolism | Pancreatic beta cells | Cell research | Genetic research | Genetic aspects | Genetic transcription | Research | Transcription factors | Pathogenesis | Glucose | Pancreas | Metabolism | Index Medicus | Biological Sciences | Clinical Medicine | Endokrinologi och diabetes | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap | Endocrinology and Diabetes
Journal Article
Diabetes, ISSN 0012-1797, 12/2017, Volume 66, Issue 12, pp. 3013 - 3028
Journal Article
The Lancet Diabetes & Endocrinology, ISSN 2213-8587, 05/2018, Volume 6, Issue 5, pp. 361 - 369
Journal Article
by Gaulton, Kyle J and Ferreira, Teresa and Lee, Yeji and Raimondo, Anne and Mägi, Reedik and Reschen, Michael E and Mahajan, Anubha and Locke, Adam and Rayner, N. William and Robertson, Neil and Scott, Robert A and Prokopenko, Inga and Scott, Laura J and Green, Todd and Sparso, Thomas and Thuillier, Dorothee and Yengo, Loic and Grallert, Harald and Wahl, Simone and Frånberg, Mattias and Strawbridge, Rona J and Kestler, Hans and Chheda, Himanshu and Eisele, Lewin and Gustafsson, Stefan and Steinthorsdottir, Valgerdur and Thorleifsson, Gudmar and Qi, Lu and Karssen, Lennart C and van Leeuwen, Elisabeth M and Willems, Sara M and Li, Man and Chen, Han and Fuchsberger, Christian and Kwan, Phoenix and Ma, Clement and Linderman, Michael and Lu, Yingchang and Thomsen, Soren K and Rundle, Jana K and Beer, Nicola L and van de Bunt, Martijn and Chalisey, Anil and Kang, Hyun Min and Voight, Benjamin F and Abecasis, Gonçalo R and Almgren, Peter and Baldassarre, Damiano and Balkau, Beverley and Benediktsson, Rafn and Blüher, Matthias and Boeing, Heiner and Bonnycastle, Lori L and Bottinger, Erwin P and Burtt, Noël P and Carey, Jason and Charpentier, Guillaume and Chines, Peter S and Cornelis, Marilyn C and Couper, David J and Crenshaw, Anew T and van Dam, Rob M and Doney, Alex S. F and Dorkhan, Mozhgan and Edkins, Sarah and Eriksson, Johan G and Esko, Tonu and Eury, Elodie and Fadista, João and Flannick, Jason and Fontanillas, Pierre and Fox, Caroline and Franks, Paul W and Gertow, Karl and Gieger, Christian and Gigante, Bruna and Gottesman, Omri and Grant, George B and Grarup, Niels and Groves, Christopher J and Hassinen, Maija and Have, Christian T and Herder, Christian and Holmen, Oddgeir L and Hreidarsson, Astradur B and Humphries, Steve E and Hunter, David J and Jackson, Anne U and Jonsson, Anna and Jørgensen, Marit E and Jørgensen, Torben and Kao, Wen-Hong L and Kerrison, Nicola D and Kinnunen, Leena and Klopp, Norman and Kong, Augustine and Kovacs, Peter and Kraft, Peter and Kravic, Jasmina and Langford, Cordelia and ... and DIAbet Genetics Replication Meta-A and the DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium and Numerisk analys och datalogi (NADA) and Naturvetenskapliga fakulteten and Stockholms universitet and Science for Life Laboratory (SciLifeLab)
Nature genetics, ISSN 1061-4036, 2015, Volume 47, Issue 12, pp. 1415 - +
Journal Article
Biochemical and biophysical research communications, ISSN 0006-291X, 09/2017, Volume 491, Issue 3, pp. 740 - 746
High blood glucose triggers the release of insulin from pancreatic beta cells, but if chronic, causes cellular stress, partly due to impaired Ca homeostasis.... 
Insulin-Secreting Cells - physiology | Cell Line | Lipoylation - physiology | Protein Subunits | Calcium - metabolism | Calcium Signaling - physiology | Rats | Ion Channel Gating - physiology | Animals | Protein Binding | Insulin-Secreting Cells - cytology | Apoptosis - physiology | Calcium Channels, L-Type - metabolism | Binding Sites
Journal Article
Gut, ISSN 0017-5749, 01/2014, Volume 63, Issue 1, pp. 131 - 142
Journal Article
Diabetes, ISSN 0012-1797, 04/2017, Volume 66, Issue 4, pp. 806 - 814
Journal Article
Diabetes Care, ISSN 0149-5992, 05/2016, Volume 39, Issue 5, pp. 794 - 800
Journal Article
Journal Article
Diabetologia, ISSN 0012-186X, 11/2015, Volume 58, Issue 11, pp. 2525 - 2532
Journal Article