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Science, ISSN 0036-8075, 12/2005, Volume 310, Issue 5753, pp. 1492 - 1495
Journal Article
Journal of leukocyte biology, ISSN 0741-5400, 08/2019
In innate immune cells, pathogens and danger signals activate TLRs, unleashing potent and tailored inflammatory responses. Previously, we reported that an... 
Journal Article
Cell Reports, ISSN 2211-1247, 09/2018, Volume 24, Issue 11, pp. 3033 - 3044
The multi-ligand endocytic receptor, low-density lipoprotein-receptor-related protein 1 (LRP1), has anti-inflammatory roles in disease. Here, we reveal that... 
LRP1 | crosstalk | inflammation | mTOR | macrophage | polarization | PI3Kγ | Akt | Rab8a | Toll-like receptor | SIGNAL-TRANSDUCTION | PULL-DOWN | CELLS | DOMAIN | TYROSINE PHOSPHORYLATION | PATHWAY | HUMAN MACROPHAGES | ADAPTER | RECEPTOR-RELATED PROTEIN-1 | NF-KAPPA-B | CELL BIOLOGY
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 7/1999, Volume 146, Issue 1, pp. 219 - 232
Journal Article
Traffic, ISSN 1398-9219, 09/2016, Volume 17, Issue 9, pp. 1014 - 1026
Journal Article
Journal Article
Small GTPases, ISSN 2154-1248, 2019, pp. 1 - 17
Macrophages are important immune sentinels that detect and clear pathogens and initiate inflammatory responses through the activation of surface receptors,... 
Rabin8 (Rab3IP) | Rab8 | inflammation | Toll-like receptor (TLR) | mTOR | macrophage | GEFs | Akt | GRAB (Rab3IL1) | PI3Kγ
Journal Article
Cytokine and Growth Factor Reviews, ISSN 1359-6101, 2013, Volume 24, Issue 3, pp. 227 - 239
Journal Article
Frontiers in Immunology, ISSN 1664-3224, 2014, Volume 5, p. 538
Macrophages have the capacity to rapidly secrete a wide range of inflammatory mediators that influence the development and extent of an inflammatory response.... 
Cytokine secretion | Rabs | SNAREs | Macrophages | TNF | IL-10 | IL-6 | REGULATED SECRETION | LYTIC GRANULES | FUSION | EXOCYTOSIS | ENDOSOME | IMMUNOLOGY | HUMAN MONOCYTES | macrophages | cytokine secretion | CHROMATIN PROTEIN HMGB1 | ACTIVATED MACROPHAGES | GTPASE | il-12
Journal Article