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Nature Chemical Biology, ISSN 1552-4450, 07/2016, Volume 12, Issue 7, pp. 539 - 545
Journal Article
Methods in molecular biology (Clifton, N.J.), 2019, Volume 2025, p. 281
Protein engineering has an array of uses: whether you are studying a disease mutation, removing undesirable sequences, adding stabilizing mutations for... 
Journal Article
Nature Communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 2210 - 8
The core machinery for de novo biosynthesis of iron-sulfur clusters (ISC), located in the mitochondria matrix, is a five-protein complex containing the... 
SYSTEM | BIOGENESIS | FRIEDREICHS-ATAXIA | BIOSYNTHESIS | ORIENTATION | MULTIDISCIPLINARY SCIENCES | VALIDATION | MODEL | MUTATIONS | REVEALS | Complex formation | Neurodegenerative diseases | Activation | Iron | Biosynthesis | Protein deficiency | Electron microscopy | Zinc | Proteins | Interfaces | Mitochondria | Frataxin | Ataxia | Mutation | Sulfur
Journal Article
Bioinformatics, ISSN 1367-4803, 01/2019, Volume 35, Issue 2, pp. 349 - 351
Abstract Summary SATurn is a modular, open-source, bioinformatics platform designed to specifically address the problems of maintenance and longevity commonly... 
BIOTECHNOLOGY & APPLIED MICROBIOLOGY | BIOCHEMICAL RESEARCH METHODS | MATHEMATICAL & COMPUTATIONAL BIOLOGY | Applications Notes
Journal Article
Journal Article
The Journal of Biological Chemistry, ISSN 0021-9258, 12/2014, Volume 289, Issue 52, pp. 36018 - 36030
Background: Human cystathionine β-synthase (hCBS) is activated by S -adenosyl- l -methionine (AdoMet). Results: We presented structural and solution evidence... 
Protein Structure and Folding | S-adenosyl-l-methionine (AdoMet) | Enzyme | Allosteric Regulation | Conformational Change | Mass Spectrometry (MS) | Activation | Crystallography | Cystathionine β-Synthase | SAM
Journal Article
Med. Chem. Commun, ISSN 2040-2503, 2014, Volume 5, Issue 4, pp. 540 - 546
A combination of conventional organic synthesis, remotely monitored flow synthesis and bioassay platforms, were used for the evaluation of novel inhibitors... 
Journal Article
MedChemComm, ISSN 2040-2503, 2014, Volume 5, Issue 4, pp. 540 - 546
A combination of conventional organic synthesis, remotely monitored flow synthesis and bioassay platforms, were used for the evaluation of novel inhibitors... 
CHEMISTRY, MEDICINAL | REACTOR | RECOGNITION | BIOCHEMISTRY & MOLECULAR BIOLOGY | INHIBITORS | LIGAND | TECHNOLOGY | DISCOVERY | BET BROMODOMAINS
Journal Article
Molecular Cell, ISSN 1097-2765, 05/2010, Volume 38, Issue 4, p. 563
Nicotinamide adenine dinucleotides have emerged as key signals of the cellular redox state. Yet the structural basis for allosteric gene regulation by the... 
Proteins | Purines | Niacinamide | Gene expression | DNA | Public health | Medical colleges | Molecular biology
Journal Article
Journal of Bacteriology, ISSN 0021-9193, 01/2010, Volume 192, Issue 2, p. 608
  Streptomyces coelicolor mutants lacking the zinc-responsive Zur repressor are conditionally defective in sporulation, presumably due to the overexpression of... 
Genotype & phenotype | Protein synthesis | Gram-positive bacteria | Mutation | Gene expression | Zinc | Bacteriology
Journal Article
Molecular Cell, ISSN 1097-2765, 05/2010, Volume 38, Issue 4
Journal Article
Chromatography, ISSN 2227-9075, 01/2014, Volume 1, Issue 4, pp. 159 - 175
  Mass spectrometry (MS) remains under-utilized for the analysis of expressed proteins because it is inaccessible to the non-specialist, and sample-turnaround... 
Proteins | Utilities | Purification | Pipelines | Biology | Mass spectrometry | Cost engineering | Recombinant | structural genomics | post-translational modification (PTM) | intact mass | high-throughput | mass spectrometry | integral membrane protein (IMP) | protein expression
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 2014, Volume 1091, pp. 95 - 121
Conference Proceeding
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