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Journal Article
PloS one, ISSN 1932-6203, 2019, Volume 14, Issue 8, pp. e0221676 - e0221676
Once a fixture of research in the social and behavioral sciences, volunteer subjects are now only rarely used in human subjects research. Yet volunteers are a... 
Volunteer workers in medical care | Social networks | Usage | Behavior | Research | Social aspects | Laboratories | Wages & salaries | Costs | Social sciences | International relations | Behavioral sciences | Experiments | Polls & surveys | Human subjects | Researchers | Quality | Computer supported cooperative work | Immigration | Internet | Human behavior | Volunteers | Index Medicus
Journal Article
by Beecham, Ashley H and Patsopoulos, Nikolaos A and Xifara, Dionysia K and Davis, Mary F and Kemppinen, Anu and Cotsapas, Chris and Shah, Tejas S and Spencer, Chris and Booth, David and Goris, An and Oturai, Annette and Saarela, Janna and Fontaine, Bertrand and Hemmer, Bernhard and Martin, Claes and Zipp, Frauke and D'Alfonso, Sandra and Martinelli-Boneschi, Filippo and Taylor, Bruce and Harbo, Hanne F and Kockum, Ingrid and Hillert, Jan and Olsson, Tomas and Ban, Maria and Oksenberg, Jorge R and Hintzen, Rogier and Barcellos, Lisa F and Agliardi, Cristina and Alfredsson, Lars and Alizadeh, Mehdi and Anderson, Carl and Andrews, Robert and Søndergaard, Helle Bach and Baker, Amie and Band, Gavin and Baranzini, Sergio E and Barizzone, Nadia and Barrett, Jeffrey and Bellenguez, Céline and Bergamaschi, Laura and Bernardinelli, Luisa and Berthele, Achim and Biberacher, Viola and Binder, Thomas M.C and Blackburn, Hannah and Bomfim, Izaura L and Brambilla, Paola and Broadley, Simon and Brochet, Bruno and Brundin, Lou and Buck, Dorothea and Butzkueven, Helmut and Caillier, Stacy J and Camu, William and Carpentier, Wassila and Cavalla, Paola and Celius, Elisabeth G and Coman, Irène and Comi, Giancarlo and Corrado, Lucia and Cosemans, Leentje and Cournu-Rebeix, Isabelle and Cree, Bruce A.C and Cusi, Daniele and Damotte, Vincent and Defer, Gilles and Delgado, Silvia R and Deloukas, Panos and Di Sapio, Alessia and Dilthey, Alexander T and Donnelly, Peter and Dubois, Bénédicte and Duddy, Martin and Edkins, Sarah and Elovaara, Irina and Esposito, Federica and Evangelou, Nikos and Fiddes, Barnaby and Field, Judith and Franke, Andre and Freeman, Colin and Frohlich, Irene Y and Galimberti, Daniela and Gieger, Christian and Gourraud, Pierre-Antoine and Graetz, Christiane and Graham, Andrew and Grummel, Verena and Guaschino, Clara and Hadjixenofontos, Athena and Hakonarson, Hakon and Halfpenny, Christopher and Hall, Gillian and Hall, Per and Hamsten, Anders and Harley, James and Harrower, Timothy and Hawkins, Clive and Hellenthal, Garrett and Hillier, Charles and ... and Wellcome Trust Case Control Consor and Int IBD Genetics Consortium IIBDGC and International Multiple Sclerosis Genetics Consortium (IMSGC) and Wellcome Trust Case Control Consortium 2 (WTCCC2) and International IBD Genetics Consortium (IIBDGC) and Institutionen för fysik, kemi och biologi and Linköpings universitet and Bioinformatik and Tekniska högskolan
Nature Genetics, ISSN 1061-4036, 2013, Volume 45, Issue 11, pp. 1353 - 1362
Journal Article
by Tsoi, L.C and Spain, S.L and Knight, J and Ellinghaus, E and Stuart, P.E and Capon, F and Ding, J and Li, J and Tejasvi, T and Gudjonsson, J.E and Kang, H and Allen, M.H and McManus, R and Novelli, G and Samuelsson, L and Schalkwijk, J and Stahle, M and Burden, A.D and Smith, C.H and Cork, M.J and Estivill, X and Bowcock, A and Krueger, G.G and Weger, W and Worthington, J and Tazi-Ahnini, R and Nestle, F.O and Hayday, A and Hoffmann, P and Winkelmann, J and Wijmenga, C and Langford, C and Edkins, S and Anews, R and Blackburn, H and Strange, A and Band, G and Pearson, R and Vukcevic, D and Spencer, C.C and Deloukas, P and Mrowietz, U and Schreiber, S and Weidinger, S and Koks, S and Kingo, K and Esko, T and Metspalu, A and Lim, H.W and Voorhees, J.J and Weichenthal, M and Wichmann, H.E and Chanan, V and Rosen, C.F and Rahman, P and Gladman, D.D and Griffiths, C.E and Reis, A and Kere, J and Duffin, K.C and Helms, C and Goldgar, D and Li, Y and Paschall, J and Malloy, M.J and Pullinger, C.R and Kane, J.P and Gardner, J and Perlmutter, A and Miner, A and Feng, B.J and Hiremagalore, R and Ike, R.W and Christophers, E and Henseler, T and Ruether, A and Schrodi, S.J and Prahalad, S and Guthery, S.L and Hiregalore, R and Donnelly, P and Collaborative Assoc Study Psoriasi and Psoriasis Assoc Genetics Extension and Genetic Anal Psoriasis Consortium and Wellcome Trust Case Control Consor and Psoriasis Association Genetics Extension and Genetic Analysis of Psoriasis Consortium and Collaborative Association Study of Psoriasis (CASP) and Wellcome Trust Case Control Consortium 2 and Sahlgrenska akademin and Institutionen för biomedicin, avdelningen för medicinsk genetik och klinisk genetik and Göteborgs universitet and Gothenburg University and Institute of Biomedicine, Department of Medical and Clinical Genetics and Sahlgrenska Academy
Nature Genetics, ISSN 1061-4036, 2012, Volume 44, Issue 12, pp. 1341 - 1348
To gain further insight into the genetic architecture of psoriasis, we conducted a meta-analysis of 3 genome-wide association studies (GWAS) and 2 independent... 
COMMON VARIANTS | SIGNALING PATHWAYS | MULTIPLE COMMON | INTERFERON-GAMMA | TH17 DIFFERENTIATION | GENETICS & HEREDITY | GENE-EXPRESSION | T-CELL DEVELOPMENT | GENOME-WIDE ASSOCIATION | CELIAC-DISEASE | NEGATIVE REGULATOR | Oligonucleotide Array Sequence Analysis | Humans | Immunity, Innate - genetics | Genetic Loci | CARD Signaling Adaptor Proteins - genetics | Psoriasis - genetics | Core Binding Factor Alpha 3 Subunit - immunology | STAT3 Transcription Factor - genetics | Skin - immunology | Psoriasis - immunology | CARD Signaling Adaptor Proteins - immunology | DEAD Box Protein 58 | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease | Genome-Wide Association Study | Guanylate Cyclase - immunology | Membrane Proteins - genetics | Membrane Proteins - immunology | GTPase-Activating Proteins - immunology | DEAD-box RNA Helicases - genetics | Core Binding Factor Alpha 3 Subunit - genetics | DEAD-box RNA Helicases - immunology | Guanylate Cyclase - genetics | T-Lymphocytes - immunology | Polymorphism, Single Nucleotide | GTPase-Activating Proteins - genetics | STAT3 Transcription Factor - immunology | Psoriasis | Physiological aspects | Disease susceptibility | Genetic aspects | Research | Autoimmune diseases | Gene expression | Chromosomes | Risk factors | Index Medicus | genetic analysis | innate immunity | Dermatologi och venereologi | Dermatology and Venereal Diseases | psoriasis
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2014, Volume 111, Issue 7, pp. 2626 - 2631
Mutations in leucine-rich repeat kinase 2 (LRRK2) cause inherited Parkinson disease (PD), and common variants around LRRK2 are a risk factor for sporadic PD.... 
Proteins | Neurites | Transfection | Neurons | Medical genetics | Parkinson disease | Disease risk | Genetic loci | Gene expression regulation | Genetic mutation | GAK | Trans-Golgi | BAG5 | Autophagy | RECRUITMENT | autophagy | PROTEIN | VARIANTS | LRRK2 | MULTIDISCIPLINARY SCIENCES | SEQUENCE | trans-Golgi | CLATHRIN | Cell Fractionation | Immunoprecipitation | Humans | Genetic Loci - genetics | Multiprotein Complexes - genetics | DNA Primers - genetics | Intracellular Signaling Peptides and Proteins - metabolism | Brain - metabolism | Multiprotein Complexes - metabolism | Mass Spectrometry | HEK293 Cells | Plasmids - genetics | Golgi Apparatus - ultrastructure | Protein-Serine-Threonine Kinases - metabolism | rab GTP-Binding Proteins - metabolism | Genetic Predisposition to Disease - genetics | Protein-Serine-Threonine Kinases - genetics | Blotting, Western | Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 | Microscopy, Confocal | Protein Interaction Mapping - methods | Analysis of Variance | Transport Vesicles - metabolism | Parkinson Disease - enzymology | Adaptor Proteins, Signal Transducing - metabolism | Genome-Wide Association Study - methods | Genetic aspects | Parkinson's disease | Leucine | Gene mutations | Health aspects | Phosphotransferases | Mutation | Kinases | Genes | Parkinsons disease | Index Medicus | Biological Sciences
Journal Article
by Ruderfer, Douglas M and Ripke, Stephan and McQuillin, Andrew and Boocock, James and Stahl, Eli A and Pavlides, Jennifer M. Whitehead and Mullins, Niamh and Charney, Alexander W and Ori, Anil P.S and Loohuis, Loes M. Olde and Domenici, Enrico and Di Florio, Arianna and Papiol, Sergi and Kalman, Janos L and Trubetskoy, Vassily and Adolfsson, Rolf and Agartz, Ingrid and Agerbo, Esben and Akil, Huda and Albani, Diego and Albus, Margot and Alda, Martin and Alexander, Madeline and Alliey-Rodriguez, Ney and Als, Thomas D and Amin, Farooq and Anjorin, Adebayo and Arranz, Maria J and Awasthi, Swapnil and Bacanu, Silviu A and Badner, Judith A and Baekvad-Hansen, Marie and Bakker, Steven and Band, Gavin and Barchas, Jack D and Barroso, Ines and Bass, Nicholas and Bauer, Michael and Baune, Bernhard T and Begemann, Martin and Bellenguez, Celine and Belliveau, Richard A and Bellivier, Frank and Bender, Stephan and Bene, Judit and Bergen, Sarah E and Berrettini, Wade H and Bevilacqua, Elizabeth and Biernacka, Joanna M and Bigdeli, Tim B and Black, Donald W and Blackburn, Hannah and Blackwell, Jenefer M and Blackwood, Douglas H.R and Pedersen, Marianne Giortz and Pedersen, Carsten Bocker and Boehnke, Michael and Boks, Marco and Borglum, Anders D and Bramon, Elvira and Breen, Gerome and Brown, Matthew A and Bruggeman, Richard and Buccola, Nancy G and Buckner, Randy L and Budde, Monika and Bulik-Sullivan, Brendan and Bumpstead, Suzannah J and Bunney, William and Burmeister, Margit and Buxbaum, Joseph D and Bybjerg-Grauholm, Jonas and Byerley, William and Cahn, Wiepke and Cai, Guiqing and Cairns, Murray J and Campion, Dominique and Cantor, Rita M and Carr, Vaughan J and Carrera, Noa and Casas, Miquel and Casas, Juan P and Catts, Stanley V and Cervantes, Pablo and Chambert, Kimberley D and Chan, Raymond C.K and Chen, Eric Y.H and Chen, Ronald Y.L and Cheng, Wei and Cheung, Eric F.C and Chong, Siow Ann and Clarke, Toni-Kim and Cloninger, C. Robert and Cohen, David and Cohen, Nadine and Coleman, Jonathan R.I and Collier, David A and Cormican, Paul and Coryell, William and Craddock, Nicholas and ... and Psychosis Endophenotypes Inter and Psychiat Genomics Consortium and Wellcome Trust Case-Control and Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium and Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium. Electronic address: douglas.ruderfer@vanderbilt.edu
Cell, ISSN 0092-8674, 06/2018, Volume 173, Issue 7, pp. 1705 - 1715.e16
Schizophrenia and bipolar disorder are two distinct diagnoses that share symptomology. Understanding the genetic factors contributing to the shared and... 
bipolar disorder | schizophrenia | subphenotypes | psychosis | polygenic risk | GWAS | GENE | DETERMINANTS | BIOCHEMISTRY & MOLECULAR BIOLOGY | DISEASE ASSOCIATIONS | PSYCHIATRIC-DISORDERS | RISK | WIDE ASSOCIATION | COPY NUMBER VARIATION | TRAITS | IDENTIFICATION | CELL BIOLOGY | Index Medicus
Journal Article
Journal of General Physiology, ISSN 0022-1295, 01/2009, Volume 133, Issue 1, pp. 29 - 42
Journal Article
by Su, Zhan and Gay, Laura J and Strange, Amy and Palles, Claire and Band, Gavin and Whiteman, David C and Lescai, Francesco and Langford, Cordelia and Nanji, Manoj and Edkins, Sarah and van der Winkel, Anouk and Levine, David and Sasieni, Peter and Bellenguez, Céline and Howarth, Kimberley and Freeman, Colin and Trudgill, Nigel and Tucker, Art T and Pirinen, Matti and Peppelenbosch, Maikel P and van der Laan, Luc J. W and Kuipers, Ernst J and nth, Joost P. H and Peters, Wilbert H and Reynolds, John V and Kelleher, Dermot P and McManus, Ross and Grabsch, Heike and Prenen, Hans and Bisschops, Raf and Krishnadath, Kausila and Siersema, Peter D and van Baal, Jantine W. P. M and Middleton, Mark and Petty, Russell and Gillies, Richard and Burch, Nicola and Bhandari, Pradeep and Paterson, Stuart and Edwards, Cathryn and Penman, Ian and Vaidya, Kishor and Ang, Yeng and Murray, Iain and Patel, Praful and Ye, Weimin and Mullins, Paul and Wu, Anna H and Bird, Nigel C and Dallal, Helen and Shaheen, Nicholas J and Murray, Liam J and Koss, Konrad and Bernstein, Leslie and Romero, Yvonne and Hardie, Laura J and Zhang, Rui and Winter, Helen and Corley, Douglas A and Panter, Simon and Risch, Harvey A and Reid, Brian J and Sargeant, Ian and Gammon, Marilie D and Smart, Howard and Dhar, Anjan and McMurtry, Hugh and Ali, Haythem and Liu, Geoffrey and Casson, Alan G and Chow, Wong-Ho and Rutter, Matt and Tawil, Ashref and Morris, Danielle and Nwokolo, Chuka and Isaacs, Peter and Rodgers, Colin and Ragunath, Krish and MacDonald, Chris and Haigh, Chris and Monk, David and Davies, Gareth and Wajed, Saj and Johnston, David and Gibbons, Michael and Cullen, Sue and Church, Nicholas and